메뉴 건너뛰기




Volumn 12, Issue 18, 2011, Pages 2817-2831

Could the underestimation of bipolarity obstruct the search for novel antidepressant drugs?

Author keywords

Antidepressants; Bipolar disorder (BD); Bipolarity; Depression; Development; Major depressive disorder (MDD); Underestimation

Indexed keywords

1 (3,4 DICHLOROPHENYL) 3 AZABICYCLO[3.1.0]HEXANE; 1 [1 (4 CHLOROPHENYL)CYCLOBUTYL] 3 METHYLBUTANAMINE; 11BETA (1,3 BENZODIOXOL 5 YL) 17BETA HYDROXY 17ALPHA (1 PROPYNYL)ESTRA 4,9 DIEN 3 ONE; 3 (3,4 DICHLOROPHENYL) 2 (METHOXYMETHYL) 8 AZABICYCLO[3.2.1]OCTANE; 3 (6 DIMETHYLAMINO 4 METHYL 3 PYRIDINYL) 7 DIPROPYLAMINO 2,5 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDINE; 4 (2 CHLORO 4 METHOXY 5 METHYLPHENYL) N [2 CYCLOPROPYL 1 (3 FLUORO 4 METHYLPHENYL)ETHYL] 5 METHYL N (2 PROPYNYL) 2 THIAZOLAMINE; 6 (4 ETHYNYLPHENYL) 1,2,3,5,6,10B HEXAHYDROPYRROLO[2,1 A]ISOQUINOLINE; AGOMELATINE; AMIBEGRON; ANTIDEPRESSANT AGENT; CP 316311; CUTAMESINE; EMICERFONT; GSK 586529; JNJ 19567470; JNJ 792476; LU AA24530; LU AA34893; LU AA37096; MIFEPRISTONE; MONOAMINE; NELIVAPTAN; NS 2360; ONO 233M; ORG 26576; PEXACERFONT; SCH 900635; SSR 126374; SSR 411298; TESOFENSINE; TS 041; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERUCERFONT;

EID: 81855166091     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2011.632366     Document Type: Review
Times cited : (20)

References (152)
  • 1
    • 84855199246 scopus 로고    scopus 로고
    • TalmudChapter I. Available from:
    • Talmud. Tractate Derech Eretz Zuta, Chapter I. Available from: http://www.jewishvirtuallibrary.org/ jsource/Talmud/derecheretzruta1.html
    • Tractate Derech Eretz Zuta
  • 2
    • 40649108861 scopus 로고    scopus 로고
    • Suicide risk and depression
    • Terra JL. Suicide risk and depression. Rev Prat 2008;12(4):385-8
    • (2008) Rev. Prat. , vol.12 , Issue.4 , pp. 385-388
    • Terra, J.L.1
  • 3
  • 4
    • 0037831023 scopus 로고    scopus 로고
    • The epidemiology of major depressive disorder: Results from the national comorbidity survey replication ncs-r
    • Kessler RC, Berglund P, Demler O, et al. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R).JAMA 2003;289(23):3095-105
    • (2003) JAMA , vol.289 , Issue.23 , pp. 3095-3105
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3
  • 5
    • 0004500264 scopus 로고
    • Anxiety and depressive states treated with isonicotinyl hydrazide isoniazid
    • Salzer HM, Lurie ML. Anxiety and depressive states treated with isonicotinyl hydrazide (isoniazid).AMA Arch Neurol Psychiatry 1953;70(3):317-24
    • (1953) AMA Arch. Neurol. Psychiatry , vol.70 , Issue.3 , pp. 317-324
    • Salzer, H.M.1    Lurie, M.L.2
  • 6
    • 33644990706 scopus 로고
    • Iproniazid marsilid: Its use in office treatment of depression
    • Scanlon WG, White WM. Iproniazid (marsilid): its use in office treatment of depression. Am J Psychiatry 1958;114(11):1036-7
    • (1958) Am. J. Psychiatry , vol.114 , Issue.11 , pp. 1036-1037
    • Scanlon, W.G.1    White, W.M.2
  • 7
    • 0000876391 scopus 로고
    • The treatment of depressive states with G 22355 imipramine hydrochloride
    • Kuhn R. The treatment of depressive states with G 22355 (imipramine hydrochloride).Am J Psychiatry 1958;115(5):459-64
    • (1958) Am. J. Psychiatry , vol.115 , Issue.5 , pp. 459-464
    • Kuhn, R.1
  • 8
    • 0033021862 scopus 로고    scopus 로고
    • The three faces of the antidepressants: A critical commentary on the clinical-economic context of diagnosis
    • Healy D. The three faces of the antidepressants: a critical commentary on the clinical-economic context of diagnosis. J Nerv Ment Dis 1999;187(3):174-80
    • (1999) J Nerv. Ment. Dis. , vol.187 , Issue.3 , pp. 174-180
    • Healy, D.1
  • 9
    • 0024046016 scopus 로고
    • Fluoxetine A new antidepressant
    • Poe TE. Fluoxetine. A new antidepressant. N C Med J 1988;49(7):391-2
    • (1988) N. C. Med. J. , vol.49 , Issue.7 , pp. 391-392
    • Poe, T.E.1
  • 10
    • 77957596338 scopus 로고    scopus 로고
    • CNS drug development part I: The early period of CNS drugs
    • Preskorn SH. CNS drug development. Part I: the early period of CNS drugs. J Psychiatr Pract 2010;16(5):334-9
    • (2010) J. Psychiatr. Pract. , vol.16 , Issue.5 , pp. 334-339
    • Preskorn, S.H.1
  • 11
    • 0034135847 scopus 로고    scopus 로고
    • Tricyclic antidepressants
    • Hanada K, Umemura S. Tricyclic antidepressants. Nippon Rinsho 2000;58(Suppl 2):633-7
    • (2000) Nippon. Rinsho. , vol.58 , Issue.2 , pp. 633-637
    • Hanada, K.1    Umemura, S.2
  • 13
    • 33750455443 scopus 로고    scopus 로고
    • Drug treatment of depression in the 2000s: An overview of achievements in the last 10 years and future possibilities
    • Baghai TC, Volz HP, Moller HJ. Drug treatment of depression in the 2000s: an overview of achievements in the last 10 years and future possibilities. World J Biol Psychiatry 2006;7(4):198-222
    • (2006) World J.Biol.Psychiatry. , vol.7 , Issue.4 , pp. 198-222
    • Baghai, T.C.1    Volz, H.P.2    Moller, H.J.3
  • 14
    • 2142822259 scopus 로고    scopus 로고
    • Selectivity of antidepressants: From the monoamine hypothesis of depression to the SSRI revolution and beyond
    • Owens MJ. Selectivity of antidepressants: from the monoamine hypothesis of depression to the SSRI revolution and beyond. J Clin Psychiatry 2004;65(Suppl 4):5-10
    • (2004) J. Clin. Psychiatry , vol.65 , Issue.4 , pp. 5-10
    • Owens, M.J.1
  • 15
    • 0011145384 scopus 로고    scopus 로고
    • SSRI antidepressant medications: Adverse effects and tolerability
    • Ferguson JM. SSRI antidepressant medications: adverse effects and tolerability. Prim Care Companion J Clin Psychiatry 2001;3(1):22-7
    • (2001) Prim. Care Companion. J. Clin. Psychiatry , vol.3 , Issue.1 , pp. 22-27
    • Ferguson, J.M.1
  • 18
    • 79960313397 scopus 로고    scopus 로고
    • Strategies to achieve clinical effectiveness: Refining existing therapies and pursuing emerging targets
    • Kennedy SH, Young AH, Blier P. Strategies to achieve clinical effectiveness: refining existing therapies and pursuing emerging targets. J Affect Disord 2011;132(Suppl 1):S21-8
    • (2011) J. Affect. Disord. , vol.132 , Issue.1
    • Kennedy, S.H.1    Young, A.H.2    Blier, P.3
  • 20
    • 77954686636 scopus 로고    scopus 로고
    • The well of novel antidepressants: Running dry
    • Blier P. The well of novel antidepressants: running dry. J Psychiatry Neurosci 2010;35(4):219-20
    • (2010) J. Psychiatry. Neurosci. , vol.35 , Issue.4 , pp. 219-220
    • Blier, P.1
  • 21
    • 79960602647 scopus 로고    scopus 로고
    • Current nosology of treatment resistant depression: A controversy resistant to revision
    • Fornaro M, Giosue P. Current nosology of treatment resistant depression: a controversy resistant to revision. Clin Pract Epidemiol Ment Health 2010;6:20-4
    • (2010) Clin. Pract. Epidemiol. Ment. Health , vol.6 , pp. 20-24
    • Fornaro, M.1    Giosue, P.2
  • 22
    • 70449379106 scopus 로고    scopus 로고
    • Treatment-resistant bipolar depression: Towards a new definition
    • Pacchiarotti I, Mazzarini L, Colom F, et al. Treatment-resistant bipolar depression: towards a new definition. Acta Psychiatr Scand 2009;120(6):429-40
    • (2009) Acta. Psychiatr. Scand. , vol.120 , Issue.6 , pp. 429-440
    • Pacchiarotti, I.1    Mazzarini, L.2    Colom, F.3
  • 23
    • 0000264756 scopus 로고
    • The catecholamine hypothesis of affective disorders: A review of supporting evidence
    • Schildkraut JJ. The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am J Psychiatry 1965;122(5):509-22
    • (1965) Am. J. Psychiatry , vol.122 , Issue.5 , pp. 509-522
    • Schildkraut, J.J.1
  • 24
    • 50549205358 scopus 로고
