Improved photodynamic activity of porphyrin loaded into nanoparticles: An in vivo evaluation using chick embryos

International Journal of Pharmaceutics

Volumn 286, Issue 1-2, 2004, Pages 131-145

  Vargas, Angelica ^a   Pegaz, Bernadette ^b   Debefve, Elodie ^b   Konan Kouakou, Yvette ^b   Lange, Norbert ^a   Ballini, Jean Pierre ^b   Van Den Bergh, Hubert ^b   Gurny, Robert ^a   Delie, Florence ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b EPFL   (Switzerland)

Author keywords

Biodegradable nanoparticles; Chick chorioallantoic membrane (CAM) model; Drug delivery system; Extravasation; Photodynamic therapy (PDT); Porphyrin (p THPP)

Indexed keywords

DRUG CARRIER; DRUG SOLVENT; NANOPARTICLE; PHOTOSENSITIZING AGENT; POLYGLACTIN; PORPHYRIN DERIVATIVE; RESOMER; TETRAKIS(4 HYDROXYPHENYL)PORPHYRIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BREAST TUMOR; CHICK EMBRYO; CHORIOALLANTOIS; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG TOLERABILITY; EMBRYO; ENCAPSULATION; EXPERIMENTAL MODEL; FLUORESCENCE; IN VIVO STUDY; IRRADIATION; LIGHT; MEMBRANE MODEL; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL;

ANIMALS; CHICK EMBRYO; CHICKENS; CHORIOALLANTOIC MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; ETHANOL; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; FLUORESCENCE; HYDROPHOBICITY; INJECTIONS; LACTIC ACID; NANOTECHNOLOGY; PARTICLE SIZE; PHARMACEUTICAL SOLUTIONS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; POLYGLYCOLIC ACID; POLYMERS; PORPHYRINS; SOLUBILITY; SWITZERLAND;

EID: 6944232702     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2004.07.029     Document Type: Article

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