메뉴 건너뛰기




Volumn 7, Issue 4, 2011, Pages 910-926

A Genome-Wide siRNA Screen Identifies Novel Phospho-enzymes Affecting Wnt/β-Catenin Signaling in Mouse Embryonic Stem Cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CATNB PROTEIN, MOUSE; PHOSPHATASE; PHOSPHOTRANSFERASE; SMALL INTERFERING RNA;

EID: 82355182845     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-011-9265-3     Document Type: Article
Times cited : (7)

References (86)
  • 1
    • 34447130140 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling
    • Cohen, E. D., Wang, Z., Lepore, J. J., et al. (2007). Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling. The Journal of Clinical Investigation, 117, 1794-1804.
    • (2007) The Journal of Clinical Investigation , vol.117 , pp. 1794-1804
    • Cohen, E.D.1    Wang, Z.2    Lepore, J.J.3
  • 2
    • 38949194936 scopus 로고    scopus 로고
    • Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
    • Zeng, X., Huang, H., Tamai, K., et al. (2008). Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development, 135, 367-375.
    • (2008) Development , vol.135 , pp. 367-375
    • Zeng, X.1    Huang, H.2    Tamai, K.3
  • 5
    • 0032941717 scopus 로고    scopus 로고
    • Regulation of LEF-1/TCF transcription factors by Wnt and other signals
    • Eastman, Q., & Grosschedl, R. (1999). Regulation of LEF-1/TCF transcription factors by Wnt and other signals. Current Opinion in Cell Biology, 11, 233-240.
    • (1999) Current Opinion in Cell Biology , vol.11 , pp. 233-240
    • Eastman, Q.1    Grosschedl, R.2
  • 6
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson, W. J., & Nusse, R. (2004). Convergence of Wnt, beta-catenin, and cadherin pathways. Science, 303, 1483-1487.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 7
    • 0031975738 scopus 로고    scopus 로고
    • The role of beta-catenin in cell adhesion, signal transduction, and cancer
    • Bullions, L. C., & Levine, A. J. (1998). The role of beta-catenin in cell adhesion, signal transduction, and cancer. Current Opinion in Oncology, 10, 81-87.
    • (1998) Current Opinion in Oncology , vol.10 , pp. 81-87
    • Bullions, L.C.1    Levine, A.J.2
  • 8
    • 39649111114 scopus 로고    scopus 로고
    • Intracellular signaling pathways regulating pluripotency of embryonic stem cells
    • Okita, K., & Yamanaka, S. (2006). Intracellular signaling pathways regulating pluripotency of embryonic stem cells. Current Stem Cell Research & Therapy, 1, 103-111.
    • (2006) Current Stem Cell Research & Therapy , vol.1 , pp. 103-111
    • Okita, K.1    Yamanaka, S.2
  • 9
    • 30544450976 scopus 로고    scopus 로고
    • WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells
    • Hao, J., Li, T. G., Qi, X., Zhao, D. F., & Zhao, G. Q. (2006). WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells. Developmental Biology, 290, 81-91.
    • (2006) Developmental Biology , vol.290 , pp. 81-91
    • Hao, J.1    Li, T.G.2    Qi, X.3    Zhao, D.F.4    Zhao, G.Q.5
  • 11
    • 7744241519 scopus 로고    scopus 로고
    • Wnt signaling and the regulation of stem cell function
    • Kleber, M., & Sommer, L. (2004). Wnt signaling and the regulation of stem cell function. Current Opinion in Cell Biology, 16, 681-687.
    • (2004) Current Opinion in Cell Biology , vol.16 , pp. 681-687
    • Kleber, M.1    Sommer, L.2
  • 12
    • 58249087390 scopus 로고    scopus 로고
    • New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening
    • Major, M. B., Roberts, B. S., Berndt, J. D., et al. (2008). New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening. Science Signaling, 1, ra12.
    • (2008) Science Signaling , vol.1
    • Major, M.B.1    Roberts, B.S.2    Berndt, J.D.3
  • 13
    • 41549119005 scopus 로고    scopus 로고
    • Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments
    • Klapholz-Brown, Z., Walmsley, G. G., Nusse, Y. M., Nusse, R., & Brown, P. O. (2007). Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments. PLoS ONE, 2, e945.
