-
8
-
-
0032055223
-
Gastrointestinal stromal tumor, uncommitted type, with monosomies 14 and 22 as the only chromosomal abnormalities
-
(1998)
Cancer Genet Cytogenet
, vol.102
, pp. 135-138
-
-
Marci, V.1
Casorzo, L.2
Sarotto, I.3
Dogliani, N.4
Milazzo, M.G.5
Risio, M.6
-
9
-
-
0000244046
-
Evaluation of the safety and efficacy of an oral molecularly-targeted therapy, STI571, in patients (Pts) with unresectable or metastatic gastrointestinal stromal tumors (GISTS) expressing C-KIT (CD117)
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Blanke, C.D.1
von Mehren, M.2
Joensuu, H.3
Roberts, P.J.4
Fisenberg, B.5
Heinrich, M.6
Druker, B.7
Tuveson, D.8
Dmitrijevic, S.9
Silberman, S.L.10
Demetri, G.O.11
-
10
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with gastrointestinal stromal tumor
-
(2001)
N Engl J Med
, vol.344
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
Andersson, L.C.4
Tervahar- tiala, P.5
Tuveson, D.6
Silberman, S.L.7
Capdeville, R.8
Dimitrijevic, S.9
Druker, B.10
Demetri, G.D.11
-
11
-
-
0035854033
-
Researchers optimistic about sea change treatment
-
(2001)
JAMA
, vol.285
, pp. 2841-2842
-
-
Stephenson, J.1
-
12
-
-
0002499759
-
STI 571, an active drug in metastatic gastrointestinal stromal tumors (GIST), an EORTC phase I study
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Van Oosterom, A.T.1
Judson, I.2
Verweij, J.3
DiPaola, E.4
van Glabbeke, M.5
Dimitrijevic, S.6
Nielsen, O.7
-
18
-
-
0035890740
-
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors
-
(2001)
Cancer Res
, vol.61
, pp. 8118-8121
-
-
Rubin, B.P.1
Singer, S.2
Tsao, C.3
Duensing, A.4
Lux, M.L.5
Ruiz, R.6
Hibbard, M.K.7
Chen, C.J.8
Xiao, S.9
Tuveson, D.A.10
Demetri, G.D.11
Fletcher, C.D.M.12
Fletcher, J.A.13
-
22
-
-
84965085738
-
Bizarre smooth muscle tumors of the stomach
-
(1962)
Cancer
, vol.15
, pp. 400-409
-
-
Stout, A.P.1
-
31
-
-
0032602423
-
Mesenchymal tumors of the gastrointestinal tract; A paradise for acronyms (STUMP, GIST, GANT, and now GIPACT), implication of the c-kit in genesis, and yet another of the many emerging roles of the interstitial cells of Cajal in the pathogenesis of gastrointestinal diseases?
-
(1999)
Adv Anat Pathol
, vol.6
, pp. 19-40
-
-
Chan, J.K.C.1
-
32
-
-
0034883994
-
Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus. A clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases
-
(2001)
Am J Surg Pathol
, vol.25
, pp. 1121-1133
-
-
Miettinen, M.1
Furlong, M.2
Sarlomo-Rikala, M.3
Burke, A.4
Sobin, L.H.5
Lasota, J.6
-
33
-
-
0034779713
-
Mesenchymal tumors of muscularis mucosae of colon and rectum are benign leiomyomas that should be separated from gastrointestinal stromal tumors-clinicopathologic and immunohistochemical study of eighty-eight cases
-
(2001)
Mod Pathol
, vol.14
, pp. 950-956
-
-
Miettinen, M.1
Sarlomo-Rikala, M.2
Sobin, L.H.3
-
37
-
-
0026543765
-
Small intestinal stromal tumors with skeinoid fibers. Clinicopathological, immunohistochemical, and ultrastructural investigations
-
(1992)
Am J Surg Pathol
, vol.16
, pp. 145-155
-
-
Min, K.W.1
-
38
-
-
0009361657
-
-
Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J. Esophageal stromal tumors. A clinicopathologic, immunohistochemical, and molecular genetic study of 17 cases and comparison with esophageal leiomyomas and leiomyosarcomas. Am J Surg Pathol 2000;24:211-22.
