Poststernotomy pain: A clinical review

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 25, Issue 6, 2011, Pages 1163-1178

  Mazzeffi, Michael ^a   Khelemsky, Yury ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

cardiac surgery; pain; sternotomy

Indexed keywords

ALFENTANIL; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ANESTHETIC AGENT; BUPIVACAINE; CLONIDINE; DICLOFENAC; FENTANYL; GABAPENTIN; HYDROMORPHONE; KETAMINE; LOCAL ANESTHETIC AGENT; MAGNESIUM; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; OXYCODONE; PARACETAMOL; PARECOXIB; PETHIDINE; PLACEBO; PREGABALIN; PROPACETAMOL; REMIFENTANIL; ROPIVACAINE; SUFENTANIL; TRAMADOL; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VALDECOXIB;

BLEEDING; BRAIN; BRAIN STEM; BRONCHOSPASM; CARDIOVASCULAR DISEASE; CHRONIC PAIN; CONSTIPATION; CONTINUOUS INFUSION; CORONARY ARTERY BYPASS GRAFT; COUGHING; DELIRIUM; DIZZINESS; DRUG MECHANISM; DRUG MEGADOSE; DYSPHORIA; EPIDURAL HEMATOMA; FACIAL EXPRESSION; GENERAL ANESTHESIA; HALLUCINATION; HEART SURGERY; HOSPITAL POLICY; HUMAN; HYPERSALIVATION; HYPOTENSION; ILEUS; INTERMETHOD COMPARISON; LOADING DRUG DOSE; MEDICAL LITERATURE; MINIMALLY INVASIVE SURGERY; MORNING DOSAGE; NAUSEA; NAUSEA AND VOMITING; NERVE BLOCK; NEUROPATHIC PAIN; OFF PUMP CORONARY SURGERY; PARAVERTEBRAL BLOCK; PATHOPHYSIOLOGY; PATIENT CONTROLLED ANALGESIA; PATIENT EDUCATION; PATIENT MOBILITY; PATIENT SATISFACTION; PERIPHERAL NERVE; POSTOPERATIVE PAIN; PREOPERATIVE EDUCATION; PRIORITY JOURNAL; PRURITUS; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL (TOPIC); RATING SCALE; REGIONAL ANESTHESIA; RESPIRATION DEPRESSION; REVIEW; RISK BENEFIT ANALYSIS; SEDATION; SIDE EFFECT; SINGLE DRUG DOSE; SPINAL CORD; SPINAL NERVE; STERNOTOMY; SURGICAL TECHNIQUE; SWEATING; SYSTEMATIC REVIEW; TACHYCARDIA; THORAX EPIDURAL ANESTHESIA; THORAX PAIN; THORAX WALL; THROMBOSIS; TISSUE INJURY; TRANSCUTANEOUS NERVE STIMULATION; TREATMENT OUTCOME; URINE RETENTION; VISUAL ANALOG SCALE; VOMITING;

ACUTE DISEASE; ANALGESICS; ANALGESICS, OPIOID; ANESTHESIA, CONDUCTION; ANESTHESIA, EPIDURAL; CARDIAC SURGICAL PROCEDURES; CHRONIC DISEASE; DRUG THERAPY, COMBINATION; ELECTROACUPUNCTURE; HUMANS; INJECTIONS, SPINAL; PAIN, POSTOPERATIVE; PATIENT EDUCATION AS TOPIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; STERNOTOMY; TRANSCUTANEOUS ELECTRIC NERVE STIMULATION;

EID: 82255179409     PISSN: 10530770     EISSN: 15328422     Source Type: Journal    
DOI: 10.1053/j.jvca.2011.08.001     Document Type: Review

References (175)

1. S.S. Liu, and C.L. Wu Effect of postoperative analgesia on major postoperative complications: A systematic update of the evidence Anesth Analg 104 2007 689 702
2. Heart Disease and Stroke Statistics: 2010 Update at a glance 2010 American Heart Association Dallas, TX 1 20
3. D.A. Meehan, M.E. McRae, and D.A. Rourke Analgesic administration, pain intensity, and patient satisfaction in cardiac surgical patients Am J Crit Care 4 1995 435 442
4. K.A. Puntillo Pain experiences of intensive care unit patients Heart Lung 19 1990 526 533
5. S.W. Valdix, and K.A. Puntillo Pain, pain relief and accuracy of their recall after cardiac surgery Prog Cardiovasc Nurs 10 1995 3 11
6. P. Lahtinen, H. Kokki, and M. Hynynen Pain after cardiac surgery Anesthesiology 105 2006 794 800
7. L.B. Milgrom, J.A. Brooks, and R. Qi Pain levels experienced with activities after cardiac surgery Am J Crit Care 13 2004 116 125
8. X.M. Mueller, F. Tinguely, and H.T. Tevaearai Pain location, distribution, and intensity after cardiac surgery Chest 188 2000 391 396
9. J. York, G. Dip, and M. Wallis Patients' perceptions of pain management after cardiac surgery in an Australian critical care unit Heart Lung 33 2004 33 41
10. Y. Jammes, D. Trousse, and S. Delpierre Identification and properties of parietal pleural afferents in rabbits J Physiol 567 2005 641 650
11. A.S. Weissbein, and F.N. Heller A method of treatment for pericardial pain Circulation 24 1961 607 612
12. B.L. Kidd, and L.A. Urban Mechanisms of inflammatory pain Br J Anaesth 87 2001 3 11
