Antidiabetogenic and cytoprotective effect of butanolic extract of Ranunculus repens L. and quercetin on an experimental model of alloxanic diabetes;Effet antidiabétogène et cytoprotecteur de l'extrait butanolique de Ranunculus repens L. et de la quercétine sur un modèle expérimental de diabète alloxanique

Phytotherapie

Volumn 9, Issue 5, 2011, Pages 274-282

  Kebieche M ^a   Lakroun, Z ^a   Mraihi Z ^b   Soulimani, R ^c  

^a UNIVERSITY OF JIJEL   (Algeria)

^b Universite Mentouri Constantine   (Algeria)

^c CEMAGREF   (France)

Author keywords

Alloxan; Antidiabetogenic effect; Flavonoids; Oxidant stress; Quercetin; Ranunculus repens L.

Indexed keywords

ANTIDIABETIC AGENT; BUTANOL; GLUCOSE; PHENOL DERIVATIVE; PLANT EXTRACT; QUERCETIN; RANUNCULUS REPENS EXTRACT; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CYTOSOL; DRUG ACTIVITY; DRUG EFFECT; GLUCOSE BLOOD LEVEL; INSULIN RELEASE; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PANCREAS CELL; RAT;

EID: 81855166601     PISSN: 16248597     EISSN: 17652847     Source Type: Journal    
DOI: 10.1007/s10298-011-0651-4     Document Type: Article

References (52)

