Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid

Bioconjugate Chemistry

Volumn 21, Issue 11, 2010, Pages 2038-2048

  Zheng, Xiaowan ^a   Pan, Yongmei ^a   Acharya, Chayan ^a,b   Swaan, Peter W ^a   Polli, James E ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b INSTITUT EUROPÉEN DE CHIMIE ET BIOLOGIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BODY FLUIDS; COMPUTATIONAL CHEMISTRY; SUBSTRATES;

3D-QSAR; AMINOPYRIDINES; BILE ACID; CHENODEOXYCHOLIC ACID; DRUG TARGETS; HYDROPHOBICS; INHIBITION MODELS; QSAR ANALYSIS; STERICS; STRUCTURAL REQUIREMENTS;

HYDROPHOBICITY;

AMINOPYRIDINE; APICAL SODIUM DEPENDENT BILE ACID TRANSPORTER; CHENODEOXYCHOLIC ACID; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DRUG INHIBITION; DRUG SYNTHESIS; DRUG TARGETING; HYDROPHOBICITY; PROTEIN BINDING; PROTEIN TRANSPORT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

EID: 78649305796     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc100273w     Document Type: Article

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