13. J.M. Besson The neurobiology of pain Lancet 353 1999 1610 1615
14. J. Cogan Pain management after cardiac surgery Semin Cardiothorac Vasc Anesth 14 2010 201 204
15. A.B. Sasseron, L.C. Figueiredo, and K. Trova Does the pain disturb respiratory function after heart surgeries? Rev Bras Cir Cardiovasc 24 2009 490 496
16. R. Gust, S. Pecher, and A. Gust Effect of patient controlled analgesia on pulmonary complications after coronary artery bypass grafting Crit Care Med 27 1999 2218 2223
17. C.J. OConnor Pain Relief and pulmonary morbidity after cardiac surgery Crit Care Med 27 1999 2314 2316
18. Z. Shenkman, Y. Shir, and Y.G. Weiss The effects of cardiac surgery on early and late pulmonary functions Acta Anaesthesiol Scand 41 1997 1193 1199
19. T.J. Locke, T.L. Griffiths, and H. Mould Rib cage mechanics after median sternotomy Thorax 45 1990 465 468
20. F.S. Vargas, A. Cukier, and M. Terra-Filho Influence of atelectasis on pulmonary function after coronary artery bypass grafting Chest 104 1993 434 437
21. L. Magnusson, V. Zemgulis, and S. Wicky Atelectasis is a major source of hypoxemia and shunt after cardiopulmonary bypass: An experimental study Anesthesiology 87 1996 1153 1163
22. P.D. Macnaughton, S. Braude, and D.N. Hunter Changes in lung function and pulmonary capillary permeability after cardiopulmonary bypass Crit Care Med 20 1992 1289 1294
23. T. Hachenberg, A. Tenling, and S.O. Nyström Ventilation-perfusion inequality in patients undergoing cardiac surgery Anesthesiology 80 1994 509 519
24. T.J. Duellman, C. Gaffigan, and J.C. Mibrandt Multi-modal pre-emptive analgesia decreases the length of hospital stay following total joint arthroplasty Orthopedics 32 2009 167
25. D.C. Mears, S.C. Mears, and J.E. Chelly THA with a minimally invasive technique, multi-modal anesthesia, and home rehabilitation: Factors associated with early discharge? Clin Orthop Relat Res 467 2009 1412 1417
26. B. Ben-David, J. Swanson, and J.B. Nelson Multimodal analgesia for radical prostatectomy provides better analgesia and shortens hospital stay J Clin Anesth 19 2007 264 268
27. L.I. Janssen-Sanders, L.V. Gulik, and P. Bruins Pain in intensive care after sternotomy is predictive of chronic thoracic pain Crit Care 12 suppl 2 2008 510
28. P.E. Macintyre Safety and efficacy of patient-controlled analgesia Br J Anaesth 87 2001 36 46
29. B. Walder, M. Schafer, and I. Henzi Efficacy and safety of patient controlled opioid analgesia for acute post-operative pain A quantitative systematic review Acta Anaesthesiol Scand 45 2001 795 804
30. P.H. Pettersson, A. Lindskog, and A. Owall Patient-controlled versus nurse-controlled pain treatment after coronary artery buypass grafting Acta Anaesthesiol Scand 44 2000 43 47
31. H.A. Aitken, and G.N.C. Kenny Use of patient controlled analgesia in postoperative cardiac surgical patients-a survey of ward staff attitudes Intesive Care Nurs 6 1990 74 78
32. D.S. Oztekin, I. Oztekin, and H. Issever Postoperative effects of opioid analgesics administered via continuous perfusion and patient controlled analgesia after open heart surgery Yakugaku Zasshi 26 2006 499 504
33. A. Gurbet, S. Goren, and S. Sahin Comparison of analgesic effects of morphine, fentanyl, and remifentanil with intravenous patient controlled analgesia after cardiac surgery J Cardiothorac Vasc Anesth 18 2004 755 758
34. M.R. Checketts, C.J. Gilhooly, and G.N.C. Kenny Patient-maintained analgesia with target-controlled alfentanil infusion after cardiac surgery: A comparison with morphine Br J Anaesth 80 1998 748 751
35. T. Guler, H. Unlugenc, and Z. Gundogan A background infusion of morphine enhances patient-controlled analgesia after cardiac surgery Can J Anaesth 51 2004 718 722
36. F.A. Mota, J.F. Marcolan, and M.H. Pereira Comparison study of two different patient-controlled anesthesia regimens after cardiac surgery Rev Bras Cir Cardiovasc 25 2010 38 44
37. D. Dal, M. Kanbak, and M. Caglar A background infusion of morphine does not enhance postoperative analgesia after cardiac surgery Can J Anaesth 50 2003 476 479
