Patterned PLG substrates for localized DNA delivery and directed neurite extension

Biomaterials

Volumn 28, Issue 16, 2007, Pages 2603-2611

  Houchin Ray, Tiffany ^a   Swift, Laura A ^a   Jang, Jae Hyung ^c   Shea, Lonnie D ^a,b  

^a Northwestern University   (United States)

^b Department of Institute for BioNanotechnology in Medicine ^*  (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gene delivery; Nerve guidance; Nerve regeneration; PLG; Substrate mediated delivery

Indexed keywords

CELL IMMOBILIZATION; CELLS; DNA; NEUROLOGY; TUMORS;

GENE DELIVERY; NERVE GUIDANCE; NERVE REGENERATION; POLYLACTIDE-CO-GLYCOLIDE (PLG); SUBSTRATE MEDIATED DELIVERY;

TISSUE ENGINEERING;

DNA; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; POLYGLACTIN;

ACCESSORY CELL; ARTICLE; CELL CULTURE; CELL SURVIVAL; EMBRYO; GENE TARGETING; HUMAN; HUMAN CELL; NERVE CELL; NERVE FIBER GROWTH; NERVE TRACT; NEURITE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANIMALS; CELL LINE; CHICK EMBRYO; COATED MATERIALS, BIOCOMPATIBLE; COCULTURE TECHNIQUES; DNA; FLUORESCENT DYES; GENE TRANSFER TECHNIQUES; HUMANS; MATERIALS TESTING; MICE; NERVE GROWTH FACTOR; NEURITES; POLYGLACTIN 910; SURFACE PROPERTIES; TISSUE ENGINEERING;

EID: 33847681043     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2007.01.042     Document Type: Article

References (31)

