Intravenous paracetamol as adjunctive treatment for postoperative pain after cardiac surgery: a double blind randomized controlled trial

European Journal of Cardio-thoracic Surgery

Volumn 32, Issue 3, 2007, Pages 527-531

  Cattabriga, Iolter ^a   Pacini, Davide ^a   Lamazza, Gaia ^a   Talarico, Francesco ^a   Di Bartolomeo, Roberto ^a   Grillone, Giovanni ^a   Bacchi Reggiani, Letizia ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Analgesia; Cardiac surgery; Postoperative pain

Indexed keywords

MORPHINE; ONDANSETRON; PARACETAMOL; PLACEBO; TRAMADOL;

ADULT; AGED; ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HEART SURGERY; HUMAN; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; TREATMENT RESPONSE; VOMITING;

ACETAMINOPHEN; AGED; ANALGESICS, NON-NARCOTIC; ANALGESICS, OPIOID; CARDIAC SURGICAL PROCEDURES; CHEMOTHERAPY, ADJUVANT; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; POSTOPERATIVE NAUSEA AND VOMITING; TRAMADOL;

EID: 34547666747     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcts.2007.05.017     Document Type: Article

References (20)

1. Mueller X.M., Tinguely F., Tevaeaeri H.T., Revelly J.P., Chiolero R., and von Segesser L.K. Pain location, distribution, and intensity after cardiac surgery. Chest 118 (2000) 391-396
2. Mangano D.T., Siciliano D., Hollenberg M., Leung J.M., Browner W.S., Goehner P., Merrick S., and Verrier E. Postoperative myocardial ischemia. Therapeutic trials using intensive analgesia following surgery. The Study of Perioperative Ischemia (SPI) Research Group. Anesthesiology 76 3 (1992) 342-353
3. Craig D.B. Postoperative recovery of pulmonary function. Anesth Analg 60 1 (1981) 46-52
4. Tuman K.J., McCarthy R.J., March R.J., DeLaria G.A., Patel R.V., and Ivankovich A.D. Effects of epidural anesthesia and analgesia on coagulation and outcome after major vascular surgery. Anesth Analg 73 6 (1991) 696-704
5. Gust R., Pecher S., Gust A., Hoffmann V., Bohrer H., and Martin E. Effect of patient-controlled analgesia of pulmonary complications after coronary artery bypass grafting. Crit Care Med 27 (1999) 221-223
6. Lahtinen P., Kokki H., Hendolin H., Hakala T., and Hynynen M. Propacetamol as adjunctive treatment for postoperative pain after cardiac surgery. Anesth Analg 95 (2002) 813-819
7. Garcia Rodriguez R.L., and Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 343 (1994) 769-772
8. Petterson P.H., Jakobsson J., and Owall A. Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting. J Cardiothorac Vasc Anesth 19 3 (2005) 306-309
9. Petterson P.H., Jakobsson J., and Owall A. Plasma concentrations following repeated rectal or intravenous administration of paracetamol after heart surgery. Acta Anaesthesiol Scand 50 (2006) 673-677
10. Ranucci M., Cazzaniga A., Soro G., Isgro G., Rossi R., and Pavesi M. Postoperative analgesia for early extubation after cardiac surgery. A prospective, randomized trial. Minerva Anestesiol 65 (1999) 859-865
11. Chu Y.C., Lin S.M., Hsieh Y.C., Chan K.H., and Tsou M.Y. Intraoperative administration of tramadol for postoperative nurse-controlled analgesia resulted in earlier awakening and less sedation than morphine in children after cardiac surgery. Anesth Analg 102 (2006) 1668-1673
12. Barilaro C., Rossi M., Martinelli L., Guarneri S., Cimino A., and Schiavello R. Control of postoperative pain in cardiac surgery: comparison of analgesics. Minerva Anestesiol 67 (2001) 171-179
13. Marcou T.A., Marque S., Mazoit J.X., and Benhamou D. The median effective dose of tramadol and morphine for postoperative patients: a study of interactions. Anesth Analg 100 (2005) 469-474
14. Kehlet H., Werner M., and Perkins F. Balanced analgesia: what is it and what are its advantages in postoperative pain?. Drugs 58 (1999) 793-797
15. Practices guidelines for acute pain management in the perioperative setting. A report by the American Society of Anesthesiologists Task Force of Pain Management, Acute Pain section. Anesthesiology 1995; 82(4):1071-81, amended October 15, 2003.
16. Dahl J.B., Rosenberg J., Dirkes W.E., Mogensen T., and Kehlet H. Prevention of postoperative pain by balanced analgesia. Br J Anaesth 64 (1990) 518-520
17. Kehlet H., and Dahl J.B. The value of "multimodal" or "balanced analgesia" in postoperative pain treatment. Anesth Analg 77 (1993) 1048-1056
18. Flouvat B., Leneveu A., Fitoussi S., Delhotal-Landes B., and Gendron A. Bioequivalence study comparing a new paracetamol solution for injection and propacetamol after single intravenous infusion in healthy subjects. Int J Clin Pharmacol Ther 42 1 (2004) 50-57
19. Hynes D., McCarrol M., and Hiesse-Provost O. Analgesic efficacy of parenteral paracetamol (propacetamol) and diclofenac in post-operative orthopedic pain. Acta Anaesthesiol Scand 50 (2006) 374-381
20. Aouad M.T., Siddik-Sayyid S.M., Taha S.K., Azar M.S., Nasr V.G., Hakki M.A., Zoorob D.G., and Baraka A.S. Haloperidol vs ondansetron for the prevention of postoperative nausea and vomiting following gynaecological surgery. Eur J Anaesthesiol (2006) 1-8