The protooncogene c-kit and c-kit ligand in human disease

Journal of Allergy and Clinical Immunology

Volumn 100, Issue 4, 1997, Pages 435-440

  Vliagoftis, Harissios ^a   Worobec, Alexandra S ^a   Metcalfe, Dean D ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR;

CLINICAL TRIAL; GERM CELL; HEMATOPOIETIC STEM CELL; HUMAN; LEUKEMIA; MAST CELL; MASTOCYTOSIS; MELANOCYTE; NONHUMAN; PANCYTOPENIA; PIEBALDISM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030871079     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(97)70131-3     Document Type: Article

References (11)

1. Lev S, Blechman JM, Givol D, Yarden Y. Steel factor and c-kit protooncogene: genetic lessons in signal transduction. Crit Rev Oncog 1994;5:141-68.
2. Kitayama H, Kanakura Y, Furitsu T, Tsujimura T, Oritani K, Ikeda H, et al. Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines. Blood 1995;85:790-8.
3. Spritz RA, Hearing VJ. Genetic disorders of pigmentation. Adv Hum Genet 1994;22:1-45.
4. Longley BJ, Morganroth GS, Tyrrell L, Ding TG, Anderson DM, Williams DE, et al. Altered metabolism of mast-cell growth factor (c-kit ligand) in cutaneous mastocytosis. N Engl J Med 1993;328:1302-7.
5. Rottem M, Okada T, Goff JP, Metcalfe DD. Mast cells cultured from the peripheral blood of normal donors and patients with mastocytosis originate from a CD34+/Fc epsilon RI-cell population. Blood 1994;84:2489-96.
6. Nagata H, Worobec AS, Oh CK, Chowdhury BA, Tannenbaum S, Suzuki Y, et al. Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder. Proc Natl Acad Sci USA 1995;92:10560-4.
7. Kanakura Y, Furitsu T, Tsujimura T, Butterfield JH, Ashway LK, Ikeda H, et al. Activating mutations of the c-kit proto-oncogene in a human mast cell leukemia cell line. Leukemia 1994;8(suppl 1):518-22.
8. Kitayama H, Tsujimura T, Matsumura I, Oritani K, Ikeda H, Ishikawa J, et al. Neoplastic transformation of normal hematopoietic cells by constitutively activating mutations of c-kit receptor tyrosine kinase. Blood 1996;88:995-1004.
9. Longley BJ, Tyrrell L, Lu SZ, Ma YS, Langley K, Ding TG, et al. Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm. Nat Genet 1996;12:312-4.
10. Pignon JM, Giraudier S, Duquesnoy F, Jouault H, Imbert M, Vainchenker W, et al. A new c-kit mutation in a case of aggressive mast cell disease. Br J Haematol 1997;96:374-6.
11. Costa JJ, Demetri CD, Harrist TJ, Dvorak AM, Hayes DF, Merika EA, et al. Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo. J Exp Med 1996;183:2681-6.