Novel mitochondria-targeted antioxidant peptide ameliorates burn-induced apoptosis and endoplasmic reticulum stress in the skeletal muscle of mice

Shock

Volumn 36, Issue 6, 2011, Pages 580-585

  Lee, Hyung Yul ^a   Kaneki, Masao ^a   Andreas, Jonathan ^a   Tompkins, Ronald G ^a   Martyn, J A Jeevendra ^a  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

burn injury; insulin resistance; reactive oxygen species; SS 31 peptide

Indexed keywords

BINDING IMMUNOGLOBULIN PROTEIN; BINDING PROTEIN; CASPASE 3; PEPTIDE; PEPTIDE SS 31; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN DISULFIDE ISOMERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY SURFACE; BURN; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; INSULIN SENSITIVITY; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RECTUS ABDOMINIS MUSCLE; SKELETAL MUSCLE;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BURNS; ENDOPLASMIC RETICULUM STRESS; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MUSCLE, SKELETAL; OLIGOPEPTIDES; REACTIVE OXYGEN SPECIES;

EID: 81755184121     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3182366872     Document Type: Article

References (35)

1. Cree MG, Wolfe RR: Postburn trauma insulin resistance and fat metabolism. Am J Physiol Endocrinol Metab 294(1):E1-E9, 2008.
2. Demling RH, Seigne P: Metabolic management of patients with severe burns. World J Surg 24(6):673-680, 2000. (Pubitemid 30331842)
3. Pereira C, Murphy K, Jeschke M, Herndon DN: Post burn muscle wasting and the effects of treatments. Int J Biochem Cell Biol 37(10):1948-1961, 2005. (Pubitemid 41206813)
4. Lowell BB, Shulman GI: Mitochondrial dysfunction and type 2 diabetes. Science 307(5708):384-387, 2005. (Pubitemid 40139974)
5. Yokota T, Kinugawa S, Hirabayashi K, Matsushima S, Inoue N, Ohta Y, Hamaguchi S, Sobirin MA, Ono T, Suga T, et al.: Oxidative stress in skeletal muscle impairs mitochondrial respiration and limits exercise capacity in type 2 diabetic mice. Am J Physiol Heart Circ Physiol 297(3):H1069-H1077, 2009.
6. Hotamisligil GS: Inflammation and metabolic disorders. Nature 444(7121): 860-867, 2006. (Pubitemid 46024993)
7. Hotamisligil GS: Inflammation and endoplasmic reticulum stress in obesity and diabetes. Int J Obes (Lond) 32(Suppl 7):S52-S54, 2008.
8. Padfield KE, Astrakas LG, Zhang Q, Gopalan S, Dai G, Mindrinos MN, Tompkins RG, Rahme LG, Tzika AA: Burn injury causes mitochondrial dysfunction in skeletal muscle. Proc Natl Acad Sci USA 102(15):5368-5373, 2005. (Pubitemid 40530264)
9. Sugita H, Kaneki M, Sugita M, Yasukawa T, Yasuhara S, Martyn JA: Burn injury impairs insulin-stimulated Akt/PKB activation in skeletal muscle. Am J Physiol Endocrinol Metab 288(3):E585-E591, 2005. (Pubitemid 40250554)
10. Yasuhara S, Perez ME, Kanakubo E, Yasuhara Y, Shin YS, Kaneki M, Fujita T, Martyn JA: Skeletal muscle apoptosis after burns is associated with activation of proapoptotic signals. Am J Physiol Endocrinol Metab 279(5):E1114-E1121, 2000.
11. Astrakas LG, Goljer I, Yasuhara S, Padfield KE, Zhang Q, Gopalan S, Mindrinos MN, Dai G, Yu YM, Martyn JA, et al.: Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis. FASEB J 19(11):1431-1440, 2005. (Pubitemid 41279001)
12. Yasuhara S, Kaneki M, Sugita H, Sugita M, Asai A, Sahani N, Chon JY, Tompkins RG, Martyn JA: Adipocyte apoptosis after burn injury is associated with altered fat metabolism. J Burn Care Res 27(3):367-376, 2006. (Pubitemid 43970305)
13. Jeschke MG, Gauglitz GG, Song J, Kulp GA, Finnerty CC, Cox RA, Barral JM, Herndon DN, Boehning D: Calcium and ER stress mediate hepatic apoptosis after burn injury. J Cell Mol Med 13(8B):1857-1865, 2009.
14. Parihar A, Parihar MS, Milner S, Bhat S: Oxidative stress and anti-oxidative mobilization in burn injury. Burns 34(1):6-17, 2008.
15. Song J, Finnerty CC, Herndon DN, Boehning D, Jeschke MG: Severe burninduced endoplasmic reticulum stress and hepatic damage in mice. Mol Med 15(9-10):316-320, 2009.