    • (2007) PLoS ONE , vol.2
    • Klapholz-Brown, Z.1    Walmsley, G.G.2    Nusse, Y.M.3    Nusse, R.4    Brown, P.O.5
  • 14
    • 67649220610 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling
    • James, R. G., Biechele, T. L., Conrad, W. H., et al. (2009). Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. Science Signaling, 2, ra25.
    • (2009) Science Signaling , vol.2
    • James, R.G.1    Biechele, T.L.2    Conrad, W.H.3
  • 16
    • 49449103510 scopus 로고    scopus 로고
    • Maintenance of undifferentiated mouse embryonic stem cells in suspension by the serum- and feeder-free defined culture condition
    • Tsuji, Y., Yoshimura, N., Aoki, H., et al. (2008). Maintenance of undifferentiated mouse embryonic stem cells in suspension by the serum- and feeder-free defined culture condition. Developmental Dynamics, 237, 2129-2138.
    • (2008) Developmental Dynamics , vol.237 , pp. 2129-2138
    • Tsuji, Y.1    Yoshimura, N.2    Aoki, H.3
  • 17
    • 0025834610 scopus 로고
    • Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum
    • Milner, R. E., Baksh, S., Shemanko, C., et al. (1991). Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum. The Journal of Biological Chemistry, 266, 7155-7165.
    • (1991) The Journal of Biological Chemistry , vol.266 , pp. 7155-7165
    • Milner, R.E.1    Baksh, S.2    Shemanko, C.3
  • 18
    • 77954056447 scopus 로고    scopus 로고
    • A direct phenotypic comparison of siRNA pools and multiple individual duplexes in a functional assay
    • Parsons, B. D., Schindler, A., Evans, D. H., & Foley, E. (2009). A direct phenotypic comparison of siRNA pools and multiple individual duplexes in a functional assay. PLoS ONE, 4, e8471.
    • (2009) PLoS ONE , vol.4
    • Parsons, B.D.1    Schindler, A.2    Evans, D.H.3    Foley, E.4
  • 19
    • 0037685280 scopus 로고    scopus 로고
    • Expression profiling reveals off-target gene regulation by RNAi
    • Jackson, A. L., Bartz, S. R., Schelter, J., et al. (2003). Expression profiling reveals off-target gene regulation by RNAi. Nature Biotechnology, 21, 635-637.
    • (2003) Nature Biotechnology , vol.21 , pp. 635-637
    • Jackson, A.L.1    Bartz, S.R.2    Schelter, J.3
  • 20
    • 18244377210 scopus 로고    scopus 로고
    • Wnt/beta-catenin pathway
    • cm1
    • Moon RT. Wnt/beta-catenin pathway. Sci STKE 2005; 271: cm1.
    • (2005) Sci STKE , vol.271
    • Moon, R.T.1
  • 21
    • 34147198467 scopus 로고    scopus 로고
    • Synthetic lethal screen identification of chemosensitizer loci in cancer cells
    • Whitehurst, A. W., Bodemann, B. O., Cardenas, J., et al. (2007). Synthetic lethal screen identification of chemosensitizer loci in cancer cells. Nature, 446, 815-819.
    • (2007) Nature , vol.446 , pp. 815-819
    • Whitehurst, A.W.1    Bodemann, B.O.2    Cardenas, J.3
  • 23
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh, Y. H., Wu, Q., Chew, J. L., et al. (2006). The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nature Genetics, 38, 431-440.
    • (2006) Nature Genetics , vol.38 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3
  • 25
    • 33745107507 scopus 로고    scopus 로고
    • Conserved roles for Oct4 homologues in maintaining multipotency during early vertebrate development
    • Morrison, G. M., & Brickman, J. M. (2006). Conserved roles for Oct4 homologues in maintaining multipotency during early vertebrate development. Development, 133, 2011-2022.
