Electrospun conducting polymer nanofibers and electrical stimulation of nerve stem cells

Journal of Bioscience and Bioengineering

Volumn 112, Issue 5, 2011, Pages 501-507

  Prabhakaran, Molamma P ^a   Ghasemi Mobarakeh, Laleh ^b   Jin, Guorui ^a   Ramakrishna, Seeram ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Conducting polymer; Nerve tissue engineering; Neurite elongation; Poly l lactide; Polyaniline

Indexed keywords

ELECTRICAL STIMULATIONS; ELECTROSPUN NANOFIBERS; ELECTROSPUNS; FIBER DIAMETERS; IN-VITRO; NERVE GRAFTS; NERVE REGENERATION; NERVE TISSUE; NERVE TISSUE ENGINEERING; NEURITE OUTGROWTH; NEURITES; PLLA; POLY-L-LACTIDE; POLYMERIC SCAFFOLD; PROBE MEASUREMENTS; SYNERGISTIC COMBINATIONS; TWO-POINT;

BIOMECHANICS; CONDUCTING POLYMERS; ELECTRIC FIELDS; ELECTRICAL ENGINEERING; ELECTRON SPECTROSCOPY; MECHANICAL PROPERTIES; NANOFIBERS; POLYANILINE; SCANNING ELECTRON MICROSCOPY; STEM CELLS; TISSUE;

SCAFFOLDS (BIOLOGY);

NANOFIBER; POLYANILINE; POLYLACTIC ACID; POLYMER;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL PROLIFERATION; CELL STRUCTURE; CONDUCTANCE; CONTROLLED STUDY; ELECTRIC FIELD; ELECTROSPINNING; ELECTROSTIMULATION; IN VITRO STUDY; MEASUREMENT; NANOFABRICATION; NERVE CELL STIMULATION; NERVE FIBER GROWTH; NEURAL STEM CELL; NONHUMAN; PHYSICAL CHEMISTRY; RAT; SCANNING ELECTRON MICROSCOPY; TENSILE STRENGTH; TISSUE REGENERATION; X RAY PHOTOELECTRON SPECTROSCOPY;

ANILINE COMPOUNDS; ELECTRIC STIMULATION; ELECTROCHEMISTRY; LACTIC ACID; NANOFIBERS; NERVE REGENERATION; NEURAL STEM CELLS; NEURITES; POLYESTERS; SURFACE PROPERTIES; TISSUE ENGINEERING;

EID: 81255158011     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2011.07.010     Document Type: Article

References (45)

