메뉴 건너뛰기




Volumn 32, Issue 12, 2011, Pages 1789-1797

TLR signaling-mediated differential histone modification at IL-10 and IL-12 promoter region leads to functional impairments in tumor-associated macrophages

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 10; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 12; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

EID: 81855173525     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr208     Document Type: Article
Times cited : (31)

References (42)
  • 1
    • 78651073833 scopus 로고    scopus 로고
    • The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and nonsmall cell lung cancer
    • Bremnes,R.M. et al. (2011) The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and nonsmall cell lung cancer. J. Thorac. Oncol., 6, 209-217.
    • (2011) J. Thorac. Oncol. , vol.6 , pp. 209-217
    • Bremnes, R.M.1
  • 2
    • 56749107194 scopus 로고    scopus 로고
    • The tumor microenvironment and its contribution to tumor evolution toward metastasis
    • Lorusso,G. et al. (2008) The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem. Cell Biol., 130, 1091-1103.
    • (2008) Histochem. Cell Biol. , vol.130 , pp. 1091-1103
    • Lorusso, G.1
  • 3
    • 79953028602 scopus 로고    scopus 로고
    • The role of tumor-infiltrating immune cells and Chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer
    • Bremnes,R.M. et al. (2011) The role of tumor-infiltrating immune cells and Chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer. J. Thorac. Oncol., 6, 824-833.
    • (2011) J. Thorac. Oncol. , vol.6 , pp. 824-833
    • Bremnes, R.M.1
  • 4
    • 0037899253 scopus 로고    scopus 로고
    • Role of tissue stroma in cancer cell invasion
    • De Wever,O. et al. (2003) Role of tissue stroma in cancer cell invasion. J. Pathol., 200, 429-447.
    • (2003) J. Pathol. , vol.200 , pp. 429-447
    • De Wever, O.1
  • 5
    • 53549102755 scopus 로고    scopus 로고
    • The tumor microenvironment and its role in promoting tumor growth
    • Whiteside,T.L. (2008) The tumor microenvironment and its role in promoting tumor growth. Oncogene, 27, 5904-5912.
    • (2008) Oncogene , vol.27 , pp. 5904-5912
    • Whiteside, T.L.1
  • 6
    • 0026689558 scopus 로고
    • The origin and function of tumor-associated macrophages
    • Mantovani,A. et al. (1992) The origin and function of tumor-associated macrophages. Immunol. Today, 13, 265-270.
    • (1992) Immunol. Today , vol.13 , pp. 265-270
    • Mantovani, A.1
  • 7
    • 0033903714 scopus 로고    scopus 로고
    • Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer
    • Ueno,T. et al. (2000) Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer. Clin. Cancer Res., 6, 3282-3289.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3282-3289
    • Ueno, T.1
  • 8
    • 0031709864 scopus 로고    scopus 로고
    • Tumor-induced immune dysfunction: the macrophage connection
    • Elgert,K.D. et al. (1998) Tumor-induced immune dysfunction: the macrophage connection. J. Leukoc. Biol., 64, 275-290.
    • (1998) J. Leukoc. Biol. , vol.64 , pp. 275-290
    • Elgert, K.D.1
  • 9
    • 3142644996 scopus 로고    scopus 로고
    • Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression
    • Mantovani,A. et al. (2004) Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. Eur. J. Cancer, 40, 1660-1667.
    • (2004) Eur. J. Cancer , vol.40 , pp. 1660-1667
    • Mantovani, A.1
  • 10
    • 33845573580 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced gene expression in murine macrophages is enhanced by prior exposure to oxLDL
    • Groeneweg,M. et al. (2006) Lipopolysaccharide-induced gene expression in murine macrophages is enhanced by prior exposure to oxLDL. J. Lipid Res., 47, 2259-2267.
    • (2006) J. Lipid Res. , vol.47 , pp. 2259-2267
    • Groeneweg, M.1
  • 11
    • 0021207692 scopus 로고
    • Potent activation of mouse macrophages by recombinant interferon-gamma
    • Varesio,L. et al. (1984) Potent activation of mouse macrophages by recombinant interferon-gamma. Cancer Res., 44, 4465-4469.
    • (1984) Cancer Res. , vol.44 , pp. 4465-4469
    • Varesio, L.1
  • 12
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy
    • Sica,A. et al. (2006) Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur. J. Cancer, 42, 717-727.
    • (2006) Eur. J. Cancer , vol.42 , pp. 717-727
    • Sica, A.1
  • 13
    • 0034650833 scopus 로고    scopus 로고
    • Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages
    • Sica,A. et al. (2000) Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages. J. Immunol., 164, 762-767.
    • (2000) J. Immunol. , vol.164 , pp. 762-767
    • Sica, A.1
  • 14