    • Potentiation of the antidepressive effect of a monoamine-oxidase inhibitor by tryptophan
    • Coppen A, Shaw DM, Farrell JP. Potentiation of the antidepressive effect of a monoamine-oxidase inhibitor by tryptophan. Lancet 1963;1(7272):79-81
    • (1963) Lancet , vol.1 , Issue.7272 , pp. 79-81
    • Coppen, A.1    Shaw, D.M.2    Farrell, J.P.3
  • 25
    • 0015863121 scopus 로고
    • The role of dopamine in depression
    • McClure DJ. The role of dopamine in depression. Can Psychiatr Assoc J 1973;18(4):309012
    • (1973) Can. Psychiatr. Assoc. J. , vol.18 , Issue.4 , pp. 309012
    • McClure, D.J.1
  • 26
    • 0034006802 scopus 로고    scopus 로고
    • History and evolution of the monoamine hypothesis of depression
    • Hirschfeld RM. History and evolution of the monoamine hypothesis of depression. J Clin Psychiatry 2000;61(Suppl 6):4-6
    • (2000) J. Clin. Psychiatry , vol.61 , Issue.6 , pp. 4-6
    • Hirschfeld, R.M.1
  • 27
    • 0016132857 scopus 로고
    • Catecholamines and depression: A physiological theory of depression
    • Kicey CA. Catecholamines and depression: a physiological theory of depression. Am J Nurs 1974;74(11):2018-20
    • (1974) Am. J. Nurs. , vol.74 , Issue.11 , pp. 2018-2020
    • Kicey, C.A.1
  • 28
    • 34547093178 scopus 로고    scopus 로고
    • The other face of depression reduced positive affect: The role of catecholamines in causation and cure
    • Nutt D, Demyttenaere K, Janka Z, et al. The other face of depression, reduced positive affect: the role of catecholamines in causation and cure. J Psychopharmacol 2007;21(5):461-71
    • (2007) J. Psychopharmacol. , vol.21 , Issue.5 , pp. 461-471
    • Nutt, D.1    Demyttenaere, K.2    Janka, Z.3
  • 29
    • 0028196805 scopus 로고
    • Catecholamines in depression: An update
    • Potter WZ, Manji HK. Catecholamines in depression: an update. Clin Chem 1994;40(2):279-87
    • (1994) Clin. Chem. , vol.40 , Issue.2 , pp. 279-287
    • Potter, W.Z.1    Manji, H.K.2
  • 31
    • 33751230174 scopus 로고    scopus 로고
    • The onset of effect for escitalopram and its relevance for the clinical management of depression
    • Wade A, Friis Andersen H. The onset of effect for escitalopram and its relevance for the clinical management of depression. Curr Med Res Opin 2006;22(11):2101-10
    • (2006) Curr. Med. Res. Opin. , vol.22 , Issue.11 , pp. 2101-2110
    • Wade, A.1    Friis Andersen, H.2
  • 32
    • 0019469314 scopus 로고
    • Receptor sensitivity and the mechanism of action of antidepressant treatment implications for the etiology and therapy of depression
    • Charney DS, Menkes DB, Heninger GR. Receptor sensitivity and the mechanism of action of antidepressant treatment. Implications for the etiology and therapy of depression. Arch Gen Psychiatry 1981;38(10):1160-80
    • (1981) Arch. Gen. Psychiatry , vol.38 , Issue.10 , pp. 1160-1180
    • Charney, D.S.1    Menkes, D.B.2    Heninger, G.R.3
  • 33
    • 77954182731 scopus 로고    scopus 로고
    • Classical neurotransmitters and neuropeptides involved in major depression: A review
    • Werner FM, Covenas R. Classical neurotransmitters and neuropeptides involved in major depression: a review. Int J Neurosci 2010;120(7):455-70
    • (2010) Int. J. Neurosci. , vol.120 , Issue.7 , pp. 455-470
    • Werner, F.M.1    Covenas, R.2
  • 34
    • 78649908701 scopus 로고    scopus 로고
    • Depression: A repair response to stress-induced neuronal microdamage that can grade into a chronic neuroinflammatory condition
    • Wager-Smith K, Markou A. Depression: a repair response to stress-induced neuronal microdamage that can grade into a chronic neuroinflammatory condition? Neurosci Biobehav Rev 2011;35(3):742-64
    • (2011) Neurosci. Biobehav. Rev. , vol.35 , Issue.3 , pp. 742-764
    • Wager-Smith, K.1    Markou, A.2
  • 35
    • 0642305520 scopus 로고    scopus 로고
    • Neurotransmitters neurosteroids and neurotrophins: New models of the pathophysiology and treatment of depression
    • Wolkowitz OM, Reus VI. Neurotransmitters, neurosteroids and neurotrophins: new models of the pathophysiology and treatment of depression. World J Biol Psychiatry 2003;4(3):98-102
    • (2003) World J. Biol. Psychiatry. , vol.4 , Issue.3 , pp. 98-102
    • Wolkowitz, O.M.1    Reus, V.I.2
  • 36
    • 79953240356 scopus 로고    scopus 로고
    • Where is the room for improvement in the drug treatment of depression and anxiety
    • Baldwin DS. Where is the room for improvement in the drug treatment of depression and anxiety? Hum Psychopharmacol 2011;26(1):1-3
    • (2011) Hum. Psychopharmacol. , vol.26 , Issue.1 , pp. 1-3
    • Baldwin, D.S.1
  • 37
    • 77952316915 scopus 로고    scopus 로고
    • Antidepressants: Cant live with them cant live without them
    • Nierenberg AA. Antidepressants: can't live with them, can't live without them. CNS Spectr 2010;15(3):146-7
    • (2010) CNS Spectr. , vol.15 , Issue.3 , pp. 146-147
    • Nierenberg, A.A.1
  • 38
    • 77951922417 scopus 로고    scopus 로고
    • The timing of antidepressant effects: A comparison of diverse pharmacological and somatic treatments
    • Machado-Vieira R, et al. The timing of antidepressant effects: a comparison of diverse pharmacological and somatic treatments. Pharmaceuticals 2010;3:19-41
    • (2010) Pharmaceuticals , vol.3 , pp. 19-41
    • Machado-Vieira, R.1
  • 39
    • 0030032338 scopus 로고    scopus 로고
    • Initiation and adaptation: A paradigm for understanding psychotropic drug action
    • Hyman SE, Nestler EJ. Initiation and adaptation: a paradigm for understanding psychotropic drug action. Am J Psychiatry 1996;153(2):151-62
    • (1996) Am. J. Psychiatry , vol.153 , Issue.2 , pp. 151-162
    • Hyman, S.E.1    Nestler, E.J.2
  • 40
    • 46749121905 scopus 로고    scopus 로고
    • Rapid onset of antidepressant action: A new paradigm in the research and treatment of major depressive disorder
    • Machado-Vieira R, Salvadore G, Luckenbaugh DA, et al. Rapid onset of antidepressant action: a new paradigm in the research and treatment of major depressive disorder. J Clin Psychiatry 2008;69(6):946-58
    • (2008) J. Clin. Psychiatry , vol.69 , Issue.6 , pp. 946-958
    • Machado-Vieira, R.1    Salvadore, G.2    Luckenbaugh, D.A.3
  • 41
    • 0037111969 scopus 로고    scopus 로고
    • Timing is everything: Does the robust upregulation of noradrenergically regulated plasticity genes underlie the rapid antidepressant effects of sleep deprivation
    • Payne JL, Quiroz JA, Zarate CA Jr, Manji HK. Timing is everything: does the robust upregulation of noradrenergically regulated plasticity genes underlie the rapid antidepressant effects of sleep deprivation? Biol Psychiatry 2002;52(10):921-6
    • (2002) Biol. Psychiatry , vol.52 , Issue.10 , pp. 921-926
    • Payne, J.L.1    Quiroz, J.A.2    Zarate Jr., C.A.3    Manji, H.K.4
  • 42
    • 0030877266 scopus 로고    scopus 로고
    • Serotonergic autoreceptor blockade in the reduction of antidepressant latency: Personality variables and response to paroxetine and pindolol
    • Tome MB, Cloninger CR, Watson JP, Isaac MT. Serotonergic autoreceptor blockade in the reduction of antidepressant latency: personality variables and response to paroxetine and pindolol. J Affect Disord 1997;44(2-3):101-9
    • (1997) J. Affect. Disord. , vol.44 , Issue.2-3 , pp. 101-109
    • Tome, M.B.1    Cloninger, C.R.2    Watson, J.P.3    Isaac, M.T.4
  • 43
    • 80054991429 scopus 로고    scopus 로고
    • The influence of personality factors on paroxetine response time in patients with major depression
    • KanedazA, Yasui-Furukori N, Nakagami T, et al. The influence of personality factors on paroxetine response time in patients with major depression. J Affect Disord 2011
    • (2011) J. Affect. Disord.
