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Volumn 38, Issue 4, 2011, Pages 371-389

Genotype-Phenotype Maps Maximizing Evolvability: Modularity Revisited

Author keywords

Conditional evolvability; Constraint; Correlated response; Genetic architecture; Pleiotropy

Indexed keywords


EID: 81255172030     PISSN: 00713260     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11692-011-9136-5     Document Type: Article
Times cited : (41)

References (97)
  • 2
    • 28044443881 scopus 로고    scopus 로고
    • Integration and evolution of the cichlid mandible: The molecular basis of alternate feeding strategies
    • Albertson, R. C., Streelman, J. T., Kocher, T. D., & Yelick, P. C. (2005). Integration and evolution of the cichlid mandible: The molecular basis of alternate feeding strategies. Proceedings of National Academic of Science USA, 102(45), 16287-16292.
    • (2005) Proceedings of National Academic of Science USA , vol.102 , Issue.45 , pp. 16287-16292
    • Albertson, R.C.1    Streelman, J.T.2    Kocher, T.D.3    Yelick, P.C.4
  • 3
    • 42249083243 scopus 로고    scopus 로고
    • Differences in the selection response of serially repeated color pattern characters: Standing variation, development, and evolution
    • Allen, C. E., Beldade, P., Zwaan, B. J., & Brakefield, P. M. (2008). Differences in the selection response of serially repeated color pattern characters: Standing variation, development, and evolution. BMC Evolutionary Biology, 8, 94.
    • (2008) BMC Evolutionary Biology , vol.8 , pp. 94
    • Allen, C.E.1    Beldade, P.2    Zwaan, B.J.3    Brakefield, P.M.4
  • 4
    • 0030947320 scopus 로고    scopus 로고
    • Adaptive inertia caused by hidden pleiotropic effects
    • Baatz, M., & Wagner, G. P. (1997). Adaptive inertia caused by hidden pleiotropic effects. Theoretical Population Biology, 51, 49-66.
    • (1997) Theoretical Population Biology , vol.51 , pp. 49-66
    • Baatz, M.1    Wagner, G.P.2
  • 5
    • 0000096242 scopus 로고
    • The ecological significance of correlation pleiades
    • Berg, R. (1960). The ecological significance of correlation pleiades. Evolution, 17, 171-180.
    • (1960) Evolution , vol.17 , pp. 171-180
    • Berg, R.1
  • 6
    • 13744253159 scopus 로고    scopus 로고
    • Epistasis underlying a fitness trait within a natural population of the pitcher-plant mosquito, Wyeomyia smithii
    • Bradshaw, W. E., Haggerty, B. P., & Holzapfel, C. M. (2005). Epistasis underlying a fitness trait within a natural population of the pitcher-plant mosquito, Wyeomyia smithii. Genetics, 169(1), 485-488.
    • (2005) Genetics , vol.169 , Issue.1 , pp. 485-488
    • Bradshaw, W.E.1    Haggerty, B.P.2    Holzapfel, C.M.3
  • 7
    • 13444306165 scopus 로고    scopus 로고
    • The landscape of genetic complexity across 5, 700 gene expression traits in yeast
    • Brem, R. B., & Kruglyak, L. (2005). The landscape of genetic complexity across 5, 700 gene expression traits in yeast. Proceedings of National Academic of Science USA, 102(5), 1572-1577.
    • (2005) Proceedings of National Academic of Science USA , vol.102 , Issue.5 , pp. 1572-1577
    • Brem, R.B.1    Kruglyak, L.2
  • 8
    • 0037177625 scopus 로고    scopus 로고
    • Genetic dissection of transcriptional regulation in budding yeast
    • Brem, R. B., Yvert, G., Clinton, R., & Kruglyak, L. (2002). Genetic dissection of transcriptional regulation in budding yeast. Science, 296(5568), 752-755.