38. P. Dayer, J. Desmeules, and L. Collart Pharmacology of tramadol Drugs 53 suppl 2 1997 18 24
39. S.M. Rao, B. Netke, and T. Ponavala Post-operative pain relief by PCA vs. oral tramadol in cardiac surgery Ann Card Anaesth 4 2001 13 16
40. A.K. But, F. Erdil, and A. Yucel The effects of single-dose tramadol on post-operative pain and morphine requirements after coronary artery bypass surgery Acta Anaesthesiol Scand 51 2007 601 606
41. S. Goldstein, D. Dean, and S.J. Kim A survey of spinal and epidural techniques in adult cardiac surgery J Cardiothorac Vasc Anesth 15 2001 158 168
42. S.S. Liu, B.M. Block, and C.L. Wu Effects of perioperative central neuraxial analgesia on outcome after coronary artery bypass surgery: A meta-analysis Anesthesiology 101 2004 153 161
43. N. El Baz, and M. Goldin Continuous epidural infusion of morphine for pain relief after cardiac operations J Thorac Cardiovasc Surg 93 1987 878 883
44. T.H. Liem, M.A. Hasenbos, and L.H. Booij Coronary artery bypass grafting using two different anesthetic techniques: II Postoperative outcome J Cardiothorac Vasc Anesth 6 1992 156 161
45. H.M. Loick, C. Schmidt, and H. Van Aken High thoracic epidural anesthesia, but not clonidine, attenuates the perioperative stress response via sympatholysis and reduces the release of torponin T in patients undergoing coronary artery bypass grafting Anesth Analg 88 1999 701 709
46. A. Tenling, P.O. Joachimsson, and H. Tydén Thoracic epidural anesthesia as an adjunct to general anesthesia for cardiac surgery: Effects on ventilation-perfusion relationships J Cardiothorac Vasc Anesth 13 1999 258 264
47. S. Dohle, Y. Mehta, and H. Saxena Comparison of continuous thoracic epidural and paravertebral blocks for postoperative analgesia after minimally invasive direct coronary artery bypass surgery J Cardiothorac Vasc Anesth 15 2001 279 281
48. N.B. Scott, D.J. Turfey, and D.A. Ray A randomized study of the potential benefits of thoracic epidural anesthesia and analgesia in patients undergoing coronary artery bypass grafting Anesth Analg 93 2001 528 535
49. M.P. Fillinger, M.P. Yeager, and T.M. Dodds Epidural anesthesia and analgesia: Effects on recovery from cardiac surgery J Cardiothorac Vasc Anesth 16 2002 15 20
50. M.C. Priestly, L. Cope, and R. Halliwell Thoracic epidural anesthesia for cardiac surgery: The effects of tracheal intubation time and length of hospital stay Anesth Analg 94 2002 275 282
51. C. Royse, A. Royse, and P. Soeding Prospective randomized trial of high thoracic epidural analgesia for coronary artery bypass surgery Ann Thorac Surg 75 2003 93 100
52. M.J. Barrington, R. Kluger, and R. Watson Epidural anesthesia for coronary artery bypass surgery compared with general anesthesia alone does not reduce biochemical markers of myocardial damage Anesth Analg 100 2005 921 928
53. V. Hansdottir, J. Phillip, and M.F. Olsen Thoracic epidural versus intravenous patient-controlled analgesia after cardiac surgery Anesthesiology 104 2006 142 151
54. P.K. Tenenbein, R. Debrouwere, and D. Maguire Thoracic epidural analgesia improves pulmonary function in patients undergoing cardiac surgery Can J Anaesth 55 2008 344 350
55. Y. Mehta, V. Mayank, and S. Munish Thoracic epidural analgesia for off-pump coronary artery bypass surgery in patients with chronic obstructive pulmonary disease Ann Card Anaesth 13 2010 224 230
56. 2 for off pump coronary artery bypass surgery Ann Card Anaesth 13 2010 28 33
57. R. Stenseth, L. Bjella, and E.M. Berg Thoracic epidural analgesia in aortocoronary bypass surgery: Effects on the endocrine metabolic response Acta Anaesthesiol Scand 38 1994 834 839
58. C.M. Moore, M.H. Cross, and J.P. Desborough Hormonal effects of thoracic extradural analgesia for cardiac surgery Br J Aneaesth 9 1995 503 509
59. C. Royse, C. Remedios, and A. Royse High thoracic epidural analgesia reduces the risk of long-term depression in patients undergoing coronary artery bypass surgery Ann Thorac Cardiovasc Surg 13 2007 32 35
