Identification of framework residues in a secreted recombinant antibody fragment that control production level and localization in Escherichia coli

Journal of Biological Chemistry

Volumn 272, Issue 19, 1997, Pages 12430-12436

  Forsberg, Göran ^a,b   Forsgren, Margareta ^a   Jaki, Maria ^a   Norin, Martin ^a   Sterky, Catharina ^a   Enhörning, Åsa ^a   Larsson, Kerstin ^a   Ericsson, Monica ^a   Björk, Per ^b  

^a Pharmacia and Upjohn ^*  (Sweden)

^b Lund Research Centre   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER ANTIBODY; MONOCLONAL ANTIBODY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIBODY PRODUCTION; ARTICLE; CANCER IMMUNOTHERAPY; CELLULAR DISTRIBUTION; ESCHERICHIA COLI; FERMENTATION; LUNG NON SMALL CELL CANCER; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; BINDING, COMPETITIVE; CANCER VACCINES; CARCINOMA, NON-SMALL-CELL LUNG; CLONING, MOLECULAR; ESCHERICHIA COLI; GENETIC ENGINEERING; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; LUNG NEOPLASMS; MEMBRANE GLYCOPROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPERANTIGENS; TUMOR MARKERS, BIOLOGICAL;

ESCHERICHIA COLI;

EID: 0030912095     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.19.12430     Document Type: Article

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