    • Kaneda, A.1    Yasui-Furukori, N.2    Nakagami, T.3
  • 44
    • 0035169180 scopus 로고    scopus 로고
    • Severe depression: Is there a best approach
    • Sonawalla SB, Fava M. Severe depression: is there a best approach? CNS Drugs 2001;15(10):765-76
    • (2001) CNS Drugs , vol.15 , Issue.10 , pp. 765-776
    • Sonawalla, S.B.1    Fava, M.2
  • 45
    • 78549269430 scopus 로고    scopus 로고
    • A systematic updated review on the antidepressant agomelatine focusing on its melatonergic modulation
    • Fornaro M, Prestia D, Colicchio S, Perugi G. A systematic, updated review on the antidepressant agomelatine focusing on its melatonergic modulation. Curr Neuropharmacol 2010;8(3):287-304
    • (2010) Curr. Neuropharmacol. , vol.8 , Issue.3 , pp. 287-304
    • Fornaro, M.1    Prestia, D.2    Colicchio, S.3    Perugi, G.4
  • 46
    • 78751494158 scopus 로고    scopus 로고
    • Inflammatory and neurodegenerative pathways in depression: A new avenue for antidepressant development
    • Catena-Dell'Osso M, Bellantuono C, Consoli G, et al. Inflammatory and neurodegenerative pathways in depression: a new avenue for antidepressant development? Curr Med Chem 2011;18(2):245-55
    • (2011) Curr. Med. Chem. , vol.18 , Issue.2 , pp. 245-255
    • Catena-Dell'Osso, M.1    Bellantuono, C.2    Consoli, G.3
  • 48
    • 22544472682 scopus 로고    scopus 로고
    • Effect of neurokinin-1 receptor antagonists on serotoninergic noradrenergic and hippocampal neurons: Comparison with antidepressant drugs
    • Gobbi G, Blier P. Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: comparison with antidepressant drugs. Peptides 2005;26(8):1383-93
    • (2005) Peptides , vol.26 , Issue.8 , pp. 1383-1393
    • Gobbi, G.1    Blier, P.2
  • 49
    • 3042611638 scopus 로고    scopus 로고
    • Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: Relevance to the antidepressant/anxiolytic response
    • Blier P, Gobbi G, Haddjeri N, et al. Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response. J Psychiatry Neurosci 2004;29(3):208-18
    • (2004) J. Psychiatry. Neurosci. , vol.29 , Issue.3 , pp. 208-2018
    • Blier, P.1    Gobbi, G.2    Haddjeri, N.3
  • 50
    • 67549098436 scopus 로고    scopus 로고
    • Nicotinic modulation of synaptic transmission and plasticity in cortico-limbic circuits
    • Mansvelder HD, Mertz M, Role LW. Nicotinic modulation of synaptic transmission and plasticity in cortico-limbic circuits. Semin Cell Dev Biol 2009;20(4):432-40
    • (2009) Semin. Cell Dev. Biol. , vol.20 , Issue.4 , pp. 432-440
    • Mansvelder, H.D.1    Mertz, M.2    Role, L.W.3
  • 52
    • 84896771996 scopus 로고    scopus 로고
    • State of the art the impact of classification on psychopharmacology and biological psychiatry
    • Van Praag HM. State of the art. The impact of classification on psychopharmacology and biological psychiatry. Dialogues Clin Neurosci 2003;1:141-9
    • (2003) Dialogues. Clin. Neurosci. , vol.1 , pp. 141-149
    • Van Praag, H.M.1
  • 54
    • 33746372423 scopus 로고    scopus 로고
    • Rating sales in depression: Limitations and pitfalls
    • Bech P. Rating sales in depression: limitations and pitfalls. Dialogues Clin Neurosci 2006;8(2):207-15
    • (2006) Dialogues. Clin. Neurosci. , vol.8 , Issue.2 , pp. 207-215
    • Bech, P.1
  • 55
    • 33746346713 scopus 로고    scopus 로고
    • Various forms of depression
    • Benazzi F. Various forms of depression. Dialogues Clin Neurosci 2006;8(2):151-61
    • (2006) Dialogues. Clin. Neurosci. , vol.8 , Issue.2 , pp. 151-161
    • Benazzi, F.1
  • 56
    • 0037986382 scopus 로고    scopus 로고
    • Background and rationale for the sequenced treatment alternatives to relieve depression STAR. *D study
    • x
    • Fava M, Rush AJ, Trivedi MH, et al. Background and rationale for the sequenced treatment alternatives to relieve depression (STAR.*D) study. Psychiatr Clin North Am 2003;26(2):457-94, x
    • (2003) Psychiatr. Clin. North Am. , vol.26 , Issue.2 , pp. 457-494
    • Fava, M.1    Rush, A.J.2    Trivedi, M.H.3
  • 57
    • 67650135637 scopus 로고    scopus 로고
    • Results of the STAR. *D study: Implications for clinicians and drug developers
    • Preskorn SH. Results of the STAR. *D study: implications for clinicians and drug developers. J Psychiatr Pract 2009;15(1):45-9
    • (2009) J. Psychiatr. Pract. , vol.15 , Issue.1 , pp. 45-49
    • Preskorn, S.H.1
  • 58
    • 79958261494 scopus 로고    scopus 로고
    • Examination of the utility of psychotherapy for patients with treatment resistant depression: A systematic review
    • Trivedi RB, Nieuwsma JA, Williams JW Jr. Examination of the utility of psychotherapy for patients with treatment resistant depression: a systematic review. J Gen Intern Med 2011;26(6):643-50
    • (2011) J. Gen. Intern. Med. , vol.26 , Issue.6 , pp. 643-650
    • Trivedi, R.B.1    Nieuwsma, J.A.2    Williams Jr., J.W.3
  • 59
    • 33749049165 scopus 로고    scopus 로고
    • A comparison of lithium and T 3 augmentation following two failed medication treatments for depression: A STAR. *D report
    • quiz 1665
    • Nierenberg AA, Fava M, Trivedi MH, et al. A comparison of lithium and T(3) augmentation following two failed medication treatments for depression: a STAR. *D report. Am J Psychiatry 2006;163(9):1519-30; quiz 1665
    • (2006) Am. J. Psychiatry , vol.163 , Issue.9 , pp. 1519-1530
    • Nierenberg, A.A.1    Fava, M.2    Trivedi, M.H.3
  • 60
    • 65649151698 scopus 로고    scopus 로고
    • Pharmacologic and therapeutic strategies in treatment-resistant depression introduction and clinical presentations
    • O'Reardon JP. Pharmacologic and therapeutic strategies in treatment-resistant depression. Introduction and clinical presentations. CNS Spectr 2009;14(3 Suppl 4):4-6
    • (2009) CNS Spectr. , vol.14 , Issue.3-4 , pp. 4-6
    • O'Reardon, J.P.1
  • 61
    • 69949087539 scopus 로고    scopus 로고
    • Atypical antipsychotic augmentation in major depressive disorder: A meta-analysis of placebo-controlled randomized trials
    • Nelson JC, Papakostas GI. Atypical antipsychotic augmentation in major depressive disorder: a meta-analysis of placebo-controlled randomized trials. Am J Psychiatry 2009;166(9):980-91
    • (2009) Am. J. Psychiatry , vol.166 , Issue.9 , pp. 980-991
    • Nelson, J.C.1    Papakostas, G.I.2
  • 62
    • 78649515965 scopus 로고    scopus 로고
    • Therapeutic potential of new second generation antipsychotics for major depressive disorder
    • McElroy SL, Guerdjikova A, Mori N, Keck PE Jr. Therapeutic potential of new second generation antipsychotics for major depressive disorder. Expert Opin Investig Drugs 2010;19(12):1527-44
    • (2010) Expert. Opin. Investig. Drugs. , vol.19 , Issue.12 , pp. 1527-1544
    • McElroy, S.L.1    Guerdjikova, A.2    Mori, N.3    Keck Jr., P.E.4
  • 63
    • 77951058334 scopus 로고    scopus 로고