    • (2006) Development , vol.133 , pp. 2011-2022
    • Morrison, G.M.1    Brickman, J.M.2
  • 26
    • 0001584969 scopus 로고    scopus 로고
    • The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species
    • Smith, C. I., Islam, T. C., Mattsson, P. T., Mohamed, A. J., Nore, B. F., & Vihinen, M. (2001). The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species. Bioessays, 23, 436-446.
    • (2001) Bioessays , vol.23 , pp. 436-446
    • Smith, C.I.1    Islam, T.C.2    Mattsson, P.T.3    Mohamed, A.J.4    Nore, B.F.5    Vihinen, M.6
  • 27
    • 61849110214 scopus 로고    scopus 로고
    • Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk
    • Readinger, J. A., Mueller, K. L., Venegas, A. M., Horai, R., & Schwartzberg, P. L. (2009). Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk. Immunological Reviews, 228, 93-114.
    • (2009) Immunological Reviews , vol.228 , pp. 93-114
    • Readinger, J.A.1    Mueller, K.L.2    Venegas, A.M.3    Horai, R.4    Schwartzberg, P.L.5
  • 28
    • 21644445568 scopus 로고    scopus 로고
    • Myotubularin phosphoinositide phosphatases, protein phosphatases, and kinases: their roles in junction dynamics and spermatogenesis
    • Zhang, J., Mruk, D. D., & Cheng, C. Y. (2005). Myotubularin phosphoinositide phosphatases, protein phosphatases, and kinases: their roles in junction dynamics and spermatogenesis. Journal of Cellular Physiology, 204, 470-483.
    • (2005) Journal of Cellular Physiology , vol.204 , pp. 470-483
    • Zhang, J.1    Mruk, D.D.2    Cheng, C.Y.3
  • 29
    • 0031849995 scopus 로고    scopus 로고
    • Identification of connexin43 as a functional target for Wnt signalling
    • van der Heyden, M. A., Rook, M. B., Hermans, M. M., et al. (1998). Identification of connexin43 as a functional target for Wnt signalling. Journal of Cell Science, 111(Pt 12), 1741-1749.
    • (1998) Journal of Cell Science , vol.111 , Issue.Pt 12 , pp. 1741-1749
    • van der Heyden, M.A.1    Rook, M.B.2    Hermans, M.M.3
  • 30
    • 0032756584 scopus 로고    scopus 로고
    • Roles of Axin in the Wnt signalling pathway
    • Kikuchi, A. (1999). Roles of Axin in the Wnt signalling pathway. Cellular Signalling, 11, 777-788.
    • (1999) Cellular Signalling , vol.11 , pp. 777-788
    • Kikuchi, A.1
  • 31
    • 2442635410 scopus 로고    scopus 로고
    • Gastrin-mediated activation of cyclin D1 transcription involves beta-catenin and CREB pathways in gastric cancer cells
    • Pradeep, A., Sharma, C., Sathyanarayana, P., et al. (2004). Gastrin-mediated activation of cyclin D1 transcription involves beta-catenin and CREB pathways in gastric cancer cells. Oncogene, 23, 3689-3699.
    • (2004) Oncogene , vol.23 , pp. 3689-3699
    • Pradeep, A.1    Sharma, C.2    Sathyanarayana, P.3
  • 32
    • 0043210588 scopus 로고    scopus 로고
    • Duplexes of 21 nucleotide RNA specific for COX II mediates RNA interference in cultured bovine aortic coronary endothelial cells (BAECs)
    • Xiuzhu, T., Shore, L., Stram, Y., Michaeli, S. C., Brietbart, H. C., & Shemesh, M. (2003). Duplexes of 21 nucleotide RNA specific for COX II mediates RNA interference in cultured bovine aortic coronary endothelial cells (BAECs). Prostaglandins & Other Lipid Mediators, 71, 119-129.
    • (2003) Prostaglandins & Other Lipid Mediators , vol.71 , pp. 119-129
    • Xiuzhu, T.1    Shore, L.2    Stram, Y.3    Michaeli, S.C.4    Brietbart, H.C.5    Shemesh, M.6
  • 35
    • 77957669746 scopus 로고    scopus 로고
    • The role of FGF/Erk signaling in pluripotent cells
    • Lanner, F., & Rossant, J. (2010). The role of FGF/Erk signaling in pluripotent cells. Development, 137, 3351-3360.
