메뉴 건너뛰기




Volumn 33, Issue 1, 2012, Pages 16-22

Repeated exposure of adult rats to Aroclor 1254 induces neuronal injury and impairs the neurochemical manifestations of the NMDA receptor-mediated intracellular signaling in the hippocampus

Author keywords

Cyclic GMP; Glutamate; Microdialysis; NMDA receptor; Polychlorinated biphenyls (PCBs); Rat hippocampus

Indexed keywords

ARGININE; AROCLOR 1254; ASPARTIC ACID; CALCIUM CHLORIDE; CYCLIC GMP; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITROGEN OXIDE; TAURINE;

EID: 82055191813     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2011.10.005     Document Type: Article
Times cited : (13)

References (47)
  • 1
    • 29144515343 scopus 로고    scopus 로고
    • Taurine interaction with neurotransmitter receptors in the CNS: an update
    • Albrecht J., Schousboe A. Taurine interaction with neurotransmitter receptors in the CNS: an update. Neurochem Res 2005, 30:1615-1621.
    • (2005) Neurochem Res , vol.30 , pp. 1615-1621
    • Albrecht, J.1    Schousboe, A.2
  • 2
    • 70349873426 scopus 로고    scopus 로고
    • Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription
    • Almeida L.E., Murray P.D., Zielke H.R., Roby C.D., Kingsbury T.J., Krueger B.K. Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription. J Neurosci 2009, 29:12702-12710.
    • (2009) J Neurosci , vol.29 , pp. 12702-12710
    • Almeida, L.E.1    Murray, P.D.2    Zielke, H.R.3    Roby, C.D.4    Kingsbury, T.J.5    Krueger, B.K.6
  • 3
    • 58149235281 scopus 로고    scopus 로고
    • Glutamine synthetase becomes nitrated and its activity is reduced during repetitive seizure activity in the pentylentetrazole model of epilepsy
    • Bidmon H.J., Görg B., Palomero-Gallagher N., Schleicher A., Häussinger D., Speckmann E.J., et al. Glutamine synthetase becomes nitrated and its activity is reduced during repetitive seizure activity in the pentylentetrazole model of epilepsy. Epilepsia 2008, 49:1733-1748.
    • (2008) Epilepsia , vol.49 , pp. 1733-1748
    • Bidmon, H.J.1    Görg, B.2    Palomero-Gallagher, N.3    Schleicher, A.4    Häussinger, D.5    Speckmann, E.J.6
  • 4
    • 78650416994 scopus 로고    scopus 로고
    • Differential long-term effects of developmental exposure to polychlorinated biphenyls 52, 138 or 180 on motor activity and neurotransmission, Gender dependence and mechanisms involved
    • Boix J., Cauli O., Leslie H., Felipo V. Differential long-term effects of developmental exposure to polychlorinated biphenyls 52, 138 or 180 on motor activity and neurotransmission, Gender dependence and mechanisms involved. Neurochem Int 2011, 58:69-77.
    • (2011) Neurochem Int , vol.58 , pp. 69-77
    • Boix, J.1    Cauli, O.2    Leslie, H.3    Felipo, V.4
  • 5
    • 0036905921 scopus 로고    scopus 로고
    • Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review
    • Butterfield D.A. Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review. Free Radic Res 2002, 36:1307-1313.
    • (2002) Free Radic Res , vol.36 , pp. 1307-1313
    • Butterfield, D.A.1
  • 6
    • 79956283252 scopus 로고    scopus 로고
    • Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis
    • Castegna A., Palmieri L., Spera I., Porcelli V., Palmieri F., Fabis-Pedrini M.J., et al. Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis. Neuroscience 2011, 185:97-105.
