UDP-glucose 4, 6-dehydratase activity plays an important role in maintaining cell wall integrity and virulence of Candida albicans

PLoS Pathogens

Volumn 7, Issue 11, 2011, Pages

  Sen, Manimala ^a   Shah, Bhavin ^a   Rakshit, Srabanti ^a   Singh, Vijender ^a,c   Padmanabhan, Bhavna ^a   Ponnusamy, Manikandan ^a   Pari, Koteppa ^b   Vishwakarma, Ram ^b,d   Nandi, Dipankar ^a   Sadhale, Parag P ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b Piramal Enterprises Limited   (India)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; GAMMA INTERFERON; GLYCOSYLPHOSPHATIDYLINOSITOL; HYDROLYASE; PROTEIN GAL102; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCOSE 4,6 DEHYDRATASE; ANTIFUNGAL AGENT; BACTERIAL PROTEIN; DTDPGLUCOSE 4,6 DEHYDRATASE; DTDPGLUCOSE 4,6-DEHYDRATASE; INTERLEUKIN 4; MANNAN; UDP GLUCOSE 4,6 DEHYDRATASE, CANDIDA ALBICANS; UDP-GLUCOSE 4,6-DEHYDRATASE, CANDIDA ALBICANS; URIDINE DIPHOSPHATE GLUCOSE 4 EPIMERASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOFILM; CANDIDA ALBICANS; CANDIDIASIS; CELL WALL; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FUNGAL VIRULENCE; GENE DELETION; IMMUNE RESPONSE; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OPEN READING FRAME; PERITONEUM MACROPHAGE; PHENOTYPE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN MODIFICATION; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CARBOHYDRATE ANALYSIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; INVASIVE CANDIDIASIS; METABOLISM; MOLECULAR GENETICS; MUTATION; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; SEQUENCE ALIGNMENT; VIRULENCE;

CANDIDA ALBICANS;

AMINO ACID SEQUENCE; ANIMALS; ANTIFUNGAL AGENTS; BACTERIAL PROTEINS; BIOFILMS; CANDIDA ALBICANS; CANDIDIASIS; CARBOHYDRATE SEQUENCE; CELL WALL; HYDRO-LYASES; INTERFERON-GAMMA; INTERLEUKIN-4; MACROPHAGES, PERITONEAL; MANNANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE ALIGNMENT; TUMOR NECROSIS FACTOR-ALPHA; UDPGLUCOSE 4-EPIMERASE; VIRULENCE;

EID: 81755177721     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002384     Document Type: Article

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