    • Olanzapine/fluoxetine combination in patients with treatment-resistant depression: Rapid onset of therapeutic response and its predictive value for subsequent overall response in a pooled analysis of 5 studies
    • Tohen M, Case M, Trivedi MH, et al. Olanzapine/fluoxetine combination in patients with treatment-resistant depression: rapid onset of therapeutic response and its predictive value for subsequent overall response in a pooled analysis of 5 studies. J Clin Psychiatry 2010;71(4):451-62
    • (2010) J. Clin. Psychiatry , vol.71 , Issue.4 , pp. 451-462
    • Tohen, M.1    Case, M.2    Trivedi, M.H.3
  • 64
    • 33646490701 scopus 로고    scopus 로고
    • Antidepressant efficacy of olanzapine as monotherapy in major depressive disorder without psychosis: A pilot study
    • Mathews J, Garcia KS, Mintun MA, Sheline YI. Antidepressant efficacy of olanzapine as monotherapy in major depressive disorder, without psychosis: a pilot study. Psychiatry Res 2006;146(2):149-55
    • (2006) Psychiatry Res. , vol.146 , Issue.2 , pp. 149-155
    • Mathews, J.1    Garcia, K.S.2    Mintun, M.A.3    Sheline, Y.I.4
  • 66
    • 79953741102 scopus 로고    scopus 로고
    • Association between bipolar spectrum features and treatment outcomes in outpatients with major depressive disorder
    • Perlis RH, Uher R, Ostacher M, et al. Association between bipolar spectrum features and treatment outcomes in outpatients with major depressive disorder. Arch Gen Psychiatry 2011;68(4):351-60
    • (2011) Arch. Gen. Psychiatry , vol.68 , Issue.4 , pp. 351-360
    • Perlis, R.H.1    Uher, R.2    Ostacher, M.3
  • 67
    • 0038054362 scopus 로고    scopus 로고
    • Rationale design and methods of the systematic treatment enhancement program for bipolar disorder STEP-BD
    • Sachs GS, Thase ME, Otto MW, et al. Rationale, design, and methods of the systematic treatment enhancement program for bipolar disorder STEP-BD).Biol Psychiatry 2003;53(11):1028-42
    • (2003) Biol. Psychiatry , vol.53 , Issue.11 , pp. 1028-1042
    • Sachs, G.S.1    Thase, M.E.2    Otto, M.W.3
  • 68
    • 56349103640 scopus 로고    scopus 로고
    • Why antidepressants are not antidepressants: STEP-BD STAR. * D and the return of neurotic depression
    • Ghaemi SN. Why antidepressants are not antidepressants: STEP-BD, STAR. *D, and the return of neurotic depression. Bipolar Disord 2008;10(8):957-68
    • (2008) Bipolar. Disord. , vol.10 , Issue.8 , pp. 957-968
    • Ghaemi, S.N.1
  • 69
    • 79551526477 scopus 로고    scopus 로고
    • Comparison of antidepressant responses in patients with bipolar vs. unipolar depression: A meta-analytic review
    • Vazquez G, Tondo L, Baldessarini RJ. Comparison of antidepressant responses in patients with bipolar vs. unipolar depression: a meta-analytic review. Pharmacopsychiatry 2011;44(1):21-6
    • (2011) Pharmacopsychiatry , vol.44 , Issue.1 , pp. 21-26
    • Vazquez, G.1    Tondo, L.2    Baldessarini, R.J.3
  • 70
    • 1442337923 scopus 로고    scopus 로고
    • Antidepressant treatment in bipolar versus unipolar depression
    • Ghaemi SN, Rosenquist KJ, Ko JY, et al. Antidepressant treatment in bipolar versus unipolar depression. Am J Psychiatry 2004;161(1):163-5
    • (2004) Am. J. Psychiatry , vol.161 , Issue.1 , pp. 163-165
    • Ghaemi, S.N.1    Rosenquist, K.J.2    Ko, J.Y.3
  • 71
    • 63249121697 scopus 로고    scopus 로고
    • Hypomania/mania induced by cessation of antidepressant drugs
    • Kora K, Kaplan P. Hypomania/mania induced by cessation of antidepressant drugs. Turk Psikiyatri Derg 2008;19(3):329-33
    • (2008) Turk. Psikiyatri. Derg. , vol.19 , Issue.3 , pp. 329-333
    • Kora, K.1    Kaplan, P.2
  • 72
    • 81855199265 scopus 로고    scopus 로고
    • Antidepressant-resistant depression and antidepressant-associated suicidal behaviour: The role of underlying bipolarity
    • Rihmer Z, Gonda X. Antidepressant-resistant depression and antidepressant-associated suicidal behaviour: the role of underlying bipolarity. Depress Res Treat 2011;2011:906462
    • (2011) Depress. Res. Treat. 2011 , pp. 906462
    • Rihmer, Z.1    Gonda, X.2
  • 73
    • 54149092541 scopus 로고    scopus 로고
    • Antidepressant-associated chronic irritable dysphoria ACID in STEP-BD patients
    • El-Mallakh RS, Ghaemi SN, Sagduyu K, et al. Antidepressant-associated chronic irritable dysphoria (ACID) in STEP-BD patients. J Affect Disord 2008;111(2-3):372-7
    • (2008) J. Affect. Disord. , vol.111 , Issue.2-3 , pp. 372-377
    • El-Mallakh, R.S.1    Ghaemi, S.N.2    Sagduyu, K.3
  • 74
    • 33746227776 scopus 로고    scopus 로고
    • Do antidepressants t hreaten depressives toward a clinically judicious formulation of the antidepressant-suicidality FDA advisory in light of declining national suicide statistics from many countries
    • Rihmer Z, Akiskal H. Do antidepressants t(h)reat(en) depressives? Toward a clinically judicious formulation of the antidepressant-suicidality FDA advisory in light of declining national suicide statistics from many countries. J Affect Disord 2006;94(1-3):3-13
    • (2006) J. Affect. Disord. , vol.94 , Issue.1-3 , pp. 3-13
    • Rihmer, Z.1    Akiskal, H.2
  • 75
    • 0008958563 scopus 로고    scopus 로고
    • The bipolar spectrum and the antidepressant view of the world
    • Ghaemi SN, Ko JY, Goodwin FK. The bipolar spectrum and the antidepressant view of the world. J Psychiatr Pract 2001;7(5):287-97
    • (2001) J. Psychiatr. Pract. , vol.7 , Issue.5 , pp. 287-297
    • Ghaemi, S.N.1    Ko, J.Y.2    Goodwin, F.K.3
  • 76
    • 0033761972 scopus 로고    scopus 로고
    • Development and validation of a screening instrument for bipolar spectrum disorder: The mood disorder questionnaire
    • Hirschfeld RM, Williams JB, Spitzer RL, et al. Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire. Am J Psychiatry 2000;157(11):1873-5
    • (2000) Am. J. Psychiatry , vol.157 , Issue.11 , pp. 1873-1875
    • Hirschfeld, R.M.1    Williams, J.B.2    Spitzer, R.L.3
  • 77
    • 33745143925 scopus 로고    scopus 로고
    • Bipolar or unipolar - The question for clinicians and researchers
    • Kiejna A, Rymaszewska J, Hadryś T, et al. Bipolar or unipolar? - the question for clinicians and researchers. J Affect Disord 2006;93(1-3):177-83
    • (2006) J. Affect. Disord. , vol.93 , Issue.1-3 , pp. 177-183
    • Kiejna, A.1    Rymaszewska, J.2    Hadryś, T.3
  • 78
    • 84862843599 scopus 로고    scopus 로고
    • Diagnostic criteria for bipolarity based on an international sample of 5 635 patients with DSM-IV major depressive episodes
    • Aug 5 Epub ahead of print]
    • Angst J, Gamma A, Bowden CL, et al. Diagnostic criteria for bipolarity based on an international sample of 5,635 patients with DSM-IV major depressive episodes. Eur Arch Psychiatry Clin Neurosci 2011 Aug 5. [Epub ahead of print]
    • (2011) Eur. Arch. Psychiatry Clin. Neurosci.