60. S.C. Ho, C.F. Royse, and A.G. Royse Persistent pain after cardiac surgery: An audit of high thoracic epidural and primary opioid analgesic therapies Anesth Analg 95 2002 820 823
61. M.K. Jensen, and C. Andersen Can thoracic poststernotomy pain after cardiac valve replacement be reduced using thoracic epidural analgesia? Acta Anaesthesiol Scand 48 2004 871 874
62. M.A. Chaney Thoracic epidural anaesthesia in cardiac surgery-the current standing Ann Card Anaesth 12 2009 1 3
63. C.F. Royse High thoracic epidural analgesia for cardiac surgery: Time to move from morbidity to quality of recovery indicators Ann Card Anaesth 12 2009 166 167
64. D. Bracco, and T. Hemmerling Epidural analgesia in cardiac surgery: An updated risk assessment Heart Surg Forum 10 2007 E334 E337
65. G. Fannelli, A. Casati, and M. Benti Incidence of hypotension and bradycardia during integrated epidural/general anesthesia An epidemiologic observational study of 1200 consecutive patients. Italian study group on integrated anaesthesia Minerva Anestesiol 64 1998 313 319
66. J.K. Wang, L.A. Nauss, and J.E. Thomas Pain relief by intrathecally applied morphine in man Anesthesiology 50 1979 149 151
67. A. Hindle Intrathecal opioid in the management of acute postoperative pain Contin Educ Anaesth Crit Care Pain 8 2008 81 85
68. H.E. McQuay, A.F. Sullivan, and H. Small Intrathecal opioids, potency, and lipophilicity Pain 36 1989 111 115
69. C. Aun, D. Thomas, and L. St. John-Jones Intrathecal morphine in cardiac surgery Eur J Anaesthesiol 2 1985 419 426
70. W.F. Casey, J.E. Wynands, and F.E. Ralley The role of intrathecal morphine in the anesthetic management of patients undergoing coronary artery bypass surgery J Cardiothorac Anesth 1 1987 510 516
71. G.S. Vanstrum, K.M. Bjornson, and R. Ilko Postoperative effects of intrathecal morphine in coronary artery bpass surgery Anesth Analg 67 1988 261 267
72. G.J. Fitzpatrick, and D.C. Moriarty Moriarty: Intrathecal morphine in the management of pain following cardiac surgery A comparison with IV morphine Br J Anaesth 60 1988 639 644
73. M.A. Chaney, K.R. Smith, and J.C. Barclay Large-dose intrathecal morphine for coronary artery bypass grafting Anesth Analg 83 1996 215 222
74. M.A. Chaney, P.A. Furry, and E.M. Fluder Intrathecal morphine for coronary artery bypass grafting and early extubation Anesth Analg 85 1997 706 707
75. M.A. Chaney, M.P. Nikolov, and B.P. Blakeman Intrathecal morphine for coronary artery bypass graft procedure and early extubation revisited J Cardiothorac Vasc Anesth 13 1999 574 578
76. E. Zarate, P. Latham, and P.F. White Fast-track cardiac anesthesia: Use of remifentanil combined with intrathecal morphine as an alternative to sufentanil during desflurane anesthesia Anesth Analg 91 2000 283 287
77. P. Latham, E. Zarate, and P.F. White Fast-track cardiac anesthesia: A comparison of remifentanil plus intrathecal morphine with sufentanil in a desflurane-based anesthetic J Cardiothorac Vasc Anesth 14 2000 645 651
78. J.A. Allhashemi, M.D. Sharpe, and C.L. Harris Effect of subarachnoid morphine administration on extubation after coronary artery bypass graft surgery J Cardiothorac Vasc Anesth 16 2002 132 134
79. A. Boulanger, S. Perreault, and M. Choiniere Intrathecal morphine after cardiac surgery Ann Pharm 36 2002 1337 1343
80. T. Lenkutis, A. Bieliunas, and I. Gedminaite Intrathecal morphine for postoperative analgesia in cardiac surgery Medicina (Kaunas) 38 suppl 2 2002 221 223
81. P. Lena, N. Balarac, and J.J. Arnulf Intrathecal morphine and clonidine for coronary artery bypass grafting Br J Anaesth 90 2003 300 303
82. Y. Mehta, V. Kukarni, and R. Juneia Spinal (subarachnoid) morphine for off-pump coronary artery bypass surgery Heart Surg Forum 7 2004 E205 E210
83. P. Lena, N. Balarac, and J.J. Arnulf Fast-track coronary artery bypass grafting surgery under general anesthesia with remifentanil and spinal analgesia with morphine and clonidine J Cardiothorac Vasc Anesth 19 2005 49 53
