-
1
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
-
Ducy P, Amling M, Takeda S, Priemel M, Schilling A, Beil F, Shen J, Vinson C, Rueger J, Karsenty G. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 2000;100:197-207.
-
(2000)
Cell
, vol.100
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
Priemel, M.4
Schilling, A.5
Beil, F.6
Shen, J.7
Vinson, C.8
Rueger, J.9
Karsenty, G.10
-
2
-
-
0036847619
-
Leptin regulates bone formation via the sympathetic nervous system
-
Takeda S, Elefteriou F, Levasseur R, Liu X, Zhao L, Parker KL, Armstrong D, Ducy P, Karsenty G. Leptin regulates bone formation via the sympathetic nervous system. Cell 2002;111:305-17.
-
(2002)
Cell
, vol.111
, pp. 305-317
-
-
Takeda, S.1
Elefteriou, F.2
Levasseur, R.3
Liu, X.4
Zhao, L.5
Parker, K.L.6
Armstrong, D.7
Ducy, P.8
Karsenty, G.9
-
3
-
-
0033773314
-
A neuro (endo)crine regulation of bone remodeling
-
Amling M, Takeda S, Karsenty G. A neuro (endo)crine regulation of bone remodeling. Bioessays 2000;22:970-5.
-
(2000)
Bioessays
, vol.22
, pp. 970-975
-
-
Amling, M.1
Takeda, S.2
Karsenty, G.3
-
4
-
-
0035787134
-
Leptin controls bone formation through a hypothalamic relay
-
Karsenty G. Leptin controls bone formation through a hypothalamic relay. Recent Prog Horm Res 2001;56:401-15.
-
(2001)
Recent Prog Horm Res
, vol.56
, pp. 401-415
-
-
Karsenty, G.1
-
5
-
-
0034714050
-
Leptin is a potent stimulator of bone growth in ob/ob mice
-
Steppan C Crawford T, Chidsey-Frink K, Ke H, Swick A. Leptin is a potent stimulator of bone growth in ob/ob mice. Regul Pept 2000;92:73-8.
-
(2000)
Regul Pept
, vol.92
, pp. 73-78
-
-
Steppan, C.1
Crawford, T.2
Chidsey-Frink, K.3
Ke, H.4
Swick, A.5
-
6
-
-
1542316258
-
Leptin deficiency produces contrasting phenotypes in bones of the limb and spine
-
Hamrick MW, Pennington C, Newton D, Xie D, Isales C. Leptin deficiency produces contrasting phenotypes in bones of the limb and spine. Bone 2004;34:376-83.
-
(2004)
Bone
, vol.34
, pp. 376-383
-
-
Hamrick, M.W.1
Pennington, C.2
Newton, D.3
Xie, D.4
Isales, C.5
-
7
-
-
18744376564
-
Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo
-
Cornish J, Callon K, Bava U, Lin C, Naot D, Hill B. Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo. J Endocrinol 2002;175:405-15.
-
(2002)
J Endocrinol
, vol.175
, pp. 405-415
-
-
Cornish, J.1
Callon, K.2
Bava, U.3
Lin, C.4
Naot, D.5
Hill, B.6
-
8
-
-
0037174178
-
Role of leptin in bone growth: Central player or peripheral supporter?
-
Reseland J, Gordeladze J. Role of leptin in bone growth: central player or peripheral supporter? FEBS Lett 2002;528:40-2.
-
(2002)
FEBS Lett
, vol.528
, pp. 40-42
-
-
Reseland, J.1
Gordeladze, J.2
-
9
-
-
34247546688
-
Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice
-
Iwaniec UT, Boghossian S, Lapke P, Turner R, Kalra S. Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice. Peptides 2007; 28:1012-9.
-
(2007)
Peptides
, vol.28
, pp. 1012-1019
-
-
Iwaniec, U.T.1
Boghossian, S.2
Lapke, P.3
Turner, R.4
Kalra, S.5
-
10
-
-
0031623306
-
The MONA LISA hypothesis in the time of leptin
-
Bray GA, York DA. The MONA LISA hypothesis in the time of leptin. Recent Prog Horm Res 1998;53:95-117.