    • (2010) Development , vol.137 , pp. 3351-3360
    • Lanner, F.1    Rossant, J.2
  • 36
    • 78751692388 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6
    • Cervenka, I., Wolf, J., Masek, J., et al. (2011). Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. Molecular and Cellular Biology, 31, 179-189.
    • (2011) Molecular and Cellular Biology , vol.31 , pp. 179-189
    • Cervenka, I.1    Wolf, J.2    Masek, J.3
  • 37
    • 73449139396 scopus 로고    scopus 로고
    • The NF-kappaB/AKT-dependent induction of Wnt signaling in colon cancer cells by macrophages and IL-1beta
    • Kaler P, Godasi BN, Augenlicht L, Klampfer L. The NF-kappaB/AKT-dependent induction of Wnt signaling in colon cancer cells by macrophages and IL-1beta. Cancer Microenviron 2009.
    • (2009) Cancer Microenviron
    • Kaler, P.1    Godasi, B.N.2    Augenlicht, L.3    Klampfer, L.4
  • 38
    • 24044500959 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells
    • Masckauchan, T. N., Shawber, C. J., Funahashi, Y., Li, C. M., & Kitajewski, J. (2005). Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells. Angiogenesis, 8, 43-51.
    • (2005) Angiogenesis , vol.8 , pp. 43-51
    • Masckauchan, T.N.1    Shawber, C.J.2    Funahashi, Y.3    Li, C.M.4    Kitajewski, J.5
  • 39
    • 30944461586 scopus 로고    scopus 로고
    • PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer
    • Mulholland, D. J., Dedhar, S., Wu, H., & Nelson, C. C. (2006). PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer. Oncogene, 25, 329-337.
    • (2006) Oncogene , vol.25 , pp. 329-337
    • Mulholland, D.J.1    Dedhar, S.2    Wu, H.3    Nelson, C.C.4
  • 40
    • 66449115036 scopus 로고    scopus 로고
    • PTEN, stem cells, and cancer stem cells
    • Hill, R., & Wu, H. (2009). PTEN, stem cells, and cancer stem cells. The Journal of Biological Chemistry, 284, 11755-11759.
    • (2009) The Journal of Biological Chemistry , vol.284 , pp. 11755-11759
    • Hill, R.1    Wu, H.2
  • 41
    • 51849086880 scopus 로고    scopus 로고
    • PTEN: a new guardian of the genome
    • Yin, Y., & Shen, W. H. (2008). PTEN: a new guardian of the genome. Oncogene, 27, 5443-5453.
    • (2008) Oncogene , vol.27 , pp. 5443-5453
    • Yin, Y.1    Shen, W.H.2
  • 42
    • 37049034663 scopus 로고    scopus 로고
    • The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals
    • Mani, M., Lee, S. Y., Lucast, L., et al. (2007). The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals. Neuron, 56, 1004-1018.
    • (2007) Neuron , vol.56 , pp. 1004-1018
    • Mani, M.1    Lee, S.Y.2    Lucast, L.3
  • 43
    • 34548643512 scopus 로고    scopus 로고
    • Phosphoinositide phosphatases in a network of signalling reactions
    • Blero, D., Payrastre, B., Schurmans, S., & Erneux, C. (2007). Phosphoinositide phosphatases in a network of signalling reactions. Pflugers Arch, 455, 31-44.
    • (2007) Pflugers Arch , vol.455 , pp. 31-44
    • Blero, D.1    Payrastre, B.2    Schurmans, S.3    Erneux, C.4
  • 44
    • 33746729798 scopus 로고    scopus 로고
    • Myotubularin phosphatases: policing 3-phosphoinositides
    • Robinson, F. L., & Dixon, J. E. (2006). Myotubularin phosphatases: policing 3-phosphoinositides. Trends in Cell Biology, 16, 403-412.