    • (2011) Neuroscience , vol.185 , pp. 97-105
    • Castegna, A.1    Palmieri, L.2    Spera, I.3    Porcelli, V.4    Palmieri, F.5    Fabis-Pedrini, M.J.6
  • 7
    • 4444334949 scopus 로고    scopus 로고
    • Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short- and long-term memory in 30-day-old Sprague-Dawley rats
    • Donahue D.A., Dougherty E.J., Meserve L.A. Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short- and long-term memory in 30-day-old Sprague-Dawley rats. Toxicology 2004, 15(203):99-107.
    • (2004) Toxicology , vol.15 , Issue.203 , pp. 99-107
    • Donahue, D.A.1    Dougherty, E.J.2    Meserve, L.A.3
  • 8
    • 12844262177 scopus 로고    scopus 로고
    • Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts
    • Erceg S., Monfort P., Hernandez-Viadel M., Rodrigo R., Montoliu C., Felipo V. Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts. Hepatology 2005, 41:299-306.
    • (2005) Hepatology , vol.41 , pp. 299-306
    • Erceg, S.1    Monfort, P.2    Hernandez-Viadel, M.3    Rodrigo, R.4    Montoliu, C.5    Felipo, V.6
  • 9
    • 33748603757 scopus 로고    scopus 로고
    • Alterations of oxidative stress biomarkers due to in utero and neonatal exposures of airborne manganese
    • Erikson K.M., Dorman D.C., Fitsanakis V., Lash L.H., Aschner M. Alterations of oxidative stress biomarkers due to in utero and neonatal exposures of airborne manganese. Biol Trace Elem Res 2006, 111:199-215.
    • (2006) Biol Trace Elem Res , vol.111 , pp. 199-215
    • Erikson, K.M.1    Dorman, D.C.2    Fitsanakis, V.3    Lash, L.H.4    Aschner, M.5
  • 11
    • 70450216122 scopus 로고    scopus 로고
    • Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants
    • Fonnum F., Mariussen E. Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants. J Neurochem 2009, 111:1327-1347.
    • (2009) J Neurochem , vol.111 , pp. 1327-1347
    • Fonnum, F.1    Mariussen, E.2
  • 12
    • 0032755594 scopus 로고    scopus 로고
    • Developmental exposure to a commercial PCB mixture (Aroclor 1254) produces a persistent impairment in long-term potentiation in the rat dentate gyrus in vivo
    • Gilbert M.E., Crofton K.M. Developmental exposure to a commercial PCB mixture (Aroclor 1254) produces a persistent impairment in long-term potentiation in the rat dentate gyrus in vivo. Brain Res 1999, 850:87-95.
    • (1999) Brain Res , vol.850 , pp. 87-95
    • Gilbert, M.E.1    Crofton, K.M.2
  • 13
    • 0031828908 scopus 로고    scopus 로고
    • Alterations in synaptic transmission and plasticity in hippocampus by a complex PCB mixture, Aroclor 1254
    • Gilbert M.E., Liang D. Alterations in synaptic transmission and plasticity in hippocampus by a complex PCB mixture, Aroclor 1254. Neurotoxicol Teratol 1998, 20:383-389.
    • (1998) Neurotoxicol Teratol , vol.20 , pp. 383-389
    • Gilbert, M.E.1    Liang, D.2
  • 15
    • 0033993867 scopus 로고    scopus 로고
    • Activation of N-methyl-d-aspartate receptors in rat brain in vivo following acute ammonia intoxication: characterization by in vivo brain microdialysis
    • Hermenegildo C., Monfort P., Felipo V. Activation of N-methyl-d-aspartate receptors in rat brain in vivo following acute ammonia intoxication: characterization by in vivo brain microdialysis. Hepatology 2000, 31:709-715.
    • (2000) Hepatology , vol.31 , pp. 709-715
    • Hermenegildo, C.1    Monfort, P.2    Felipo, V.3
  • 16
    • 0038066410 scopus 로고    scopus 로고
    • Taurine reduces ammonia- and N-methyl-d-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum
    • Hilgier W., Anderzhanova E., Oja S.S., Saransaari P., Albrecht J. Taurine reduces ammonia- and N-methyl-d-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum. Eur J Pharmacol 2003, 468:21-25.