-
(1998)
Recent Prog Horm Res
, vol.53
, pp. 95-117
-
-
Bray, G.A.1
York, D.A.2
-
11
-
-
33751507119
-
β1β2-adrenergic receptor ko mice have decreased total body and cortical bone mass despite increased trabecular bone number
-
Pierroz D, Muzzin P, Glatt V. β1β2-adrenergic receptor ko mice have decreased total body and cortical bone mass despite increased trabecular bone number. J Bone Miner Res 2004;19(Suppl.1):1121.
-
(2004)
J Bone Miner Res
, vol.19
, Issue.SUPPL.1
, pp. 1121
-
-
Pierroz, D.1
Muzzin, P.2
Glatt, V.3
-
12
-
-
15844384047
-
Leptin regulation of bone resorption by the sympathetic nervous system and CART
-
Elefteriou F, Ahn J, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards W, Bannon T, Noda M, Clement K, Vaisse C, Karsenty G. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature 2005;434:514-20.
-
(2005)
Nature
, vol.434
, pp. 514-520
-
-
Elefteriou, F.1
Ahn, J.2
Takeda, S.3
Starbuck, M.4
Yang, X.5
Liu, X.6
Kondo, H.7
Richards, W.8
Bannon, T.9
Noda, M.10
Clement, K.11
Vaisse, C.12
Karsenty, G.13
-
13
-
-
0025914202
-
Effects of neonatal sympathectomy and capsaicin treatment on bone remodeling in rats
-
Hill E, Turner R, Elde R. Effects of neonatal sympathectomy and capsaicin treatment on bone remodeling in rats. Neuroscience 1991;44:747-55.
-
(1991)
Neuroscience
, vol.44
, pp. 747-755
-
-
Hill, E.1
Turner, R.2
Elde, R.3
-
14
-
-
51749091747
-
Central control of cortical bone homeostasis: Neuropeptide Y exerts a negative effect on cortical bone formation. Frontiers of Skeletal Biology
-
Davos, Switzerland
-
Baldock PA, Allison S, Sainsbury A, Enriquez R, Gardiner EM, Herzog H. Central control of cortical bone homeostasis: Neuropeptide Y exerts a negative effect on cortical bone formation. Frontiers of Skeletal Biology. 11th Workshop on Cell Biology of Bone and Cartilage in Health and Disease. (Davos, Switzerland);2006.
-
(2006)
11th Workshop on Cell Biology of Bone and Cartilage in Health and Disease
-
-
Baldock, P.A.1
Allison, S.2
Sainsbury, A.3
Enriquez, R.4
Gardiner, E.M.5
Herzog, H.6
-
15
-
-
0036212496
-
Hypothalamic Y2 receptors regulate bone formation
-
Baldock PA, Sainsbury A, Couzens M, Enriquez RF, Thomas GP, Gardiner E, Herzog H. Hypothalamic Y2 receptors regulate bone formation. J Clin Invest 2002;109:915-21.
-
(2002)
J Clin Invest
, vol.109
, pp. 915-921
-
-
Baldock, P.A.1
Sainsbury, A.2
Couzens, M.3
Enriquez, R.F.4
Thomas, G.P.5
Gardiner, E.6
Herzog, H.7
-
16
-
-
34547107887
-
Greater bone formation of Y2 knockout mice is associated with increased osteoprogenitor numbers and altered Y1 receptor expression
-
Lunberg P, Allison SJ, Lee NJ, Baldock PA, Brouard N, Rost S, Enriquez RF, Sainsbury A, Lamghari M, Simmons P, Eisman JA, Gardiner EM, Herzog H. Greater bone formation of Y2 knockout mice is associated with increased osteoprogenitor numbers and altered Y1 receptor expression. J Biol Chem 2007;282:19082-91.
