Determination of 3-hydroxyisovalerylcarnitine and other acylcarnitine levels using liquid chromatography-tandem mass spectrometry in serum and urine of a patient with multiple carboxylase deficiency

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 870, Issue 2, 2008, Pages 154-159

  Maeda, Yasuhiro ^a   Ito, Tetsuya ^b   Ohmi, Hironori ^a   Yokoi, Kyoko ^b   Nakajima, Yoko ^b   Ueta, Akihito ^b   Kurono, Yukihisa ^a   Togari, Hajime ^b   Sugiyama, Naruji ^c  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^c AICHI GAKUIN UNIVERSITY   (Japan)

Author keywords

3 Hydroxyisovalerylcarnitine; 3 Methylcrotonylcarnitine; Acylcarnitine; Holocarboxylase synthetase deficiency; LC MS MS; Multiple carboxylase deficiency; Newborn screening; Tandem mass spectrometry; Tiglylcarnitine

Indexed keywords

ACYLCARNITINE; CONCENTRATION (COMPOSITION); ELSEVIER (CO); HIGH ACCURACY; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY (LC MS MS); MULTIPLE-REACTION MONITORING (MRM); ORGANIC ACIDEMIAS; REPRODUCIBILITY; SYNTHESIS (OF CHIRAL IONIC LIQUIDS); TANDEM MASS SPECTROMETRIC;

CHROMATOGRAPHIC ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIC LIQUIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; SPECTROMETRY; STANDARDS;

BODY FLUIDS;

2 METHYLBUTYRYLCARNITINE; 3 HYDROXYISOVALERYLCARNITINE; 3 METHYLCROTONYLCARNITINE; ACETYLCARNITINE; ACYLCARNITINE; BUTYRYLCARNITINE; CARNITINE; GLUTARYLCARNITINE; HEXANOYLCARNITINE; ISOBUTYRYLCARNITINE; ISOVALERYLCARNITINE; MALONYLCARNITINE; OCTANOYLCARNITINE; PROPIONYLCARNITINE; SUCCINYLCARNITINE; TIGLYLCARNITINE;

ACIDEMIA; ANALYTIC METHOD; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DISORDERS OF CARBOHYDRATE METABOLISM; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; PRESCHOOL CHILD; PRIORITY JOURNAL; REPRODUCIBILITY; SYNTHESIS; TANDEM MASS SPECTROMETRY; URINE LEVEL;

CARNITINE; CHROMATOGRAPHY, LIQUID; HUMANS; MULTIPLE CARBOXYLASE DEFICIENCY; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 47249124537     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.11.037     Document Type: Article

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