Role of poly (ADP) ribose synthetase in lung ischemia - Reperfusion injury

Journal of Heart and Lung Transplantation

Volumn 23, Issue 11, 2004, Pages 1290-1296

  Woolley, Steven M ^a   Farivar, Alexander S ^a   Naidu, Babu V ^a   Salzman, Andrew ^b   Szabo, Csaba ^b   Thomas, Robert ^a   Fraga, Charles ^a   Mulligan, Michael S ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b INOTEK CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; CASPASE 3; CHEMOKINE; CYTOKINE; DNA NUCLEOTIDYLEXOTRANSFERASE; FREE RADICAL; INO 1001; IODINE 125; MYELOPEROXIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NUCLEAR PROTEIN; SUPEROXIDE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL DEATH; CELL ENERGY; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; ISCHEMIA; LEUKOCYTE; LUNG BLOOD VESSEL; LUNG INJURY; LUNG ISCHEMIA; LUNG LAVAGE; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; STAINING;

ANIMALS; INDOLES; MALE; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, LONG-EVANS; REPERFUSION INJURY;

EID: 8144224172     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healun.2003.08.036     Document Type: Article

References (19)

1. Meyers B.F., Lynch J., Trulock E.P., Guthrie T.J., Cooper J.D., Patterson G.A. Lung transplantation a decade of experience. Ann Surg. 230:1999;362-370
2. Eppinger M.J., Jones M.L., Deeb M., et al. Pattern of injury and the role of neutrophils in reperfusion injury of rat lung. J Surg Res. 58:1995;713-718
3. Szabo C., Dawson V.L. Role of poly(ADP-ribose) synthetase in inflammation and ischaemia - reperfusion. Trends Pharmacol Sci. 19:1998;287-298
4. Jagtap P., Soriano F.G., Virag L., et al. Novel phenanthridinone inhibitors of poly (adenosine 5′-diphosphate-ribose) synthetase potent cytoprotective and antishock agents. Crit Care Med. 30:2002;1071-1082
5. Scovassi A.I., Poirier G.G. Poly(ADP-ribosylation) and apoptosis. Mol Cell Biochem. 199:1999;125-137
6. Mabley J.G., Jagtap P., Perretti M., et al. Anti-inflammatory effects of a novel, potent inhibitor of poly(ADP-ribose) polymerase. Inflamm Res. 50:2001;561-569
7. Soriano F.G., Liaudet L., Szabo E., et al. Resistance to acute septic peritonitis in poly(ADP-ribose)polymerase-1-deficient mice. Shock. 17:2002;286-292
8. Liaudet L., Soriano F.G., Szabo E., et al. Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase. Proc Natl Acad Sci USA. 97:2000;10203-10208
9. Szabo G., Bahrle S., Stumpf N., et al. Poly(ADP-ribose) polymerase inhibition reduces reperfusion injury after heart transplantation. Circ Res. 90:2002;100-106
10. Liaudet L., Szabo E., Timashpolsky L., Virag L., Cziraki A., Szabo C. Suppression of poly (ADP-ribose) polymerase activation by 3-aminobenzamide in a rat model of myocardial infarction: long-term morphological and functional consequences. Br J Pharmacol. 133:2001;1424-1430
11. Zingarelli B., Cuzzocrea S., Zsengeller Z., Salzman A.L., Szabo C. Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase. Cardiovasc Res. 36:1997;205-215
12. Abdelkarim G.E., Gertz K., Harms C., et al. Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke. Int J Mol Med. 7:2001;255-260
13. Martin D.R., Lewington A.J., Hammerman M.R., Padanilam B.J. Inhibition of poly(ADP-ribose) polymerase attenuates ischemic renal injury in rats. Am J Physiol Regul Integr Comp Physiol. 279:2000;R1834-R1840
14. Oliver F.J., Menissier-de Murcia J., Nacci C., et al. Resistance to endotoxic shock as a consequence of defective NF-kappa B activation in poly (ADP-ribose) polymerase-1 deficient mice. EMBO J. 18:1999;4446-4454
15. Hassa P.O., Covic M., Hasan S., Imhof R., Hottiger M.O. The enzymatic and DNA binding activities of PARP-1 are not required for NF-kappa B coactivator function. J Biol Chem. 276:2001;45588-45597
16. Krishnadasan B., Naidu B., Rosengart M., et al. Decreased lung ischemia - reperfusion injury in rats after preoperative administration of cyclosporine and tacrolimus. J Thorac Cardiovasc Surg. 123:2002;756-767
17. Naidu B.V., Krishnadasan B., Farivar A.S., et al. Early activation of the alveolar macrophage is critical to the development of lung ischemia reperfusion injury. J Thorac Cardiovasc Surg. 126:2003;200-207
18. Liaudet L., Pacher P., Mabley J.G., et al. Activation of poly(ADP-Ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation. Am J Respir Crit Care Med. 165:2002;372-377
19. Szabo C., Wong H., Bauer P.I., et al. Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways. Int J Oncol. 10:1997;1093-1104