-
(2007)
J Biol Chem
, vol.282
, pp. 19082-19091
-
-
Lunberg, P.1
Allison, S.J.2
Lee, N.J.3
Baldock, P.A.4
Brouard, N.5
Rost, S.6
Enriquez, R.F.7
Sainsbury, A.8
Lamghari, M.9
Simmons, P.10
Eisman, J.A.11
Gardiner, E.M.12
Herzog, H.13
-
17
-
-
34547105098
-
Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis
-
Baldock PA, Allison SJ, Lunberg P, Lee NJ, Slack K, Lin ED, Enriquez RF, McDonald MM, Zhang L, During MJ, Little DG, Eisman JA, Gardiner EM, Yulyaningsih E, Lin S, Sainsbury A, Herzog H. Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis. J Biol Chem 2007;282:19092-102.
-
(2007)
J Biol Chem
, vol.282
, pp. 19092-19102
-
-
Baldock, P.A.1
Allison, S.J.2
Lunberg, P.3
Lee, N.J.4
Slack, K.5
Lin, E.D.6
Enriquez, R.F.7
McDonald, M.M.8
Zhang, L.9
During, M.J.10
Little, D.G.11
Eisman, J.A.12
Gardiner, E.M.13
Yulyaningsih, E.14
Lin, S.15
Sainsbury, A.16
Herzog, H.17
-
18
-
-
33749248697
-
Hypothalamic regulation of cortical bone mass: Opposing activity of Y2 receptor and leptin pathways
-
Baldock PA, Allison SJ, McDonald MM, Sainsbury A, Enriquez R, Little DG, Eisman JA, Gardiner EM, Herzog H. Hypothalamic regulation of cortical bone mass: opposing activity of Y2 receptor and leptin pathways. J Bone Miner Res 2006;21:1600-7.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 1600-1607
-
-
Baldock, P.A.1
Allison, S.J.2
McDonald, M.M.3
Sainsbury, A.4
Enriquez, R.5
Little, D.G.6
Eisman, J.A.7
Gardiner, E.M.8
Herzog, H.9
-
19
-
-
0030715274
-
Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland
-
Koylu EO, Couceyro PR, Lambert PD, Ling NC, DeSouza EB, Kuhar MJ. Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland. J Neuroendocrinol 1997;9:823-33.
-
(1997)
J Neuroendocrinol
, vol.9
, pp. 823-833
-
-
Koylu, E.O.1
Couceyro, P.R.2
Lambert, P.D.3
Ling, N.C.4
DeSouza, E.B.5
Kuhar, M.J.6
-
20
-
-
21344440565
-
The effects of cocaine on CART expression in the rat nucleus accumbens: A possible role for corticosterone
-
Hunter RG, Vicentic A, Rogge G, Kuhar MJ. The effects of cocaine on CART expression in the rat nucleus accumbens: a possible role for corticosterone. Eur J Pharmacol 2005;517:45-50.
-
(2005)
Eur J Pharmacol
, vol.517
, pp. 45-50
-
-
Hunter, R.G.1
Vicentic, A.2
Rogge, G.3
Kuhar, M.J.4
-
22
-
-
0032492893
-
Hypothalamic CART is a new anorectic peptide regulated by leptin
-
Kristensen P, Judge ME, Thim L, Ribel U, Christjansen KN, Wulff BS, Clausen JT, Jensen PB, Madsen OD, Vrang N, Larsen PJ, Hastrup S. Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 1998;393:72-6.
-
(1998)
Nature
, vol.393
, pp. 72-76
-
-
Kristensen, P.1
Judge, M.E.2
Thim, L.3
Ribel, U.4
Christjansen, K.N.5
Wulff, B.S.6
Clausen, J.T.7
Jensen, P.B.8
Madsen, O.D.9
Vrang, N.10
Larsen, P.J.11
Hastrup, S.12
-
23
-
-
0037008424
-
Origins of skeletal pain: Sensory and sympathetic innervation of the mouse femur
-
Mach D, Rogers S, Sabino M, Luger N, Schwei M, Pomonis M, Keyser C, Clohisy D, Adams D, O'Leary P, Mantyh P. Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience 2000;113:155-66.