    • (2006) Trends in Cell Biology , vol.16 , pp. 403-412
    • Robinson, F.L.1    Dixon, J.E.2
  • 45
    • 17844371042 scopus 로고    scopus 로고
    • Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes
    • Ono, H., Katagiri, H., Funaki, M., et al. (2001). Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes. Molecular Endocrinology, 15, 1411-1422.
    • (2001) Molecular Endocrinology , vol.15 , pp. 1411-1422
    • Ono, H.1    Katagiri, H.2    Funaki, M.3
  • 46
    • 24144497139 scopus 로고    scopus 로고
    • Regulation of AKT1 expression by beta-catenin/Tcf/Lef signaling in colorectal cancer cells
    • Dihlmann, S., Kloor, M., Fallsehr, C., & von Knebel Doeberitz, M. (2005). Regulation of AKT1 expression by beta-catenin/Tcf/Lef signaling in colorectal cancer cells. Carcinogenesis, 26, 1503-1512.
    • (2005) Carcinogenesis , vol.26 , pp. 1503-1512
    • Dihlmann, S.1    Kloor, M.2    Fallsehr, C.3    von Knebel Doeberitz, M.4
  • 47
    • 63849147445 scopus 로고    scopus 로고
    • GSK-3 inhibitors and insulin receptor signaling in health, disease, and therapeutics
    • Wada, A. (2009). GSK-3 inhibitors and insulin receptor signaling in health, disease, and therapeutics. Frontiers in Bioscience, 14, 1558-1570.
    • (2009) Frontiers in Bioscience , vol.14 , pp. 1558-1570
    • Wada, A.1
  • 48
    • 70350492327 scopus 로고    scopus 로고
    • Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression
    • Dutta-Simmons, J., Zhang, Y., Gorgun, G., et al. (2009). Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression. Blood, 114, 2699-2708.
    • (2009) Blood , vol.114 , pp. 2699-2708
    • Dutta-Simmons, J.1    Zhang, Y.2    Gorgun, G.3
  • 49
    • 0033392360 scopus 로고    scopus 로고
    • Wnt signalling in mammalian development and cancer
    • Smalley, M. J., & Dale, T. C. (1999). Wnt signalling in mammalian development and cancer. Cancer and Metastasis Reviews, 18, 215-230.
    • (1999) Cancer and Metastasis Reviews , vol.18 , pp. 215-230
    • Smalley, M.J.1    Dale, T.C.2
  • 50
    • 0035719960 scopus 로고    scopus 로고
    • Wnt signaling in breast cancer: have we come full circle?
    • Brown, A. M. (2001). Wnt signaling in breast cancer: have we come full circle? Breast Cancer Research, 3, 351-355.
    • (2001) Breast Cancer Research , vol.3 , pp. 351-355
    • Brown, A.M.1
  • 51
    • 49549108896 scopus 로고    scopus 로고
    • Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin
    • Jin, T., George Fantus, I., & Sun, J. (2008). Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin. Cellular Signalling, 20, 1697-1704.
    • (2008) Cellular Signalling , vol.20 , pp. 1697-1704
    • Jin, T.1    George Fantus, I.2    Sun, J.3
  • 53
    • 68549123567 scopus 로고    scopus 로고
    • WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries?
    • Corbin, M., de Reynies, A., Rickman, D. S., et al. (2009). WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries? Genes, Chromosomes & Cancer, 48, 816-827.
    • (2009) Genes, Chromosomes & Cancer , vol.48 , pp. 816-827
    • Corbin, M.1    de Reynies, A.2    Rickman, D.S.3
  • 54
    • 0042809621 scopus 로고    scopus 로고
    • Regulation of hematopoietic stem cell self-renewal
    • Reya, T. (2003). Regulation of hematopoietic stem cell self-renewal. Recent Progress in Hormone Research, 58, 283-295.
    • (2003) Recent Progress in Hormone Research , vol.58 , pp. 283-295
    • Reya, T.1
  • 55
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • Sato, N., Meijer, L., Skaltsounis, L., Greengard, P., & Brivanlou, A. H. (2004). Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Natural Medicines, 10, 55-63.
    • (2004) Natural Medicines , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 56
    • 9144239955 scopus 로고    scopus 로고
    • Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling
    • Paling, N. R., Wheadon, H., Bone, H. K., & Welham, M. J. (2004). Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling. The Journal of Biological Chemistry, 279, 48063-48070.