    • (2002) Science , vol.296 , Issue.5568 , pp. 752-755
    • Brem, R.B.1    Yvert, G.2    Clinton, R.3    Kruglyak, L.4
  • 11
    • 0028188646 scopus 로고
    • Mutation load and mutation-selection-balance in quantitative genetic traits
    • Burger, R., & Hofbauer, J. (1994). Mutation load and mutation-selection-balance in quantitative genetic traits. Journal of Mathematical Biology, 32(3), 193-218.
    • (1994) Journal of Mathematical Biology , vol.32 , Issue.3 , pp. 193-218
    • Burger, R.1    Hofbauer, J.2
  • 12
    • 26244451173 scopus 로고    scopus 로고
    • The role of epistatic gene interactions in the response to selection and the evolution of evolvability
    • Carter, A. J. R., Hermisson, J., & Hansen, T. F. (2005). The role of epistatic gene interactions in the response to selection and the evolution of evolvability. Theoretical Population Biology, 68(3), 179-196.
    • (2005) Theoretical Population Biology , vol.68 , Issue.3 , pp. 179-196
    • Carter, A.J.R.1    Hermisson, J.2    Hansen, T.F.3
  • 13
    • 0025079181 scopus 로고
    • Mutation-selection balance and the evolutionary advantage of sex and recombination
    • Charlesworth, B. (1990). Mutation-selection balance and the evolutionary advantage of sex and recombination. Genetical Research, 55(3), 199-221.
    • (1990) Genetical Research , vol.55 , Issue.3 , pp. 199-221
    • Charlesworth, B.1
  • 14
    • 0021744533 scopus 로고
    • Quantitative genetics and developmental constraints on evolution by selection
    • Cheverud, J. M. (1984). Quantitative genetics and developmental constraints on evolution by selection. Journal of Theoretical Biology, 110(2), 155-171.
    • (1984) Journal of Theoretical Biology , vol.110 , Issue.2 , pp. 155-171
    • Cheverud, J.M.1
  • 15
    • 33746158977 scopus 로고    scopus 로고
    • Developmental integration and the evolution of pleiotropy
    • Cheverud, J. M. (1996). Developmental integration and the evolution of pleiotropy. American Zoologist, 36, 44-50.
    • (1996) American Zoologist , vol.36 , pp. 44-50
    • Cheverud, J.M.1
  • 18
    • 77955842436 scopus 로고    scopus 로고
    • Fisher's model and the genomics of adaptation: Restricted pleiotropy, heterogenous mutation, and parallel evolution
    • Chevin, L. M., Martin, G., & Lenormand, T. (2010). Fisher's model and the genomics of adaptation: Restricted pleiotropy, heterogenous mutation, and parallel evolution. Evolution, 64(11), 3213-3231.
    • (2010) Evolution , vol.64 , Issue.11 , pp. 3213-3231
    • Chevin, L.M.1    Martin, G.2    Lenormand, T.3
  • 20
    • 39749111957 scopus 로고    scopus 로고
    • Evolution of evolvability in a developmental model
    • Draghi, J., & Wagner, G. P. (2008). Evolution of evolvability in a developmental model. Evolution, 62(2), 301-315.
    • (2008) Evolution , vol.62 , Issue.2 , pp. 301-315
    • Draghi, J.1    Wagner, G.P.2
  • 21
    • 79953096336 scopus 로고    scopus 로고
    • The quantitative-genetic and QTL architecture of trait integration and modularity in Brassica rapa across simulated seasonal settings
    • Edwards, C. E., & Weinig, C. (2011). The quantitative-genetic and QTL architecture of trait integration and modularity in Brassica rapa across simulated seasonal settings. Heredity, 106, 661-667.
    • (2011) Heredity , vol.106 , pp. 661-667
    • Edwards, C.E.1    Weinig, C.2
  • 25
    • 79952315134 scopus 로고    scopus 로고
    • Sexual dimorphism increases evolvability in a genetic regulatory network
    • Fierst, J. L. (2011). Sexual dimorphism increases evolvability in a genetic regulatory network. Evolutionary Biology, 38(1), 52-67.
