메뉴 건너뛰기




Volumn 101, Issue 1, 2012, Pages 116-126

Identification of novel nonsteroidal compounds as substrates or inhibitors of hASBT

Author keywords

ASBT; Bile acid; Inhibitor; Nonsteroidal; Prodrug; Substrate

Indexed keywords

BILE ACID CONJUGATE; HUMAN APICAL SODIUM DEPENDENT BILE ACID TRANSPORTER; UNCLASSIFIED DRUG;

EID: 82255191710     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22728     Document Type: Article
Times cited : (6)

References (24)
  • 1
    • 70849133150 scopus 로고    scopus 로고
    • Bile acid transporters
    • Dawson PA, Lan T, Rao A. 2009. Bile acid transporters. J Lipid Res 50(12):2340-2357.
    • (2009) J Lipid Res , vol.50 , Issue.12 , pp. 2340-2357
    • Dawson, P.A.1    Lan, T.2    Rao, A.3
  • 2
    • 33745769730 scopus 로고    scopus 로고
    • Apical sodium dependent bile acid transporter (ASBT, SLC10A2): A potential prodrug target
    • Balakrishnan A, Polli JE. 2006. Apical sodium dependent bile acid transporter (ASBT, SLC10A2): A potential prodrug target. Mol Pharm 3(3):223-230.
    • (2006) Mol Pharm , vol.3 , Issue.3 , pp. 223-230
    • Balakrishnan, A.1    Polli, J.E.2
  • 3
    • 4544232586 scopus 로고    scopus 로고
    • Increased acyclovir oral bioavailability via a bile acid conjugate
    • Tolle-Sander S, Lentz KA, Maeda DY, Coop A, Polli JE. 2004. Increased acyclovir oral bioavailability via a bile acid conjugate. Mol Pharm 1(1):40-48.
    • (2004) Mol Pharm , vol.1 , Issue.1 , pp. 40-48
    • Tolle-Sander, S.1    Lentz, K.A.2    Maeda, D.Y.3    Coop, A.4    Polli, J.E.5
  • 4
    • 69149106367 scopus 로고    scopus 로고
    • Bile acids have the gall to function as hormones
    • Vallim TQ, Edwards PA. 2009. Bile acids have the gall to function as hormones. Cell Metab 10(3):162-164.
    • (2009) Cell Metab , vol.10 , Issue.3 , pp. 162-164
    • Vallim, T.Q.1    Edwards, P.A.2
  • 5
    • 77953403465 scopus 로고    scopus 로고
    • Bile-induced secretion of glucagon-like peptide-1: Pathophysiological implications in type 2 diabetes
    • Knop FK. 2010. Bile-induced secretion of glucagon-like peptide-1: Pathophysiological implications in type 2 diabetes? Am J Physiol Endocrinol Metab 299(1):E10-E13.
    • (2010) Am J Physiol Endocrinol Metab , vol.299 , Issue.1
    • Knop, F.K.1
  • 6
    • 77958004743 scopus 로고    scopus 로고
    • Counter-regulatory role of bile acid activated receptors in immunity and inflammation
    • Fiorucci S, Cipriani S, Mencarelli A, Renga B, Distrutti E, Baldelli F. 2010. Counter-regulatory role of bile acid activated receptors in immunity and inflammation. Curr Mol Med 10(6):579-595.
    • (2010) Curr Mol Med , vol.10 , Issue.6 , pp. 579-595
    • Fiorucci, S.1    Cipriani, S.2    Mencarelli, A.3    Renga, B.4    Distrutti, E.5    Baldelli, F.6
  • 7
    • 0029863605 scopus 로고    scopus 로고
    • Metabolism of orally administered tauroursodeoxycholic acid in patients with primary biliary cirrhosis
    • Setchell KD, Rodrigues CM, Podda M, Crosignani A. 1996. Metabolism of orally administered tauroursodeoxycholic acid in patients with primary biliary cirrhosis. Gut 38(3):439-446.
    • (1996) Gut , vol.38 , Issue.3 , pp. 439-446
    • Setchell, K.D.1    Rodrigues, C.M.2    Podda, M.3    Crosignani, A.4
  • 8
    • 33644843831 scopus 로고    scopus 로고
    • Computational approaches to modeling drug transporters
    • Chang C, Swaan PW. 2006. Computational approaches to modeling drug transporters. Eur J Pharm Sci 27(5):411-424.
    • (2006) Eur J Pharm Sci , vol.27 , Issue.5 , pp. 411-424
    • Chang, C.1    Swaan, P.W.2
  • 9
    • 0031265897 scopus 로고    scopus 로고
    • Molecular modeling of the intestinal bile acid carrier: A comparative molecular field analysis study
