Modulating O 2 reactivity in a fungal flavoenzyme: Involvement of aryl-alcohol oxidase Phe-501 contiguous to catalytic histidine

Journal of Biological Chemistry

Volumn 286, Issue 47, 2011, Pages 41105-41114

  Hernández Ortega, Aitor ^a   Lucas, Fátima ^b   Ferreira, Patricia ^c   Medina, Milagros ^c   Guallar, Victor ^b   Martínez, Angel T ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^c UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; AROMATIC RESIDUES; ARYL-ALCOHOL OXIDASE; CATALYTIC EFFICIENCIES; FLAVOENZYMES; FREE DIFFUSION; FUNGAL DEGRADATION; IN-SILICO; KINETIC CONSTANT; NATIVE ENZYMES; OXIDATION DEGREE; SIDE-CHAINS; SITE DIRECTED MUTAGENESIS; TRYPTOPHAN RESIDUES; TURNOVER NUMBER;

CRYSTAL STRUCTURE;

AMINO ACIDS;

ALCOHOL; ARYL ALCOHOL OXIDASE; FLAVOPROTEIN; FUNGAL ENZYME; HISTIDINE; OXYGEN; PHENYLALANINE; QUERCETIN; TRYPTOPHAN; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE; ARYL-ALCOHOL OXIDASE; LIGAND; RIBOFLAVIN DERIVATIVE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SUBSTRATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIMULATION; SITE DIRECTED MUTAGENESIS; STEADY STATE; ALGORITHM; BIOCATALYSIS; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; DIFFUSION; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; MUTATION; OXIDATION REDUCTION REACTION; PLEUROTUS; X RAY CRYSTALLOGRAPHY;

ALCOHOL OXIDOREDUCTASES; ALGORITHMS; BIOCATALYSIS; CATALYTIC DOMAIN; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; DIFFUSION; FLAVINS; HISTIDINE; KINETICS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; OXIDATION-REDUCTION; OXYGEN; PHENYLALANINE; PLEUROTUS;

EID: 81755181712     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.282467     Document Type: Article

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