    • (2003) Eur J Pharmacol , vol.468 , pp. 21-25
    • Hilgier, W.1    Anderzhanova, E.2    Oja, S.S.3    Saransaari, P.4    Albrecht, J.5
  • 17
    • 0344938208 scopus 로고    scopus 로고
    • Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure
    • Hilgier W., Zielińska M., Borkowska H.D., Gadamski R., Walski M., Oja S.S., et al. Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure. J Neurosci Res 1999, 56:76-84.
    • (1999) J Neurosci Res , vol.56 , pp. 76-84
    • Hilgier, W.1    Zielińska, M.2    Borkowska, H.D.3    Gadamski, R.4    Walski, M.5    Oja, S.S.6
  • 18
    • 0031881334 scopus 로고    scopus 로고
    • Halogenated aromatic hydrocarbons suppress CA1 field excitatory postsynaptic potentials in rat hippocampal slices
    • Hong S.J., Grover C.A., Safe S.H., Tiffany-Castiglioni E., Frye G.D. Halogenated aromatic hydrocarbons suppress CA1 field excitatory postsynaptic potentials in rat hippocampal slices. Toxicol Appl Pharmacol 1998, 148:7-13.
    • (1998) Toxicol Appl Pharmacol , vol.148 , pp. 7-13
    • Hong, S.J.1    Grover, C.A.2    Safe, S.H.3    Tiffany-Castiglioni, E.4    Frye, G.D.5
  • 19
    • 3142753605 scopus 로고    scopus 로고
    • Aroclor 1254 inhibits tryptophan hydroxylase activity in rat brain
    • Khan I.A., Thomas P. Aroclor 1254 inhibits tryptophan hydroxylase activity in rat brain. Arch Toxicol 2004, 78:316-320.
    • (2004) Arch Toxicol , vol.78 , pp. 316-320
    • Khan, I.A.1    Thomas, P.2
  • 20
    • 80855147547 scopus 로고    scopus 로고
    • Aroclor 1254, a developmental neurotoxicant, alters energy metabolism- and intracellular signaling-associated protein networks in rat cerebellum and hippocampus
    • Kodavanti P.R., Osorio C., Royland J.E., Ramabhadran R., Alzate O. Aroclor 1254, a developmental neurotoxicant, alters energy metabolism- and intracellular signaling-associated protein networks in rat cerebellum and hippocampus. Toxicol Appl Pharmacol 2011, 10.1016/j.taap.2011.07.005.
    • (2011) Toxicol Appl Pharmacol
    • Kodavanti, P.R.1    Osorio, C.2    Royland, J.E.3    Ramabhadran, R.4    Alzate, O.5
  • 21
    • 0031905889 scopus 로고    scopus 로고
    • N-methyl-d-aspartate receptor-mediated, calcium-induced calcium release in rat dentate gyrus/CA4 in vivo
    • Lazarewicz J.W, Rybkowski W., Sadowski M., Ziembowicz A., Alaraj M., Wegiel J., et al. N-methyl-d-aspartate receptor-mediated, calcium-induced calcium release in rat dentate gyrus/CA4 in vivo. J Neurosci Res 1998, 51:76-84.
    • (1998) J Neurosci Res , vol.51 , pp. 76-84
    • Lazarewicz, J.W.1    Rybkowski, W.2    Sadowski, M.3    Ziembowicz, A.4    Alaraj, M.5    Wegiel, J.6
  • 22
  • 23
    • 70449528743 scopus 로고    scopus 로고
    • Polychlorinated biphenyls PCB 153 and PCB 126 impair the glutamate-nitric oxide-cGMP pathway in cerebellar neurons in culture by different mechanisms
    • Llansola M., Piedrafita B., Rodrigo R., Montoliu C., Felipo V. Polychlorinated biphenyls PCB 153 and PCB 126 impair the glutamate-nitric oxide-cGMP pathway in cerebellar neurons in culture by different mechanisms. Neurotox Res 2009, 16:97-105.