    • (2011) Evolutionary Biology , vol.38 , Issue.1 , pp. 52-67
    • Fierst, J.L.1
  • 27
    • 0028983757 scopus 로고
    • Unpredictability of correlated response to selection: Pleiotropy and sampling interact
    • Gromko, M. H. (1995). Unpredictability of correlated response to selection: Pleiotropy and sampling interact. Evolution, 49(4), 685-693.
    • (1995) Evolution , vol.49 , Issue.4 , pp. 685-693
    • Gromko, M.H.1
  • 28
    • 34249035859 scopus 로고    scopus 로고
    • Evolutionary framework for protein sequence evolution and gene pleiotropy
    • Gu, X. (2007). Evolutionary framework for protein sequence evolution and gene pleiotropy. Genetics, 175(4), 1813-1822.
    • (2007) Genetics , vol.175 , Issue.4 , pp. 1813-1822
    • Gu, X.1
  • 29
    • 0001400708 scopus 로고
    • The effect of variation on fitness
    • Haldane, J. B. S. (1937). The effect of variation on fitness. American Naturalist, 71, 337-349.
    • (1937) American Naturalist , vol.71 , pp. 337-349
    • Haldane, J.B.S.1
  • 31
    • 0037402339 scopus 로고    scopus 로고
    • Is modularity necessary for evolvability? Remarks on the relationship between pleiotropy and evolvability
    • Hansen, T. F. (2003). Is modularity necessary for evolvability? Remarks on the relationship between pleiotropy and evolvability. Biosystems, 69(2-3), 83-94.
    • (2003) Biosystems , vol.69 , Issue.2-3 , pp. 83-94
    • Hansen, T.F.1
  • 33
    • 81255212791 scopus 로고    scopus 로고
    • Epigenetics: Adaptation or contingency?
    • In: B. Hallgrimsson, & B. K. Hall, (Eds.),Berkeley: University of California Press
    • Hansen, T. F. (2011). Epigenetics: Adaptation or contingency? In: B. Hallgrimsson, & B. K. Hall, (Eds.), Epigenetics: Linking genotype and phenotype in development and evolution. Berkeley: University of California Press, pp. 357-376.
    • (2011) Epigenetics: Linking genotype and phenotype in development and evolution , pp. 357-376
    • Hansen, T.F.1
  • 36
    • 49549087249 scopus 로고    scopus 로고
    • Measuring and comparing evolvability and constraint in multivariate characters
    • Hansen, T. F., & Houle, D. (2008). Measuring and comparing evolvability and constraint in multivariate characters. Journal of Evolutionary Biology, 21(5), 1201-1219.
    • (2008) Journal of Evolutionary Biology , vol.21 , Issue.5 , pp. 1201-1219
    • Hansen, T.F.1    Houle, D.2
  • 37
    • 0037594669 scopus 로고    scopus 로고
    • Evolvability and genetic constraint in Dalechampia blossoms: Components of variance and measures of evolvability
    • Hansen, T. F., Pelabon, C., Armbruster, W. S., & Carlson, M. L. (2003b). Evolvability and genetic constraint in Dalechampia blossoms: Components of variance and measures of evolvability. Journal of Evolutionary Biology, 16(4), 754-766.
    • (2003) Journal of Evolutionary Biology , vol.16 , Issue.4 , pp. 754-766
    • Hansen, T.F.1    Pelabon, C.2    Armbruster, W.S.3    Carlson, M.L.4
  • 38
    • 0035198377 scopus 로고    scopus 로고
    • Modeling genetic architecture: A multilinear theory of gene interaction
    • Hansen, T. F., & Wagner, G. P. (2001). Modeling genetic architecture: A multilinear theory of gene interaction. Theoretical Population Biology, 59(1), 61-86.
    • (2001) Theoretical Population Biology , vol.59 , Issue.1 , pp. 61-86
    • Hansen, T.F.1    Wagner, G.P.2
  • 39
    • 7344229253 scopus 로고    scopus 로고
    • Towards a theory of evolutionary adaptation
    • Hartl, D. L., & Taubes, C. H. (1998). Towards a theory of evolutionary adaptation. Genetica, 102(103), 525-533.