-
-
-
-
60
-
-
15644363454
-
Gain-of-function of c-kit in human gastrointestinal stromal tumors
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
Hashimoto, K.4
Nishida, T.5
Ishiguro, S.6
Kawano, K.7
Hanada, M.8
Kurata, A.9
Takeda, M.10
Tunio, G.M.11
Matsuzawa, Y.12
Kanakura, Y.13
Shinomura, Y.14
Kitamura, Y.15
-
65
-
-
0030017762
-
A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract
-
(1996)
Gastroenterology
, vol.111
, pp. 492-515
-
-
Sanders, K.M.1
-
70
-
-
0025001894
-
Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor
-
(1990)
Cell
, vol.63
, pp. 213-224
-
-
Zsebo, K.M.1
Williams, D.A.2
Geissler, E.N.3
Broudy, V.C.4
Martin, F.H.5
Atkins, H.L.6
Hsu, R.Y.7
Birkett, N.C.8
Okino, K.H.9
Murdock, D.C.10
Jacobsen, F.W.11
Langley, K.E.12
Smith, K.A.13
Takeishi, T.14
Cattanach, B.M.15
Galli, S.J.16
Suggs, S.V.17
-
80
-
-
2742529418
-
Human proto- ncogene c-kit; a new cells surface receptor tyrosine kinase for an unidentified ligand
-
(1987)
EMBO
, vol.6
, pp. 3341-3351
-
-
Yarden, Y.1
Kuang, W.J.2
Yang-Feng, T.3
Coussens, L.4
Munemitsu, S.5
Dull, T.J.6
Chen, E.7
Schlessinger, J.8
Francke, U.9
Ullrich, A.10
-
81
-
-
0025013548
-
Identification of a ligand for the c-kit proto-oncogene
-
(1990)
Cell
, vol.63
, pp. 167-174
-
-
Williams, D.E.1
Eisenman, J.2
Baird, A.3
Rauch, C.4
Van Ness, K.5
March, C.J.6
Park, L.S.7
Martin, U.8
Mochizuki, D.Y.9
Boswell, H.S.10
Burgess, G.S.11
Cosman, D.12
Lyman, S.D.13
-
82
-
-
0028209474
-
Preferential localization of c-kit product in tissue mast cells, basal cells of skin, epithelial cells of breast, small cell lung carcinoma and seminoma/dysgerminoma in human; immunohistochemical study on formalin-fixed, paraffin-embedded tissues
-
(1994)
Virchows Arch
, vol.424
, pp. 135-141
-
-
Tsuura, Y.1
Hiraki, H.2
Watanabe, K.3
Igarashi, S.4
Shimamura, K.5
Fukuda, T.6
Suzuki, T.7
Seito, T.8
-
85
-
-
0022541219
-
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
-
(1986)
Nature
, vol.323
, pp. 226-232
-
-
Yarden, Y.1
Escobedo, J.A.2
Kuang, W.J.3
Yang-Feng, T.L.4
Daniel, T.O.5
Tremble, P.M.6
Chen, E.Y.7
Ando, M.E.8
Harkins, R.N.9
Francke, U.10
Fried, V.A.11
Ullrich, A.12
Williams, L.T.13
-
86
-
-
0022542014
-
Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus
-
(1986)
Nature
, vol.320
, pp. 277-280
-
-
Coussens, L.1
Van Beveren, C.2
Smith, D.3
Chen, E.4
Mitchell, R.L.5
Isacke, C.M.6
Verma, I.M.7
Ullrich, A.8
-
87
-
-
0025065459
-
Primary structure and functional expression of rat and human stem cell factor DNAs
-
(1990)
Cell
, vol.63
, pp. 203-211
-
-
Martin, F.H.1
Suggs, S.V.2
Langley, K.E.3
Lu, H.S.4
Ting, J.5
Okino, K.H.6
Morris, C.F.7
McNiece, I.K.8
Jacobsen, F.W.9
Mendiaz, E.A.10
Birkett, N.C.11
Smith, K.A.12
Johnson, M.J.13
Parker, V.P.14
Flores, J.C.15
Patel, A.C.16
Fisher, E.F.17
Erjavec, H.O.18
Herrera, J.19
Wypych, J.20
Sachdev, R.K.21
Pope, J.A.22
Leslie, I.23
Wen, D.24
Lin, C.H.25
Cuppies, R.L.26
Zsebo, K.M.27
more..