1. T. El-Alfy Abir A.E. Ahmed Amany J. Fatani Amal 2005 Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats Pharmacol Res 52 264 270 15925517 1:STN:280:DC%2BD2MzntVCqsA%3D%3D
2. A.A. Adeneye O.P. Ajagbonna O.W. Ayodele 2007 Hypoglycemic and antidiabetic activities on the stem bark aqueous and ethanol extracts of Musangacecropioides in normal and alloxan-induced diabetic rats Fitoterapia 78 502 505 17651918 1:STN:280:DC%2BD2snktFWjtg%3D%3D (Pubitemid 350001234)
3. I.B. Afanas'ev I. Dorozhko A.V. Brodskii, et al. 1989 Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation Biochem Pharmacol 38 1763 1769 2735934 (Pubitemid 19138525)
4. A. Al-Achi 2005 Herbs that affect blood glucose levels Women's Health in Primary Care 8 7 325 330
5. T. Bahorun B. Gressier F. Trotin, et al. 1996 Oxygen species scavenging activity of phenolic extract from Hawthorn fresh plant organs and pharmaceutical preparations Arzneim-Forsch/Drug Res 46 11 1086 1089 1:CAS:528: DyaK28XntVGnsbk%3D (Pubitemid 26391747)
6. J.W. Baynes 1991 Role of oxidative stress in development of complications in diabetes Diabetes 40 405 412 2010041 1:CAS:528:DyaK3MXktVGqur8%3D
7. C. Beauchamp I. Fridovich 1971 Assay of superoxide dismutase Anal Biochem 44 276 287 4943714 1:CAS:528:DyaE38XjtFKhsg%3D%3D
8. W. Bors W. Heller C. Michel M. Saran 1990 Flavonoids as antioxidants: determination of radical-scavenging efficiencies Methods Enzymol 186 343 355 2172711 1:CAS:528:DyaK3MXksVGmtbs%3D (Pubitemid 20279976)
9. T.M. Bray W.J. Bettger 1990 The physiological role of zinc as an antioxidant Free Radic Biol Med 8 281 291 2187766 1:CAS:528:DyaK3MXks1yqtbg%3D
10. e édition, pp. 250-270
11. Butler LG (1989) Sorghum polyphenols. In: Cheeke PR (ed) Toxicant of plant origin. CRC Press, New York, vol 4, chap 5, pp. 95-121
12. Clairborne A (1985) Catalase activity. In: Greenwald RA (ed) CRC handbook of methods for oxygen radical research. CRC Press, Boca Raton, FL, pp. 283-284
13. O. Coskun M. Kanter A. Korkmaz S. Oter 2005 Quercetin, flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and cell damage in rat pancreas Pharmacol Res 51 117 123 15629256 1:CAS:528:DC%2BD2MXjvFGq (Pubitemid 40040541)
14. W.R. Cunha G.M. Arantes D.S. Ferreira, et al. 2008 Hypoglicemic effect of Leandra lacunosa in normal and alloxan-induced diabetic rats Fitoterapia 79 356 360 18538949 1:CAS:528:DC%2BD1cXosVOnsbY%3D
15. S.P. Dhanabal M.K. Mohan Maruga Raja M. Ramanathan B. Suresh 2007 A hypoglycemic activity of Nymphaea stellata leaves ethanolic extractin alloxan induced diabetic rats Fitoterapia 78 288 291 17498889 1:STN:280: DC%2BD2szhs1Omtw%3D%3D (Pubitemid 46779147)
16. M.A. El-Missiry A.M. El Gindy 2000 Amelioration of alloxan induced diabetes mellitus and oxidative stress in rats by oil of Erucasativa seeds Ann Nutr Metab 44 97 100 11053894 1:CAS:528:DC%2BD3cXnslGlu7k%3D
17. G.L. Ellman 1959 Plasma antioxidants Arch Biochem Biophysics 82 70 77 1:CAS:528:DyaG1MXotl2ksA%3D%3D
18. J.L. Evans I.D. Goldfine B.A. Maddux G.M. Grodsky 2002 Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes Endocr Rev 23 599 622 12372842 1:CAS:528:DC%2BD38XosVejsbg%3D (Pubitemid 35191625)
19. H.D. Graham S. Szabo 1992 Experimental gastric mucosal injury: laboratory models reveal mechanisms of pathogenesis and new therapeutic strategies FASEB J 6 825 832
20. I. Huk V. Brokovich J. Nanobashvili, et al. 1998 Bioflavonoid quercetin scavenger superoxide and increases nitric oxide concentration in ischemia-reperfusion injury: an experimental study Brit J Surg 85 1080 1085 9718001 1:STN:280:DyaK1czot1Wjsw%3D%3D (Pubitemid 28360771)
21. Y. Ihara S. Toyokuni K. Uchida, et al. 1999 Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes Diabetes 48 927 932 10102716 1:CAS:528:DyaK1MXitFCqtbc%3D (Pubitemid 29153099)
22. Inal ME, Akgun A, Kahraman A (2002) Radioprotective effects of exogenous glutathione against whole-body gamma-ray irradiation: age and gender-related changes in malondialdehyde levels, superoxide dismutase and catalase activities in rat liver. Methods Find Exp Clin Pharmacol 209-212 (Pubitemid 34606350)
23. M. Iqbal D.S. Som O. Yasumasa, et al. 2003 Dietary supplementation of curcumin enhances antioxidant and phase II metabolising enzymes in male mice: possible role in protection against chemical carcinogenesis and toxicity Pharmacol Toxicol 92 33 38 12710595 1:CAS:528:DC%2BD3sXitlCrurc%3D (Pubitemid 36238075)
24. L. Jin H.Y. Xue L.J. Jin, et al. 2008 Antioxidant and pancreas-protective effect of aucubin on rats with streptozotocin-induced diabetes Eur J Pharmacol 582 162 167 18230397 1:CAS:528:DC%2BD1cXitVeitLo%3D
25. K. Kamiya W. Hamabe S. Harada, et al. 2008 Chemical constituents of Morinda citrifolia roots exhibit hypoglycemic effects in streptozotocin-induced diabetic mice Biol Pharm Bull 31 935 938 18451522 1:CAS:528:DC%2BD1cXotF2mt7s%3D (Pubitemid 351732000)