1. Schmidt C.E., Leach J.B. Neural tissue engineering: strategies for repair and regeneration. Ann. Rev. Biomed. Eng. 2003, 5:293-347.
2. Zhang N., Yan H., Wen X. Tissue-engineering approaches for axonal guidance. Brain Res. Rev. 2005, 49:48-64.
3. Ray T.H., Swift L.A., Jang J.H., Shea L.D. Patterned PLG substrate for localized DNA delivery and directed neurite extension. Biomaterials 2007, 28:2603-2611.
4. Bunge M.B. Bridging areas of injury in the spinal cord. Neuroscientist 2001, 7:325-339.
5. Bregman B.S., Coumans J.V., Dai H.N., Kuhn P.L., Lynskey J., McAtee M., Sandhu F. Transplants and neurotrophic factors increase regeneration and recovery of function after spinal cord injury. Prog. Brain Res. 2002, 137:257-273.
6. Higuchi A., Shirano K., Harashima M., Yoon B.O., Hara M., Hattori M., Imamura K. Chemically modified polysulfone hollow fibers with vinylpyrrolidone having improved blood compatibility. Biomaterials 2002, 23:2659-2666.
7. Wang H.J., Lin Z.X., Liu X.M., Sheng S.Y., Wang J.Y. Heparin loaded zein microsphere film and hemocompatibility. J. Control. Rel. 2005, 105:120-131.
8. Jakubiec B., Marois Y., Zhang Z., Roy R., Sigot-Luizard M.F., Dugre F.J., King M.W., Dao L.H., Laroche G., Guidoin R. In vitro cellular response to polypyrrole-coated woven polyester fabrics: potential benefits of electrical conductivity. J. Biomed. Mat. Res. 1998, 41:519-526.
9. Kotwal A., Schmidt C.E. Electrical stimulation alters protein adsorption and nerve cell interactions with electrically conducting biomaterials. Biomaterials 2001, 22:1055-1064.
10. Cai J., Peng X., Nelson K.D., Eberhart R., Smith G.M. Permeable guidance channels containing microfilament scaffolds enhance axon growth and maturation. J. Biomed. Mater. Res. 2005, 75A:374-386.
11. Widmer M.S., Gupta P.K., Lu L., Meszlenyi R.K., Evans G.R.D., Brandt K., Savel T., Gukrlek A., Patrick C.W., Mikos A.G. Manufacture of porous biodegradable polymer conduits by an extrusion process for guided tissue regeneration. Biomaterials 1998, 19:1945-1955.
12. Rangappa N., Romero A., Nelson K.D., Eberhart R.C., Smith G.M. Laminin-coated poly(L-lactide) filaments induce robust neurite growth while providing directional orientation. J. Biomed. Mater. Res. 2000, 51:625-634.
13. Bai X., Li X., Li N., Zuo Y., Wang L., Li J., Qiu S. Synthesis of cluster polyaniline nanorod via a binary oxidant system. Mater. Sci. Eng. C 2007, 27:695-699.
14. Li M.Y., Guo Y., Wei Y., MacDiarmid A.G., Lelkes P.I. Electrospinning polyaniline contained gelatin nanofibers for tissue engineering applications. Biomaterials 2006, 27:2705-2715.
15. Hopkins A.R., Rasmussen P.G. Characterization of solution and solid state properties of undoped and doped polyanilines processed from hexafluoro-2-propanol. Macromolecules 1996, 29:7838-7846.
16. Ghasemi-Mobarakeh L., Prabhakaran M.P., Morshed M., Esfahani M.H.N., Ramakrishna S. Electrical stimulation of nerve cells using conductive nanofibrous scaffolds for nerve tissue engineering. Tissue Eng. 2009, 15:3605-3619.
17. Yuan X., Mak A.F.T., Yao K. Comparative observation of accelerated degradation of poly(l-lactic acid) fibres in phosphate buffered saline and a dilute alkaline solution. Polym. Degrad. Stab. 2002, 75:45-53.
18. You Y., Lee S.W., Youk J.H., Min B.M., Lee S.J., Park W.H. In vitro degradation behavior of non-porous ultra-fine poly(glycolic acid)/poly(L-lactic acid) fibres and porous ultra-fine poly(glycolic acid) fibres. Polym. Degrad. Stab. 2005, 90:441-448.
19. Schmidt C.E., Shastri V.R., Vacanti J.P., Langer R. Stimulation of neurite outgrowth using an electrically conducting polymer. Proc. Natl. Acad. Sci. USA 1997, 94:8948-8953.
20. Ma P.X. Biomimetic materials for tissue engineering. Adv. Drug Deliv. Rev. 2008, 60:184-198.
21. Shin H., Jo S., Mikos A.G. Biomimetic materials for tissue engineering. Biomaterials 2003, 24:4353-4364.
22. Rivers T.J., Hudson T.W., Schmidt C.E. Synthesis of a novel, biodegradable electrically conducting polymer for biomedical applications. Adv. Funct. Mater. 2002, 12:33-37.
23. Hutcheon G.A., Messiou C., Wyre R.M., Davies M.C., Downes S. Water absorption and surface properties of novel poly(ethylmethacrylate) polymer systems for use in bone and cartilage repair. Biomaterials 2001, 22:667-676.