    • (2004) The Journal of Biological Chemistry , vol.279 , pp. 48063-48070
    • Paling, N.R.1    Wheadon, H.2    Bone, H.K.3    Welham, M.J.4
  • 57
    • 33646549601 scopus 로고    scopus 로고
    • Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells
    • Watanabe, S., Umehara, H., Murayama, K., Okabe, M., Kimura, T., & Nakano, T. (2006). Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. Oncogene, 25, 2697-2707.
    • (2006) Oncogene , vol.25 , pp. 2697-2707
    • Watanabe, S.1    Umehara, H.2    Murayama, K.3    Okabe, M.4    Kimura, T.5    Nakano, T.6
  • 58
    • 51349144633 scopus 로고    scopus 로고
    • Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
    • Macurek, L., Lindqvist, A., Lim, D., et al. (2008). Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery. Nature, 455, 119-123.
    • (2008) Nature , vol.455 , pp. 119-123
    • Macurek, L.1    Lindqvist, A.2    Lim, D.3
  • 59
    • 0037048279 scopus 로고    scopus 로고
    • On the role of aurora-A in centrosome function
    • Dutertre, S., Descamps, S., & Prigent, C. (2002). On the role of aurora-A in centrosome function. Oncogene, 21, 6175-6183.
    • (2002) Oncogene , vol.21 , pp. 6175-6183
    • Dutertre, S.1    Descamps, S.2    Prigent, C.3
  • 60
    • 0032100685 scopus 로고    scopus 로고
    • A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
    • Bischoff, J. R., Anderson, L., Zhu, Y., et al. (1998). A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. The EMBO Journal, 17, 3052-3065.
    • (1998) The EMBO Journal , vol.17 , pp. 3052-3065
    • Bischoff, J.R.1    Anderson, L.2    Zhu, Y.3
  • 61
    • 58249111576 scopus 로고    scopus 로고
    • The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts
    • Amabile, G., D'Alise, A. M., Iovino, M., et al. (2009). The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts. Cell Death and Differentiation, 16, 321-330.
    • (2009) Cell Death and Differentiation , vol.16 , pp. 321-330
    • Amabile, G.1    D'Alise, A.M.2    Iovino, M.3
  • 62
    • 78651274358 scopus 로고    scopus 로고
    • Synthesis and transport of creatine in the CNS: importance for cerebral functions
    • Beard, E., & Braissant, O. (2010). Synthesis and transport of creatine in the CNS: importance for cerebral functions. Journal of Neurochemistry, 115, 297-313.
    • (2010) Journal of Neurochemistry , vol.115 , pp. 297-313
    • Beard, E.1    Braissant, O.2
  • 63
    • 63749088627 scopus 로고    scopus 로고
    • Local ATP generation by brain-type creatine kinase (CK-B) facilitates cell motility
    • Kuiper, J. W., van Horssen, R., Oerlemans, F., et al. (2009). Local ATP generation by brain-type creatine kinase (CK-B) facilitates cell motility. PLoS ONE, 4, e5030.
    • (2009) PLoS ONE , vol.4
    • Kuiper, J.W.1    van Horssen, R.2    Oerlemans, F.3
  • 64
    • 33846205505 scopus 로고    scopus 로고
    • Wnt signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation
    • Lowik, C. W., & van Bezooijen, R. L. (2006). Wnt signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation. Journal of Musculoskeletal & Neuronal Interactions, 6, 357.
    • (2006) Journal of Musculoskeletal & Neuronal Interactions , vol.6 , pp. 357
    • Lowik, C.W.1    van Bezooijen, R.L.2
  • 66
    • 39149116701 scopus 로고    scopus 로고
    • Brain creatine kinase activity in an animal model of mania
    • Streck, E. L., Amboni, G., Scaini, G., et al. (2008). Brain creatine kinase activity in an animal model of mania. Life Sciences, 82, 424-429.