    • Swaan PW, Szoka FC Jr., Oie S. 1997. Molecular modeling of the intestinal bile acid carrier: A comparative molecular field analysis study. J Comput Aided Mol Des 11(6):581-588.
    • (1997) J Comput Aided Mol Des , vol.11 , Issue.6 , pp. 581-588
    • Swaan, P.W.1    Szoka, F.J.2    Oie, S.3
  • 10
    • 0033380340 scopus 로고    scopus 로고
    • Substrate specificity of the ileal and the hepatic Na(+)/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na(+)/bile acid cotransporter
    • Baringhaus KH, Matter H, Stengelin S, Kramer W. 1999. Substrate specificity of the ileal and the hepatic Na(+)/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na(+)/bile acid cotransporter. J Lipid Res 40(12):2158-2168.
    • (1999) J Lipid Res , vol.40 , Issue.12 , pp. 2158-2168
    • Baringhaus, K.H.1    Matter, H.2    Stengelin, S.3    Kramer, W.4
  • 11
    • 78649971657 scopus 로고    scopus 로고
    • Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates
    • Rais R, Acharya C, Mackerell AD, Polli JE. 2010. Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates. Mol Pharm 7(6):2240-2254.
    • (2010) Mol Pharm , vol.7 , Issue.6 , pp. 2240-2254
    • Rais, R.1    Acharya, C.2    Mackerell, A.D.3    Polli, J.E.4
  • 12
    • 78649305796 scopus 로고    scopus 로고
    • Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid
    • Zheng X, Pan Y, Acharya C, Swaan PW, Polli JE. 2010. Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid. Bioconjug Chem 21(11):2038-2048.
    • (2010) Bioconjug Chem , vol.21 , Issue.11 , pp. 2038-2048
    • Zheng, X.1    Pan, Y.2    Acharya, C.3    Swaan, P.W.4    Polli, J.E.5
  • 13
    • 5244364312 scopus 로고    scopus 로고
    • The information content of 2D and 3D structural descriptors relevant to ligand-receptor binding
    • Brown RD, Martin YC. 1997. The information content of 2D and 3D structural descriptors relevant to ligand-receptor binding. J Chem Inf Comput Sci 37(1):1-9.
    • (1997) J Chem Inf Comput Sci , vol.37 , Issue.1 , pp. 1-9
    • Brown, R.D.1    Martin, Y.C.2
  • 14
    • 0032671931 scopus 로고    scopus 로고
    • Unsupervised data base clustering based on Daylight's fingerprint and Tanimoto similarity: A fast and automated way to cluster small and large data sets
    • Butina D. 1999. Unsupervised data base clustering based on Daylight's fingerprint and Tanimoto similarity: A fast and automated way to cluster small and large data sets. J Chem Inf Comput Sci 39(4):747-750.
    • (1999) J Chem Inf Comput Sci , vol.39 , Issue.4 , pp. 747-750
    • Butina, D.1
  • 15
    • 0041903760 scopus 로고    scopus 로고
    • Design and evaluation of a molecular fingerprint involving the transformation of property descriptor values into a binary classification scheme
    • Xue L, Godden JW, Stahura FL, Bajorath J. 2003. Design and evaluation of a molecular fingerprint involving the transformation of property descriptor values into a binary classification scheme. J Chem Inf Comput Sci 43(4):1151-1157.
    • (2003) J Chem Inf Comput Sci , vol.43 , Issue.4 , pp. 1151-1157
    • Xue, L.1    Godden, J.W.2    Stahura, F.L.3    Bajorath, J.4
  • 16
    • 33745799433 scopus 로고    scopus 로고
    • Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter
    • Balakrishnan A, Wring SA, Coop A, Polli JE. 2006. Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter. Mol Pharm 3(3):282-292.
    • (2006) Mol Pharm , vol.3 , Issue.3 , pp. 282-292
    • Balakrishnan, A.1    Wring, S.A.2    Coop, A.3    Polli, J.E.4
  • 17
    • 0018618693 scopus 로고
    • Properties and biological significance of the ileal bile salt transport system
    • Lack L. 1979. Properties and biological significance of the ileal bile salt transport system. Environ Health Perspect 33:79-89.
