Measurement of 3-hydroxyisovaleric acid in urine from marginally biotin-deficient humans by UPLC-MS/MS

Analytical and Bioanalytical Chemistry

Volumn 401, Issue 9, 2011, Pages 2805-2810

  Horvath, Thomas D ^a   Matthews, Nell I ^a   Stratton, Shawna L ^a   Mock, Donald M ^a   Boysen, Gunnar ^b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

3 hydroxyisovaleric acid; Biotin status indicator; Marginal biotin deficiency; Ultra high performance liquid chromatography; UPLC MS MS

Indexed keywords

BIOMONITORING; CLINICAL SITUATIONS; CORRELATION COEFFICIENT; DATA SETS; EGG WHITE; EXCRETION RATES; HUMAN URINE; LINEAR RELATIONSHIPS; MARGINAL BIOTIN DEFICIENCY; MEAN CONCENTRATIONS; SAMPLE PREPARATION; STANDARD DEVIATION; UPLC-MS/MS;

BODY FLUIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MONITORING;

COENZYMES;

3 HYDROXYISOVALERIC ACID; BETA-HYDROXYISOVALERIC ACID; BIOLOGICAL MARKER; BIOTIN; CREATININE; EGG WHITE; VALERIC ACID DERIVATIVE;

ADULT; BIOTINIDASE DEFICIENCY; CALIBRATION; CHEMICALLY INDUCED DISORDER; CONFERENCE PAPER; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; METHODOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STANDARD; TANDEM MASS SPECTROMETRY; URINE;

ADULT; BIOLOGICAL MARKERS; BIOTIN; BIOTINIDASE DEFICIENCY; CALIBRATION; CHROMATOGRAPHY, LIQUID; CREATININE; EGG WHITE; FEMALE; HUMANS; MALE; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; VALERATES;

EID: 81855201862     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-5356-x     Document Type: Conference Paper

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