    • (2008) Life Sciences , vol.82 , pp. 424-429
    • Streck, E.L.1    Amboni, G.2    Scaini, G.3
  • 67
    • 35548941791 scopus 로고    scopus 로고
    • Beta-catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells
    • Anton, R., Kestler, H. A., & Kuhl, M. (2007). Beta-catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells. FEBS Letters, 581, 5247-5254.
    • (2007) FEBS Letters , vol.581 , pp. 5247-5254
    • Anton, R.1    Kestler, H.A.2    Kuhl, M.3
  • 68
    • 33846643562 scopus 로고    scopus 로고
    • Canonical Wnt signaling transiently stimulates proliferation and enhances neurogenesis in neonatal neural progenitor cultures
    • Hirsch, C., Campano, L. M., Wohrle, S., & Hecht, A. (2007). Canonical Wnt signaling transiently stimulates proliferation and enhances neurogenesis in neonatal neural progenitor cultures. Experimental Cell Research, 313, 572-587.
    • (2007) Experimental Cell Research , vol.313 , pp. 572-587
    • Hirsch, C.1    Campano, L.M.2    Wohrle, S.3    Hecht, A.4
  • 69
    • 0033190523 scopus 로고    scopus 로고
    • Tec family of protein-tyrosine kinases: an overview of their structure and function
    • Mano, H. (1999). Tec family of protein-tyrosine kinases: an overview of their structure and function. Cytokine & Growth Factor Reviews, 10, 267-280.
    • (1999) Cytokine & Growth Factor Reviews , vol.10 , pp. 267-280
    • Mano, H.1
  • 71
    • 33750610840 scopus 로고    scopus 로고
    • Activation of Wnt/beta-catenin pathway during hepatocyte growth factor-induced hepatomegaly in mice
    • Apte, U., Zeng, G., Muller, P., et al. (2006). Activation of Wnt/beta-catenin pathway during hepatocyte growth factor-induced hepatomegaly in mice. Hepatology, 44, 992-1002.
    • (2006) Hepatology , vol.44 , pp. 992-1002
    • Apte, U.1    Zeng, G.2    Muller, P.3
  • 72
    • 0030989287 scopus 로고    scopus 로고
    • A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells
    • Austin, T. W., Solar, G. P., Ziegler, F. C., Liem, L., & Matthews, W. (1997). A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells. Blood, 89, 3624-3635.
    • (1997) Blood , vol.89 , pp. 3624-3635
    • Austin, T.W.1    Solar, G.P.2    Ziegler, F.C.3    Liem, L.4    Matthews, W.5
  • 74
    • 65649127710 scopus 로고    scopus 로고
    • Characterization of the phosphoinositide 3-kinase-dependent transcriptome in murine embryonic stem cells: identification of novel regulators of pluripotency
    • Storm, M. P., Kumpfmueller, B., Thompson, B., et al. (2009). Characterization of the phosphoinositide 3-kinase-dependent transcriptome in murine embryonic stem cells: identification of novel regulators of pluripotency. Stem Cells, 27, 764-775.
    • (2009) Stem Cells , vol.27 , pp. 764-775
    • Storm, M.P.1    Kumpfmueller, B.2    Thompson, B.3
  • 75
    • 62849093631 scopus 로고    scopus 로고
    • A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase
    • Wu, D., Pang, Y., Ke, Y., et al. (2009). A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase. PLoS ONE, 4, e4914.
    • (2009) PLoS ONE , vol.4
    • Wu, D.1    Pang, Y.2    Ke, Y.3
  • 76
    • 0141567655 scopus 로고    scopus 로고
    • A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis
    • Chan, R. J., Johnson, S. A., Li, Y., Yoder, M. C., & Feng, G. S. (2003). A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Blood, 102, 2074-2080.
    • (2003) Blood , vol.102 , pp. 2074-2080
    • Chan, R.J.1    Johnson, S.A.2    Li, Y.3    Yoder, M.C.4    Feng, G.S.5
  • 77
    • 0030797548 scopus 로고    scopus 로고
    • A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development
    • Qu, C. K., Shi, Z. Q., Shen, R., Tsai, F. Y., Orkin, S. H., & Feng, G. S. (1997). A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development. Molecular and Cellular Biology, 17, 5499-5507.