84. G. Turker, S. Goren, and S. Sahin Combination of intrathecal morphine and remifentanil infusion for fast-track anesthesia in off-pump coronary artery bypass surgery J Cardiothorac Vasc Anesth 19 2005 708 713
85. E. Jacobsohn, T.W.R. Lee, and R.J. Amadeo Low-Dose intrathecal morphine does not delay early extubation after cardiac surgery Can J Anaesth 52 2005 848 857
86. L. Roediger, J. Joris, and M. Senard The Use of pre-operative intrathecal morphine for analgesia following coronary artery bypass surgery J Anesth 61 2006 838 844
87. P. Lena, N. Balarac, and D. Lena Fast-track anesthesia with remifentanil and spinal analgesia for cardiac surgery: The effect on pain control and quality of recovery J Cardiothorac Vasc Anesth 22 2008 536 542
88. N.D. Nader, C.M. Li, and H.H. Dosluoglu Adjuvant therapy with intrathecal clonidine improves postoperative pain in patients undergoing coronary artery bypass graft Clin J Pain 25 2009 101 106
89. L.M. Dos Santos, V.C. Jorge Santos, and S.R.C. Jorge Santos Intrathecal morphine plus general anesthesia in cardiac surgery: Effects on pulmonary function, post-operative analgesia, and plasma morphine concentration Clinics (Sao Paolo) 64 2009 279 285
90. R. Xiulu Drug-related side effects of long-term intrathecal morphine therapy Pain Physician 10 2007 357 365
91. A.M. Barr, E. Tutungi, and A.A. Almeida Parasternal intercostal block with ropivacaine for pain management after cardiac surgery: A double-blind, randomized controlled trial J Cardiothorac Vasc Anesth 21 2007 547 553
92. S. Kocabas, D. Yedicocuklu, and E. Yuksel Infiltration of the sternotomy wound and the mediastinal tube sites with 0.25% levobupivicaine as adjunctive treatment for postoperative pain after cardiac surgery Eur J Anaesthesiol 25 2008 842 849
93. I. Koukis, M. Argiriou, and A. Dimakopoulou Use of continuous subcutaneous anesthetic infusion in cardiac surgical patients after median sternotomy J Cardiothorac Surg 3 2008 2
94. P.F. White, S. Rawal, and P. Latham Use of a continuous local anesthetic infusion for pain management after median sternotomy Anesthesiology 99 2003 918 923
95. S.B. McDonald, E. Jacobsohn, and D.J. Kopacz Parasternal block and local anesthetic infiltration with levobupivicaine after cardiac surgery with desflurane: The effect on postoperative pain, pulmonary function, and tracheal extubation times Anesth Analg 100 2005 25 32
96. R. Dowling, K. Thielmeier, and A. Ghaly Improved pain control after cardiac surgery: Results of a randomized double-blind, clinical trial J Thorac Cardiovasc Surg 126 2003 1271 1278
97. D. Mangano, R. Montalbano, and M. Lamarra Ineffectiveness of local wound anesthesia to reduce postoperative pain after median sternotomy J Cardiovasc Surg 20 2005 314 318
98. J. Richardson, P.A. Lönnqvist, and Z. Naja Bilateral thoracic paravertebral block: Potential and practice Br J Anaesth 106 2011 164 171
99. M. Canto, M.J. Sanchez, and M.A. Casas Bilateral paravertebral blockade for conventional cardiac surgery J Anesth 58 2003 365 370
100. I. Cattabriga, D. Pacini, and G. Lamazza Intravenous paracetamol as adjunctive treatment for postoperative pain after cardiac surgery: A double blind randomized controlled trial Eur J Cardiothorac Surg 32 2007 527 531
101. P. Lahtinen, H. Kokki, and H. Hendolin Propacetamol as adjunctive treatment for postoperative pain after cardiac surgery Anesth Analg 95 2002 813 819
102. M.K. Fayaz, R.J. Abel, and S.C. Pugh Opioid sparing effects of diclofenac and paracetamol lead to improved outcomes after cardiac surgery J Cardiothorac Vasc Anesth 18 2004 742 747
103. E. Ott, N.A. Nussmeier, and P.C. Duke Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery J Thorac Cardiovasc Surg 125 2003 1481 1492
104. N.A. Nussmeier, A.A. Whelton, and M.T. Brown Complications of COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery N Engl J Med 352 2005 1081 1091
105. A.M. Schjerning Olsen, E.L. Fosbel, and J. Lindhardsen Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction Circulation 123 2011 2226 2235