    • (1979) Environ Health Perspect , vol.33 , pp. 79-89
    • Lack, L.1
  • 18
    • 23844510921 scopus 로고    scopus 로고
    • Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT)
    • Balakrishnan A, Sussman DJ, Polli JE. 2005. Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT). Pharm Res 22(8):1269-1280.
    • (2005) Pharm Res , vol.22 , Issue.8 , pp. 1269-1280
    • Balakrishnan, A.1    Sussman, D.J.2    Polli, J.E.3
  • 19
    • 67349278539 scopus 로고    scopus 로고
    • Inhibition requirements of the human apical sodium-dependent bile acid transporter (hASBT) using aminopiperidine conjugates of glutamyl-bile acids
    • Gonzalez PM, Acharya C, Mackerell AD Jr., Polli JE. 2009. Inhibition requirements of the human apical sodium-dependent bile acid transporter (hASBT) using aminopiperidine conjugates of glutamyl-bile acids. Pharm Res 26(7):1665-1678.
    • (2009) Pharm Res , vol.26 , Issue.7 , pp. 1665-1678
    • Gonzalez, P.M.1    Acharya, C.2    Mackerell Jr, A.D.3    Polli, J.E.4
  • 20
    • 33845873385 scopus 로고    scopus 로고
    • Bias in estimation of transporter kinetic parameters from overexpression systems: Interplay of transporter expression level and substrate affinity
    • Balakrishnan A, Hussainzada N, Gonzalez P, Bermejo M, Swaan PW, Polli JE. 2007. Bias in estimation of transporter kinetic parameters from overexpression systems: Interplay of transporter expression level and substrate affinity. J Pharmacol Exp Ther 320(1):133-144.
    • (2007) J Pharmacol Exp Ther , vol.320 , Issue.1 , pp. 133-144
    • Balakrishnan, A.1    Hussainzada, N.2    Gonzalez, P.3    Bermejo, M.4    Swaan, P.W.5    Polli, J.E.6
  • 21
    • 0032567523 scopus 로고    scopus 로고
    • Bile acid uptake via the human apical sodium-bile acid cotransporter is electrogenic
    • Weinman SA, Carruth MW, Dawson PA. 1998. Bile acid uptake via the human apical sodium-bile acid cotransporter is electrogenic. J Biol Chem 273(52):34691-34695.
    • (1998) J Biol Chem , vol.273 , Issue.52 , pp. 34691-34695
    • Weinman, S.A.1    Carruth, M.W.2    Dawson, P.A.3
  • 22
    • 65549143367 scopus 로고    scopus 로고
    • Method to screen substrates of apical sodium-dependent bile acid transporter
    • Rais R, Gonzalez PM, Zheng X, Wring SA, Polli JE. 2008. Method to screen substrates of apical sodium-dependent bile acid transporter. AAPS J 10(4):596-605.
    • (2008) AAPS J , vol.10 , Issue.4 , pp. 596-605
    • Rais, R.1    Gonzalez, P.M.2    Zheng, X.3    Wring, S.A.4    Polli, J.E.5
  • 23
    • 33745584351 scopus 로고    scopus 로고
    • Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): Influence of steroidal hydroxylation pattern and C-24 conjugation
    • Balakrishnan A, Wring SA, Polli JE. 2006. Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): Influence of steroidal hydroxylation pattern and C-24 conjugation. Pharm Res 23(7):1451-1459.
    • (2006) Pharm Res , vol.23 , Issue.7 , pp. 1451-1459
    • Balakrishnan, A.1    Wring, S.A.2    Polli, J.E.3
  • 24
    • 49449106497 scopus 로고    scopus 로고
    • Current and future pharmacologic options for the management of patients unable to achieve low-density lipoprotein-cholesterol goals with statins
    • El Harchaoui K, Akdim F, Stroes ES, Trip MD, Kastelein JJ. 2008. Current and future pharmacologic options for the management of patients unable to achieve low-density lipoprotein-cholesterol goals with statins. Am J Cardiovasc Drugs 8(4):233-242.
    • (2008) Am J Cardiovasc Drugs , vol.8 , Issue.4 , pp. 233-242
    • El, H.K.1    Akdim, F.2    Stroes, E.S.3    Trip, M.D.4    Kastelein, J.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.