Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants

Neurology

Volumn 49, Issue 5, 1997, Pages 1444-1447

  Mock, Donald M ^a   Dyken, Mark E ^b  

^a ARKANSAS CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; BIOTIN; CARBAMAZEPINE; FELBAMATE; PHENOBARBITAL; PHENYTOIN; VALPROIC ACID;

ADULT; ANTICONVULSANT THERAPY; ARTICLE; BIOTRANSFORMATION; CATABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; KIDNEY FUNCTION; MALE; PRIORITY JOURNAL; SEIZURE; URINARY EXCRETION; VITAMIN BLOOD LEVEL; VITAMIN DEFICIENCY; VITAMIN METABOLISM;

EID: 0030695279     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.49.5.1444     Document Type: Article

References (10)

1. Krause K-H, Berlit P, Bonjour J-P. Impaired biotin status in anticonvulsant therapy. Ann Neurol 1982;12:485-486.
2. Krause K-H, Berlit P, Bonjour J-P. Vitamin status in patients on chronic anticonvulsant therapy. Int J Vitam Nutr Res 1982;52:375-385.
3. Krause K-H, Kochen W, Berli PT, Bonjour J-P. Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy. Int J Vitam Nutr Res 1984;54:217-222.
4. Mock DM. Determinations of biotin in biological fluids. In: McCormick DB, Suttie JW, Wagner C, eds. Vitamins and co-enzymes, part I, series methods of enzymology. San Diego, CA: Academic Press, 1997:265-275.
5. Mock N, Malik M, Stumbo P, Bishop W, Mock D. Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased status in experimental biotin deficiency. Am J Clin Nutr 1997;65:951-958.
6. Mock NI, Mock DM. Biotin deficiency in rats: disturbances of leucine metabolism are detectable early. J Nutr 1992;122: 1493-1499.
7. Wolf B. Disorders of biotin metabolism. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The metabolic and molecular basis of inherited disease, vol II. 7th ed. New York: McGraw-Hill, 1995:3151-3177.
8. Sweetman L, Williams J. Branched chain organic acidurias. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The metabolic and molecular basis of inherited disease, vol 1. 7th ed. New York: McGraw-Hill, 1995:1387-1422.
9. Mock DM, Biotin. In: Ziegler EE, Filer LJ Jr, eds. Present knowledge in nutrition. Washington, DC: International Life Sciences Institutes-Nutrition Foundation, 1996:220-235.
10. Said HM, Reyadh R, Nylander W. Biotin transport and anticonvulsant drugs. Am J Clin Nutr 1989;49:127-131.