    • Angst, J.1    Gamma, A.2    Bowden, C.L.3
  • 79
    • 79961225126 scopus 로고    scopus 로고
    • Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: The BRIDGE study
    • Angst J, Azorin JM, Bowden CL, et al. Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: the BRIDGE study. Arch Gen Psychiatry 2011;68(8):791-8
    • (2011) Arch. Gen. Psychiatry , vol.68 , Issue.8 , pp. 791-798
    • Angst, J.1    Azorin, J.M.2    Bowden, C.L.3
  • 80
    • 1342311506 scopus 로고    scopus 로고
    • A review of antidepressant-induced hypomania in major depression: Suggestions for DSM-V
    • Chun BJ, Dunner DL. A review of antidepressant-induced hypomania in major depression: suggestions for DSM-V. Bipolar Disord 2004;6(1):32-42
    • (2004) Bipolar. Disord. , vol.6 , Issue.1 , pp. 32-42
    • Chun, B.J.1    Dunner, D.L.2
  • 81
    • 0023215677 scopus 로고
    • Criteria for the soft bipolar spectrum: Treatment implications
    • Akiskal HS, Mallya G. Criteria for the 'soft' bipolar spectrum: treatment implications. Psychopharmacol Bull 1987;23(1):68-73
    • (1987) Psychopharmacol. Bull. , vol.23 , Issue.1 , pp. 68-73
    • Akiskal, H.S.1    Mallya, G.2
  • 82
    • 26944477464 scopus 로고    scopus 로고
    • Is your depressed patient bipolar
    • Kaye NS. Is your depressed patient bipolar? J Am Board Fam Pract 2005;18(4):271-81
    • (2005) J. Am. Board. Fam. Pract. , vol.18 , Issue.4 , pp. 271-281
    • Kaye, N.S.1
  • 83
    • 0031941615 scopus 로고    scopus 로고
    • The high prevalence of soft bipolar II features in atypical depression
    • Perugi G, Akiskal HS, Lattanzi L, et al. The high prevalence of 'soft' bipolar (II) features in atypical depression. Compr Psychiatry 1998;39(2):63-71
    • (1998) Compr. Psychiatry , vol.39 , Issue.2 , pp. 63-71
    • Perugi, G.1    Akiskal, H.S.2    Lattanzi, L.3
  • 84
    • 67649231052 scopus 로고    scopus 로고
    • What predicts attrition in second step medication treatments for depression: A STAR.*D report
    • Warden D, Rush AJ, Wisniewski SR, et al. What predicts attrition in second step medication treatments for depression?: a STAR. z.ast;D Report. Int J Neuropsychopharmacol 2009;12(4):459-73
    • (2009) Int. J. Neuropsychopharmacol. , vol.12 , Issue.4 , pp. 459-473
    • Warden, D.1    Rush, A.J.2    Wisniewski, S.R.3
  • 85
    • 71549130441 scopus 로고    scopus 로고
    • HTR2A gene variation is involved in antidepressant treatment response
    • Lucae S, et al. HTR2A gene variation is involved in antidepressant treatment response. Eur Neuropsychopharmacol 2010;20(1):65-8
    • (2010) Eur. Neuropsychopharmacol. , vol.20 , Issue.1 , pp. 65-68
    • Lucae, S.1
  • 86
    • 79952396535 scopus 로고    scopus 로고
    • Are atypical depression borderline personality disorder and bipolar II disorder overlapping manifestations of a common cyclothymic diathesis
    • Perugi G, Fornaro M, Akiskal HS, et al. Are atypical depression, borderline personality disorder and bipolar II disorder overlapping manifestations of a common cyclothymic diathesis? World Psychiatry 2011;10(1):45-51
    • (2011) World Psychiatry , vol.10 , Issue.1 , pp. 45-51
    • Perugi, G.1    Fornaro, M.2    Akiskal, H.S.3
  • 87
    • 0032953755 scopus 로고    scopus 로고
    • Is bipolar disorder still underdiagnosed are antidepressants overutilized
    • Ghaemi SN, et al. Is bipolar disorder still underdiagnosed? Are antidepressants overutilized? J Affect Disord 1999;52(1-3):135-44
    • (1999) J. Affect. Disord. , vol.52 , Issue.1-3 , pp. 135-144
    • Ghaemi, S.N.1
  • 88
    • 0038730792 scopus 로고    scopus 로고
    • How accurate are patients in reporting their antidepressant treatment history
    • Posternak MA, Zimmerman M. How accurate are patients in reporting their antidepressant treatment history? J Affect Disord 2003;75(2):115-24
    • (2003) J. Affect. Disord. , vol.75 , Issue.2 , pp. 115-124
    • Posternak, M.A.1    Zimmerman, M.2
  • 89
    • 77957893000 scopus 로고    scopus 로고
    • Can single genes matter in a polygenic world
    • Perlis RH. Can single genes matter in a polygenic world? Biol Psychiatry 2010;68(9):783-4
    • (2010) Biol. Psychiatry , vol.68 , Issue.9 , pp. 783-784
    • Perlis, R.H.1
  • 90
    • 0033623241 scopus 로고    scopus 로고
    • The implications of genetics studies of major mood disorders for clinical practice
    • Duffy A, et al. The implications of genetics studies of major mood disorders for clinical practice. J Clin Psychiatry 2000;61(9):630-7
    • (2000) J. Clin. Psychiatry , vol.61 , Issue.9 , pp. 630-637
    • Duffy, A.1
  • 91
    • 68449086236 scopus 로고    scopus 로고
    • International schizophrenia consortium common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • Purcell SM, Wray NR, Stone JL, et al. International Schizophrenia Consortium. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009;460(7256):748-52
    • (2009) Nature , vol.460 , Issue.7256 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3
  • 92
    • 79952718241 scopus 로고    scopus 로고
    • Betting on biomarkers
    • Perlis RH. Betting on biomarkers. Am J Psychiatry 2011;168(3):234-6
    • (2011) Am. J. Psychiatry , vol.168 , Issue.3 , pp. 234-236
    • Perlis, R.H.1
  • 94
    • 77953962523 scopus 로고    scopus 로고
    • Meta-analysis of BDNF Val66Met polymorphism association with treatment response in patients with major depressive disorder
    • Zou YF, Ye DQ, Feng XL, et al. Meta-analysis of BDNF Val66Met polymorphism association with treatment response in patients with major depressive disorder. Eur Neuropsychopharmacol 2010;20(8):535-44
    • (2010) Eur. Neuropsychopharmacol. , vol.20 , Issue.8 , pp. 535-544
    • Zou, Y.F.1    Ye, D.Q.2    Feng, X.L.3
  • 95
    • 77950297308 scopus 로고    scopus 로고
    • Neuropeptide Y NPY gene: Impact on emotional processing and treatment response in anxious depression
    • Domschke K, Dannlowski U, Hohoff C, et al. Neuropeptide Y (NPY) gene: impact on emotional processing and treatment response in anxious depression. Eur Neuropsychopharmacol 2010;20(5):301-9
    • (2010) Eur. Neuropsychopharmacol. , vol.20 , Issue.5 , pp. 301-309
    • Domschke, K.1    Dannlowski, U.2    Hohoff, C.3
  • 96
    • 80052002492 scopus 로고    scopus 로고
    • Variation in GNB3 predicts response and adverse reactions to antidepressants
    • Keers R, Bonvicini C, Scassellati C, et al. Variation in GNB3 predicts response and adverse reactions to antidepressants. J Psychopharmacol 2011;25(7):867-74
    • (2011) J. Psychopharmacol. , vol.25 , Issue.7 , pp. 867-874
    • Keers, R.1    Bonvicini, C.2    Scassellati, C.3
  • 97
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of dsm-iv disorders in the national comorbidity survey replication
    • Kessler RC, Berglund P, Demler O, et al. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005;62(6):593-602
    • (2005) Arch. Gen. Psychiatry , vol.62 , Issue.6 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3
  • 98
    • 77952571701 scopus 로고    scopus 로고
    • The perfect storm: CNS drug development in trouble
    • Nierenberg AA. The perfect storm: CNS drug development in trouble. CNS Spectr 2010;15(5):282-3
    • (2010) CNS Spectr. , vol.15 , Issue.5 , pp. 282-283
    • Nierenberg, A.A.1
  • 99
    • 2342548183 scopus 로고    scopus 로고
    • Bipolar depression: The real challenge
    • Hirschfeld RM. Bipolar depression: the real challenge. Eur Neuropsychopharmacol 2004;14(Suppl 2):S83-8
    • (2004) Eur. Neuropsychopharmacol. , vol.14 , Issue.2