106. J. Hendrich, A.T. Van Minh, and F. Heblich Pharmacological disruption of calcium channel trafficking by the alpha2 delta ligand gabapentin Proc Natl Acad Sci U S A 105 2008 3628 3633
107. A. Ucak, B. Onan, and H. Sen The effects of gabapentin on acute and chronic post-operative pain after coronary artery bypass grafting J Cardiothorac Vasc Anesth 2011 Jan 11 (Epub ahead of print)
108. F. Menda, O. Köner, and M. Sayn Effects of a single dose of gabapentin on postoperative pain and morphine consumption after cardiac surgery J Cardiothorac Vasc Anesth 24 2010 808 813
109. I.L. Rapchuk, L. O'Connell, and C.D. Liessmann Effect of gabapentin on pain after cardiac surgery: A randomized controlled trial Anaesthesiol Intensive Care 38 2010 445 451
110. P. Lahtinen, H. Kokki, and T. Hakala S+ ketamine as an analgesic adjunct reduces opioid consumption after cardiac surgery Anesth Analg 99 2004 1295 1301
111. B. Steinlechner, M. Dworschak, and B. Birkenberg Magnesium moderately decreases remifentanil dosage required for pain management after cardiac surgery Br J Anaesth 96 2006 444 449
112. M. Emmiler, O. Solak, and C. Kocogullari Control of postoperative pain by transcutaneous electrical nerve stimulation after open cardiac operations: A randomized placebo controlled prospective study Heart Surg Forum 11 2008 300 303
113. G. Cipriano, A.C. Camargo Carvalho, and G.F. Franca Bernardelli Short-term transcutaneous electrical nerve stimulation after cardiac surgery: Effect on pain, pulmonary function, and electrical muscle activity Interact Cardiovasc Thorac Surg 7 2008 539 543
114. O. Solak, M. Emmiler, and Y. Ela Comparison of continuous and intermittent transcutaneous electrical nerve stimulation in postoperative pain management after coronary artery bypass grafting: A randomized-placebo- controlled prospective study Heart Surg Forum 12 2009 266 271
115. J. Watt-Watson, B. Stevens, and J. Costello Impact of education on pain management outcomes after coronary artery bypass graft surgery: A pilot Can J Nurs Res 31 2000 41 56
116. M. Diby, J.A. Romand, and S. Frick Reducing pain in patients undergoing cardiac surgery after implementation of a quality improvement postoperative pain treatment program J Crit Care 23 2008 359 371
117. L. Van Gulik, S.J. Ahlers, and Z. Brki Improved analgesia after the realization of a pain management programme in ICU patients after cardiac surgery Eur J Anaesthesiol 27 2010 900 905
118. C. Pasero, K. Puntillo, and D. Li Structured approaches to pain management in the ICU Chest 135 2009 1665 1672
119. W. Pongratz, W. Linke, and M. Baum Electroacupuncture analgesia in 500 heart surgery cases Anæsthesiol Intensivmed Prax 13 1977 19 33
120. M.C. Colak, A. Kavakli, and A. Kilinc Postoperative pain and respiratory function in patients treated with electroacupuncture following coronary surgery Neruosciences (Rivadh) 15 2010 7 10
121. M.A. Moustafa, A.A. Abdelsamad, and G. Zakaria Minimal vs. median sternotomy for aortic valve repair Asian Cardiovasc Thorac Ann 15 2007 472 475
122. S. Candaele, P. Herijgers, and R. Demevere Chest pain after partial upper versus complete sternotomy for aortic valve surgery Acta Cardiol 58 2003 17 21
123. M. Bauer, M. Pasic, and R. Ewert Ministernotomy versus complete sternotomy for coronary artery bypass operations: No difference in postoperative pulmonary function J Thorac Cardiovasc Surg 121 2001 702 707
124. A. Aris, M.L. Cámara, and J. Montiel Ministernotomy versus median sternotomy for aortic valve replacement: A prospective, randomized study Ann Thorac Surg 67 1999 1583 1587
125. L.G. Svensson, F.A. Atik, and D.M. Cosgrove Minimally invasive versus conventional mitral valve surgery: A propensity matched comparison J Thorac Cardiovasc Surg 139 2010 926 932
126. J. Bucerius, S. Metz, and T. Walther Endoscopic internal thoracic artery dissection leads to significant reduction of pain after minimally invasive direct coronary artery bypass surgery Ann Thorac Surg 73 2002 1180 1184
127. Diegeler A, Walther T, Metz S, et al. Comparison of midcab versus conventional CABG surgery regarding pain and quality of life. Heart Surg Forum 2:290-295, 199
