Breast cancer resistance protein BCRP (ABCG2)-mediated transepithelial nitrofurantoin secretion and its regulation in human intestinal epithelial (Caco-2) layers

European Journal of Pharmacology

Volumn 672, Issue 1-3, 2011, Pages 70-76

  Wright, Jamie A ^a   Haslam, Iain S ^b   Coleman, Tanya ^b   Simmons, Nicholas L ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

napthoflavone; BCRP; Caco 2 cells; Induction; Intestinal secretion; Nitrofurantoin; Rosiglitazone

Indexed keywords

1,2,3,4,6,7,12,12A OCTAHYDRO 6 ISOBUTYL 9 METHOXY 1,4 DIOXOPYRAZINO[1',2':1,6]PYRIDO[3,4 B]INDOLE 3 PROPANOIC ACID TERT BUTYL ESTER; BETA NAPHTHOFLAVONE; BREAST CANCER RESISTANCE PROTEIN; CHRYSIN; DIBENZOYLMETHANE DERIVATIVE; ESTRADIOL; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; NITROFURANTOIN; PRAZOSIN; QUERCETIN; ROSIGLITAZONE; TERT BUTYLHYDROQUINONE; VERAPAMIL;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENTIATION; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION;

ADENOSINE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; DIET; DOGS; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; HUMANS; INTESTINAL MUCOSA; MICE; NEOPLASM PROTEINS; NITROFURANTOIN; PRAZOSIN; VERAPAMIL;

EID: 81255199239     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.10.004     Document Type: Article

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