Inhibition of the protein tyrosine phosphatase SHP-1 increases glucose uptake in skeletal muscle cells by augmenting insulin receptor signaling and GLUT4 expression

Endocrinology

Volumn 152, Issue 12, 2011, Pages 4581-4588

  Bergeron, Sébastien ^a   Dubois, Marie Julie ^a   Bellmann, Kerstin ^a   Schwab, Michael ^a   Larochelle, Nancy ^b   Nalbantoglu, Joséphine ^b   Marette, André ^a  

^a LAVAL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; DEOXYGLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN RECEPTOR; MESSENGER RNA; MUTANT PROTEIN; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL SURFACE; CONTROLLED STUDY; COXSACKIE VIRUS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; INSULIN METABOLISM; MOUSE; MUSCLE CELL; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ANIMALS; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; GLYCOGEN; MICE; MICE, TRANSGENIC; MUSCLE FIBERS, SKELETAL; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 82355165101     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1268     Document Type: Article

References (28)

1. Chang L, Chiang SH, Saltiel AR 2004 Insulin signaling and the regulation of glucose transport. Mol Med 10:65-71 (Pubitemid 41825486)
2. Ahmad F, Goldstein BJ 1997 Functional association between the insulin receptor and the transmembrane protein-tyrosine phosphatase LAR in intact cells. J Biol Chem 272:448-457 (Pubitemid 27021179)
3. Elchebly M, Payette P, Michaliszyn E, Cromlish W, Collins S, Loy AL, Normandin D, Cheng A, Himms-Hagen J, Chan CC, Ramachandran C, Gresser MJ, Tremblay ML, Kennedy BP 1999 Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. Science 283:1544-1548
4. Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, Stricker-Krongrad A, Shulman GI, Neel BG, Kahn BB 2000 Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Mol Cell Biol 20: 5479-5489 (Pubitemid 30482885)
5. Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB 2004 Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action. J Biol Chem 279:24844-24851 (Pubitemid 38725352)
6. Ren JM, Li PM, Zhang WR, Sweet LJ, Cline G, Shulman GI, Livingston JN, Goldstein BJ 1998 Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis. Diabetes 47:493-497 (Pubitemid 28104217)
7. Zabolotny JM, Kim YB, Peroni OD, Kim JK, Pani MA, Boss O, Klaman LD, Kamatkar S, Shulman GI, Kahn BB, Neel BG 2001 Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance. Proc Natl Acad Sci USA 98:5187-5192 (Pubitemid 32397104)
8. Zhang J, Somani AK, Siminovitch KA 2000 Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling. Semin Immunol 12:361-378
9. Kozlowski M, Mlinaric-Rascan I, Feng GS, Shen R, Pawson T, Siminovitch KA 1993 Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice. J Exp Med 178:2157-2163 (Pubitemid 23344873)
10. Shultz LD, Schweitzer PA, Rajan TV, Yi T, Ihle JN, Matthews RJ, Thomas ML, Beier DR 1993 Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 73:1445-1454 (Pubitemid 23201156)
11. Dubois MJ, Bergeron S, Kim HJ, Dombrowski L, Perreault M, Fournès B, Faure R, Olivier M, Beauchemin N, Shulman GI, Siminovitch KA, Kim JK, Marette A 2006 The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis. Nat Med 12:549-556
12. Dustin LB, Plas DR, Wong J, Hu YT, Soto C, Chan AC, Thomas ML 1999 Expression of dominant-negative src-homology domain 2-containing protein tyrosine phosphatase-1 results in increased Syk tyrosine kinase activity and B cell activation. J Immunol 162:2717-2724 (Pubitemid 29309294)
13. Nalbantoglu J, Larochelle N, Wolf E, Karpati G, Lochmuller H, Holland PC 2001 Muscle-specific overexpression of the adenovirus primary receptor CAR overcomes low efficiency of gene transfer to mature skeletal muscle. J Virol 75:4276-4282 (Pubitemid 32410140)
14. Bedard S, Marcotte B, Marette A 1997 Cytokines modulate glucose transport in skeletal muscle by inducing the expression of inducible nitric oxide synthase. Biochem J 325(Pt 2):487-493 (Pubitemid 27338732)
15. Ueyama A, Yaworsky KL, Wang Q, Ebina Y, Klip A 1999 GLUT- 4myc ectopic expression in L6 myoblasts generates a GLUT-4-specific pool conferring insulin sensitivity. Am J Physiol 277:E572-E578 (Pubitemid 29458219)
16. Haider SR, Wang W, Kaufman SJ 1994 SV40 T antigen inhibits expression of MyoD and myogenin, up-regulates Myf-5, but does not affect early expression of desmin or α7 integrin during muscle development. Exp Cell Res 210:278-286
17. Murata H, Hruz PW, Mueckler M 2002 Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations. AIDS 16:859-863 (Pubitemid 34409009)
18. Acsadi G, Jani A, Massie B, Simoneau M, Holland P, Blaschuk K, Karpati G 1994 A differential efficiency of adenovirus-mediated in vivo gene transfer into skeletal muscle cells of different maturity. Hum Mol Genet 3:579-584 (Pubitemid 24122170)
19. Feero WG, Rosenblatt JD, Huard J, Watkins SC, Epperly M, Clemens PR, Kochanek S, Glorioso JC, Partridge TA, Hoffman EP 1997 Viral gene delivery to skeletal muscle: insights on maturation-dependent loss of fiber infectivity for adenovirus and herpes simplex type 1 viral vectors. Hum Gene Ther 8:371-380 (Pubitemid 27140540)
20. Huard J, Lochmüller H, Acsadi G, Jani A, Holland P, Guérin C, Massie B, Karpati G 1995 Differential short-term transduction efficiency of adult versus newborn mouse tissues by adenoviral recombinants. Exp Mol Pathol 62:131-143 (Pubitemid 26045470)
21. Kass-Eisler A, Falck-Pedersen E, Elfenbein DH, Alvira M, Buttrick PM, Leinwand LA 1994 The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer. Gene Ther 1:395-402
22. Green MC, Shultz LD 1975 Motheaten, an immunodeficient mutant of the mouse. I . Genetics and pathology. J Hered 66:250-258
23. Shultz LD, Coman DR, Bailey CL, Beamer WG, Sidman CL 1984 "Viable motheaten," a new allele at the motheaten locus. I. Pathology. Am J Pathol 116:179-192 (Pubitemid 14053909)
24. McGee SL, van Denderen BJ, Howlett KF, Mollica J, Schertzer JD, Kemp BE, Hargreaves M 2008 AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5. Diabetes 57:860-867
25. Duchesne C, Charland S, Asselin C, Nahmias C, Rivard N 2003 Negative regulation of β-catenin signaling by tyrosine phosphatase SHP-1 in intestinal epithelial cells. J Biol Chem 278:14274-14283 (Pubitemid 36799976)
26. Henderson BR, Fagotto F 2002 The ins and outs of APC and β-catenin nuclear transport. EMBO Rep 3:834-839 (Pubitemid 35154107)
27. Atcha FA, Munguia JE, Li TW, Hovanes K, Waterman ML 2003 A new β-catenin-dependent activation domain in T cell factor. J Biol Chem 278:16169-16175 (Pubitemid 36799739)
28. Oshel KM, Knight JB, Cao KT, Thai MV, Olson AL 2000 Identification of a 30-base pair regulatory element and novel DNA binding protein that regulates the human GLUT4 promoter in transgenic mice. J Biol Chem 275:23666-23673 (Pubitemid 30624651)