128. G. Bolotin, G.D. Buckner, and Campbell Tissue-disruptive forces during median sternotomy Heart Surg Forum 10 2007 487 492
129. X.M. Mueller, F. Tinguely, and H.T. Tevaearai Impact of chest tube drainage on pain after cardiac surgery Eur J Cardiothorac Surg 18 2000 570 574
130. A.U. Gullu, A. Ekinci, and Y. Sensoz Preserved pleural integrity provides better respiratory function and pain score after coronary surgery J Cardiovasc Surg 24 2009 374 378
131. J. Meyerson, S. Thelin, and T. Gordh The incidence of chronic post-sternotomy pain after cardiac surgery-a prospective study Acta Anaesthesiol Scand 45 2001 940 944
132. J. Bruce, N. Drury, and A.S. Poobalan The prevalence of chronic chest and leg pain following cardiac surgery: A historical cohort study Pain 104 2003 265 273
133. C. Carle, A. Ashworth, and A. Roscoe A survey of post-sternotomy chronic pain following cardiac surgery J Anesth 64 2009 1387 1389
134. E. Kalso, S. Mennander, and T. Tasmuth Chronic post-sternotomy pain Acta Anaesthesiol Scand 45 2001 935 939
135. S.C. Ho, C.F. Royse, and A.G. Royse Persistent pain after cardiac surgery: An audit of high thoracic epidural and primary opioid analgesia therapies Anesth Analg 95 2002 820 823
136. K.M. King, M. Parry, and D. Southern Women's recovery from sternotomy-extension (WREST-E) study: Examining long-term pain and discomfort following sternotomy and their predictors Heart 94 2008 493 497
137. K.H. Gjeilo, P. Klepstad, and A. Wahba Chronic pain after cardiac surgery: A prospective study Acta Anaesthesiol Scand 54 2010 70 78
138. E. Eisenberg, Y. Pultorak, and D. Pud Prevalence and characteristics of post coronary artery bypass graft surgery pain (PCP) Pain 92 2001 11 17
139. M.C. Taillefer, M. Carrier, and S. Bélisle Prevalence, characteristics, and predictors of chronic nonanginal postoperative pain after a cardiac operation: A cross-sectional study J Thorac Cardiovasc Surg 131 2006 1274 1280
140. L. van Gulik, L.I. Janssen, and S.J.G.M. Ahlers Risk Factors for chronic thoracic pain after cardiac surgery via median sternotomy Eur J Cardiothorac Surg 2011 May 9 (Epub ahead of print)
141. A. Mailis, J. Chan, and A. Basinski Chest wall pain after aortocoronary bypass surgery using internal mammary artery graft: A new pain syndrome? Heart Lung 18 1989 553 558
142. N. Luleci, K. Dere, and M. Akbas Myofascial pain in post-sternotomy patients after cardiac surgery: A clinical study of 1226 patients J Back Musculoskel Rehab 21 2008 239 243
143. P.G. Fine, and S.V. Karwande Sternal wire-induced persistent chest pain: A possible hypersensitity reaction Ann Thorac Surg 49 1990 135 136
144. P.D. Wall, and M. Gutnick Properties of afferent nerve impulses originating from a neuroma Nature 248 1974 740 743
145. M. Devor Neuropathic pain: What do we do with all these theories? Acta Anaesthesiol Scand 45 2001 1121 1127
146. I. Gilron, P.N. Watson, and C.M. Cahill Neuropathic pain: A practical guide for the clinician CMAJ 175 2006 265 275
147. G. Baranauskas, and A. Nistri Sensitization of pain pathways in the spinal cord: Cellular mechanisms Prog Neurobiol 54 1998 349 365
148. M.O. Urban, and G.F. Gebhart The glutamate synapse: A target in the pharmacological management of hyperalgesic pain states Prog Brain Res 116 1998 407 420
149. J. Harris, C. Joules, and C. Stanley Glutamate and tachykinin receptor in central sensitization of withdrawal reflexes in the decerebrated rat Exp Physiol 89 2004 187 198
150. G.J. Bennett Update on the neurophysiology of pain transmission and modulation: Focus on the NMDA-receptor J Pain Symtom Manage 19 suppl 1 2000 S2 S6
151. S.T. Meller, and G.F. Gebhart Nitric oxide (NO) and nociceptive processing in the spinal cord Pain 52 1993 127 136
152. Z.D. Luo, and D. Cizkova The role of nitric oxide in nociception Curr Rev Pain 4 2000 459 466
153. A. Gottschalk, and S.N. Raja Severing the link between acute and chronic pain: The anesthesiologist's role in preventive medicine Anesthesiology 101 2004 1063 1065