1. Yiu G., and He Z. Glial inhibition of CNS axon regeneration. Nat Rev Neurosci 7 8 (2006) 617-627
2. David S., and Lacroix S. Molecular approaches to spinal cord repair. Annu Rev Neurosci 26 (2003) 411-440
3. Geller H.M., and Fawcett J.W. Building a bridge: engineering spinal cord repair. Exp Neurol 174 2 (2002) 125-136
4. Schmidt C.E., and Leach J.B. Neural tissue engineering: strategies for repair and regeneration. Annu Rev Biomed Eng 5 (2003) 293-347
5. Zhang N., Yan H., and Wen X. Tissue-engineering approaches for axonal guidance. Brain Res Rev 49 1 (2005) 48-64
6. Yang Y., De Laporte L., Rives C.B., Jang J.H., Lin W.C., Shull K.R., et al. Neurotrophin releasing single and multiple lumen nerve conduits. J Control Release 104 3 (2005) 433-446
7. Moore M.J., Friedman J.A., Lewellyn E.B., Mantila S.M., Krych A.J., Ameenuddin S., et al. Multiple-channel scaffolds to promote spinal cord axon regeneration. Biomaterials 27 3 (2006) 419-429
8. Mahoney M.J., Chen R.R., Tan J., and Saltzman W.M. The influence of microchannels on neurite growth and architecture. Biomaterials 26 7 (2005) 771-778
9. Friedman J.A., Windebank A.J., Moore M.J., Spinner R.J., Currier B.L., and Yaszemski M.J. Biodegradable polymer grafts for surgical repair of the injured spinal cord. Neurosurgery 51 3 (2002) 742-751 discussion 51-2
10. Bunge M.B. Bridging areas of injury in the spinal cord. Neuroscientist 7 4 (2001) 325-339
11. Bregman B.S., Coumans J.V., Dai H.N., Kuhn P.L., Lynskey J., McAtee M., et al. Transplants and neurotrophic factors increase regeneration and recovery of function after spinal cord injury. Prog Brain Res 137 (2002) 257-273
12. Boyd J.G., and Gordon T. Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury. Mol Neurobiol 27 3 (2003) 277-324
13. Whittlesey K.J., and Shea L.D. Delivery systems for small molecule drugs, proteins, and DNA: the neuroscience/biomaterial interface. Exp Neurol 190 1 (2004) 1-16
14. Jang J.H., Rives C.B., and Shea L.D. Plasmid delivery in vivo from porous tissue-engineering scaffolds: transgene expression and cellular transfection. Mol Ther 12 3 (2005) 475-483
15. Segura T., Volk M.J., and Shea L.D. Substrate-mediated DNA delivery: role of the cationic polymer structure and extent of modification. J Control Release 93 1 (2003) 69-84
16. Bengali Z., Pannier A.K., Segura T., Anderson B.C., Jang J.H., Mustoe T.A., et al. Gene delivery through cell culture substrate adsorbed DNA complexes. Biotechnol Bioeng 90 3 (2005) 290-302
17. Segura T., and Shea L.D. Surface-tethered DNA complexes for enhanced gene delivery. Bioconjugate Chem 13 3 (2002) 621-629
18. Jang J.H., Bengali Z., Houchin T.L., and Shea L.D. Surface adsorption of DNA to tissue engineering scaffolds for efficient gene delivery. J Biomed Mater Res Part A 77A 1 (2006) 50-58
19. Whittlesey K.J., and Shea L.D. Nerve growth factor expression by PLG-mediated lipofection. Biomaterials 27 11 (2006) 2477-2486
20. Meijering E., Jacob M., Sarria J.C.F., Steiner P., Hirling H., and Unser M. Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images. Cytometry Part A 58A 2 (2004) 167-176
21. Lee H., Jeong J.H., and Park T.G. PEG grafted polylysine with fusogenic peptide for gene delivery: high transfection efficiency with low cytotoxicity. J Control Release 79 1-3 (2002) 283-291
22. Koyama Y., Ito T., Matsumoto H., Tanioka A., Okuda T., Yamaura N., et al. Novel poly(ethylene glycol) derivatives with carboxylic acid pendant groups: synthesis and their protection and enhancing effect on non-viral gene transfection systems. J Biomater Sci Polym Ed 14 6 (2003) 515-531
23. Kalil K., Szebenyi G., and Dent E.W. Common mechanisms underlying growth cone guidance and axon branching. J Neurobiol 44 2 (2000) 145-158
24. Goldner J.S., Bruder J.M., Li G., Gazzola D., and Hoffman-Kim D. Neurite bridging across micropatterned grooves. Biomaterials 27 3 (2006) 460-472
25. Kam L., Shain W., Turner J.N., and Bizios R. Axonal outgrowth of hippocampal neurons on micro-scale networks of polylysine-conjugated laminin. Biomaterials 22 10 (2001) 1049-1054
26. Miller C., Jeftinija S., and Mallapragada S. Synergistic effects of physical and chemical guidance cues on neurite alignment and outgrowth on biodegradable polymer substrates. Tissue Eng 8 3 (2002) 367-378
27. Heller D.A., Garga V., Kelleher K.J., Lee T.C., Mahbubani S., Sigworth L.A., et al. Patterned networks of mouse hippocampal neurons on peptide-coated gold surfaces. Biomaterials 26 8 (2005) 883-889
28. Anderson M.J., and Waxman S.G. Regeneration of spinal neurons in inframammalian vertebrates: morphological and developmental aspects. J Hirnforsch 24 4 (1983) 371-398
29. Jones L.L., Oudega M., Bunge M.B., and Tuszynski M.H. Neurotrophic factors, cellular bridges and gene therapy for spinal cord injury. J Physiol 533 Part 1 (2001) 83-89
30. Ramer M.S., Priestley J.V., and McMahon S.B. Functional regeneration of sensory axons into the adult spinal cord. Nature 403 6767 (2000) 312-316
31. Zhou L., and Shine H.D. Neurotrophic factors expressed in both cortex and spinal cord induce axonal plasticity after spinal cord injury. J Neurosci Res 74 2 (2003) 221-226