24. Qin X.H., Yang E.L.L., Wang N., Yuan S. Effect of different salts on electrospinning of polyacrylonitrile polymer solution. J. Appl. Polym. Sci. 2007, 103:3865-3870.
25. Bhattarai S.R., Bhattarai N., Yi H.K., Hwang P.H., Cha D.I., Kim H.Y. Novel biodegradable electrospun membrane: scaffold for tissue engineering. Biomaterials 2004, 25:2595-2602.
26. Elias K.L., Price R.L., Webster T.J. Enhanced functions of osteoblasts on nanometer diameter carbon fibers. Biomaterials 2002, 23:3279-3287.
27. Cai K., Yao K., Cui Y., Yang Z., Li X., Xie H., Qing T., Gao L. Influence of different surface modification treatments on poly(D, L-lactic acid) with silk fibroin and their effects on the culture of osteoblast in vitro. Biomaterials 2002, 23:1603-1611.
28. Jeong S.I., Jun I.D., Choi M.J., Nho Y.C., Lee Y.M., Shin H. Development of electroactive and elastic nanofibers that contain polyaniline and poly(L-lactide-co-caprolactone) for the control of cell adhesion. Macromol. Biosci. 2008, 8:627-637.
29. Zeng X.R., Ko T.M. Structure-conductivity relationships of iodine doped polyaniline. J. Polym. Sci. B Polym. Phys. 1997, 35:1993-2001.
30. Saravanana S., Mathaia C.J., Anantharamana M.R., Venkatachalamb S., Prabhakaran P.V. Investigations on the electrical and structural properties of polyaniline doped with camphor sulphonic acid. J. Phys. Chem. Solids 2006, 67:1496-1501.
31. Kim Y.T., Haftel V.K., Kumar S., Bellamkonda R.V. The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps. Biomaterials 2008, 29:3117-3127.
32. Borschel G.H., Kia K.F., Kuzon W.M., Dennis R.G. Mechanical properties of acellular peripheral nerve. J. Surg. Res. 2003, 114:133-139.
33. Avlyanov J.K., Min Y.G., Macdiarmid A.G., Epstein A.J. Polyaniline conformational changes induced in solution by variation of solvent and doping level. Synth. Met. 1995, 72:65-71.
34. Wang H.J., Ji L.W., Li D.F., Wang J.Y. Characterization of nanostructure and cellcompatibility of polyaniline films with different dopant acids. J. Phys. Chem. B 2008, 112:2671-2677.
35. He L., Liao S., Quan D., Ma K., Chan C., Ramakrishna S., Lu J. Synergistic effects of electrospun PLLA fiber dimension and pattern on neonatal mouse cerebellum C17.2 stem cells. Acta Biomater. 2010, 6:2960-2969.
36. Chen M., Patra P.K., Warner S.B., Bhowmick S. Role of fiber diameter in adhesion and proliferation of NIH 3T3 fibroblasts on electrospun polycaprolactone scaffolds. Tissue Eng. 2007, 13:579-587.
37. Schense J.C., Hubbell J.A. Three dimensional migration of neuritis is mediated by adhesion site density and affinity. J. Biol. Chem. 2000, 275:6813-6818.
38. Gunn J.W., Turner S.D., Mann B.K. Adhesive and mechanical properties of hydrogels influence neurite extension. J. Biomed. Mater. Res. 2005, 72A:91-97.
39. Xie J., Willerth S.M., Li X., Macewan M.R., Rader A., Sakiyama-Elbert S.E., Xia Y. The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages. Biomaterials 2009, 30:354-362.
40. Li J.M., Shi R.Y. Fabrication of patterned multi-walled poly-L-lactic acid conduits for nerve regeneration. J. Neurosci. Methods 2007, 165:257-264.
41. Xie J., MacEwan M.R., Willerth S.M., Li X., Moran D.W., Sakiyama-Elbert S.E., Xia Y. Conductive core-sheath nanofibers and their potential application in neural tissue engineering. Adv. Fun. Mater. 2009, 14:2312-2318.
42. Pedrotty D.M., Koh J., Davis B.H., Taylor D.A., Wolf P., Niklason L.E. Engineering skeletal myoblasts: roles of three-dimensional culture and electrical stimulation. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H1620-H1626.
43. Supronowicz P.R., Ajayan P.M., Ullmann K.R., Arulanandam B.P., Metzger D.W., Bizios R. Novel current-conducting composite substrates for exposing osteoblasts to alternating current stimulation. J. Biomed. Mater. Res. 2001, 59:499-506.
44. Patel N., Poo M.M. Orientation of neurite growth by extracellular electric fields. J. Neurosci. 1982, 2:483-496.
45. Jun I., Jeong S., Shin H. The stimulation of myoblast differentiation by electrically conductive sub-micron fibers. Biomaterials 2009, 30:2038-2047.