Reductive metabolism increases the proinflammatory activity of aldehyde phospholipids

Journal of Lipid Research

Volumn 52, Issue 12, 2011, Pages 2209-2225

  Vladykovskaya, Elena ^a   Ozhegov, Evgeny ^a   Hoetker, J David ^a   Xie, Zhengzhi ^a   Ahmed, Yonis ^a   Suttles, Jill ^a   Srivastava, Sanjay ^a   Bhatnagar, Aruni ^a   Barski, Oleg A ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Aldose reductase; Cytokines; Gene expression; Macrophages; Phospholipase A 2; POVPC

Indexed keywords

1 PALMITOYL 2 (5 HYDROXYVALEROYL) SN GLYCERO 3 PHOSPHOCHOLINE; 1 PALMITOYL 2 (5' OXOVALEROYL) SN GLYCERO 3 PHOSPHOCHOLINE; 4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; ALDEHYDE REDUCTASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LYSOPHOSPHATIDYLCHOLINE; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHOLIPASE A2; PHOSPHOLIPID; TOLRESTAT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE; GENE EXPRESSION; GENE INDUCTION; GM CSF GENE; HUMAN; HUMAN CELL; IL 1BETA GENE; IL 6 GENE; IL 8 GENE; INFLAMMATION; LIPID HYDROLYSIS; LIPID STORAGE; MACROPHAGE; MCP 1 GENE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; TNF ALPHA GENE; UPREGULATION;

ALDEHYDE REDUCTASE; ANIMALS; CELL LINE; CYTOKINES; HUMANS; INFLAMMATION; MACROPHAGES; MICE; OXIDATION-REDUCTION; PHOSPHOLIPID ETHERS; UP-REGULATION;

EID: 81855161284     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M013854     Document Type: Article

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