    • (2009) Neurotox Res , vol.16 , pp. 97-105
    • Llansola, M.1    Piedrafita, B.2    Rodrigo, R.3    Montoliu, C.4    Felipo, V.5
  • 24
    • 36849072696 scopus 로고    scopus 로고
    • N-methyl-d-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus
    • Luccini E., Musante V., Neri E., Raiteri M., Pittaluga A. N-methyl-d-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus. J Neurosci Res 2007, 85:3657-3665.
    • (2007) J Neurosci Res , vol.85 , pp. 3657-3665
    • Luccini, E.1    Musante, V.2    Neri, E.3    Raiteri, M.4    Pittaluga, A.5
  • 25
    • 0346728801 scopus 로고    scopus 로고
    • Long-term potentiation and memory
    • Lynch M.A. Long-term potentiation and memory. Physiol Rev 2004, 84:87-136.
    • (2004) Physiol Rev , vol.84 , pp. 87-136
    • Lynch, M.A.1
  • 27
    • 0037087625 scopus 로고    scopus 로고
    • The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the N-methyl-d-aspartate receptor and reactive oxygen species
    • Mariussen E., Myhre O., Reistad T., Fonnum F. The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the N-methyl-d-aspartate receptor and reactive oxygen species. Toxicol Appl Pharmacol 2002, 179:137-144.
    • (2002) Toxicol Appl Pharmacol , vol.179 , pp. 137-144
    • Mariussen, E.1    Myhre, O.2    Reistad, T.3    Fonnum, F.4
  • 28
    • 1642456626 scopus 로고    scopus 로고
    • Hyperammonemia impairs long-term potentiation in hippocampus by altering the modulation of cGMP-degrading phosphodiesterase by protein kinase G
    • Monfort P., Muñoz M.D., Felipo V. Hyperammonemia impairs long-term potentiation in hippocampus by altering the modulation of cGMP-degrading phosphodiesterase by protein kinase G. Neurobiol Dis 2004, 15:1-10.
    • (2004) Neurobiol Dis , vol.15 , pp. 1-10
    • Monfort, P.1    Muñoz, M.D.2    Felipo, V.3
  • 29
    • 79954571300 scopus 로고    scopus 로고
    • Aspartate release and signalling in the hippocampus
    • Nadler J.V. Aspartate release and signalling in the hippocampus. Neurochem Res 2011, 36:668-676.
    • (2011) Neurochem Res , vol.36 , pp. 668-676
    • Nadler, J.V.1
  • 30
    • 0032080262 scopus 로고    scopus 로고
    • PCBs reduce long-term potentiation in the CA1 region of rat hippocampus
    • Niemi W.D., Audi J., Bush B., Carpenter D.O. PCBs reduce long-term potentiation in the CA1 region of rat hippocampus. Exp Neurol 1998, 151:26-34.
    • (1998) Exp Neurol , vol.151 , pp. 26-34
    • Niemi, W.D.1    Audi, J.2    Bush, B.3    Carpenter, D.O.4
  • 31
    • 85033542554 scopus 로고    scopus 로고
    • Effects of acute and repeated exposures to Aroclor 1254 in adult rats: motor activity and flavor aversion conditioning
    • Nishida N., Farmer J.D., Kodavanti P.R., Tilson H.A., MacPhail R.C. Effects of acute and repeated exposures to Aroclor 1254 in adult rats: motor activity and flavor aversion conditioning. Fundam Appl Toxicol 1997, 40:68-74.
    • (1997) Fundam Appl Toxicol , vol.40 , pp. 68-74
    • Nishida, N.1    Farmer, J.D.2    Kodavanti, P.R.3    Tilson, H.A.4    MacPhail, R.C.5
  • 32
    • 5044222313 scopus 로고    scopus 로고
    • Hippocampal long-term potentiation (LTP) is reduced by a coplanar PCB congener
    • Ozcan M., Yilmaz B., King W.M., Carpenter D.O. Hippocampal long-term potentiation (LTP) is reduced by a coplanar PCB congener. Neurotoxicology 2004, 25:981-988.