-
88
-
-
0025077796
-
The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus
-
(1990)
Cell
, vol.63
, pp. 225-233
-
-
Huang, E.1
Nocka, K.2
Beier, D.R.3
Chu, T.Y.4
Buch, J.5
Lahm, H.W.6
Wellner, D.7
Leder, P.8
Besmer, P.9
-
89
-
-
0027218845
-
From white spots to stem cells; the role of the Kit receptor in mammalian development
-
(1993)
Trends Genet
, vol.9
, pp. 285-290
-
-
Fleischman, R.A.1
-
94
-
-
0026066984
-
A specific combination of substrates is involved in signal transduction by the kit-encoded receptor
-
(1991)
EMBO J
, vol.10
, pp. 647-654
-
-
Lev, S.1
Givol, D.2
Yarden, Y.3
-
99
-
-
0025755422
-
c-src complexes, and PI3-kinase
-
(1991)
Cell
, vol.65
, pp. 91-104
-
-
Otsu, M.1
Hiles, I.2
Gout, I.3
Fry, M.J.4
Ruiz-Larrea, F.5
Panayotou, G.6
Thompson, A.7
Dhand, R.8
Hsuan, J.9
Totty, N.10
Smith, A.D.11
Morgan, S.J.12
Courtneidge, S.A.13
Parker, P.J.14
Waterfield, M.D.15
-
100
-
-
0025921611
-
Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases
-
(1991)
Cell
, vol.65
, pp. 83-90
-
-
Skolnik, E.Y.1
Margolis, B.2
Mohammadi, M.3
Lowenstein, E.4
Fischer, R.5
Drepps, A.6
Ullrich, A.7
Schlessinger, J.8
-
102
-
-
0018344526
-
Decreased production of mast cells in S1/S1d anemic mice
-
(1979)
Blood
, vol.53
, pp. 495-497
-
-
Kitamura, Y.1
Go, S.2
-
103
-
-
0018625422
-
Hereditary anemia of the mouse; A review for geneticists
-
(1979)
Adv Gen
, vol.20
, pp. 357-359
-
-
Russell, E.S.1
-
104
-
-
0029101721
-
Disturbed intestinal movement, bile reflux to the stomach, and deficiency of c-kit-expressing cells in Ws/Ws mutant rats
-
(1995)
Gastroenterology
, vol.109
, pp. 456-464
-
-
Isozaki, K.1
Hirota, S.2
Nakama, A.3
Miyagawa, J.I.4
Shimomura, Y.5
Xu, Z.6
Nomura, S.7
Kitamura, Y.8
-
105
-
-
0027359443
-
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product
-
(1993)
J Clin Invest
, vol.92
, pp. 1736-1744
-
-
Furitsu, T.1
Tsujimura, T.2
Tono, T.3
Ikeda, H.4
Kitayama, H.5
Koshimizu, U.6
Sugahara, H.7
Butterfield, J.H.8
Ashman, L.K.9
Kanayama, Y.10
Matsuzawa, Y.11
Kitamura, Y.12
Kanakura, Y.13
-
106
-
-
0028229976
-
Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation
-
(1994)
Blood
, vol.83
, pp. 2619-2626
-
-
Tsujimura, T.1
Furitsu, T.2
Morimoto, M.3
Isozaki, K.4
Nomura, S.5
Matsuzawa, Y.6
Kitamura, Y.7
Kanakura, Y.8
-
107
-
-
0028968751
-
Substitution of an aspartic acid results in constitutive activation of c-kit receptor tyrosine kinase in a rat tumor mast cell line RBL-2H3
-
(1995)
Int Arch Allergy Immunol
, vol.106
, pp. 377-385
-
-
Tsujimura, T.1
Furitsu, T.2
Morimoto, M.3
Kanayama, Y.4
Nomura, S.5
Matsuzawa, Y.6
Kitamura, Y.7
Kanakura, Y.8
-
108
-
-
0030032943
-
Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain
-
(1996)
Blood
, vol.87
, pp. 273-283
-
-
Tsujimura, T.1
Morimoto, M.2
Hashimoto, K.3
Moriyama, Y.4
Kitayama, H.5
Matsuzawa, Y.6
