Loss of 14q and 22q in gastrointestinal stromal tumors (pacemaker cell tumors)

Cancer Genetics and Cytogenetics

Volumn 120, Issue 2, 2000, Pages 111-116

  Breiner, Julie A ^a   Meis Kindblom, Jeanne ^b   Kindblom, Lars Gunnar ^b   McComb, Erin ^a   Liu, Jian ^a   Nelson, Marilu ^a   Bridge, Julia A ^a,c  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CHROMOSOME 1; CHROMOSOME 14Q; CHROMOSOME 22Q; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME LOSS; CHROMOSOME REARRANGEMENT; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GASTROINTESTINAL TUMOR; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; MALE; MICROSCOPY; MOLECULAR GENETICS; PACEMAKER NERVE CELL; PATHOLOGY; PHENOTYPE; PRIORITY JOURNAL; STROMA; TUMOR SUPPRESSOR GENE;

ADULT; AGED; ANTIGENS, CD34; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 22; FEMALE; GASTROINTESTINAL NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; KI-67 ANTIGEN; MALE; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-KIT; STROMAL CELLS;

EID: 0034661189     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(00)00212-0     Document Type: Article

References (33)

1. Lauwers GY, Erlandson RA, Casper ES, Brennan MF, Woodruff JM (1993): Gastrointestinal autonomic nerve tumors: a clinicopathological, immunohistochemical and ultrastructural study of 12 cases. Am J Surg Pathol 17:887-897.
2. Batts KP, Barwick KW (1996): The esophagus and stomach. In: The Difficult Diagnosis in Surgical Pathology, 1st Ed. M Weidner, ed. WB Saunders, Philadelphia, pp.177-206.
3. th Ed. CV Mosby, St. Louis.
4. rd Series. Armed Forces Institute of Pathology, Washington, DC, pp. 405-456.
5. Miettinen M, Martti V, Sarlomo-Rikala M (1995): Gastrointestinal stromal tumors - value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas. Am J Surg Pathol 19:207-216.
6. Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, Kawano K, Hanada M, Kurata A, Takeda M, Muhammad-Tunio G, Matsuzawa Y, Kanakura Y, Shinomura Y, Kitamura Y (1998): Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 279:577-580.
7. Kindblom LG, Remotti HE, Aldenborg F, Meis-Kindblom JM (1998): Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol 152:1259-1269.
8. Huizinga JD, Thuneberg L, Kluppel M, Malysz J, Mikkelsen HB, Bernstein A (1995): W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373:347-349.
9. Mikhael AI, Bacchi CE, Zarbo RJ, Ma CK, Gown AM (1994): CD34 expression in stromal tumors of the gastrointestinal tract. Appl Immunohistochem 2:89-93.
10. van de Rijn M, Hendrickson MR, Rouse RV (1994): CD34 expression by gastrointestinal tract stromal tumors. Hum Pathol 25:766-771.
11. Marci V, Casorzo L, Sarotto I, Dogliani N, Milazzo MG, Risio M (1998): Gastrointestinal stromal tumor, uncommitted type, with monosomies 14 and 22 as the only chromosomal abnormalities. Cancer Genet Cytogenet 102:135-138.
12. Amin MB, Ma CK, Linden MD, Kubus JJ, Zarbo RJ (1993): Prognostic value of proliferating cell nuclear antigen index in gastric stromal tumors. Correlation with mitotic count and clinical outcome. Am J Clin Pathol 100:428-432.
13. Bridge JA, DeBoer J, Walker CW, Neff JR (1995): Translocation t(3;12)(q28;q14) in parosteal lipoma. Genes Chromosom Cancer 12:70-72.
14. ISCN (1995): An International System for Human Cytogenetic Nomenclature. F Mitelman, ed. S. Karger, Basel.
