Trichothecin induces apoptosis of HepG2 cells via caspase-9 mediated activation of the mitochondrial death pathway

Toxicon

Volumn 59, Issue 1, 2012, Pages 143-150

  Du, Rong Hui ^a   Cui, Jiang Tao ^a   Wang, Ting ^a   Zhang, Ai Hua ^a   Tan, Ren Xiang ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Apoptosis; Ca 2+ overload; Caspase 9; Reactive oxidative stress; Trichothecin

Indexed keywords

CALCIUM ION; CASPASE 3; CASPASE 9; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TRICHOTHECENE;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DAMAGE; CELL STRAIN HEPG2; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; HOMOSOMAL CONDENSATION; IN VITRO STUDY; INTER NUCLEOSOMAL FRAGMENTATION; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; CALCIUM; CASPASE 3; CASPASE 9; HEP G2 CELLS; HUMANS; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRICHOTHECENES;

ANIMALIA;

EID: 82255195394     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2011.11.003     Document Type: Article

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