Kitamura, Y.7
Kanakura, Y.8
-
110
-
-
0031791026
-
A novel gain-of-function of c-kit gene in gastrointestinal stromal tumors
-
(1998)
Gastroenterology
, vol.115
, pp. 1090-1095
-
-
Nakahara, M.1
Isozaki, K.2
Hirota, S.3
Miyagawa, J.I.4
Hase-Sawada, N.5
Taniguchi, M.6
Nishida, T.7
Kanayama, S.8
Kitamura, Y.9
Shinomura, Y.10
Matsuzawa, Y.11
-
116
-
-
0027391997
-
Expression of the c-kit protein in human solid tumors and in corresponding fetal and adult normal tissues
-
(1993)
Am J Pathol
, vol.142
, pp. 339-346
-
-
Matsuda, R.1
Takahashi, T.2
Nakamura, S.3
Sekido, Y.4
Nishida, K.5
Seto, M.6
Seito, T.7
Sugiura, T.8
Ariyoshi, Y.9
-
118
-
-
0009013631
-
Somatic c-KIT activating mutations in urticaria pigmentosa and aggressive mastocytosis; establishment of clonality in a human mast cell neoplasm
-
(1996)
Nature Genet
, vol.12
, pp. 312-314
-
-
Longley, B.J.1
Tyrrell, L.2
Lu, S.Z.3
Ma, Y.S.4
Langley, K.5
Ding, T.6
Duffy, T.7
Jacobs, P.8
Tang, L.H.9
Modlin, I.10
-
120
-
-
0033883060
-
KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors
-
(2000)
Am J Pathol
, vol.156
, pp. 791-795
-
-
Lux, M.L.1
Rubion, B.P.2
Biase, T.L.3
Chen, C.J.4
Maclure, T.5
Demetri, G.6
Xiao, S.7
Singer, S.8
Fletcher, C.D.M.9
Fletcher, J.A.10
-
123
-
-
0033820064
-
Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases
-
(2000)
Am J Pathol
, vol.157
, pp. 1091-1095
-
-
Lasota, J.1
Wozniak, A.2
Sarloma-Rikala, M.3
Rys, J.4
Kordek, R.5
Nassar, A.6
Sobin, L.H.7
Miettinen, M.8
-
127
-
-
0033756775
-
Specific mutation in exon 11 of c-kit proto-oncogene in a malignant gastrointestinal stromal tumor of the rectum
-
(2000)
J Gastroenterol
, vol.35
, pp. 779-783
-
-
Yamaguchi, M.1
Miyaki, M.2
Iijima, T.3
Matsumoto, T.4
Kuzume, M.5
Matsumiya, A.6
Endo, Y.7
Sanada, Y.8
Kumada, K.9
-
129
-
-
0033199890
-
Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors
-
(1999)
Cancer Res
, vol.59
, pp. 4297-4300
-
-
Taniguchi, M.1
Nishida, T.2
Hirota, S.3
Isozaki, K.4
Ito, T.5
Nomura, T.6
Matsuda, H.7
Kitamura, Y.8
-
132
-
-
0031848146
-
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene
-
(1998)
Nature Genet
, vol.19
, pp. 323-324
-
-
Nishida, T.1
Hirota, S.2
Taniguchi, M.3
Hashimoto, K.4
Isozaki, K.5
Nakamura, H.6
Kanakura, Y.7
Tanaka, T.8
Takabayashi, A.9
Matsuda, H.10
Kitamura, Y.11
-
134
-
-
0035174752
-
Familial gastrointestinal stromal tumor with hyperpigmentation; association with a germline mutation of the c-kit gene
-
(2001)
Gastroenterology
, vol.120
, pp. 210-215
-
-
Maeyama, H.1
Hidaka, E.2
Ota, H.3
Minami, S.4
Kajiyama, M.5
Kuraishi, A.6
Mori, H.7
Matsuda, Y.8
Wada, S.9
Sodeyama, H.10
Nakata, S.11
Kawamura, N.12
Hata, S.13
Watanabe, M.14
Iijima, Y.15
Katsuyama, T.16
-
137
-
-
0033199890
-
Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors
-
(1999)
Cancer Res
, vol.59
, pp. 4297-4300
-
-