    • (1998) Genetica , vol.102 , Issue.103 , pp. 525-533
    • Hartl, D.L.1    Taubes, C.H.2
  • 40
    • 0038104682 scopus 로고    scopus 로고
    • Epistasis in polygenic traits and the evolution of genetic architecture under stabilizing selection
    • Hermisson, J., Hansen, T. F., & Wagner, G. P. (2003). Epistasis in polygenic traits and the evolution of genetic architecture under stabilizing selection. American Naturalist, 161(5), 708-734.
    • (2003) American Naturalist , vol.161 , Issue.5 , pp. 708-734
    • Hermisson, J.1    Hansen, T.F.2    Wagner, G.P.3
  • 41
    • 11244329008 scopus 로고    scopus 로고
    • The population genetic theory of hidden variation and genetic robustness
    • Hermisson, J., & Wagner, G. P. (2004). The population genetic theory of hidden variation and genetic robustness. Genetics, 168, 2271-2284.
    • (2004) Genetics , vol.168 , pp. 2271-2284
    • Hermisson, J.1    Wagner, G.P.2
  • 42
    • 33745354724 scopus 로고    scopus 로고
    • Determining the effective dimensionality of the genetic variance-covariance matrix
    • Hine, E., & Blows, M. W. (2006). Determining the effective dimensionality of the genetic variance-covariance matrix. Genetics, 173(2), 1135-1144.
    • (2006) Genetics , vol.173 , Issue.2 , pp. 1135-1144
    • Hine, E.1    Blows, M.W.2
  • 44
    • 0026016948 scopus 로고
    • Genetic covariance of fitness correlates: What genetic correlations are made of and why it matters
    • Houle, D. (1991). Genetic covariance of fitness correlates: What genetic correlations are made of and why it matters. Evolution, 45(3), 630-648.
    • (1991) Evolution , vol.45 , Issue.3 , pp. 630-648
    • Houle, D.1
  • 45
    • 34047229695 scopus 로고    scopus 로고
    • The mutation matrix and the evolution of evolvability
    • Jones, A. G., Arnold, S. J., & Burger, R. (2007). The mutation matrix and the evolution of evolvability. Evolution, 61(4), 727-745.
    • (2007) Evolution , vol.61 , Issue.4 , pp. 727-745
    • Jones, A.G.1    Arnold, S.J.2    Burger, R.3
  • 46
    • 18944384577 scopus 로고    scopus 로고
    • Quantitative trait loci mapping of floral and leaf morphology traits in Arabidopsis thaliana: Evidence for modular genetic architecture
    • Juenger, T., Perez-Perez, J. M., Bernal, S., & Micol, J. L. (2005). Quantitative trait loci mapping of floral and leaf morphology traits in Arabidopsis thaliana: Evidence for modular genetic architecture. Evolution & Development, 7(3), 259-271.
    • (2005) Evolution & Development , vol.7 , Issue.3 , pp. 259-271
    • Juenger, T.1    Perez-perez, J.M.2    Bernal, S.3    Micol, J.L.4
  • 48
    • 65649116390 scopus 로고    scopus 로고
    • Patterns of quantitative genetic variation in multiple dimensions
    • Kirkpatrick, M. (2009). Patterns of quantitative genetic variation in multiple dimensions. Genetica, 136(2), 271-284.
    • (2009) Genetica , vol.136 , Issue.2 , pp. 271-284
    • Kirkpatrick, M.1
  • 49
    • 2442588743 scopus 로고    scopus 로고
    • Integration and modularity of quantitative trait locus effects on geometric shape in the mouse mandible
    • Klingenberg, C. P., Leamy, L. J., & Cheverud, J. M. (2004). Integration and modularity of quantitative trait locus effects on geometric shape in the mouse mandible. Genetics, 166(4), 1909-1921.
    • (2004) Genetics , vol.166 , Issue.4 , pp. 1909-1921
    • Klingenberg, C.P.1    Leamy, L.J.2    Cheverud, J.M.3
  • 50
    • 0001288442 scopus 로고
    • Quantitative genetic analysis of multivariate evolution, applied to brain: Body size allometry
    • Lande, R. (1979). Quantitative genetic analysis of multivariate evolution, applied to brain: Body size allometry. Evolution, 33, 402-416.