26. M. Kanter I. Meral S. Dede, et al. 2003 Effects of Nigella sativa L. and Urtica dioica L. on lipid peroxidation, antioxidant enzyme systems and some liver enzymes in CCl4-treated rats J Vet Med A Physiol Pathol Clin Med 50 264 268 14567515 1:STN:280:DC%2BD3svptVSrsQ%3D%3D (Pubitemid 41743024)
27. M. Kebièche Z. Lakroun M. Lahouel, et al. 2009 Evaluation of epirubicin-induced acute oxidative stres toxicity in rat liver cells and mitochindria, and the prevention of toxicity through quercetin administration Exper Toxicol Pathol 61 161 167
28. M.J. Laughton P.J. Evans M.A. Moroney, et al. 1991 Inhibition of mammalian 5-lipoxygenase and cyclo-oxygenase by flavonoids and phenolic dietary additives. Relationship to antioxidant activity and to iron ion-reducing ability Biochem Pharmacol 42 1673 1681 1656994 1:CAS:528:DyaK38Xjsl0%3D
29. S. Lenzen J. Drinkgern M. Tiedge 1996 Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues Free Radic Biol Med 20 463 466 8720919 1:CAS:528:DyaK28XhvVWitLw%3D (Pubitemid 26077870)
30. S. Lenzen R. Munday 1991 Thiol group reactivity, hydrophilicity and stability of alloxan, its reduction products and its N-methyl derivatives and a comparison with ninhydrin Biochem Pharmacol 42 1385 1391 1930261 1:CAS:528:DyaK3MXms12ru7c%3D
31. M. Lopez-Lazaro C. Martin-Cordero M.J. Ayuso 2000 Two new flavonol glycosides as DNA topoisomerase I poison Z Naturfresch 55 11-12 898 902 1:CAS:528:DC%2BD3MXltFajuw%3D%3D (Pubitemid 32111223)
32. O.H. Lowry N.J. Rosegrough A.L. Farr R.J. Randall 1951 Protein measurement with the folin phenol reagent J Biol Chem 193 265 275 14907713 1:CAS:528:DyaG38XhsVyrsw%3D%3D
33. Marfak A (2003) Radiolyse gamma des flavonoïdes: étude de leur réactivité avec les radicaux issus des alcools: formation des depsides. Thèse de doctorat de l'université de Limoges, pp. 24-42
34. Markham KR (1982) Technics of flavonoids identification. Academic Press (London); chap 1 et 2: 1-113
35. E. Middleton Jr 1998 Effect of plant flavonoids on immune and inflammatory cell function Adv Exp Med Biol 439 175 182 9781303 1:CAS:528:DyaK1cXmvFKms78%3D (Pubitemid 28429016)
36. D. Morin H. Thiery M. Spedding J.P. Tillement 2001 Mitochondria as target for antiischemic drugs J Physiol Pharmacol 13 22 67
37. H. Nogichi 2007 Stem cells for the treatment of diabetes Endocr J 54 7 16
38. L.W. Oberley 1988 Free radicals and diabetes Free Radic Biol Med 5 113 124 3075947 1:CAS:528:DyaL1cXlt1Kltr4%3D (Pubitemid 18263730)
39. H. Ohkawa N. Ohishi K. Yagi 1979 Assay of lipid peroxides in animal tissue by thiobarbituric reaction Analytical Biochem 95 351 358 1:CAS:528:DyaE1MXksFaisbk%3D (Pubitemid 9194347)
40. P. Pavana S. Monoharan G.L. Renju S. Sethupathy 2007 Antihyperglycemic and antihyperlipidemic effects of Tephrosia purpurea leaf extract in streptozotocin induced diabetic rats J Environ Biol 28 833 837 18405121 1:STN:280:DC%2BD1c3ks1Kiuw%3D%3D (Pubitemid 47605742)
41. M. Prasenjit S. Mahua C.S. Parames 2009 Protective role of arjunolic acid in response to streptozotocin-induced type-I diabetes via the mitochondrial dependent and independent pathways Toxicology 257 53 63
42. K.A. Pritchard Jr S.T. Patel C.W. Karpen, et al. 1986 Triglyceride-lowering effect of dietary vitamin E in streptozocin-induced diabetic rats. Increased lipoprotein lipase activity in livers of diabetic rats fed high dietary vitamin E Diabetes 35 278 281 3512338 1:CAS:528: DyaL28XitVGqtrs%3D (Pubitemid 16136995)
43. G. Quinlan J. Gutteridege 1988 Hydroxyradical generation by the tetracycline antibodies with free radical damage to DNA, lipids, carbohydrates carbohydratesin the presence of iron and copper salts Biol Med 5 341 348 1:CAS:528:DyaL1MXhvVWksQ%3D%3D (Pubitemid 19024284)
44. M.C. Sabu R. Kuttan 2002 Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property J Ethnopharmacol 81 155 160 12065146 1:STN:280:DC%2BD38nlsFGnsw%3D%3D (Pubitemid 34628497)
45. T. Sakurai S. Tsuchiya 1988 Superoxide productin from nonenzymatically glycated proteins FEBS Lett 236 406 410 2842191 1:CAS:528:DyaL1MXjtV2j
46. Servais S (2004) Altération mitochondriale et stress oxydant pulmonaire en réponse à l'ozone: effets de l'âge et d'une supplémentation en oméga-3. Thèse de doctorat, université Claude Bernard-Lyon-I, France, pp. 19-35
47. Singh J, Kakkar P (2009) Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. J Ethnopharmacol doi:10.1016/j.jep.02.038
48. T. Szkudelski 2001 The mechanism of alloxan and streptozotocin action in β-cells of the rat pancreas Physiol Res 50 536 546
49. M. Vessal M. Hemmati M. Vasie 2003 Antidiabetic effects of quercetinin streptozocin-induced diabetic rats Comp Biochem Physiol C Toxicol Pharmacol 135 357 364 (Pubitemid 36962949)
50. A. Wahllandir S. Soboll H. Sies, et al. 1979 FEBES Lett 97 138 140
51. S.P. Wolff 1993 Diabetes mellitus and free radical. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications Br Med Bull 49 643 649
52. S.P. Wolff Z.Y. Jiang J.V. Hunt 1991 Protein glycation and oxidative stress in diabetes mellitus and ageing Free Radic Biol Med 10 339 352 1855674 1:CAS:528:DyaK3MXktVKjsrY%3D (Pubitemid 121003905)