Approaching tumour therapy beyond platinum drugs: Status of the art and perspectives of ruthenium drug candidates

Journal of Inorganic Biochemistry

Volumn 106, Issue 1, 2012, Pages 90-99

  Bergamo, A ^a   Gaiddon, C ^b   Schellens, J H M ^c,d   Beijnen, J H ^c,d   Sava, G ^a,e  

^a Callerio Foundation   (Italy)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

^e UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Drug; Mechanism of action; Platinum; Ruthenium; Therapy; Tumour

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; DOXORUBICIN; DW 1; DW 2; GEMCITABINE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IMIDAZOLEDIMETHYLSULFOXIDETETRACHLORORUTHENATE; INDAZOLIUM TETRACHLOROBIS(INDAZOLE)RUTHENATE; ORGANOMETALLIC COMPOUND; OXALIPLATIN; PLATINUM DERIVATIVE; RAPTA T; RDC 11; RM 175; RUTHENIUM DERIVATIVE; STAUROSPORINE; STAUROSPORINE DERIVATIVE; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; BLISTER; BREAST ADENOCARCINOMA; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RESISTANCE; CANCER SURGERY; CELL CYCLE PROGRESSION; COLON CARCINOMA; COLORECTAL CANCER; CYTOTOXICITY; DNA ADDUCT; DNA DAMAGE; DOSE CALCULATION; DRUG HALF LIFE; DRUG POTENTIATION; EXPERIMENTAL NEOPLASM; HUMAN; HUMAN CELL CULTURE; INJECTION SITE PHLEBITIS; LUNG CANCER; LUNG CARCINOMA; LUNG METASTASIS; LUNG NON SMALL CELL CANCER; MALAISE; MELANOMA B16; METASTASIS INHIBITION; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); REVIEW;

EID: 81355161135     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2011.09.030     Document Type: Short Survey

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