Cellular photodynamic toxicity of hematoporphyrin in various nanocarrier systems

Current Nanoscience

Volumn 7, Issue 6, 2011, Pages 850-855

  Yang, Yu Tsai ^a   Chen, Chin Tin ^b   Chien, Hsiung Fei ^c   Tsai, Tsuimin ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Liposomes; Micelles; Nanoparticles; Photodynamic therapy; Photosensitizers; Protein binding

Indexed keywords

A549 CELLS; CELLULAR UPTAKE; EXTRUSION METHOD; FLUORESCENCE SPECTROMETRY; HEMATOPORPHYRIN; HUMAN LUNG; HYDRATION METHOD; LASER LIGHT SCATTERING; NANOCARRIERS; PHOTOCYTOTOXICITY; PROTEIN BINDING; SERUM PROTEINS; SERUM-FREE MEDIUM; TOXIC EFFECT;

BIOCHEMISTRY; BIOLOGICAL ORGANS; BODY FLUIDS; CELLS; EMULSIFICATION; FILM PREPARATION; FLUORESCENCE SPECTROSCOPY; HYDRATION; LIGHT SCATTERING; LIPOSOMES; MICELLES; NANOPARTICLES; PHOSPHOLIPIDS; PHOTODYNAMIC THERAPY; PHOTOSENSITIZERS; PORPHYRINS; RESPIRATORY SYSTEM; TOXICITY; ZETA POTENTIAL;

LIGHT EMITTING DIODES;

HEMATOPORPHYRIN; LIPOSOME; NANOCARRIER; PLASMA PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL TRANSPORT; CONTROLLED STUDY; CULTURE MEDIUM; DIFFUSION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG UPTAKE; EMULSION; HUMAN; HUMAN CELL; HYDRATION; LIGHT EMITTING DIODE; LIGHT SCATTERING; LIPOSOMAL DELIVERY; LUNG ADENOCARCINOMA; MICELLE; NANOENCAPSULATION; PARTICLE SIZE; PHOTOTOXICITY; PRIORITY JOURNAL; SLOW DRUG RELEASE; SPECTROFLUOROMETRY; SURFACE CHARGE; ZETA POTENTIAL;

EID: 82155170749     PISSN: 15734137     EISSN: 18756786     Source Type: Journal    
DOI: 10.2174/157341311798220718     Document Type: Article

References (33)