Taniguchi, M.1
Nishida, T.2
Hirota, S.3
Isozaki, K.4
Ito, T.5
Nomura, T.6
Matsuda, H.7
Kitamura, Y.8
-
140
-
-
17144470837
-
Growth stimulation of colorectal carcinoma cells via the c-kit receptor is inhibited by TGF-beta 1
-
(1997)
J Cell Physiol
, vol.172
, pp. 1-11
-
-
Bellone, G.1
Silvestri, S.2
Artusio, E.3
Tibaudi, D.4
Turletti, A.5
Geuna, M.6
Giachino, C.7
Valente, G.8
Emanuelli, G.9
Rodeck, U.10
-
157
-
-
0026758315
-
Recurrent chromosome aberrations in abdominal smooth muscle tumors
-
(1992)
Cancer Genet Cytogenet
, vol.62
, pp. 43-46
-
-
Bardi, G.1
Johansson, B.2
Pandis, N.3
Heim, S.4
Mandahl, N.5
Bak-Jensen, E.6
Frederiksen, H.7
Andrén-Sandberg8
Mitelman, F.9
-
159
-
-
0031944451
-
Different patterns of DNA copy number changes in gastrointestinal stromal tumors, leiomyomas, and schwan- nomas
-
(1998)
Hum Pathol
, vol.29
, pp. 476-481
-
-
Sarlomo-Rikala, M.1
El-Rifai, W.2
Lahtinen, T.3
Andersson, L.C.4
Miettinen, M.5
Knuutila, S.6
-
160
-
-
0034525682
-
Allelic loss of 14q and 22q, NF2 mutation, and genetic instability occur independently of c-kit mutation in gastrointestinal stromal tumor
-
(2000)
Jpn J Cancer Res
, vol.91
, pp. 1241-1249
-
-
Fukasawa, T.1
Chong, J.M.2
Sakurai, S.3
Koshiishi, N.4
Ikeno, R.5
Tanaka, A.6
Matsumoto, Y.7
Hayashi, Y.8
Koike, M.9
Fukayama, M.10
-
161
-
-
0029060246
-
Cytogenetic findings in malignant peripheral nerve sheath tumors
-
(1995)
Int J Cancer
, vol.61
, pp. 793-798
-
-
Mertens, F.1
Rydholm, A.2
Bauer, H.F.C.3
Limon, J.4
Nedoszytoko, B.5
Szadowska, A.6
Willén, H.7
Heim, S.8
Mitelman, F.9
Mandahl, N.10
-
174
-
-
0033980085
-
Putative chromosomal deletions of 9p, 9q and 22q occur preferentially in malignant gastrointestinal stromal tumors
-
(2000)
Int J Cancer
, vol.85
, pp. 633-638
-
-
Kim, N.G.1
Kim, J.J.2
Ahn, J.Y.3
Seong, C.M.4
Noh, S.H.5
Kim, C.B.6
Min, J.S.7
Kim, H.8
-
178
-
-
0035893766
-
Gastrointestinal stromal tumors with KIT mutations exhibit a remarkably homogeneous gene expression profile
-
(2001)
Cancer Res
, vol.61
, pp. 8624-8628
-
-
Allander, S.V.1
Nupponen, N.N.2
Ringnér, M.3
Hostetter, G.4
Maher, G.W.5
Goldberger, N.6
Chen, Y.7
Carpten, J.8
Elkahloun, A.G.9
Meltzer, P.S.10
-
182
-
-
0033634872
-
The metastatic ability of Ewing's sarcoma cells is modulated by stem cell factor and by its receptor c-kit
-
(2000)
Am J Pathol
, vol.157
, pp. 2123-2131
-
-
Landuzzi, L.1
de Giovanni, C.2
Nicoletti, G.3
Rossi, I.4
Ricci, C.5
Astolfi, A.6
Scopece, L.7
Scotlandi, K.8
Serra, M.9
Bagnara, G.P.10
Nanni, P.11
Lollini, P.L.12
-
183
-
-
0032055562
-
c-kit is expressed in soft tissue sarcoma of neuroectodermic origin and its ligand prevents apoptosis of neoplastic cells
-
(1998)
Blood
, vol.91
, pp. 2397-2405
-
-
Ricotti, E.1
Fagioli, F.2
Garelli, E.3
Linari, C.4
Crescenzio, N.5
Horenstein, A.L.6
Pistamiglio, P.7
Vai, S.8