15. Delattre O, Zucman J, Plougastel B, Desmaze C, Melot T, Peter M, Kovar H, Joubert I, de Jong P, Rouleau G, Aurias A, Thomas G (1992): Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature 359:162-165.
16. Zucman J, Delattre O, Desmaze C, Plougastel B, Joubert I, Melot T, Peter M, de Jong P, Rouleau G, Aurias A, Thomas G (1992): Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoint. Genes Chromosom Cancer 5:271-277.
17. Bridge JA, Fidler ME, Neff JR, Degenhardt J, Wang M, Walker C, Dorfman HD, Baker KS, Seemayer TA (1999): Adamantinoma-like Ewing's sarcoma: genomic confirmation, phenotypic drift. Am J Surg Pathol 23:159-165.
18. Pedeutour F, Quade BJ, Weremowica S, Dal Cin P, Ali S, Morton CC (1998): Localization and expression of the human estrogen receptor beta gene in uterine leiomyomata. Genes Chromosom Cancer 23:361-366.
19. Monihan JM, Carr NJ, Sobin LH (1994): CD34 immunoexpression in stromal tumours of the gastrointestinal tract and in mesenteric fibromatoses. Histopathology 25:469-473.
20. El-Rifai W, Sarlomo-Rikala M, Miettinen M, Knuutila S, Andersson LC (1996): DNA copy number losses in chromosome 14: an early change in GI stromal tumors. Cancer Res 56:3230-3233.
21. Sarlomo-Rikala M, El-Rifai W, Lahtinen T, Andersson LC, Miettinen M, Knuutila S (1998): Different patterns of DNA copy number changes in gastrointestinal stromal tumors, leiomyomas, and schwannomas. Hum Pathol 29:476-481.
22. Mark J (1976): G-band analyses of a human intestinal leiomyosarcoma. Acta Path Microbiol Scand Sect A 84:538-540.
23. Dal Cin P, Boghosian L, Sandberg AA (1988): Cytogenetic findings in leiomyosarcoma of the small bowel. Cancer Genet Cytogenet 30:285-288.
24. Sait SNJ, Dal Cin P, Sandberg AA (1988): Consistent chromosome changes in leiomyosarcoma. Cancer Genet Cytogenet 35:47-50.
25. Boghosian L, Dal Cin P, Turc-Carel C, Rao U, Karakousis C, Sait SJ, Sandberg AA (1989): Three possible cytogenetic subgroups of leiomyosarcoma. Cancer Genet Cytogenet 43:39-49.
26. Mark J, Wedell B, Dahlenfors R, Havel G (1989): Cytogenetic observations in a human gastric leiomyosarcoma. Cancer Genet Cytogenet 37:215-220.
27. Bardi G, Johansson B, Pandis N, Heim S, Mandahl N, Bak-Jensen E, Frederiksen H, Andren-Sandberg A, Mitelman F (1992): Recurrent chromosome aberrations in abdominal smooth muscle tumors. Cancer Genet Cytogenet 62:43-46.
28. Sreekantaiah C, Davis JR, Sandberg AA (1993): Chromosomal abnormalities in leiomyosarcomas. Am J Pathol 142:293-305.
29. Saunders AL, Meloni AM, Chen Z, Sandberg AA, Lauwers GY (1996): Two cases of low-grade gastric leiomyosarcoma with monosomy 14 as the only change. Cancer Genet Cytogenet 90:184-185.
30. Bergmann F, Gunawan B, Hermanns B, Höer J, Schumpelick V, Füzesi L (1998): Cytogenetic and morphologic characteristics of gastrointestinal stromal tumors. Recurrent rearrangement of chromosome 1 and losses of chromosomes 14 and 22 as common anomalies. Verh Dtsch Ges Pathol 82:275-278.
31. Sandberg AA, Bridge JA (1994): The Cytogenetics of Bone and Soft Tissue Tumors. RG Landes, Florida.
32. Mertens F, Rydholm A, Bauer HFC, Limon J, Nedoszytoko B, Szadowska A, Willen H, Heim S, Mitelman F, Mandahl N (1995): Cytogenetic findings in malignant peripheral nerve sheath tumors. Int J Cancer 61:793-798.
33. Rao UNM, Surti U, Hoffner L, Yaw K (1996): Cytogenetic and histologic correlation of peripheral nerve sheath tumors of soft tissue. Cancer Genet Cytogenet 88:17-25.