    • (1979) Evolution , vol.33 , pp. 402-416
    • Lande, R.1
  • 51
    • 0018946312 scopus 로고
    • The genetic covariance between characters maintained by pleiotropic mutations
    • Lande, R. (1980). The genetic covariance between characters maintained by pleiotropic mutations. Genetics, 94(1), 203-215.
    • (1980) Genetics , vol.94 , Issue.1 , pp. 203-215
    • Lande, R.1
  • 52
    • 52049106813 scopus 로고    scopus 로고
    • Dissection of the genetic architecture of body weight in chicken reveals the impact of epistasis on domestication traits
    • Le Rouzic, A., Alvarez-Castro, J. M., & Carlborg, O. (2008). Dissection of the genetic architecture of body weight in chicken reveals the impact of epistasis on domestication traits. Genetics, 179(3), 1591-1599.
    • (2008) Genetics , vol.179 , Issue.3 , pp. 1591-1599
    • Le Rouzic, A.1    Alvarez-Castro, J.M.2    Carlborg, O.3
  • 53
  • 54
    • 34548724489 scopus 로고    scopus 로고
    • The evolution of genetic networks by non-adaptive processes
    • Lynch, M. (2007a). The evolution of genetic networks by non-adaptive processes. Nature Reviews. Genetics, 8(10), 803-813.
    • (2007) Nature Reviews. Genetics , vol.8 , Issue.10 , pp. 803-813
    • Lynch, M.1
  • 55
    • 34547396004 scopus 로고    scopus 로고
    • The frailty of adaptive hypotheses for the origins of organismal complexity
    • Lynch, M. (2007b). The frailty of adaptive hypotheses for the origins of organismal complexity. Proceedings of National Academic of Science USA, 104(Suppl 1), 8597-8604.
    • (2007) Proceedings of National Academic of Science USA , vol.104 , Issue.SUPPL.1 , pp. 8597-8604
    • Lynch, M.1
  • 57
    • 29244435707 scopus 로고    scopus 로고
    • Epistasis for fitness-related quantitative traits in Arabidopsis thaliana grown in the field and in the greenhouse
    • Malmberg, R. L., Held, S., Waits, A., & Mauricio, R. (2005). Epistasis for fitness-related quantitative traits in Arabidopsis thaliana grown in the field and in the greenhouse. Genetics, 171(4), 2013-2027.
    • (2005) Genetics , vol.171 , Issue.4 , pp. 2013-2027
    • Malmberg, R.L.1    Held, S.2    Waits, A.3    Mauricio, R.4
  • 58
    • 33747080569 scopus 로고    scopus 로고
    • A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species
    • Martin, G., & Lenormand, T. (2006). A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species. Evolution, 60(5), 893-907.
    • (2006) Evolution , vol.60 , Issue.5 , pp. 893-907
    • Martin, G.1    Lenormand, T.2
  • 59
    • 34047218357 scopus 로고    scopus 로고
    • The phenotypic and genetic covariance structure of drosophilid wings
    • McGuigan, K., & Blows, M. W. (2007). The phenotypic and genetic covariance structure of drosophilid wings. Evolution, 61(4), 902-911.
    • (2007) Evolution , vol.61 , Issue.4 , pp. 902-911
    • McGuigan, K.1    Blows, M.W.2
  • 60
    • 0033832152 scopus 로고    scopus 로고
    • Is the genotype-phenotype map modular? A statistical approach using mouse quantitative trait loci data
    • Mezey, J. G., Cheverud, J. M., & Wagner, G. P. (2000). Is the genotype-phenotype map modular? A statistical approach using mouse quantitative trait loci data. Genetics, 156(1), 305-311.
    • (2000) Genetics , vol.156 , Issue.1 , pp. 305-311
    • Mezey, J.G.1    Cheverud, J.M.2    Wagner, G.P.3
  • 61
    • 19544380541 scopus 로고    scopus 로고
    • The dimensionality of genetic variation for wing shape in Drosophila melanogaster
    • Mezey, J. G., & Houle, D. (2005). The dimensionality of genetic variation for wing shape in Drosophila melanogaster. Evolution, 59(5), 1027-1038.