    • 0032867830 scopus 로고    scopus 로고
    • Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis
    • Takanami,I. et al. (1999) Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis. Oncology, 57, 138-142.
    • (1999) Oncology , vol.57 , pp. 138-142
    • Takanami, I.1
  • 15
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek,R.D. et al. (1996) Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res., 56, 4625-4629.
    • (1996) Cancer Res. , vol.56 , pp. 4625-4629
    • Leek, R.D.1
  • 16
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard,J.W. (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer, 4, 71-78.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 17
    • 77956362433 scopus 로고    scopus 로고
    • Intratumoral macrophage counts correlate with tumor progression in colorectal cancer
    • Kang,J.C. et al. (2010) Intratumoral macrophage counts correlate with tumor progression in colorectal cancer. J. Surg. Oncol., 102, 242-248.
    • (2010) J. Surg. Oncol. , vol.102 , pp. 242-248
    • Kang, J.C.1
  • 18
    • 0242351615 scopus 로고    scopus 로고
    • Toll-like receptors and their signaling mechanisms
    • Akira,S. et al. (2003) Toll-like receptors and their signaling mechanisms. Scand. J. Infect. Dis., 35, 555-562.
    • (2003) Scand. J. Infect. Dis. , vol.35 , pp. 555-562
    • Akira, S.1
  • 19
    • 78649696296 scopus 로고    scopus 로고
    • Endogenous toll-like receptor ligands and their biological significance
    • Yu,L. et al. (2010) Endogenous toll-like receptor ligands and their biological significance. J. Cell. Mol. Med., 14, 2592-2603.
    • (2010) J. Cell. Mol. Med. , vol.14 , pp. 2592-2603
    • Yu, L.1
  • 20
    • 78349255916 scopus 로고    scopus 로고
    • Toll-like receptor signaling pathways-therapeutic opportunities
    • Zhu,J. et al. (2010) Toll-like receptor signaling pathways-therapeutic opportunities. Mediators Inflamm., 2010, 781235.
    • (2010) Mediators Inflamm. , vol.2010 , pp. 781235
    • Zhu, J.1
  • 21
    • 33845752914 scopus 로고    scopus 로고
    • p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
    • Saccani,A. et al. (2006) p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res., 66, 11432-11440.
    • (2006) Cancer Res. , vol.66 , pp. 11432-11440
    • Saccani, A.1
  • 22
    • 2442635429 scopus 로고    scopus 로고
    • Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses
    • Mathur,R.K. et al. (2004) Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses. Nat. Med., 10, 540-544.
    • (2004) Nat. Med. , vol.10 , pp. 540-544
    • Mathur, R.K.1
  • 23
    • 0038346613 scopus 로고    scopus 로고
    • Suppression of interleukin-12 production through endogenously secreted interleukin-10 in activated dendritic cells: involvement of activation of extracellular signal-regulated protein kinase
    • Xia,C.Q. et al. (2003) Suppression of interleukin-12 production through endogenously secreted interleukin-10 in activated dendritic cells: involvement of activation of extracellular signal-regulated protein kinase. Scand. J. Immunol., 58, 23-32.
    • (2003) Scand. J. Immunol. , vol.58 , pp. 23-32
    • Xia, C.Q.1
  • 24
    • 30744448978 scopus 로고    scopus 로고
    • Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with Helicobacter hepaticus
    • Tomczak,M.F. et al. (2006) Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with Helicobacter hepaticus. J. Immunol., 176, 1244-1251.
    • (2006) J. Immunol. , vol.176 , pp. 1244-1251
    • Tomczak, M.F.1
  • 25
    • 21244502077 scopus 로고    scopus 로고
    • ERK activation following macrophage FcgammaR ligation leads to chromatin modifications at the IL-10 locus
    • Lucas,M. et al. (2005) ERK activation following macrophage FcgammaR ligation leads to chromatin modifications at the IL-10 locus. J. Immunol., 175, 469-477.
    • (2005) J. Immunol. , vol.175 , pp. 469-477
    • Lucas, M.1
  • 26
    • 77950290067 scopus 로고    scopus 로고
    • Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression
    • Zacharioudaki,V. et al. (2009) Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression. J. Immunol., 182, 6444-6451.
    • (2009) J. Immunol. , vol.182 , pp. 6444-6451
    • Zacharioudaki, V.1
  • 27
    • 0037178785 scopus 로고    scopus 로고
    • IRAK-M is a negative regulator of toll-like receptor signaling
    • Kobayashi,K. et al. (2002) IRAK-M is a negative regulator of toll-like receptor signaling. Cell, 110, 191-202.
    • (2002) Cell , vol.110 , pp. 191-202
    • Kobayashi, K.1
  • 28
    • 33344460032 scopus 로고    scopus 로고
    • A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation)
    • Biswas,S.K. et al. (2006) A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). Blood, 107, 2112-2122.
