메뉴 건너뛰기




Volumn 17, Issue 11, 2004, Pages 1364-1371

Loss of heterozygosity of chromosome 9p and loss of p16INK4A expression are associated with malignant gastrointestinal stromal tumors

Author keywords

Gastrointestinal stromal tumors; High risk GISTs; KIT; Loss of heterozygosity; Low malignant potential; p16INK4A

Indexed keywords

PROTEIN P16;

EID: 8144222050     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3800199     Document Type: Article
Times cited : (54)

References (31)
  • 1
    • 0036305041 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Answers and questions
    • O'Leary T, Berman JJ. Gastrointestinal stromal tumors: answers and questions. Hum Pathol 2002;33:456-458.
    • (2002) Hum Pathol , vol.33 , pp. 456-458
    • O'Leary, T.1    Berman, J.J.2
  • 2
    • 0023202029 scopus 로고
    • Stromal tumors of the gastrointestinal tract: Myogenic or neurogenic?
    • Hjermstad BM, Sobin LH, Helwig EB. Stromal tumors of the gastrointestinal tract: myogenic or neurogenic? Am J Surg Pathol 1987;11:383-386.
    • (1987) Am J Surg Pathol , vol.11 , pp. 383-386
    • Hjermstad, B.M.1    Sobin, L.H.2    Helwig, E.B.3
  • 3
    • 0034015511 scopus 로고    scopus 로고
    • Molecular insights into the histogenesis and pathogenesis of gastrointestinal stromal tumors
    • Rubin BP, Fletcher JA, Fletcher CD. Molecular insights into the histogenesis and pathogenesis of gastrointestinal stromal tumors. Int J Surg Pathol 2000;8:5-10.
    • (2000) Int J Surg Pathol , vol.8 , pp. 5-10
    • Rubin, B.P.1    Fletcher, J.A.2    Fletcher, C.D.3
  • 4
    • 0031947592 scopus 로고    scopus 로고
    • Gastrointestinal pacemaker cell tumor (GIPACT): Gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal
    • Kindblom LG, Remotti HE, Aldenborg F, et al. Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol 1998;152:1259-1269.
    • (1998) Am J Pathol , vol.152 , pp. 1259-1269
    • Kindblom, L.G.1    Remotti, H.E.2    Aldenborg, F.3
  • 5
    • 0036303804 scopus 로고    scopus 로고
    • Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations
    • Heinrich MC, Rubin BP, Longley BJ, et al. Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations. Hum Pathol 2002;33:484-495.
    • (2002) Hum Pathol , vol.33 , pp. 484-495
    • Heinrich, M.C.1    Rubin, B.P.2    Longley, B.J.3
  • 6
    • 0642368571 scopus 로고    scopus 로고
    • Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
    • Heinrich MC, Corless CL, Demetri GD, et al. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J Clin Oncol 2003;21:4342-4349.
    • (2003) J Clin Oncol , vol.21 , pp. 4342-4349
    • Heinrich, M.C.1    Corless, C.L.2    Demetri, G.D.3
  • 8
    • 0031857113 scopus 로고    scopus 로고
    • CD117: A sensitive marker for gastrointestinal stromal tumors that is more specific than CD34
    • Sarlomo-Rikala M, Kovatich AJ, Barusevicius A, et al. CD117: a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34. Mod Pathol 1998;11:728-734.
    • (1998) Mod Pathol , vol.11 , pp. 728-734
    • Sarlomo-Rikala, M.1    Kovatich, A.J.2    Barusevicius, A.3
  • 9
    • 0032884854 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Recent advances in understanding of their biology
    • Miettinen M, Sarlomo-Rikala M, Lasota J. Gastrointestinal stromal tumors: recent advances in understanding of their biology. Hum Pathol 1999;30:1213-1220.
    • (1999) Hum Pathol , vol.30 , pp. 1213-1220
    • Miettinen, M.1    Sarlomo-Rikala, M.2    Lasota, J.3
  • 10
    • 0036301863 scopus 로고    scopus 로고
    • Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: A review
    • Miettinen M, El Rifai W, Sobin HL, et al. Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review. Hum Pathol 2002;33:478-483.
    • (2002) Hum Pathol , vol.33 , pp. 478-483
    • Miettinen, M.1    El Rifai, W.2    Sobin, H.L.3
  • 11
    • 0036301722 scopus 로고    scopus 로고
    • Diagnosis of gastrointestinal stromal tumors: A consensus approach
