3′-Chloro-5,7-dimethoxyisoflavone inhibits TNFα-induced CXCL10 gene transcription by suppressing the NF-κB pathway in HCT116 human colon cancer cells

International Immunopharmacology

Volumn 11, Issue 12, 2011, Pages 2104-2111

  Shin, Soon Young ^a,b   Hyun, Jiye ^b   Lim, Yoongho ^b   Lee, Young Han ^a,b  

^a Konkuk University Hospital   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

3 Chloro 5,7 dimethoxyisoflavone; CXCL10; NF B; TNF

Indexed keywords

3' CHLORO 5,7 DIMETHOXYISOFLAVONE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOFLAVONE DERIVATIVE; UNCLASSIFIED DRUG; 3'-CHLORO-5,7-DIMETHOXYISOFLAVONE; ANTINEOPLASTIC AGENT; CXCL10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BINDING SITE; CELL MOTILITY; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INFLAMMATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; COLON TUMOR; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IMMUNOLOGY; PHOSPHORYLATION;

ANTINEOPLASTIC AGENTS; BINDING SITES; CHEMOKINE CXCL10; COLONIC NEOPLASMS; HCT116 CELLS; HUMANS; ISOFLAVONES; NF-KAPPA B; PHOSPHORYLATION; POINT MUTATION; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 81855166650     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.09.003     Document Type: Article

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