    • (2006) Blood , vol.107 , pp. 2112-2122
    • Biswas, S.K.1
  • 29
    • 58649119388 scopus 로고    scopus 로고
    • Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment
    • Kortylewski,M. et al. (2009) Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment. Cancer Cell, 15, 114-123.
    • (2009) Cancer Cell , vol.15 , pp. 114-123
    • Kortylewski, M.1
  • 30
    • 34547960734 scopus 로고    scopus 로고
    • Analysis of gene expression in the tumor-associated macrophage
    • Duff,M.D. et al. (2007) Analysis of gene expression in the tumor-associated macrophage. J. Surg. Res., 142, 119-128.
    • (2007) J. Surg. Res. , vol.142 , pp. 119-128
    • Duff, M.D.1
  • 31
    • 0026563696 scopus 로고
    • Macrophage inflammatory protein 1 modulates macrophage function
    • Fahey,T.J. et al. (1992) Macrophage inflammatory protein 1 modulates macrophage function. J. Immunol., 148, 2764-2769.
    • (1992) J. Immunol. , vol.148 , pp. 2764-2769
    • Fahey, T.J.1
  • 32
    • 0027526348 scopus 로고
    • Protein kinase C isotypes and signal-transduction in human neutrophils: selective substrate specificity of calcium-dependent beta-PKC and novel calcium-independent nPKC
    • Majumdar,S. et al. (1993) Protein kinase C isotypes and signal-transduction in human neutrophils: selective substrate specificity of calcium-dependent beta-PKC and novel calcium-independent nPKC. Biochim. Biophys. Acta, 1176, 276-286.
    • (1993) Biochim. Biophys. Acta , vol.1176 , pp. 276-286
    • Majumdar, S.1
  • 33
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
    • Towbin,H. et al. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl Acad. Sci. USA, 76, 4350-4354.
    • (1979) Proc. Natl Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1
  • 34
    • 71149121322 scopus 로고    scopus 로고
    • LMP1-augmented kappa intron enhancer activity contributes to upregulation expression of Ig kappa light chain via NF-kappaB and AP-1 pathways in nasopharyngeal carcinoma cells
    • Liu,H. et al. (2009) LMP1-augmented kappa intron enhancer activity contributes to upregulation expression of Ig kappa light chain via NF-kappaB and AP-1 pathways in nasopharyngeal carcinoma cells. Mol. Cancer, 8, 92.
    • (2009) Mol. Cancer , vol.8 , pp. 92
    • Liu, H.1
  • 35
    • 0020448709 scopus 로고
    • Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids
    • Green,L.C. et al. (1982) Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal. Biochem., 126, 131-138.
    • (1982) Anal. Biochem. , vol.126 , pp. 131-138
    • Green, L.C.1
  • 36
    • 0023277545 scopus 로고
    • A single step method of RNA isolation by guanidium thiocyanate-phenol-chloroform extraction
    • Chomezynasky,P. et al. (1987) A single step method of RNA isolation by guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomezynasky, P.1
  • 37
  • 38
    • 79957627922 scopus 로고    scopus 로고
    • TGF-β-induced IRAK-M expression in tumorassociated macrophages regulates lung tumor growth
    • Standiford,T.J. et al. (2011) TGF-β-induced IRAK-M expression in tumorassociated macrophages regulates lung tumor growth. Oncogene, 30, 2475-2484.
    • (2011) Oncogene , vol.30 , pp. 2475-2484
    • Standiford, T.J.1
  • 39
    • 0032740614 scopus 로고    scopus 로고
    • Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase
    • Feng,G.J. et al. (1999) Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. J. Immunol., 163, 6403-6412.
    • (1999) J. Immunol. , vol.163 , pp. 6403-6412
    • Feng, G.J.1
  • 40
    • 34249329607 scopus 로고    scopus 로고
    • Sensitivity of TLR4- and -7-induced NF kappa B1 p105-TPL2-ERK pathway to TNF-receptor-associated-factor-6 revealed by RNAi in mouse macrophages
    • Loniewski,K.J. et al. (2007) Sensitivity of TLR4- and -7-induced NF kappa B1 p105-TPL2-ERK pathway to TNF-receptor-associated-factor-6 revealed by RNAi in mouse macrophages. Mol. Immunol., 44, 3715-3723.
    • (2007) Mol. Immunol. , vol.44 , pp. 3715-3723
    • Loniewski, K.J.1
  • 41
    • 78649259701 scopus 로고    scopus 로고
    • Toll-like receptor 3: involvement with exogenous and endogenous RNA
    • Amarante,M.K. et al. (2010) Toll-like receptor 3: involvement with exogenous and endogenous RNA. Int. Rev. Immunol., 29, 557-573.
    • (2010) Int. Rev. Immunol. , vol.29 , pp. 557-573
    • Amarante, M.K.1
  • 42
    • 77954005130 scopus 로고    scopus 로고
    • Endogenous ligands of TLR2 and TLR4: agonists or assistants?
    • Erridge,C. (2010) Endogenous ligands of TLR2 and TLR4: agonists or assistants? J. Leukoc. Biol., 87, 989-999.
    • (2010) J Leukoc. Biol. , vol.87 , pp. 989-999
    • Erridge, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.