A simplified process for the manufacture of imagabalin hydrochloride (PD-0332334), an α2δ-ligand for the treatment of generalised anxiety disorder

Organic Process Research and Development

Volumn 15, Issue 6, 2011, Pages 1358-1364

  Birch, Melissa ^a   Challenger, Stephen ^a   Crochard, Jean Philippe ^a   Fradet, David ^a   Jackman, Hayley ^a   Luan, Amy ^a   Madigan, Evelyn ^a   Mathew, Jinu S ^a   McDowall, Neil ^a   Meldrum, Kevin ^a   Gordon, Charles M ^a   Peach, Philip ^a   Yeo, Stephen ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC HYDROGENATION; COST-OF-GOODS; DIASTEREOSELECTIVE HYDROGENATION; ENAMINES; LOW PRESSURES; ONE POT PROCESS; TRIFLUOROACETATES; TWO-STEP PROCESS;

AMMONIUM COMPOUNDS; HYDROGENATION; MANUFACTURE;

LIGANDS;

EID: 81555213051     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op2002326     Document Type: Article

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