High-level production of a single chain antibody against anthrax toxin in Escherichia coli by high cell density cultivation

Bioprocess and Biosystems Engineering

Volumn 34, Issue 7, 2011, Pages 811-817

  Jeong, Ki Jun ^a   Rani, Mridula ^b  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Antibody; Escherichia coli; High cell density cultivation; scAb

Indexed keywords

ANTHRAX TOXINS; CELL DENSITY; FED-BATCH CULTIVATION; FEEDING STRATEGIES; HIGH CELL DENSITY CULTURES; HIGH PURITY; HIGH-CELL-DENSITY CULTIVATIONS; HIGH-LEVEL PRODUCTION; PH-STAT; PRODUCTION YIELD; PURIFICATION PROCEDURES; SCAB; SHAKE FLASK CULTIVATIONS; SINGLE-CHAIN ANTIBODIES;

ANTIBODIES; CELLS; DISEASES; ESCHERICHIA COLI; GENE EXPRESSION; PURIFICATION;

CELL CULTURE;

ANTHRAX TOXIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANALYTIC METHOD; ANTIBODY PRODUCTION; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; CELL DENSITY; CELL GROWTH; CONTROLLED STUDY; ESCHERICHIA COLI; FED BATCH CULTURE; GENE EXPRESSION; HIGH CELL DENSITY CULTIVATION; NONHUMAN; PH; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION; SCAB GENE; SOLUBILITY; SPECIES CULTIVATION;

ANTIGENS, BACTERIAL; BACTERIAL TOXINS; BACTERIOLOGICAL TECHNIQUES; CELL COUNT; CULTURE MEDIA; ESCHERICHIA COLI; RECOMBINANT PROTEINS; SINGLE-CHAIN ANTIBODIES;

ESCHERICHIA COLI;

EID: 81755177697     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-011-0531-1     Document Type: Article

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