1. Ackroyd, R.; Kelty, C.; Brown, N.; Reed, M. The history of photodetection and photodynamic therapy. Photochem. Photobiol., 2001, 74(5), 656-669.
2. Ell, C.; Gossner, L.; May, A.; Schneider, H.T.; Hahn, E.G.; Stolte, M. Photodynamic ablation of early cancers of the stomach by means of mTHPC and laser irradiation: preliminary clinical experience. Gut., 1998, 43(3), 345-349.
3. Vrouenraets, M. B.; Visser, G. W.; Snow, G. B., van Dongen, G. A. Basic principles, applications in oncology and improved selectivity of photodynamic therapy. Anticancer Res., 2003, 23(1B), 505-522.
4. Serebrovskaya, E. O.; Edelweiss, E. F.; Stremovskiy, O. A.; Lukyanov, K. A.; Chudakov, D. M.; Deyev, S. M. Targeting cancer cells by using an antireceptor antibody-photosensitizer fusion protein. Proc. Natl. Acad. Sci., 2009, 106(23), 9221-9225.
5. Del Governatore, M.; Hamblin, M. R.; Shea, C. R.; Rizvi, I.; Molpus, K. G.; Tanabe, K. K. Experimental photoimmunotherapy of hepatic metastases of colorectal cancer with a 17.1A chlorin(e6) immunoconjugate. Cancer Res., 2000, 60(15), 4200-4205.
6. Tsai, T.; Yang, Y. T.; Wang, T. H.; Chien, H. F.; Chen, C. T. Improved photodynamic inactivation of gram-positive bacteria using hematoporphyrin encapsulated in liposomes and micelles. Lasers Surg. Med., 2009, 41(4), 316-322.
7. Fahmy, T.M.; Fong, P. M.; Park, J.; Constable, T.; Saltzman, W.M. Nanosystems for simultaneous imaging and drug delivery to T cells. AAPS. J., 2007, 9(2), 171-180.
8. Torchilin, V.P. Targeted pharmaceutical nanocarriers for cancer therapy and imaging. AAPS. J., 2007, 9(2), 128-147.
9. Jori, G. Factors controlling the selectivity and efficiency of tumour damage in photodynamic therapy. Lasers Med. Sci., 1990, 5, 115-120.
10. Igarashi, A.; Konno, H.; Tanaka, T.; Nakamura, S.; Sadzuka, Y.; Hirano, T. Liposomal photofrin enhances therapeutic efficacy of photodynamic therapy against the human gastric cancer. Toxicol. Lett., 2003, 145(2), 133-141.
11. Shieh, M. J.; Peng, C. L.; Chiang, W. L.; Wang, C. H.; Hsu, C. Y.; Wang, S. J. Reduced skin photosensitivity with meta-tetra(hydroxyphenyl)chlorinloaded micelles based on a poly(2-ethyl-2-oxazoline)-b-poly(d,l-lactide) diblock copolymer in vivo. Mol. Pharm., 2010, 7(4), 1244-1253.
12. Vargas, A.; Pegaz, B.; Debefve, E.; Konan-Kouakou, Y.; Lange, N.; Ballini, J.P. Improved photodynamic activity of porphyrin loaded into nanoparticles: an in vivo evaluation using chick embryos. Int. J. Pharm., 2004, 286(1-2), 131-145.
13. Kongshaug, M. Distribution of tetrapyrrole photosensitizers among human plasma proteins. Int. J. Biochem., 1992, 24, 1239-1265.
14. Konan, Y. N.; Chevallier, J.; Gurny, R.; Allemann, E. Encapsulation of p-THPP into nanoparticles: cellular uptake, subcellular localization and effect of serum on photodynamic activity. Photochem. Photobiol., 2003, 77(6), 638-644.
15. Yang, Y. T.; Chen, C. T.; Yang, J. C.; Tsai, T. Spray-dried microparticles containing polymeric micelles encapsulating hematoporphyrin. AAPS. J., 2010, 12, 138-146.
16. Konan, Y. N.; Berton, M.; Gurny, R.; Allemann, E. Enhanced photodynamic activity of meso-tetra(4-hydroxyphenyl)porphyrin by incorporation into sub200 nm nanoparticles. Eur. J. Pharm Sci., 2003, 18(3-4), 241-249.
17. Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods., 1983, 65, 55-63.
18. Konan, Y. N.; Gurny, R.; Allemann, E. State of the art in the delivery of photosensitizers for photodynamic therapy. J. Photochem. Photobiol. B., 2002, 66(2), 89-106.
19. Bourre, L.; Thibaut, S.; Fimiani, M.; Ferrand, Y.; Simonneaux, G.; Patrice, T. In vivo photosensitizing efficiency of a diphenylchlorin sensitizer: interest of a DMPC liposome formulation. Pharmacol. Res., 2003, 47(3), 253-261.
20. Jiang, F.; Lilge, L.; Grenier, J.; Li, Y.; Wilson, M. D.; Chopp, M. Photodynamic therapy of U87 human glioma in nude rat using liposome-delivered photofrin. Lasers Surg. Med., 1998, 22(2), 74-80.
21. van Nostrum, C. F. Polymeric micelles to deliver photosensitizers for photodynamic therapy. Adv. Drug. Deliv. Rev., 2004, 56(1), 9-16.
22. Zeisser-Labouebe, M.; Lange, N.; Gurny, R.; Delie, F. Hypericin-loadednanoparticles for the photodynamic treatment of ovarian cancer. Int. J. Pharm., 2006, 326(1-2), 174-181.
23. Panyam, J.; Sahoo, S. K.; Prabha, S.; Bargar, T.; Labhasetwar, V. Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(D,L-lactide-co-glycolide) nanoparticles. Int. J. Pharm., 2003, 262(1-2), 1-11.
24. Jung, T.; Kamm, W.; Breitenbach, A.; Kaiserling, E.; Xiao, J. X.; Kissel, T. Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake? Eur. J. Pharm. Biopharm., 2000, 50(1), 147-160.
25. Patil, S.; Sandberg, A.; Heckert, E.; Self, W.; Seal, S. Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential. Biomaterials, 2007, 28(31), 4600-4607.
26. Win, K. Y.; Feng, S. S. Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs. Biomaterials, 2005, 26(15), 2713-2722.
27. Rodal, G. H.; Rodal, S. K.; Moan, J.; Berg, K. Liposome-bound Zn (II)-phthalocyanine. Mechanisms for cellular uptake and photosensitization. J. Photochem. Photobiol. B., 1998, 45(2-3), 150-159.
28. Rezzoug, H.; Bezdetnaya, L.; A'amar, O.; Merlin, J. L.; Guillemin, F. Parameters affecting photodynamic activity of Foscan or metatetra(hydroxyphenyl)chlorin (mTHPC) in vitro and in vivo. Lasers Med. Sci., 1998, 13, 119-125.
29. Bourdon, O.; Mosqueira, V.; Legrand, P.; Blais, J. A comparative study of the cellular uptake, localization and phototoxicity of metatetra(hydroxyphenyl) chlorin encapsulated in surface-modified submicronic oil/water carriers in HT29 tumor cells. J. Photochem. Photobiol. B., 2000, 55(2-3), 164-171.
30. Jeon, S. I.; Lee, J. H.; Andrade, J. D.; De Gennes, P. G. Protein-surface interactions in the presence of polyethylene oxide. I. Simplified theory. J. Colloid. Interface. Sci., 1991, 142, 149-158.
31. Jones, M.; Leroux, J. Polymeric micelles a new generation of colloidal drug carriers. Eur. J. Pharm. Biopharm., 1999, 48(2), 101-111.
32. Qualls, M. M.; Thompson, D. H. Chloroaluminum phthalocyanine tetrasulfonate delivered via acid-labile diplasmenylcholine-folate liposomes: intracellular localization and synergistic phototoxicity. Int. J. Cancer., 2001, 93(3), 384-392.
33. Woodburn, K. W.; Vardaxis, N. J.; Hill, J. S.; Kaye, A. H.; Phillips, D. R. Subcellular localization of porphyrins using confocal laser scanning microscopy. Photochem. Photobiol., 1991, 54(5), 725-732.