    • Fletcher CD, Berman JJ, Corless C, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol 2002;33:459-465.
    • (2002) Hum Pathol , vol.33 , pp. 459-465
    • Fletcher, C.D.1    Berman, J.J.2    Corless, C.3
  • 12
    • 0035810148 scopus 로고    scopus 로고
    • Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
    • Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al. Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 2001;344:1052-1056.
    • (2001) N Engl J Med , vol.344 , pp. 1052-1056
    • Joensuu, H.1    Roberts, P.J.2    Sarlomo-Rikala, M.3
  • 13
    • 0035960428 scopus 로고    scopus 로고
    • Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: A phase I study
    • van Oosterom AT, Judson I, Verweij J, et al. Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study. Lancet 2001;358:1421-1423.
    • (2001) Lancet , vol.358 , pp. 1421-1423
    • Van Oosterom, A.T.1    Judson, I.2    Verweij, J.3
  • 14
    • 0036081738 scopus 로고    scopus 로고
    • Diagnosis of gastrointestinal stromal tumors: A consensus approach
    • Fletcher CD, Herman JJ, Corless C, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Int J Surg Pathol 2002;10:81-89.
    • (2002) Int J Surg Pathol , vol.10 , pp. 81-89
    • Fletcher, C.D.1    Herman, J.J.2    Corless, C.3
  • 15
    • 0036249764 scopus 로고    scopus 로고
    • Altered expression of G1 regulatory proteins in human soft tissue sarcomas
    • Yoo J, Park SY, Kang SJ, et al. Altered expression of G1 regulatory proteins in human soft tissue sarcomas. Arch Pathol Lab Med 2002;126:567-573.
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 567-573
    • Yoo, J.1    Park, S.Y.2    Kang, S.J.3
  • 16
    • 0033669488 scopus 로고    scopus 로고
    • Deletion of the FHIT gene in neoplastic and invasive cervical lesions is related to high-risk HPV infection but is independent of histopathological features
    • Butler D, Collins C, Mabruk M, et al. Deletion of the FHIT gene in neoplastic and invasive cervical lesions is related to high-risk HPV infection but is independent of histopathological features. J Pathol 2000; 192:502-510.
    • (2000) J Pathol , vol.192 , pp. 502-510
    • Butler, D.1    Collins, C.2    Mabruk, M.3
  • 17
    • 0029900130 scopus 로고    scopus 로고
    • DNA copy number losses in chromosome 14: An early change in gastrointestinal stromal tumors
    • El Rifai W, Sarlomo-Rikala M, Miettinen M, et al. DNA copy number losses in chromosome 14: an early change in gastrointestinal stromal tumors. Cancer Res 1996;56:3230-3233.
    • (1996) Cancer Res , vol.56 , pp. 3230-3233
    • El Rifai, W.1    Sarlomo-Rikala, M.2    Miettinen, M.3
  • 18
    • 0036242273 scopus 로고    scopus 로고
    • Biological and clinical significance of cytogenetic abnormalities in low-risk and high-risk gastrointestinal stromal tumors
    • Gunawan B, Bergmann F, Hoer J, et al. Biological and clinical significance of cytogenetic abnormalities in low-risk and high-risk gastrointestinal stromal tumors. Hum Pathol 2002;33:316-321.
    • (2002) Hum Pathol , vol.33 , pp. 316-321
    • Gunawan, B.1    Bergmann, F.2    Hoer, J.3
  • 19
    • 0036806406 scopus 로고    scopus 로고
    • Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. Gastrointestinal stromal tumors
    • Sandberg AA, Bridge JA. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. Gastrointestinal stromal tumors. Cancer Genet Cytogenet 2002;135:1-22.
    • (2002) Cancer Genet Cytogenet , vol.135 , pp. 1-22
    • Sandberg, A.A.1    Bridge, J.A.2
  • 20
    • 0034661189 scopus 로고    scopus 로고
    • Loss of 14q and 22q in gastrointestinal stromal tumors (pacemaker cell tumors)
    • Breiner JA, Meis-Kindblom J, Kindblom LG, et al. Loss of 14q and 22q in gastrointestinal stromal tumors (pacemaker cell tumors). Cancer Genet Cytogenet 2000;120:111-116.
    • (2000) Cancer Genet Cytogenet , vol.120 , pp. 111-116
    • Breiner, J.A.1    Meis-Kindblom, J.2    Kindblom, L.G.3
  • 21