    • (2004) Neurotoxicology , vol.25 , pp. 981-988
    • Ozcan, M.1    Yilmaz, B.2    King, W.M.3    Carpenter, D.O.4
  • 33
    • 77955828105 scopus 로고    scopus 로고
    • Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study
    • Park H.Y., Hertz-Picciotto I., Sovcikova E., Kocan A., Drobna B., Trnovec T. Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study. Environ Health 2010, 9:51.
    • (2010) Environ Health , vol.9 , pp. 51
    • Park, H.Y.1    Hertz-Picciotto, I.2    Sovcikova, E.3    Kocan, A.4    Drobna, B.5    Trnovec, T.6
  • 35
    • 27744499964 scopus 로고    scopus 로고
    • Neuropsychological effects of chronic low-dose exposure to polychlorinated biphenyls (PCBs): a cross-sectional study
    • Peper M., Klett M., Morgenstern R. Neuropsychological effects of chronic low-dose exposure to polychlorinated biphenyls (PCBs): a cross-sectional study. Environ Health 2005, 4:22.
    • (2005) Environ Health , vol.4 , pp. 22
    • Peper, M.1    Klett, M.2    Morgenstern, R.3
  • 36
    • 37749014882 scopus 로고    scopus 로고
    • Developmental exposure to polychlorinated biphenyls PCB153 or PCB126 impairs learning ability in young but not in adult rats
    • Piedrafita B., Erceg S., Cauli O., Monfort P., Felipo V. Developmental exposure to polychlorinated biphenyls PCB153 or PCB126 impairs learning ability in young but not in adult rats. Eur J Neurosci 2008, 27:177-182.
    • (2008) Eur J Neurosci , vol.27 , pp. 177-182
    • Piedrafita, B.1    Erceg, S.2    Cauli, O.3    Monfort, P.4    Felipo, V.5
  • 38
    • 0035354889 scopus 로고    scopus 로고
    • Impairments of memory and learning in older adults exposed to polychlorinated biphenyls via consumption of Great Lakes fish
    • Schantz S.L., Gasior D.M., Polverejan E., McCaffrey R.J., Sweeney A.M., Humphrey H.E., et al. Impairments of memory and learning in older adults exposed to polychlorinated biphenyls via consumption of Great Lakes fish. Environ Health Perspect 2001, 109:605-611.
    • (2001) Environ Health Perspect , vol.109 , pp. 605-611
    • Schantz, S.L.1    Gasior, D.M.2    Polverejan, E.3    McCaffrey, R.J.4    Sweeney, A.M.5    Humphrey, H.E.6
  • 39
    • 0025963562 scopus 로고
    • Sub-chronic exposure of the adult rat to Aroclor 1254 yields regionally-specific changes in central dopaminergic function
    • Seegal R.F., Bush B., Brosch K.O. Sub-chronic exposure of the adult rat to Aroclor 1254 yields regionally-specific changes in central dopaminergic function. Neurotoxicology 1991, 12:55-65.
    • (1991) Neurotoxicology , vol.12 , pp. 55-65
    • Seegal, R.F.1    Bush, B.2    Brosch, K.O.3
  • 40
    • 0030886439 scopus 로고    scopus 로고
    • Endogenous glutamate increases extracellular concentrations of dopamine. GABA, and taurine through NMDA and AMPA/kainate receptors in striatum of the freely moving rat: a microdialysis study
    • Segovia G., Del Arco A., Mora F. Endogenous glutamate increases extracellular concentrations of dopamine. GABA, and taurine through NMDA and AMPA/kainate receptors in striatum of the freely moving rat: a microdialysis study. J Neurochem 1997, 69:1476-1483.