    • (1997) Molecular and Cellular Biology , vol.17 , pp. 5499-5507
    • Qu, C.K.1    Shi, Z.Q.2    Shen, R.3    Tsai, F.Y.4    Orkin, S.H.5    Feng, G.S.6
  • 78
    • 0032492954 scopus 로고    scopus 로고
    • Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta
    • Hart, M. J., de los Santos, R., Albert, I. N., Rubinfeld, B., & Polakis, P. (1998). Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. Current Biology, 8, 573-581.
    • (1998) Current Biology , vol.8 , pp. 573-581
    • Hart, M.J.1    de los Santos, R.2    Albert, I.N.3    Rubinfeld, B.4    Polakis, P.5
  • 79
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis, P. (2000). Wnt signaling and cancer. Genes & Development, 14, 1837-1851.
    • (2000) Genes & Development , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 80
    • 0344665680 scopus 로고    scopus 로고
    • Transgenic and knockout models of PP2A
    • Gotz, J., & Schild, A. (2003). Transgenic and knockout models of PP2A. Methods Enzymol, 366, 390-403.
    • (2003) Methods Enzymol , vol.366 , pp. 390-403
    • Gotz, J.1    Schild, A.2
  • 81
    • 77950890187 scopus 로고    scopus 로고
    • The protein tyrosine phosphatase PTP1B is required for efficient delivery of N-cadherin to the cell surface
    • Hernandez, M. V., Wehrendt, D. P., & Arregui, C. O. (2010). The protein tyrosine phosphatase PTP1B is required for efficient delivery of N-cadherin to the cell surface. Molecular Biology of the Cell, 21, 1387-1397.
    • (2010) Molecular Biology of the Cell , vol.21 , pp. 1387-1397
    • Hernandez, M.V.1    Wehrendt, D.P.2    Arregui, C.O.3
  • 82
    • 44349088690 scopus 로고    scopus 로고
    • Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation
    • Guo, W., Lasky, J. L., Chang, C. J., et al. (2008). Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation. Nature, 453, 529-533.
    • (2008) Nature , vol.453 , pp. 529-533
    • Guo, W.1    Lasky, J.L.2    Chang, C.J.3
  • 84
    • 14244270095 scopus 로고    scopus 로고
    • Regulation of Sertoli-germ cell adherens junction dynamics via changes in protein-protein interactions of the N-cadherin-beta-catenin protein complex which are possibly mediated by c-Src and myotubularin-related protein 2: an in vivo study using an androgen suppression model
    • Zhang, J., Wong, C. H., Xia, W., et al. (2005). Regulation of Sertoli-germ cell adherens junction dynamics via changes in protein-protein interactions of the N-cadherin-beta-catenin protein complex which are possibly mediated by c-Src and myotubularin-related protein 2: an in vivo study using an androgen suppression model. Endocrinology, 146, 1268-1284.
    • (2005) Endocrinology , vol.146 , pp. 1268-1284
    • Zhang, J.1    Wong, C.H.2    Xia, W.3
  • 85
    • 0141891208 scopus 로고    scopus 로고
    • Myotubularins, a large disease-associated family of cooperating catalytically active and inactive phosphoinositides phosphatases
    • Laporte, J., Bedez, F., Bolino, A., & Mandel, J. L. (2003). Myotubularins, a large disease-associated family of cooperating catalytically active and inactive phosphoinositides phosphatases. Human Molecular Genetics, 12(Spec No 2), 285-292.
    • (2003) Human Molecular Genetics , vol.12 , Issue.2 , pp. 285-292
    • Laporte, J.1    Bedez, F.2    Bolino, A.3    Mandel, J.L.4
  • 86
    • 33746960721 scopus 로고    scopus 로고
    • A critical role for endocytosis in Wnt signaling
    • Blitzer, J. T., & Nusse, R. (2006). A critical role for endocytosis in Wnt signaling. BMC Cell Biology, 7, 28.
    • (2006) BMC Cell Biology , vol.7 , pp. 28
    • Blitzer, J.T.1    Nusse, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.