Gender-specific increase of bone mass by CART peptide treatment is ovary-dependent

Journal of Bone and Mineral Research

Volumn 26, Issue 12, 2011, Pages 2886-2898

  Gerrits, Han ^a   Bakker, Nicole E C ^a   Van De Ven De Laat, Cindy J M ^a   Bourgondien, Freek G M ^a   Peddemors, Carolien ^a   Litjens, Ralph G M ^a   Kok, Han J ^a   Vogel, Gerard M T ^a   Krajnc Franken, Magda A M ^a   Gossen, Jan A ^a,b  

^a NV ORGANON   (Netherlands)

^b Amgen   (Netherlands)

Author keywords

CART peptide treatment; CART transgenic mice; OVX, bone mass; treatment of bone disease

Indexed keywords

COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE 39-89; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE 48-89; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE 55-102; ESTRADIOL; PLACEBO; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MASS; CONTROLLED STUDY; CORTICAL BONE; DRUG ACCUMULATION; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG EFFECT; DRUG HALF LIFE; FEMALE; MALE; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST ACTIVITY; OVARIECTOMY; OVARY; POSTMENOPAUSE; PREMENOPAUSE; SEX DIFFERENCE; SUSTAINED DRUG RELEASE; TRABECULAR BONE; TREATMENT RESPONSE; WILD TYPE;

ANIMALS; BONE AND BONES; ESTRADIOL; FEMALE; GONADOTROPINS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; ORGAN SIZE; OVARIECTOMY; OVARY; RATS; RECOMBINANT PROTEINS; SEX CHARACTERISTICS; X-RAY MICROTOMOGRAPHY;

EID: 81855184647     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.500     Document Type: Article

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