    • (1997) J Neurochem , vol.69 , pp. 1476-1483
    • Segovia, G.1    Del Arco, A.2    Mora, F.3
  • 41
    • 0027491346 scopus 로고
    • Effect of systemic administration of N-methyl-d-aspartic acid on extracellular taurine level measured by microdialysis in the hippocampal CA1 field and striatum of rats
    • Shibanoki S., Kogure M., Sugahara M., Ishikawa K. Effect of systemic administration of N-methyl-d-aspartic acid on extracellular taurine level measured by microdialysis in the hippocampal CA1 field and striatum of rats. J Neurochem 1993, 61:1698-1704.
    • (1993) J Neurochem , vol.61 , pp. 1698-1704
    • Shibanoki, S.1    Kogure, M.2    Sugahara, M.3    Ishikawa, K.4
  • 42
    • 33846155246 scopus 로고    scopus 로고
    • Polychlorinated biphenyls disrupt the actin cytoskeleton in hippocampal neurons
    • Tang F., Yan C., Wu S., Li F., Yu Y., Gao Y., et al. Polychlorinated biphenyls disrupt the actin cytoskeleton in hippocampal neurons. Environ Toxicol Pharmacol 2007, 23:140-146.
    • (2007) Environ Toxicol Pharmacol , vol.23 , pp. 140-146
    • Tang, F.1    Yan, C.2    Wu, S.3    Li, F.4    Yu, Y.5    Gao, Y.6
  • 43
    • 0030983932 scopus 로고    scopus 로고
    • Neurochemical effects of polychlorinated biphenyls: an overview and identification of research needs
    • Tilson H.A., Kodavanti P.R. Neurochemical effects of polychlorinated biphenyls: an overview and identification of research needs. Neurotoxicology 1997, 18:727-743.
    • (1997) Neurotoxicology , vol.18 , pp. 727-743
    • Tilson, H.A.1    Kodavanti, P.R.2
  • 44
    • 77956048917 scopus 로고    scopus 로고
    • Glutamate receptor-mediated taurine release from the hippocampus during oxidative stress
    • Tucker B., Olson J.E. Glutamate receptor-mediated taurine release from the hippocampus during oxidative stress. J Biomed Sci 2010, 17:S10.
    • (2010) J Biomed Sci , vol.17
    • Tucker, B.1    Olson, J.E.2
  • 45
    • 1542345664 scopus 로고    scopus 로고
    • Regulatory role of nitric oxide over extracellular taurine in the hippocampus of freely moving rats
    • Watts J., Segieth J., Pearce B., Whitton P.S. Regulatory role of nitric oxide over extracellular taurine in the hippocampus of freely moving rats. Neurosci Lett 2004, 357:179-182.
    • (2004) Neurosci Lett , vol.357 , pp. 179-182
    • Watts, J.1    Segieth, J.2    Pearce, B.3    Whitton, P.S.4
  • 46
    • 28244455789 scopus 로고    scopus 로고
    • Protective effects of Vitamin E on endocrine disruptors, PCB-induced dopaminergic neurotoxicity
    • Yun J.S., Na H.K., Park K.S., Lee Y.H., Kim E.Y., Lee S.Y., et al. Protective effects of Vitamin E on endocrine disruptors, PCB-induced dopaminergic neurotoxicity. Toxicology 2005, 216:140-146.
    • (2005) Toxicology , vol.216 , pp. 140-146
    • Yun, J.S.1    Na, H.K.2    Park, K.S.3    Lee, Y.H.4    Kim, E.Y.5    Lee, S.Y.6
  • 47
    • 0028275855 scopus 로고
    • Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
    • Zhuo M., Hu Y., Schultz C., Kandel E.R., Hawkins R.D. Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation. Nature 1994, 368:635-639.
    • (1994) Nature , vol.368 , pp. 635-639
    • Zhuo, M.1    Hu, Y.2    Schultz, C.3    Kandel, E.R.4    Hawkins, R.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.