    • (2005) Evolution , vol.59 , Issue.5 , pp. 1027-1038
    • Mezey, J.G.1    Houle, D.2
  • 62
    • 72249083317 scopus 로고    scopus 로고
    • The developmental basis of variational modularity: Insights from quantitative genetics, morphometrics, and developmental biology
    • Mitteroecker, P. (2009). The developmental basis of variational modularity: Insights from quantitative genetics, morphometrics, and developmental biology. Evolutionary Biology, 36(4), 377-385.
    • (2009) Evolutionary Biology , vol.36 , Issue.4 , pp. 377-385
    • Mitteroecker, P.1
  • 65
    • 0034025692 scopus 로고    scopus 로고
    • Adaptation and the cost of complexity
    • Orr, A. H. (2000). Adaptation and the cost of complexity. Evolution, 54(1), 13-20.
    • (2000) Evolution , vol.54 , Issue.1 , pp. 13-20
    • Orr, A.H.1
  • 66
    • 0027095368 scopus 로고
    • The genetics of adaptation: A reassessment
    • Orr, H. A., & Coyne, J. A. (1992). The genetics of adaptation: A reassessment. American Naturalist, 140(5), 725-742.
    • (1992) American Naturalist , vol.140 , Issue.5 , pp. 725-742
    • Orr, H.A.1    Coyne, J.A.2
  • 67
    • 79955748576 scopus 로고    scopus 로고
    • Evolution of adaptive phenotypic variation patterns by direct selection for evolvability
    • Pavlicev, M., Cheverud, J. M., & Wagner, G. P. (2011a). Evolution of adaptive phenotypic variation patterns by direct selection for evolvability. Proceedings of Biological Sciences, 278(1713), 1903-1912.
    • (2011) Proceedings of Biological Sciences , vol.278 , Issue.1713 , pp. 1903-1912
    • Pavlicev, M.1    Cheverud, J.M.2    Wagner, G.P.3
  • 68
    • 37749014093 scopus 로고    scopus 로고
    • Genetic variation in pleiotropy: Differential epistasis as a source of variation in the allometric relationship between long bone lengths and body weight
    • Pavlicev, M., Kenney-Hunt, J. P., Norgard, E. A., Roseman, C. C., Wolf, J. B., & Cheverud, J. M. (2008). Genetic variation in pleiotropy: Differential epistasis as a source of variation in the allometric relationship between long bone lengths and body weight. Evolution, 62(1), 199-213.
    • (2008) Evolution , vol.62 , Issue.1 , pp. 199-213
    • Pavlicev, M.1    Kenney-Hunt, J.P.2    Norgard, E.A.3    Roseman, C.C.4    Wolf, J.B.5    Cheverud, J.M.6
  • 69
    • 78751608419 scopus 로고    scopus 로고
    • Directionality of epistasis in a murine intercross population
    • Pavlicev, M., Le Rouzic, A., Cheverud, J. M., Wagner, G. P., & Hansen, T. F. (2010). Directionality of epistasis in a murine intercross population. Genetics, 185, 1489-1505.
    • (2010) Genetics , vol.185 , pp. 1489-1505
    • Pavlicev, M.1    Le Rouzic, A.2    Cheverud, J.M.3    Wagner, G.P.4    Hansen, T.F.5
  • 71
    • 13944272337 scopus 로고    scopus 로고
    • The opportunity for canalization and the evolution of genetic networks
    • Proulx, S. R., & Phillips, P. C. (2005). The opportunity for canalization and the evolution of genetic networks. American Naturalist, 165(2), 147-162.