    • Hirschfeld, R.M.1
  • 100
    • 0036234164 scopus 로고    scopus 로고
    • Cades disease and beyond: Misdiagnosis antidepressant use and a proposed definition for bipolar spectrum disorder
    • Ghaemi SN, Ko JY, Goodwin FK. 'Cade's disease' and beyond: misdiagnosis, antidepressant use, and a proposed definition for bipolar spectrum disorder. Can J Psychiatry 2002;47(2):125-34
    • (2002) Can. J. Psychiatry , vol.47 , Issue.2 , pp. 125-134
    • Ghaemi, S.N.1    Ko, J.Y.2    Goodwin, F.K.3
  • 101
    • 0032171097 scopus 로고    scopus 로고
    • The emerging epidemiology of hypomania and bipolar II disorder
    • Angst J. The emerging epidemiology of hypomania and bipolar II disorder. J Affect Disord 1998;50(2-3):143-51
    • (1998) J. Affect. Disord. , vol.50 , Issue.2-3 , pp. 143-151
    • Angst, J.1
  • 103
    • 0036270011 scopus 로고    scopus 로고
    • The long-term natural history of the weekly symptomatic status of bipolar I disorder
    • Judd LL, Akiskal HS, Schettler PJ, et al. The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry 2002;59(6):530-7
    • (2002) Arch. Gen. Psychiatry , vol.59 , Issue.6 , pp. 530-537
    • Judd, L.L.1    Akiskal, H.S.2    Schettler, P.J.3
  • 104
    • 0036182222 scopus 로고    scopus 로고
    • Demographic and clinical characteristics of individuals in a bipolar disorder case registry
    • Kupfer DJ, Frank E, Grochocinski VJ, et al. Demographic and clinical characteristics of individuals in a bipolar disorder case registry. J Clin Psychiatry 2002;63(2):120-5
    • (2002) J. Clin. Psychiatry , vol.63 , Issue.2 , pp. 120-125
    • Kupfer, D.J.1    Frank, E.2    Grochocinski, V.J.3
  • 105
    • 0035208089 scopus 로고    scopus 로고
    • Integration of suicide prevention into outpatient management of bipolar disorder
    • Sachs GS, Yan LJ, Swann AC, Allen MH. Integration of suicide prevention into outpatient management of bipolar disorder. J Clin Psychiatry 2001;62(Suppl 25):3-11
    • (2001) J. Clin. Psychiatry , vol.62 , Issue.25 , pp. 3-11
    • Sachs, G.S.1    Yan, L.J.2    Swann, A.C.3    Allen, M.H.4
  • 106
    • 77956008522 scopus 로고    scopus 로고
    • Suicidality and risk of suicide - Definition drug safety concerns and a necessary target for drug development: A consensus statement
    • Meyer RE, Salzman C, Youngstrom EA, et al. Suicidality and risk of suicide-definition, drug safety concerns, and a necessary target for drug development: a consensus statement. J Clin Psychiatry 2010;71(8):e1-e21
    • (2010) J. Clin. Psychiatry , vol.71 , Issue.8
    • Meyer, R.E.1    Salzman, C.2    Youngstrom, E.A.3
  • 107
    • 41549083891 scopus 로고    scopus 로고
    • Toward a Hippocratic psychopharmacology
    • Ghaemi SN. Toward a Hippocratic psychopharmacology. Can J Psychiatry 2008;53(3):189-96
    • (2008) Can. J. Psychiatry , vol.53 , Issue.3 , pp. 189-196
    • Ghaemi, S.N.1
  • 108
    • 0035719884 scopus 로고    scopus 로고
    • Bipolarity from ancient to modern times: Conception birth and rebirth
    • Angst J, Marneros A. Bipolarity from ancient to modern times: conception, birth and rebirth. J Affect Disord 2001;67(1-3):3-19
    • (2001) J. Affect. Disord. , vol.67 , Issue.1-3 , pp. 3-19
    • Angst, J.1    Marneros, A.2
  • 110
    • 0034950547 scopus 로고    scopus 로고
    • Bipolar spectrum disorder: Improving its recognition and diagnosis
    • Hirschfeld RM. Bipolar spectrum disorder: improving its recognition and diagnosis. J Clin Psychiatry 2001;62(Suppl 14):5-9
    • (2001) J. Clin. Psychiatry , vol.62 , Issue.14 , pp. 5-9
    • Hirschfeld, R.M.1
  • 111
    • 67349229539 scopus 로고    scopus 로고
    • What happens to patients with treatment-resistant depression a systematic review of medium to long term outcome studies
    • Fekadu A, et al. What happens to patients with treatment-resistant depression? A systematic review of medium to long term outcome studies. J Affect Disord 2009;116(1-2):4-11
    • (2009) J. Affect. Disord. , vol.116 , Issue.1-2 , pp. 4-11
    • Fekadu, A.1
  • 112
    • 0038824219 scopus 로고    scopus 로고
    • Is treatment-resistant depression a unique subtype of depression
    • Fagiolini A, Kupfer DJ. Is treatment-resistant depression a unique subtype of depression? Biol Psychiatry 2003;53(8):640-8
    • (2003) Biol. Psychiatry , vol.53 , Issue.8 , pp. 640-648
    • Fagiolini, A.1    Kupfer, D.J.2
  • 113
    • 34248381347 scopus 로고    scopus 로고
    • Definition assessment and staging of treatment-resistant refractory major depression: A review of current concepts and methods
    • Berlim MT, Turecki G. Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods. Can J Psychiatry 2007;52(1):46-54
    • (2007) Can. J. Psychiatry , vol.52 , Issue.1 , pp. 46-54
    • Berlim, M.T.1    Turecki, G.2
  • 114
    • 0004385812 scopus 로고    scopus 로고
    • Are all antidepressants alike
    • Schultz P. Are all antidepressants alike? Dialogues Clin Neurosci 1999;1(1):4-11
    • (1999) Dialogues. Clin. Neurosci. , vol.1 , Issue.1 , pp. 4-11
    • Schultz, P.1
  • 116
    • 0034237032 scopus 로고    scopus 로고
    • Nosologomania: A disorder of psychiatry
    • van Praag HM. Nosologomania: a disorder of psychiatry. World J Biol Psychiatry 2000;1(3):151-8
    • (2000) World J. Biol. Psychiatry , vol.1 , Issue.3 , pp. 151-158
    • Van Praag, H.M.1
  • 117
    • 75749155873 scopus 로고    scopus 로고
    • The development of the feighner criteria: A historical perspective
    • Kendler KS, Munoz RA, Murphy G. The development of the Feighner criteria: a historical perspective. Am J Psychiatry 2010;167(2):134-42
    • (2010) Am. J. Psychiatry , vol.167 , Issue.2 , pp. 134-142
    • Kendler, K.S.1    Munoz, R.A.2    Murphy, G.3
  • 118
    • 0037222023 scopus 로고    scopus 로고
    • Validating hard and soft phenotypes within the bipolar spectrum: Continuity or discontinuity
    • Akiskal HS. Validating 'hard' and 'soft' phenotypes within the bipolar spectrum: continuity or discontinuity? J Affect Disord 2003;73(1-2):1-5
    • (2003) J. Affect. Disord. , vol.73 , Issue.1-2 , pp. 1-5
    • Akiskal, H.S.1
  • 119
    • 33744797073 scopus 로고    scopus 로고
    • Toward a unitary perspective on the bipolar spectrum and substance abuse: Opiate addiction as a paradigm
    • Maremmani I, Perugi G, Pacini M, Akiskal HS. Toward a unitary perspective on the bipolar spectrum and substance abuse: opiate addiction as a paradigm. J Affect Disord 2006;93(1-3):1-12
    • (2006) J. Affect. Disord. , vol.93 , Issue.1-3 , pp. 1-12
    • Maremmani, I.1    Perugi, G.2    Pacini, M.3    Akiskal, H.S.4
  • 120
    • 78649606509 scopus 로고    scopus 로고
    • A genome-wide association study of bipolar disorder and comorbid migraine
    • Oedegaard KJ, Greenwood TA, Johansson S, et al. A genome-wide association study of bipolar disorder and comorbid migraine. Genes Brain Behav 2010;9(7):673-80
    • (2010) Genes. Brain. Behav. , vol.9 , Issue.7 , pp. 673-680
    • Oedegaard, K.J.1    Greenwood, T.A.2    Johansson, S.3
  • 121
    • 20344391680 scopus 로고    scopus 로고
    • Comorbidity of bipolar and eating disorders: Distinct or related disorders with shared dysregulations
    • McElroy SL, Kotwal R, Keck PE Jr, Akiskal HS. Comorbidity of bipolar and eating disorders: distinct or related disorders with shared dysregulations? J Affect Disord 2005;86(2-3):107-27
    • (2005) J. Affect. Disord. , vol.86 , Issue.2-3 , pp. 107-127
    • McElroy, S.L.1    Kotwal, R.2    Keck Jr., P.E.3    Akiskal, H.S.4