16. Shimizu Y, Hendershot LM: Oxidative folding: cellular strategies for dealing with the resultant equimolar production of reactive oxygen species. Antioxid Redox Signal 11(9):2317-2331, 2009.
17. Shoelson SE, Lee J, Goldfine AB: Inflammation and insulin resistance. J Clin Invest 116(7):1793-1801, 2006. (Pubitemid 44033299)
18. Vinayagamoorthi R, Bobby Z, Sridhar MG: Antioxidants preserve redox balance and inhibit c-JunYN-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance. J Endocrinol 197(2):287-296, 2008. (Pubitemid 351696241)
19. Kim JS, Saengsirisuwan V, Sloniger JA, Teachey MK, Henriksen EJ: Oxidant stress and skeletal muscle glucose transport: roles of insulin signaling and p38 MAPK. Free Radic Biol Med 41(5):818-824, 2006. (Pubitemid 44163415)
20. Szeto HH: Mitochondria-targeted cytoprotective peptides for ischemiareperfusion injury. Antioxid Redox Signal 10(3):601-619, 2008.
21. Cho J, Won K, Wu D, Soong Y, Liu S, Szeto HH, Hong MK: Potent mitochondria-targeted peptides reduce myocardial infarction in rats. Coron Artery Dis 18(3):215-220, 2007. (Pubitemid 46608500)
22. Walker HL, Mason AD Jr: A standard animal burn. J Trauma 8(6):1049-1051, 1968.
23. Petri S, Kiaei M, Damiano M, Hiller A, Wille E, Manfredi G, Calingasan NY, Szeto HH, Beal MF: Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis. J Neurochem 98(4):1141-1148, 2006. (Pubitemid 44127789)
24. Fang CH, Li BG, Tiao G, Wang JJ, Fischer JE, Hasselgren PO: The molecular regulation of protein breakdown following burn injury is different in fastand slow-twitch skeletal muscle. Int J Mol Med 1(1):163-169, 1998.
25. Ikezu T, Okamoto T, Yonezawa K, Tompkins RG, Martyn JA: Analysis of thermal injury-induced insulin resistance in rodents. Implication of postreceptor mechanisms. J Biol Chem 272(40):25289-25295, 1997. (Pubitemid 27415719)
26. Dharap SS, Wang Y, Chandna P, Khandare JJ, Qiu B, Gunaseelan S, Sinko PJ, Stein S, Farmanfarmaian A, Minko T: Tumor-specific targeting of an anticancer drug delivery system by LHRH peptide. Proc Natl Acad Sci USA 102(36): 12962-12967, 2005. (Pubitemid 41279472)
27. Pakunlu RI, Wang Y, Tsao W, Pozharov V, Cook TJ, Minko T: Enhancement of the efficacy of chemotherapy for lung cancer by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense: novel multicomponent delivery system. Cancer research 64(17):6214-6224, 2004. (Pubitemid 39129423)
28. Cree MG, Fram RY, Herndon DN, Qian T, Angel C, Green JM, Mlcak R, Aarsland A, Wolfe RR: Human mitochondrial oxidative capacity is acutely impaired after burn trauma. Am J Surg 196(2):234-239, 2008. (Pubitemid 351970524)
29. Biolo G, Fleming RY, Maggi SP, Nguyen TT, Herndon DN, Wolfe RR: Inverse regulation of protein turnover and amino acid transport in skeletal muscle of hypercatabolic patients. J Clin Endocrinol Metab 87(7):3378-3384, 2002. (Pubitemid 34816392)
30. Herndon DN, Tompkins RG: Support of the metabolic response to burn injury. Lancet 363(9424):1895-1902, 2004. (Pubitemid 38748648)
31. Tzika AA, Mintzopoulos D, Mindrinos M, Zhang J, Rahme LG, Tompkins RG: Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle. Int J Mol Med 24(3):387-392, 2009.
32. Gauglitz GG, Halder S, Boehning DF, Kulp GA, Herndon DN, Barral JM, Jeschke MG: Post-burn hepatic insulin resistance is associated with ER stress. Shock 33(3):299-305, 2010.
33. Price J, Zaidi AK, Bohensky J, Srinivas V, Shapiro IM, Ali H: Akt-1 mediates survival of chondrocytes from endoplasmic reticulum-induced stress. J Cell Physiol 222(3):502-508, 2010.
34. Hyoda K, Hosoi T, Horie N, Okuma Y, Ozawa K, Nomura Y: PI3K-Akt inactivation induced CHOP expression in endoplasmic reticulum-stressed cells. Biochem Biophys Res Commun 340(1):286-290, 2006. (Pubitemid 41827678)
35. Lightfoot E Jr, Horton JW, Maass DL, White DJ, McFarland RD, Lipsky PE: Major burn trauma in rats promotes cardiac and gastrointestinal apoptosis. Shock 11(1):29-34, 1999.