Polychlorinated biphenyls PCB 153 and PCB 126 impair the glutamate-nitric oxide-cgmp pathway in cerebellar neurons in culture by different mechanisms

Neurotoxicity Research

Volumn 16, Issue 2, 2009, Pages 97-105

  Llansola, Marta ^a   Piedrafita, Blanca ^a   Rodrigo, Regina ^a   Montoliu, Carmina ^b   Felipo, Vicente ^a  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b Fundacion Hospital   (Spain)

Author keywords

Cerebellum; CGMP; Learning; NMDA; PCBs

Indexed keywords

CALCIUM; CALMODULIN; CYCLIC GMP; GLUTAMIC ACID; GUANYLATE CYCLASE; N METHYL DEXTRO ASPARTIC ACID; NITRIC OXIDE; POLYCHLORINATED BIPHENYL DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL VIABILITY; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVATION; EXPOSURE; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR MECHANICS; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CYCLIC GMP; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGENTS; GLUTAMIC ACID; N-METHYLASPARTATE; NEURONS; NEUROTOXINS; NITRIC OXIDE; POLYCHLORINATED BIPHENYLS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TIME FACTORS;

RATTUS;

EID: 70449528743     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12640-009-9055-8     Document Type: Article

References (21)

1. MA Aguilar J Minarro V Felipo 2000 Chronic moderate hyperammonemia impairs active and passive avoidance behavior and conditional discrimination learning in rats Exp Neurol 161 704 713 10686089 10.1006/exnr.1999.7299 1:CAS:528:DC%2BD3cXht1Ontbo%3D (Pubitemid 30137027)
2. TC Bellamy J Wood J Garthwaite 2002 On the activation of soluble guanylyl cyclase by nitric oxide Proc Natl Acad Sci USA 99 507 510 11752394 10.1073/pnas.012368499 1:CAS:528:DC%2BD38Xlt1Cqsw%3D%3D (Pubitemid 34060391)
3. O Cauli R Rodrigo B Piedrafita J Boix V Felipo 2007 Inflammation and hepatic encephalopathy: ibuprofen restores learning ability in rats with porto-caval shunts Hepatology 46 514 519 17659565 10.1002/hep.21734 1:CAS:528:DC%2BD2sXhtVSisbzP (Pubitemid 47344787)
4. S Erceg P Monfort M Hernández-Viadel M Llansola C Montoliu V Felipo 2005 Restoration of learning ability in hyperammonemic rats by increasing extracellular cGMP in brain Brain Res 1036 115 121 15725408 10.1016/j.brainres.2004.12.045 1:CAS:528:DC%2BD2MXhslWksbw%3D (Pubitemid 40255850)
5. S Erceg P Monfort M Hernández-Viadel R Rodrigo C Montoliu V Felipo 2005 Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunt Hepatology 45 2 10
6. B Fangstrom A Strid P Grandjean P Weihe A Bergman 2005 A retrospective study of PBDEs and PCBs in human milk from the Faroe Islands Environ Health 4 12 16014177 10.1186/1476-069X-4-12 (Pubitemid 41378985)
7. O Faroon D Jones C de Rosa 2001 Effects of polychlorinated biphenyls on the nervous system Toxicol Ind Health 16 305 333 11693948 10.1177/ 074823370001600708 1:STN:280:DC%2BD3Mnjs12isw%3D%3D
8. V Felipo E Grau MD Miñana S Grisolía 1993 Ammonium injection induces an N methyl D aspartate receptor mediated proteolysis of the microtubule associated protein MAP 2 J Neurochem 60 1626 1630 8473887 10.1111/j.1471-4159.1993.tb13384.x 1:CAS:528:DyaK3sXktVaksLs%3D