154. T.J. Brennan, and H. Kehlet Preventive analgesia to reduce wound hyperalgesia and persistent postsurgical pain: Not an easy path Anesthesiology 103 2005 681 683
155. S.S. Reuben Preventing the development of complex regional pain syndrome after surgery Anesthesiology 101 2004 1215 1224
156. P. Lavand'homme, M. De Kock, and H. Waterloos Intraoperative epidural analgesia combined with ketamine provides effective preventive analgesia in patients undergoing major digestive surgery Anesthesiology 103 2005 813 820
157. A. Stubhaug, H. Breivik, and P.K. Eide Mapping of punctate hyperalgesia around a surgical inicision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery Acta Anaesthesiol Scand 41 1997 1124 1132
158. J. Katz, L. Cohen, and R. Schmid Postoperative morphine use and hyperalgesia are reduced by preoperative but not intraoperative epidural analgesia Implications for preemptive analgesia and the prevention of central sensitization Anesthesiology 98 2003 1214 1222
159. A.M. Duarte, E. Pospisilova, and E. Reilly Reduction of postincisional allodynia by subcutaneous bupivacaine: Findings with a new model in the hairy skin of the rat Anesthesiology 103 2005 113 125
160. A. Fassoulaki, K. Patris, and C. Sarantopoulos The analgesic effect of gabapentin and mexiletine after breast surgery for cancer Anesth Analg 95 2002 985 991
161. T.J. Coderre, and J. Katz Peripheral and central hyperexcitability: Differential signs and symptoms in persistent pain Behav Brain Sci 20 1997 404 419
162. S. Møiniche, H. Kehlet, and J.B. Dahl A qualitative and quantitative systematic review of preemptive analgesia for postoperative pain relief The role of timing of analgesia Anesthesiology 96 2002 725 741
163. C.K.S. Ong, P. Lirk, and R.A. Seymour The efficacy of preemptive analgesia for acute postoperative pain management: A meta-analysis Anesth Analg 100 2005 757 773
164. M.K. Jensen, and C. Andersen Can chronic poststernotomy pain after cardiac valve replacement be reduced using thoracic epidural analgesia? Acta Anaesthesiol Scand 48 2004 871 874
165. S.C. Ho, C.F. Royse, and A.G. Royse Persistent pain after cardiac surgery: An audit of high thoracic epidural and primary opioid analgesia therapies Anesth Analg 95 2002 820 823
166. I. Biyik, M. Glcler, and M. Karabiga Efficacy of gabapentin versus diclofenac in the treatment of chest pain and paresthesia in patients with sternotomy Anadolu Kardiyol Derg 9 2009 390 396
167. G.N. Goyal, D. Gupta, and R. Jain Peripheral nerve field stimulation for intractable post-thoracotomy scar pain not relieved by conventional treatment Pain Pract 10 2010 366 369
168. R. Chou, G.J. Fanciullo, and P.G. Fine Clinical Guidelines for use of opioid therapy in chronic noncancer pain J Pain 10 2009 113 130
169. K. Manchikanti Effectiveness of long term opioid therapy for chronic noncancer pain Pain Physician 14 2011 133 156
170. K. Doi, T. Nikai, and S. Sakura Intercostal nerve blocks with 5% tetracaine for chronic pain syndromes J Clin Anesth 14 2002 39 41
171. S.P. Cohen, A. Sireci, and C.L. Wu Pulsed radio frequency of the dorsal root ganglia is superior to pharmacotherapy or pulsed radio frequency of the intercostal nerves in the treatment of chronic postsurgical thoracic pain Pain Physician 9 2006 227 236
172. L. Manchikanti, K.A. Cash, and C.D. McManus A preliminary report of a randomized double blind active controlled trial of fluoroscopic interlaminar epidural injections in managing chronic thoracic pain Pain Physician 13 2010 357 369
173. R.H. Dworkin, A.B. O'Connor, and J. Audette Recommendations for the pharmacologic management of neuropathic pain: An overview and literature update Mayo Clin Proc 85 2010 S3 S14
174. O.A. de Leon-Casasola Spinal cord and peripheral nerve stimulation techniques for neuropathic pain J Pain Symptom Manage 38 2009 S28 S38
175. T. Goroszeniuk, D. Pang, and A. Al-Kaisy Subcutaneous target stimulationPeripheral subcutaneous field stimulation in the treatment of refractory angina: Preliminary case reports Pain Practice 11 2011 1 9