    • (2005) American Naturalist , vol.165 , Issue.2 , pp. 147-162
    • Proulx, S.R.1    Phillips, P.C.2
  • 73
    • 76349120849 scopus 로고    scopus 로고
    • Phenotypic integration without modularity: Testing hypotheses about the distribution of pleiotropic quantitative trait loci in a continuous space
    • Roseman, C., Kenney-Hunt, J. P., & Cheverud, J. M. (2009). Phenotypic integration without modularity: Testing hypotheses about the distribution of pleiotropic quantitative trait loci in a continuous space. Evolutionary Biology, 36(3), 282-291.
    • (2009) Evolutionary Biology , vol.36 , Issue.3 , pp. 282-291
    • Roseman, C.1    Kenney-Hunt, J.P.2    Cheverud, J.M.3
  • 74
    • 33644907774 scopus 로고    scopus 로고
    • The effect of multifunctionality on the rate of evolution in yeast
    • Salathe, M., Ackermann, M., & Bonhoeffer, S. (2006). The effect of multifunctionality on the rate of evolution in yeast. Molecular Biology and Evolution, 23(4), 721-722.
    • (2006) Molecular Biology and Evolution , vol.23 , Issue.4 , pp. 721-722
    • Salathe, M.1    Ackermann, M.2    Bonhoeffer, S.3
  • 76
    • 0021419667 scopus 로고
    • Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle
    • Turelli, M. (1984). Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle. Theoretical Population Biology, 25(2), 138-193.
    • (1984) Theoretical Population Biology , vol.25 , Issue.2 , pp. 138-193
    • Turelli, M.1
  • 77
    • 0022233074 scopus 로고
    • Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits
    • Turelli, M. (1985). Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits. Genetics, 111(1), 165-195.
    • (1985) Genetics , vol.111 , Issue.1 , pp. 165-195
    • Turelli, M.1
  • 78
    • 84993924998 scopus 로고
    • The influence of variation and of developmental constraints on the rate of multivariate phenotypic evolution
    • Wagner, G. P. (1988). The influence of variation and of developmental constraints on the rate of multivariate phenotypic evolution. Journal of Evolutionary Biology, 1(1), 45-66.
    • (1988) Journal of Evolutionary Biology , vol.1 , Issue.1 , pp. 45-66
    • Wagner, G.P.1
  • 79
    • 0024523744 scopus 로고
    • Multivariate mutation-selection balance with constrained pleiotropic effects
    • Wagner, G. P. (1989). Multivariate mutation-selection balance with constrained pleiotropic effects. Genetics, 122(1), 223-234.
    • (1989) Genetics , vol.122 , Issue.1 , pp. 223-234
    • Wagner, G.P.1
  • 80
    • 4243773720 scopus 로고    scopus 로고
    • Homologues, natural kinds and the evolution of modularity
    • Wagner, G. P. (Ed.). (1996). Homologues, natural kinds and the evolution of modularity. American Zoologist, 36, 36-43.
    • (1996) American Zoologist , vol.36 , pp. 36-43
    • Wagner, G.P.1
  • 82
    • 0029661332 scopus 로고    scopus 로고
    • Complex adaptations and evolution of evolvability
    • Wagner, G. P., & Altenberg, L. (1996). Complex adaptations and evolution of evolvability. Evolution, 50, 967-976.
    • (1996) Evolution , vol.50 , pp. 967-976
    • Wagner, G.P.1    Altenberg, L.2
  • 86
    • 79951799418 scopus 로고    scopus 로고
    • The pleiotropic structure of the genotype-phenotype map: The evolvability of complex organisms
    • Wagner, G. P., & Zhang, J. (2011). The pleiotropic structure of the genotype-phenotype map: The evolvability of complex organisms. Nature Reviews. Genetics, 12(3), 204-213.
    • (2011) Nature Reviews. Genetics , vol.12 , Issue.3 , pp. 204-213
    • Wagner, G.P.1    Zhang, J.2
  • 87
    • 76249110585 scopus 로고    scopus 로고
    • Abundant genetic variation + strong selection = multivariate genetic constraints: A geometric view of adaptation
    • Walsh, B., & Blows, M. (2009). Abundant genetic variation + strong selection = multivariate genetic constraints: A geometric view of adaptation. Annual Review of Ecology, Evolution, and Systematics, 40, 41-59.