-
(2000)
Neuroscience
, vol.113
, pp. 155-166
-
-
Mach, D.1
Rogers, S.2
Sabino, M.3
Luger, N.4
Schwei, M.5
Pomonis, M.6
Keyser, C.7
Clohisy, D.8
Adams, D.9
O'Leary, P.10
Mantyh, P.11
-
24
-
-
0142241146
-
Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging
-
Duan Y, Beck T, Wang X, Seeman E. Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging. J Bone Miner Res 2003;18:1766-74.
-
(2003)
J Bone Miner Res
, vol.18
, pp. 1766-1774
-
-
Duan, Y.1
Beck, T.2
Wang, X.3
Seeman, E.4
-
25
-
-
0034802121
-
Absence of cocaine-and amphetamine-regulated transcript results in obesity in mice fed a high caloric diet
-
Asnicar MA, Smith DP, Yang DD, Heiman ML, Fox N, Chen YF, Hsiung HM, Köster A. Absence of cocaine-and amphetamine-regulated transcript results in obesity in mice fed a high caloric diet. Endocrinology 2001;142:4394-400.
-
(2001)
Endocrinology
, vol.142
, pp. 4394-4400
-
-
Asnicar, M.A.1
Smith, D.P.2
Yang, D.D.3
Heiman, M.L.4
Fox, N.5
Chen, Y.F.6
Hsiung, H.M.7
Köster, A.8
-
26
-
-
0028801169
-
Perspectives of pQCT technology associated to biomechanical studies in skeletal research employing rat models
-
Ferretti JL. Perspectives of pQCT technology associated to biomechanical studies in skeletal research employing rat models. Bone 1995;17(Suppl.):353S-64S.
-
(1995)
Bone
, vol.17
, Issue.SUPPL.
-
-
Ferretti, J.L.1
-
27
-
-
0028874563
-
Assessing bone quantity by pQCT
-
Gasser JA. Assessing bone quantity by pQCT. Bone 1995;17(Suppl.):145S-54S.
-
(1995)
Bone
, vol.17
, Issue.SUPPL.
-
-
Gasser, J.A.1
-
28
-
-
0029880186
-
Genetic variability in adult bone density among inbred strains of mice
-
Beamer WG, Donahue LR, Rosen CJ, Baylink DJ. Genetic variability in adult bone density among inbred strains of mice. Bone 1996;18:397-403.
-
(1996)
Bone
, vol.18
, pp. 397-403
-
-
Beamer, W.G.1
Donahue, L.R.2
Rosen, C.J.3
Baylink, D.J.4
-
29
-
-
25144444293
-
Muscle-bone interactions in dystrophin-deficient and myostatin-deficient mice
-
Montgomery E, Pennington C, Isales CM, Hamrick MW. Muscle-bone interactions in dystrophin-deficient and myostatin-deficient mice. Anat Rec 2005;286A:814-22.
-
(2005)
Anat Rec
, vol.286 A
, pp. 814-822
-
-
Montgomery, E.1
Pennington, C.2
Isales, C.M.3
Hamrick, M.W.4
-
30
-
-
33644530668
-
Increased muscle mass with myostatin deficiency improves gains in bone strength with exercise
-
Hamrick MW, Samaddar T, Pennington C, McCormick J. Increased muscle mass with myostatin deficiency improves gains in bone strength with exercise. J Bone Miner Res 2006;21:477-83.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 477-483
-
-
Hamrick, M.W.1
Samaddar, T.2
Pennington, C.3
McCormick, J.4
-
31
-
-
44449087465
-
Leptin and the sympathetic connection of fat to bone
-
Hamrick MW, Ferrari SL. Leptin and the sympathetic connection of fat to bone. Osteoporos Int 2008;19:905-12.