  • 122
    • 77956179033 scopus 로고    scopus 로고
    • Design syn thesis and biological evaluation of new monoamine reuptake inhibitors with potential therapeutic utility in depression and pain
    • Lucas MC, Weikert RJ, Carter DS, et al. Design, synthesis, and biological evaluation of new monoamine reuptake inhibitors with potential therapeutic utility in depression and pain. Bioorg Med Chem Lett 2010;20(18):5559-66
    • (2010) Bioorg. Med. Chem. Lett. , vol.20 , Issue.18 , pp. 5559-5566
    • Lucas, M.C.1    Weikert, R.J.2    Carter, D.S.3
  • 123
    • 66149110404 scopus 로고    scopus 로고
    • Triple reuptake inhibitors: The next generation of antidepressants
    • Marks DM, Pae CU, Patkar AA. Triple reuptake inhibitors: the next generation of antidepressants. Curr Neuropharmacol 2008;6(4):338-43
    • (2008) Curr. Neuropharmacol. , vol.6 , Issue.4 , pp. 338-343
    • Marks, D.M.1    Pae, C.U.2    Patkar, A.A.3
  • 124
    • 0003558989 scopus 로고    scopus 로고
    • Stahl S. editor 3rd edition. Neuroscientific Basis and Practical Applications; Cambridge: San Diego:
    • Stahl S. editor. Stahl's essential psychopharmacology. 3rd edition. Neuroscientific Basis and Practical Applications; Cambridge: San Diego: 2008
    • (2008) Stahls Essential Psychopharmacology
  • 125
    • 79952005934 scopus 로고    scopus 로고
    • Mechanisms underlying ketamine-induced synaptic depression in rat hippocampus-medialprefrontal cortex pathway
    • Kamiyama H, et al. Mechanisms underlying ketamine-induced synaptic depression in rat hippocampus-medialprefrontal cortex pathway. Neuroscience 2011;177:159-69
    • (2011) Neuroscience , vol.177 , pp. 159-169
    • Kamiyama, H.1
  • 126
    • 77954958226 scopus 로고    scopus 로고
    • Mifepristone decreases depression-like behavior and modulates neuroendocrine and central hypothalamic-pituitary-adrenocortical axis responsiveness to stress
    • Wulsin AC, Herman JP, Solomon MB. Mifepristone decreases depression-like behavior and modulates neuroendocrine and central hypothalamic-pituitary- adrenocortical axis responsiveness to stress. Psychoneuroendocrinology 2010;35(7):1100-12
    • (2010) Psychoneuroendocrinology , vol.35 , Issue.7 , pp. 1100-1112
    • Wulsin, A.C.1    Herman, J.P.2    Solomon, M.B.3
  • 127
    • 59449093286 scopus 로고    scopus 로고
    • SSR149415 a non-peptide vasopressin V1b receptor antagonist has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model
    • Breuer ME, et al. SSR149415, a non-peptide vasopressin V1b receptor antagonist, has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model. Naunyn Schmiedebergs Arch Pharmacol 2009;379(1):101-6
    • (2009) Naunyn. Schmiedebergs. Arch. Pharmacol. , vol.379 , Issue.1 , pp. 101-106
    • Breuer, M.E.1
  • 128
    • 0022922439 scopus 로고
    • CPP a new potent and selective NMDA antagonist depression of central neuron responses affinity for 3HD-AP5 binding sites on brain membranes and anticonvulsant activity
    • Davies J, et al. CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity. Brain Res 1986;382(1):169-73
    • (1986) Brain Res. , vol.382 , Issue.1 , pp. 169-173
    • Davies, J.1
  • 129
    • 21644461450 scopus 로고    scopus 로고
    • Regionally selective and dose-dependent effects of the ampakines org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography
    • Jordan GR, et al. Regionally selective and dose-dependent effects of the ampakines Org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography.Neuropharmacology 2005;49(2):254-64
    • (2005) Neuropharmacology , vol.49 , Issue.2 , pp. 254-264
    • Jordan, G.R.1
  • 130
    • 36048976944 scopus 로고    scopus 로고
    • Role of GABA in anxiety and depression
    • Kalueff AV, Nutt DJ. Role of GABA in anxiety and depression. Depress Anxiety 2007;24(7):495-517
    • (2007) Depress. Anxiety. , vol.24 , Issue.7 , pp. 495-517
    • Kalueff, A.V.1    Nutt, D.J.2
  • 131
    • 0022612248 scopus 로고
    • GABA and circadian timekeeping: Implications for manic-depression and sleep disorders
    • Borsook D, et al. GABA and circadian timekeeping: implications for manic-depression and sleep disorders. Med Hypotheses 1986;19(2):185-98
    • (1986) Med. Hypotheses. , vol.19 , Issue.2 , pp. 185-198
    • Borsook, D.1
  • 132
    • 0036755157 scopus 로고    scopus 로고
    • Depression antidepressant therapies and erectile dysfunction: Clinical trials of sildenafil citrate viagra in treated and untreated patients with depression
    • Nurnberg HG, Seidman SN, Gelenberg AJ, et al. Depression, antidepressant therapies, and erectile dysfunction: clinical trials of sildenafil citrate (Viagra) in treated and untreated patients with depression. Urology 2002;60(2 Suppl 2):58-66
    • (2002) Urology , vol.60 , Issue.2 , pp. 58-66
    • Nurnberg, H.G.1    Seidman, S.N.2    Gelenberg, A.J.3
  • 133
    • 41949132109 scopus 로고    scopus 로고
    • Confirmation of antidepressant potential of the selective beta3 adrenoceptor agonist amibegron in an animal model of depression
    • Overstreet DH, Stemmelin J, Griebel G. Confirmation of antidepressant potential of the selective beta3 adrenoceptor agonist amibegron in an animal model of depression. Pharmacol Biochem Behav 2008;89(4):623-6
    • (2008) Pharmacol. Biochem. Behav. , vol.89 , Issue.4 , pp. 623-626
    • Overstreet, D.H.1    Stemmelin, J.2    Griebel, G.3
  • 134
    • 57349115973 scopus 로고    scopus 로고
    • The sigma enigma: Can sigma receptors provide a novel target for disorders of mood and cognition
    • Stahl SM. The sigma enigma: can sigma receptors provide a novel target for disorders of mood and cognition? J Clin Psychiatry 2008;69(11):1673-4
    • (2008) J. Clin. Psychiatry , vol.69 , Issue.11 , pp. 1673-1674
    • Stahl, S.M.1
  • 135
    • 34247605930 scopus 로고    scopus 로고
    • Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality
    • Naidu PS, Varvel SA, Ahn K, et al. Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. Psychopharmacology (Berl) 2007;192(1):61-70
    • (2007) Psychopharmacology Berl. , vol.192 , Issue.1 , pp. 61-70
    • Naidu, P.S.1    Varvel, S.A.2    Ahn, K.3
  • 136
    • 78649505983 scopus 로고    scopus 로고
    • Maintenance therapy of celecoxib for major depression with mimicking neuropsychological dysfunction
    • 647
    • Chen CY, Tzeng NS, Chen YC. Maintenance therapy of celecoxib for major depression with mimicking neuropsychological dysfunction. Gen Hosp Psychiatry 2010;32(6):647; e7-9
    • (2010) Gen. Hosp. Psychiatry , vol.32 , Issue.6
    • Chen, C.Y.1    Tzeng, N.S.2    Chen, Y.C.3
  • 137
    • 39749174334 scopus 로고    scopus 로고
    • Antidepressant monotherapy in pre-bipolar depression; predictive value and inherent risk
    • O'Donovan C, Garnham JS, Hajek T, Alda M. Antidepressant monotherapy in pre-bipolar depression; predictive value and inherent risk. J Affect Disord 2008;107(1-3):293-8
    • (2008) J. Affect. Disord. , vol.107 , Issue.1-3 , pp. 293-298
    • O'Donovan, C.1    Garnham, J.S.2    Hajek, T.3    Alda, M.4
  • 138
    • 80052493697 scopus 로고    scopus 로고
    • A predictive model for diagnosing bipolar disorder based on the clinical characteristics of major depressive episodes in Chinese population
    • Gan Z, Diao F, Wei Q, et al. A predictive model for diagnosing bipolar disorder based on the clinical characteristics of major depressive episodes in Chinese population. J Affect Disord 2011
    • (2011) J. Affect. Disord.
