Neuroprotective effects of purslane herb aquenous extracts against d-galactose induced neurotoxicity

Chemico-Biological Interactions

Volumn 170, Issue 3, 2007, Pages 145-152

  Hongxing, Zhang ^a   Nancai, Yu ^a   Guofu, Huang ^a   Jianbo, Shao ^c   Yanxia, Wu ^a   Hanju, Huang ^b   Qian, Liu ^a   Wei, Ma ^a   Yandong, Yi ^a   Hao, Huang ^a,b  

^a First Hospital of Wuhan   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c Tujia Nationality Autonomous County   (China)

Author keywords

p21waf1; p53; Purslane herb aquenous extracts; Telomere lengths

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; GALACTOSE; MALONALDEHYDE; MESSENGER RNA; PLANT EXTRACT; PROTEIN P53; PURSLANE HERB AQUENOUS EXTRACT; SUPEROXIDE DISMUTASE; TELOMERASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; DRUG DETERMINATION; DRUG MECHANISM; DRUG SYNTHESIS; ENVIRONMENT; ENZYME ACTIVITY; GENE EXPRESSION; LEARNING; MALE; MEMORY; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OPEN FIELD BEHAVIOR; REAL TIME POLYMERASE CHAIN REACTION; RODENT; TELOMERE; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BEHAVIOR, ANIMAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GALACTOSE; MALE; MALONDIALDEHYDE; MICE; NEURONS; NEUROPROTECTIVE AGENTS; PLANT EXTRACTS; PORTULACA; SUPEROXIDE DISMUTASE; TUMOR SUPPRESSOR PROTEIN P53;

MUS; PORTULACACEAE;

EID: 36049045459     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2007.07.009     Document Type: Article

References (23)

1. Cai G. Progress on chemical compositions and pharmacological function of Portulace oleracea L. J. Anhui Agric. Sci. 33 (2005) 1090-2090
2. Honggui Z., Jingmin Z., Tianbin Z., et al. Chemical constituents from Portulaca oleracea L. J. Chinese Pharm. Sci. 13 (2004) 291-292
3. Xiyun I S., Ning L., Bo C., et al. The study on antioxidation property of flavonoids from Portulaca Oleracea L. J. Shenyang Agric. Univ. 37 (2006) 108-110
4. Nancai Y., Hao H., Qian L., et al. Effect of water extract of purslane herb on physical functions, morphology of hepatic cells and brain neurons in senile mouse. Chinese Hosp. Pharm. J. 26 (2006) 1510-1512
5. Guangcai N., Dan Z., Yingzi J., et al. Study on the anti-aging efect of polysaccharide from Portulaca oleracea L. on mice. Anti-senility Chinese Agric. Sci. Bull. 22 (2006) 35-37
6. Hao L., Lihua L., Meizhi C., et al. Effect of purslane in delaying aging. Chinese Clin. Rehab. J. 9 (2005) 170-171
7. Zhang X., Li W.B., and Zhang B.L. Biochemical changes in d-galactose induced subacute toxicity and mimetic aging in mice. Chinese J. Pharmacol. Toxicol. 4 (1990) 309-310
8. Wei H.F., Li L., Song Q.J., Ai H.X., Chu J., and Li W. Behavioural study of the d-galactose induced aging model in C57BL/6J mice. Behav. Brain Res. 157 (2005) 245-251
9. d'Adda di Fagagna F., Reaper P.M., Clay-Farrace L., et al. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426 (2003) 194-198
10. Porath I.B., and Weinberg R.A. When cells get stressed: an integrative view of cellular senescence. J. Clin. Invest. 113 (2004) 8-13
11. von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem. Sci. 27 (2002) 339-344
12. Von Zglinicki T. Telomeres and replicative senescence: is it only length that counts?. Cancer Lett. 168 (2001) 111-116
13. Kilani S., Abdelwahed A., Chraief I.R., et al. Chemical composition, antibacterial and antimutagenic activities of essential oil from (Tunisian) Cyperus rotundus. J. Essent Oil Res. 17 (2005) 695-700
14. Tona L., Kambu K., Ngimbi N., et al. Antiamoebic and phytochemical screening of some Congolese medicinal plants. J. Ethnopharmacol. 61 (1998) 57-65
15. McCord J.M., and Fridowich I. An enzymic function for erythrocuprein. J. Biol. Chem. 244 (1969) 6049-6055
16. Uchiyama M., and Mihara M. Determination of malondialdehyde precursor in tissues by thiobarbituric acid test. Anal. Biochem. 86 (1978) 271-278
17. Xiang L., Xing a D., Wang W., et al. Alkaloids from Portulaca oleracea L. Phytochemistry 66 (2005) 2595-2601
18. Rogina B., and Helfand S.L. Cu,Zn superoxide dismutase defiency accelerates the time course of an age-related marker in Drosophila melanogaster. Biogerontology 1 2 (2000) 163-169
19. Martin-Ruiz C., Saretzki G., Petrie J., et al. Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span. J. Biol. Chem. 23 (2004) 17826-17833
20. Harley C.B., Futcher A.B., and Greider C.W. Telomeres shorten during ageing of human fibroblasts. Nature 345 (1990) 458-460
21. Herbig U., Jobling W.A., Chen B.P., et al. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol. Cell. 14 (2004) 501-513
22. Brown J.P., Wei W., and Sedivy J.M. Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. Science 277 (1997) 831-834
23. Parker S.B., Eichele G., Zhang P., et al. Elledge, p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 267 (1995) 1024-1027