    • (2009) Annual Review of Ecology, Evolution, and Systematics , vol.40 , pp. 41-59
    • Walsh, B.1    Blows, M.2
  • 88
    • 78149257568 scopus 로고    scopus 로고
    • Genomic patterns of pleiotropy and the evolution of complexity
    • Wang, Z., Liao, B. Y., & Zhang, J. (2010). Genomic patterns of pleiotropy and the evolution of complexity. Proceedings of National Academic of Science USA, 107(42), 18034-18039.
    • (2010) Proceedings of National Academic of Science USA , vol.107 , Issue.42 , pp. 18034-18039
    • Wang, Z.1    Liao, B.Y.2    Zhang, J.3
  • 89
    • 0141768269 scopus 로고    scopus 로고
    • Non-equivalent loci and mutation-selection balance
    • Waxman, D., & Welch, J. (2003). Non-equivalent loci and mutation-selection balance. Theoretical Population Biology, 63(4), 339-345.
    • (2003) Theoretical Population Biology , vol.63 , Issue.4 , pp. 339-345
    • Waxman, D.1    Welch, J.2
  • 90
    • 26644472934 scopus 로고    scopus 로고
    • Fisher's microscope and Haldane's ellipse
    • Waxman, D., & Welch, J. J. (2005). Fisher's microscope and Haldane's ellipse. American Naturalist, 166(4), 447-457.
    • (2005) American Naturalist , vol.166 , Issue.4 , pp. 447-457
    • Waxman, D.1    Welch, J.J.2
  • 91
    • 0035989436 scopus 로고    scopus 로고
    • Nonequivalent Loci and the distribution of mutant effects
    • Welch, J. J., & Waxman, D. (2002). Nonequivalent Loci and the distribution of mutant effects. Genetics, 161(2), 897-904.
    • (2002) Genetics , vol.161 , Issue.2 , pp. 897-904
    • Welch, J.J.1    Waxman, D.2
  • 92
    • 0043286749 scopus 로고    scopus 로고
    • Modularity and the cost of complexity
    • Welch, J. J., & Waxman, D. (2003). Modularity and the cost of complexity. Evolution, 57(8), 1723-1734.
    • (2003) Evolution , vol.57 , Issue.8 , pp. 1723-1734
    • Welch, J.J.1    Waxman, D.2
  • 93
    • 34249055193 scopus 로고    scopus 로고
    • Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in Arabidopsis
    • West, M. A., Kim, K., Kliebenstein, D. J., van Leeuwen, H., Michelmore, R. W., Doerge, R. W., et al. (2007). Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in Arabidopsis. Genetics, 175(3), 1441-1450.
    • (2007) Genetics , vol.175 , Issue.3 , pp. 1441-1450
    • West, M.A.1    Kim, K.2    Kliebenstein, D.J.3    van Leeuwen, H.4    Michelmore, R.W.5    Doerge, R.W.6    St Clair, D.A.7
  • 95
    • 33747619846 scopus 로고    scopus 로고
    • The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice
    • Wolf, J. B., Pomp, D., Eisen, E. J., Cheverud, J. M., & Leamy, L. J. (2006). The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice. Evolution & Development, 8(5), 468-476.
    • (2006) Evolution & Development , vol.8 , Issue.5 , pp. 468-476
    • Wolf, J.B.1    Pomp, D.2    Eisen, E.J.3    Cheverud, J.M.4    Leamy, L.J.5
  • 96
    • 77954140531 scopus 로고    scopus 로고
    • Common SNPs explain a large proportion of the heritability for human height
    • Yang, J., Benyamin, B., McEvoy, B. P., Gordon, S., Henders, A. K., Nyholt, D. R., et al. (2010). Common SNPs explain a large proportion of the heritability for human height. Nature Genetics, 42(7), 565-569.
    • (2010) Nature Genetics , vol.42 , Issue.7 , pp. 565-569
    • Yang, J.1    Benyamin, B.2    McEvoy, B.P.3    Gordon, S.4    Henders, A.K.5    Nyholt, D.R.6


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