-
(2008)
Osteoporos Int
, vol.19
, pp. 905-912
-
-
Hamrick, M.W.1
Ferrari, S.L.2
-
32
-
-
24644451507
-
Targeted deletion of melanocortin receptor subtypes 3 and 4, but not CART, alters nutrient partitioning and compromises behavioral and metabolic responses to leptin
-
Zhang Y, Kilroy G, Henagan T, Pric-Uhing V, Richards WG, Bannon AW, Mynatt RL, Gettys TW. Targeted deletion of melanocortin receptor subtypes 3 and 4, but not CART, alters nutrient partitioning and compromises behavioral and metabolic responses to leptin. FASEB J 2005;19:1482-91.
-
(2005)
FASEB J
, vol.19
, pp. 1482-1491
-
-
Zhang, Y.1
Kilroy, G.2
Henagan, T.3
Pric-Uhing, V.4
Richards, W.G.5
Bannon, A.W.6
Mynatt, R.L.7
Gettys, T.W.8
-
33
-
-
19044381754
-
Leptin treatment induces loss of bone marrow adipocytes and increases bone formation in leptin-deficient ob/ob mice
-
Hamrick MW, Della-Fera MA, Choi Y, Pennington C, Hartzell D, Baile CA. Leptin treatment induces loss of bone marrow adipocytes and increases bone formation in leptin-deficient ob/ob mice. J Bone Miner Res 2005;20:994-1001.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 994-1001
-
-
Hamrick, M.W.1
Della-Fera, M.A.2
Choi, Y.3
Pennington, C.4
Hartzell, D.5
Baile, C.A.6
-
34
-
-
33751518058
-
Intrahypothalamic injections of leptin increase adipocyte apoptosis in peripheral fat pad and in bone marrow
-
Hamrick MW, Della-Fera MA, Hartzell D, Choi Y-H, Baile CA. Intrahypothalamic injections of leptin increase adipocyte apoptosis in peripheral fat pad and in bone marrow. Cell Tissue Res 2007;327:133-41.
-
(2007)
Cell Tissue Res
, vol.327
, pp. 133-141
-
-
Hamrick, M.W.1
Della-Fera, M.A.2
Hartzell, D.3
Choi, Y.-H.4
Baile, C.A.5
-
35
-
-
23844551316
-
Novel treatments for obesity and osteoporosis: Targeting apoptotic pathways in adipocytes
-
Nelson-Dooley C, Della-Fera MA, Hamrick MW, Baile CA. Novel treatments for obesity and osteoporosis: targeting apoptotic pathways in adipocytes. Curr Med Chem 2005;12:2215-25.
-
(2005)
Curr Med Chem
, vol.12
, pp. 2215-2225
-
-
Nelson-Dooley, C.1
Della-Fera, M.A.2
Hamrick, M.W.3
Baile, C.A.4
-
36
-
-
0032982438
-
Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes
-
Thomas T, Gori F, Khosla S, Jensen M, Burguera B, Riggs B. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 1999;140:1630-8.
-
(1999)
Endocrinology
, vol.140
, pp. 1630-1638
-
-
Thomas, T.1
Gori, F.2
Khosla, S.3
Jensen, M.4
Burguera, B.5
Riggs, B.6
-
37
-
-
0034842784
-
Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis
-
Justesen J, Stenderup K, Ebbesen E, Mosekilde L, Steiniche T, Kassem M. Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology 2001;2:165-71.
-
(2001)
Biogerontology
, vol.2
, pp. 165-171
-
-
Justesen, J.1
Stenderup, K.2
Ebbesen, E.3
Mosekilde, L.4
Steiniche, T.5
Kassem, M.6
-
38
-
-
0036724870
-
Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis
-
Verma S, Rajaratnam J, Denton J, Hoyland JA, Byers RJ. Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis. J Clin Pathol 2002;55:693-8.
-
(2002)
J Clin Pathol
, vol.55
, pp. 693-698
-
-
Verma, S.1
Rajaratnam, J.2
Denton, J.3
Hoyland, J.A.4
Byers, R.J.5
|