Oxygen Access to the Active Site of Cholesterol Oxidase through a Narrow Channel Is Gated by an Arg-Glu Pair

Journal of Biological Chemistry

Volumn 276, Issue 32, 2001, Pages 30435-30441

  Coulombe, René ^a   Yue, Kimberley Q ^a   Ghisla, Sandro ^b   Vrielink, Alice ^c  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; CHOLESTEROL; CONFORMATIONS; ENZYME KINETICS; ISOMERIZATION; OXIDATION;

COVALENT BONDS;

BIOCHEMISTRY;

ARGININE; CHOLEST 4 EN 3 ONE; CHOLESTEROL; CHOLESTEROL OXIDASE; FLAVINE ADENINE NUCLEOTIDE; FLAVOPROTEIN; GLUTAMIC ACID; HISTIDINE; ISOENZYME; MONOMER; OXYGEN; STEROID; WATER; RECOMBINANT PROTEIN; RIBOFLAVIN DERIVATIVE;

ARTICLE; BREVIBACTERIUM; BREVIBACTERIUM STEROLICUM; CHANNEL GATING; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME MECHANISM; ENZYME POLYMORPHISM; ENZYME SUBSTRATE COMPLEX; ISOMERISM; OXIDATION; PRIORITY JOURNAL; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; ELECTRON; ENZYMOLOGY; KINETICS; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

BREVIBACTERIUM; BREVIBACTERIUM STEROLICUM;

ARGININE; BINDING SITES; BREVIBACTERIUM; CHOLESTEROL; CHOLESTEROL OXIDASE; ELECTRONS; FLAVINS; GLUTAMIC ACID; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; OXYGEN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 0035839498     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104103200     Document Type: Article

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