    • 0033980085 scopus 로고    scopus 로고
    • Putative chromosomal deletions on 9p, 9q and 22q occur preferentially in malignant gastrointestinal stromal tumors
    • Kim NG, Kim JJ, Ahn JY, et al. Putative chromosomal deletions on 9p, 9q and 22q occur preferentially in malignant gastrointestinal stromal tumors. Int J Cancer 2000;85:633-638.
    • (2000) Int J Cancer , vol.85 , pp. 633-638
    • Kim, N.G.1    Kim, J.J.2    Ahn, J.Y.3
  • 22
    • 0035397627 scopus 로고    scopus 로고
    • Chromosomal aberrations in malignant gastrointestinal stromal tumors: Correlation with c-KIT gene mutation
    • Debiec-Rychter M, Lasota J, Sarlomo-Rikala M, et al. Chromosomal aberrations in malignant gastrointestinal stromal tumors: correlation with c-KIT gene mutation. Cancer Genet Cytogenet 2001;128:24-30.
    • (2001) Cancer Genet Cytogenet , vol.128 , pp. 24-30
    • Debiec-Rychter, M.1    Lasota, J.2    Sarlomo-Rikala, M.3
  • 23
    • 0033387158 scopus 로고    scopus 로고
    • Loss of heterozygosity at 1p36 predicts poor prognosis in gastrointestinal stromal/smooth muscle tumors
    • O'Leary T, Ernst S, Przygodzki R, et al. Loss of heterozygosity at 1p36 predicts poor prognosis in gastrointestinal stromal/smooth muscle tumors. Lab Invest 1999;79:1461-1467.
    • (1999) Lab Invest , vol.79 , pp. 1461-1467
    • O'Leary, T.1    Ernst, S.2    Przygodzki, R.3
  • 24
    • 0035332255 scopus 로고    scopus 로고
    • Consistent DNA losses on the short arm of chromosome 1 in a series of malignant gastrointestinal stromal tumors
    • Derre J, Lagace R, Terrier P, et al. Consistent DNA losses on the short arm of chromosome 1 in a series of malignant gastrointestinal stromal tumors. Cancer Genet Cytogenet 2001;127:30-33.
    • (2001) Cancer Genet Cytogenet , vol.127 , pp. 30-33
    • Derre, J.1    Lagace, R.2    Terrier, P.3
  • 25
    • 0034660868 scopus 로고    scopus 로고
    • DNA sequence copy number changes in gastrointestinal stromal tumors: Tumor progression and prognostic significance
    • El Rifai W, Sarlomo-Rikala M, Andersson LC, et al. DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance. Cancer Res 2000;60:3899-3903.
    • (2000) Cancer Res , vol.60 , pp. 3899-3903
    • El Rifai, W.1    Sarlomo-Rikala, M.2    Andersson, L.C.3
  • 26
    • 13344259999 scopus 로고    scopus 로고
    • A comprehensive genetic map of the human genome based on 5,264 microsatellites
    • Dib C, Faure S, Fizames C, et al. A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 1996;380:152-154.
    • (1996) Nature , vol.380 , pp. 152-154
    • Dib, C.1    Faure, S.2    Fizames, C.3
  • 27
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • Nobori T, Miura K, Wu DJ, et al. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 1994;368:753-756.
    • (1994) Nature , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3
  • 28
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
    • Hannon GJ, Beach D. p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature 1994; 371:257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 29
    • 0028121279 scopus 로고
    • A cell cycle regulator potentially involved in genesis of many tumor types
    • Kamb A, Gruis NA, Weaver-Feldhaus J, et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science 1994;264:436-440.
    • (1994) Science , vol.264 , pp. 436-440
    • Kamb, A.1    Gruis, N.A.2    Weaver-Feldhaus, J.3
  • 30
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993;366:704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 31
    • 0038135029 scopus 로고    scopus 로고
    • High prognostic value of p16INK4 alterations in gastrointestinal stromal tumors
    • Schneider-Stock R, Boltze C, Lasota J, et al. High prognostic value of p16INK4 alterations in gastrointestinal stromal tumors. J Clin Oncol 2003;21:1688-1697.
    • (2003) J Clin Oncol , vol.21 , pp. 1688-1697
    • Schneider-Stock, R.1    Boltze, C.2    Lasota, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.