6,6-Spiroimine analogs of (-)-gymnodimine A: Synthesis and biological evaluation on nicotinic acetylcholine receptors

Organic and Biomolecular Chemistry

Volumn 9, Issue 23, 2011, Pages 8112-8118

  Duroure, Leslie ^a   Jousseaume, Thierry ^a   Aráoz, Rómulo ^a   Barré, Elvina ^a   Retailleau, Pascal ^a   Chabaud, Laurent ^a   Molgó, Jordi ^a   Guillou, Catherine ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC ALLYLIC ALKYLATIONS; BIOLOGICAL ACTIVITIES; BIOLOGICAL EVALUATION; ENANTIOSELECTIVE; KETOESTER; MICHAEL ADDITIONS; NICOTINIC ACETYLCHOLINE RECEPTORS; NICOTINIC ACETYLCHOLINE RECEPTORS (NACHRS); OPTICALLY ACTIVE FORM; PHARMACOPHORES; QUATERNARY CARBON; XENOPUS OOCYTE;

ALDEHYDES;

ADDITION REACTIONS;

FUSED HETEROCYCLIC RINGS; GYMNODIMINE A; IMINE; LIGAND; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; SPIRO COMPOUND;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; DRUG EFFECT; ELECTROPHYSIOLOGY; FEMALE; GENETICS; HUMAN; METABOLISM; STEREOISOMERISM; SYNTHESIS; XENOPUS LAEVIS;

ANIMALS; ELECTROPHYSIOLOGICAL PHENOMENA; FEMALE; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; IMINES; LIGANDS; MOLECULAR STRUCTURE; NICOTINIC ANTAGONISTS; RECEPTORS, NICOTINIC; SPIRO COMPOUNDS; STEREOISOMERISM; XENOPUS LAEVIS;

EID: 81255138090     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c1ob06257c     Document Type: Article

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