    • Gan, Z.1    Diao, F.2    Wei, Q.3
  • 139
    • 50849103187 scopus 로고    scopus 로고
    • Development and validation of an international risk prediction algorithm for episodes of major depression in general practice attendees: The predictd study
    • King M, et al. Development and validation of an international risk prediction algorithm for episodes of major depression in general practice attendees: the PredictD study. Arch Gen Psychiatry 2008;65(12):1368-76
    • (2008) Arch. Gen. Psychiatry , vol.65 , Issue.12 , pp. 1368-1376
    • King, M.1
  • 140
    • 33344464148 scopus 로고    scopus 로고
    • A stepwise drug treatment algorithm to obtain complete remission in depression: A geneva study
    • Bondolfi G, Aubry JM, Golaz J, et al. A stepwise drug treatment algorithm to obtain complete remission in depression: a Geneva study. Swiss Med Wkly 2006;136(5-6):78-85
    • (2006) Swiss. Med. Wkly. , vol.136 , Issue.5-6 , pp. 78-85
    • Bondolfi, G.1    Aubry, J.M.2    Golaz, J.3
  • 141
    • 80052472694 scopus 로고    scopus 로고
    • Algorithm-guided treatment of depression reduces treatment costs - Results from the randomized controlled german algorithm project GAPII
    • Ricken R, Wiethoff K, Reinhold T, et al. Algorithm-guided treatment of depression reduces treatment costs - Results from the randomized controlled German Algorithm Project (GAPII).J Affect Disord 2011
    • (2011) J. Affect. Disord.
    • Ricken, R.1    Wiethoff, K.2    Reinhold, T.3
  • 142
    • 68449098784 scopus 로고    scopus 로고
    • Efficacy of an algorithm-guided treatment compared with treatment as usual: A randomized controlled study of inpatients with depression
    • Bauer M, et al. Efficacy of an algorithm-guided treatment compared with treatment as usual: a randomized, controlled study of inpatients wih depression. J Clin Psychopharmacol 2009;29(4):327-33
    • (2009) J. Clin. Psychopharmacol. , vol.29 , Issue.4 , pp. 327-333
    • Bauer, M.1
  • 143
    • 3042702585 scopus 로고    scopus 로고
    • Clinical results for patients with major depressive disorder in the texas medication algorithm project
    • Trivedi MH, et al. Clinical results for patients with major depressive disorder in the Texas Medication Algorithm Project. Arch Gen Psychiatry 2004;61(7):669-80
    • (2004) Arch. Gen. Psychiatry , vol.61 , Issue.7 , pp. 669-680
    • Trivedi, M.H.1
  • 144
    • 68349133563 scopus 로고    scopus 로고
    • Extended-release trazodone in major depressive disorder: A randomized double-lind, placebo-controlled study
    • Sheehan DV, Croft HA, Gossen ER, et al. Extended-release trazodone in major depressive disorder: a randomized, double-blind, placebo-controlled study. Psychiatry (Edgmont) 2009;6(5):20-33
    • (2009) Psychiatry Edgmont. , vol.6 , Issue.5 , pp. 20-33
    • Sheehan, D.V.1    Croft, H.A.2    Gossen, E.R.3
  • 145
    • 67649624781 scopus 로고    scopus 로고
    • Desvenlafaxine: A new antidepressant or just another one
    • Pae CU. Desvenlafaxine: a new antidepressant or just another one? Expert Opin Pharmacother 2009;10(5):875-87
    • (2009) Expert. Opin. Pharmacother. , vol.10 , Issue.5 , pp. 875-887
    • Pae, C.U.1
  • 146
    • 79952748673 scopus 로고    scopus 로고
    • Lu-AA21004 a multimodal serotonergic agent for the potential treatment of depression and anxiety
    • Adell A. Lu-AA21004, a multimodal serotonergic agent, for the potential treatment of depression and anxiety. IDrugs 2010;13(12):900-10
    • (2010) IDrugs , vol.13 , Issue.12 , pp. 900-910
    • Adell, A.1
  • 147
    • 79952522397 scopus 로고    scopus 로고
    • Vilazodone: Another novel atypical antidepressant drug
    • Howland RH. Vilazodone: another novel atypical antidepressant drug. J Psychosoc Nurs Ment Health Serv 2011;49(3):19-22
    • (2011) J. Psychosoc. Nurs. Ment. Health Serv. , vol.49 , Issue.3 , pp. 19-22
    • Howland, R.H.1
  • 148
    • 0037364032 scopus 로고    scopus 로고
    • Gepirone extended-release: New evidence for efficacy in the treatment of major depressive disorder
    • Feiger AD, Heiser JF, Shrivastava RK, et al. Gepirone extended-release: new evidence for efficacy in the treatment of major depressive disorder. J Clin Psychiatry 2003;64(3):243-9
    • (2003) J. Clin. Psychiatry , vol.64 , Issue.3 , pp. 243-249
    • Feiger, A.D.1    Heiser, J.F.2    Shrivastava, R.K.3
  • 149
    • 33947395654 scopus 로고    scopus 로고
    • Drug evaluation: PRX-00023 a selective 5-HT1A receptor agonist for depression
    • de Paulis T. Drug evaluation: PRX-00023, a selective 5-HT1A receptor agonist for depression. Curr Opin Investig Drugs 2007;8(1):78-86
    • (2007) Curr. Opin. Investig. Drugs. , vol.8 , Issue.1 , pp. 78-86
    • De Paulis, T.1
  • 150
    • 33845734220 scopus 로고    scopus 로고
    • Effects of OPC-14523 a combined sigma and 5-HT1a ligand on pre- and post-synaptic 5-HT1a receptors
    • Epub 2006 Mar 13
    • Bermack JE, Debonnel G. Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors. J Psychopharmacol 2007;21(1):85-92. Epub 2006 Mar 13
    • (2007) J. Psychopharmacol. , vol.21 , Issue.1 , pp. 85-92
    • Bermack, J.E.1    Debonnel, G.2
  • 151
    • 33644850947 scopus 로고    scopus 로고
    • Basic mechanisms of augmentation of antidepressant effects with thyroid hormone
    • Lifschytz T, Segman R, Shalom G, et al. Basic mechanisms of augmentation of antidepressant effects with thyroid hormone. Curr Drug Targets 2006;7(2):203-10
    • (2006) Curr. Drug. Targets. , vol.7 , Issue.2 , pp. 203-210
    • Lifschytz, T.1    Segman, R.2    Shalom, G.3
  • 152
    • 33645098370 scopus 로고    scopus 로고
    • Bupropion-SR sertraline or venlafaxine-XR after failure of SSRIs for depression
    • Rush AJ, Trivedi MH, Wisniewski SR, et al. Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression. N Engl J Med 2006;354(12):1231-42
    • (2006) N. Engl. J. Med. , vol.354 , Issue.12 , pp. 1231-1242
    • Rush, A.J.1    Trivedi, M.H.2    Wisniewski, S.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.