9. V Felipo MD Miñana H Cabedo S Grisolía 1994 L-carnitine increases the affinity of glutamate for quisqualate receptors and prevents glutamate neurotoxicity Neurochem Res 19 373 377 7909920 10.1007/BF00971588 1:CAS:528:DyaK2cXhsFCmt7Y%3D
10. KA Gray MA Klebanoff JW Brock H Zhou R Darden L Needham MP Longnecker 2005 In utero exposure to background levels of polychlorinated biphenyls and cognitive functioning among school-age children Am J Epidemiol 162 17 26 15961582 10.1093/aje/kwi158 (Pubitemid 40884996)
11. C Hermenegildo C Montoliu M Llansola MD Munoz JM Gaztelu MD Minana V Felipo 1998 Chronic hyperammonemia impairs the glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo Eur J NeuroSci 10 3201 3209 9786213 10.1046/j.1460-9568.1998.00329.x 1:STN:280: DyaK1M%2FgtVWmsA%3D%3D (Pubitemid 29070616)
12. K Inoue K Harada K Takenaka S Uehara M Kono T Shimizu T Takasuga K Senthilkumar F Yamashita A Koizumi 2006 Levels and concentration ratios of polychlorinated biphenyls and polybrominated diphenyl ethers in serum and breast milk in Japanese mothers Environ Health Perspect 114 1179 1185 16882522 1:CAS:528:DC%2BD28XptVeju7s%3D
13. JL Jacobson SW Jacobson 1996 Intellectual impairment in children exposed to polychlorinated biphenyls in utero N Engl J Med 335 783 789 8703183 10.1056/NEJM199609123351104 1:CAS:528:DyaK28XlvVGqsbc%3D (Pubitemid 26296538)
14. PJ Landrigan 2001 Pesticides and polychlorinated biphenyls (PCBs): an analysis of the evidence that they impair children's neurobehavioral development Mol Genet Metab 73 11 17 11350178 10.1006/mgme.2001.3177 1:CAS:528: DC%2BD3MXjtlOqtL8%3D (Pubitemid 34177619)
15. MD Minana C Montoliu M Llansola S Grisolia V Felipo 1998 Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons Neuropharmacology 37 847 857 9776381 10.1016/S0028-3908(98)00074-4 1:CAS:528:DyaK1cXmt1Sntrk%3D (Pubitemid 28375752)
16. P Monfort R Corbalán L Martinez JC López-Talavera J Córdoba V Felipo 2001 Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis Neuroscience 104 1119 1125 11457595 10.1016/S0306-4522(01)00128-2 1:CAS:528:DC%2BD3MXlt1SitL4%3D (Pubitemid 32701971)
17. C Montoliu M Llansola E Kosenko R Corbalán V Felipo 1999 Role of cyclic GMP in glutamate neurotoxicity in primary cultures of cerebellar neurons Neuropharmacology 38 1883 1891 10608283 10.1016/S0028-3908(99)00071-4 1:CAS:528:DyaK1MXotVOqs7Y%3D (Pubitemid 29509726)
18. B Piedrafita O Cauli C Montoliu V Felipo 2007 The function of the glutamate-nitric oxide-cGMP pathway in brain in vivo and learning ability decrease in parallel in mature compared to young rats Learn Mem 14 254 258 17412964 10.1101/lm.541307 1:CAS:528:DC%2BD1cXms1Oruro%3D (Pubitemid 46625627)
19. B Piedrafita S Erceg O Cauli P Monfort V Felipo 2008 Developmental exposure to polychlorinated biphenyls PCB153 or PCB126 impairs learning ability in young but not in adult rats Eur J Neurosci 27 177 182 18093177
20. SL Schantz BW Seo J Moshtaghian RE Peterson RW Moore 1996 Effects of gestational and lactational exposure to TCDD or coplanar PCBs on spatial learning Neurotoxicol Teratol 18 305 313 8725643 10.1016/S0892-0362(96)90033-1 1:CAS:528:DyaK28Xjtl2ku7Y%3D (Pubitemid 26199582)
21. 2+ signalling in cochlear inner hair cells Eur J NeuroSci 21 2912 2922 15978003 10.1111/j.1460-9568.2005.04135.x (Pubitemid 40917056)