Berger, M.9
di Montezemolo, L.C.10
Madon, E.11
Basso, G.12
-
184
-
-
0036325370
-
New challenges in the identificaiton of gastrointestinal stromal tumors and other possible KIT-driven tumors
-
(2002)
Am J Clin Pathol
, vol.117
, pp. 183-185
-
-
Miettinen, M.1
-
190
-
-
0032981004
-
Expression of c-kit (CS117) and Ki67 provides information about the possible cell of origin and clinical course of gastrointestinal stromal tumours
-
(1999)
Histopathology
, vol.34
, pp. 416-424
-
-
Seidal, T.1
Edvardsson, H.2
-
195
-
-
0034666327
-
Soft tissue leiomyosarcomas and malignant gastrointestinal stromal tumors; differences in clinical outcome and expression of multidrug resistance proteins
-
(2000)
J Clin Oncol
, vol.18
, pp. 3211-3220
-
-
Plaat, B.E.C.1
Hollema, H.2
Molenaar, W.M.3
Torm Broers, G.H.4
Pijpe, J.5
Mastik, M.F.6
Hoekstra, H.J.7
van den Berg, E.8
Scheper, R.J.9
van der Graaf, W.T.A.10
-
200
-
-
0035142836
-
Gastrointestinal stromal tumors-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis
-
(2001)
Virchows Arch
, vol.438
, pp. 1-12
-
-
Miettinen, M.1
Lasota, J.2
-
201
-
-
0035115145
-
Apoptosis, bcl-2 expression, and p53 expression in gastrointestinal stromal/smooth muscle tumors
-
(2001)
Appl Immunohistochem Mol Morphol
, vol.9
, pp. 19-23
-
-
Cunningham, R.E.1
Abbondanzo, S.L.2
Chu, W.S.3
Emory, T.S.4
Sobin, L.H.5
O'Leary, T.J.6
-
203
-
-
0032780384
-
Expression of transforming growth factor-α and epidermal growth factor receptor in gastrointestinal stromal tumours
-
(1999)
Virchows Arch
, vol.435
, pp. 112-115
-
-
Cai, Y.C.1
Jiang, Z.2
Vittimberga, F.3
Xu, X.4
Savas, L.5
Woda, B.6
Callery, M.7
Banner, B.8
-
207
-
-
0035960428
-
Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours; a phase I study
-
(2001)
Lancet
, vol.358
, pp. 1421-1423
-
-
van Oosterom, A.T.1
Judson, I.2
Verweij, J.3
Stroobants, S.4
di Paola, E.D.5
Dimitrijevic, S.6
Martens, M.7
Sciot, R.8
Van Glabbeke, M.9
Silberman, S.10
Nielsen, O.S.11
-
210
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.J.4
Fernandes Reese, S.5
Ford, J.M.6
Capdeville, R.7
Talpaz, M.8
-
211
-
-
0035328851
-
Indolinone tyrosine kinase inhibitors block Kit activation and growth of small cell lung cancer cells
-
(2001)
Cancer Res
, vol.61
, pp. 3660-3668
-
-
Krystal, G.W.1
Honsawek, S.2
Kiewlich, D.3
Liang, C.4
Vasile, S.5
Sun, L.6
McMahon, G.7
Lipson, K.E.8
-
212
-
-
0035899418
-
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein; biological and clinical implications
-
(2001)
Oncogene
, vol.20
, pp. 5054-5058
-
-
Tuveson, D.A.1
Willis, N.A.2
Jacks, T.3
Griffin, J.D.4
Singer, S.5
Fletcher, C.D.M.6
Fletcher, J.A.7
Demetri, G.D.8
-
213
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
Ohno-Jones, S.10
Sawyers, C.L.11
-
214
-
-
0035806490
-
STI571 revolution; can the newer targeted drugs measure up?
-
(2001)
JNCI
, vol.93
, pp. 970-973
-
-
Garber, K.1
-
216
-
-
0031454003
-
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
-
(1997)
Blood
, vol.90
, pp. 4947-4952
-
-
Carroll, M.1
Ohno-Jones, S.2
Tamura, S.3
Buchdunger, E.4
Zimmerman, J.5
Lydon, N.B.6
Gilliland, D.G.7
Druker, B.J.8
-
218
-
-
0034691761
-
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571
-
(2000)
Oncogene
, vol.19
, pp. 3521-3528
-
-
Wang, W.L.1
Healy, M.E.2
Sattler, M.3
Verma, S.4
Lin, J.5
Maulik, G.6
Stiles, C.D.7
Griffin, J.D.8
Johnson, B.E.9
Salgia, R.10
-
223
-
-
0035421175
-
Growth inhibition in dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis
-
(2001)
Cancer Res
, vol.61
, pp. 5778-5783
-
-
Sjöblom, T.1
Shimizu, A.2
O'Brien, K.P.3
Pietras, K.4
Dal Cin, P.5
Buchdunger, E.6
Dumanski, J.P.7
Östman, A.8
Heldin, C.H.9
-
224
-
-
0009416321
-
-
Clarkson BD. Presented at the Molecular Target and Cancer Therapeutics meeting. Miami Beach, FL, USA, January, 2002.
-
-
-
-
235
-
-
0036175997
-
c-kit mutations in gastrointestinal stromal tumors occur preferentially in the spindle rather than in the epithelioid cell variant
-
(2002)
Mod Pathol
, vol.15
, pp. 125-136
-
-
Wardelmann, E.1
Neidt, I.2
Bierhoff, E.3
Speidel, N.4
Manegold, C.5
Fischer, H.P.6
Pfeifer, U.7
Pietsch, T.8
-
236
-
-
0009371753
-
Association of KIT exon 9 mutuations in non-gastric primary site and size, and loack of prognostic impact of KIT exon 11 mutations. A clinicopathologic and molecular study of 84 gastrointestinal stromal tumors (GIST)
-
(2002)
Mod Pathol
, vol.15
-
-
Antonescu, C.R.1
Tschernyavsky, S.J.2
Sommers, G.3
Riedel, E.4
Woodruff, J.M.5
Besmer, P.6
Maki, R.7
Brennan, M.F.8
DeMatteo, R.9
Ladanyi, M.10
-
237
-
-
85058252290
-
A retrospective immunohistochemical analysis of cases diagnosed as intra-abdominal/retroperitoneal 'leiomyosarcoma' (IA/R LMS); the prevalence of potentially treatable KIT-positive extragastrointestinal stromal tumors (EGIST)
-
(2002)
Mod Pathol
, vol.15
-
-
Patel, R.1
Zhang, P.2
Liang, H.H.3
Goldblum, J.R.4
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