Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli

Journal of Biological Chemistry

Volumn 286, Issue 46, 2011, Pages 40219-40231

  Santangelo, Maria De La Paz ^a,g   Gest, Petra M ^a   Guerin, Marcelo E ^b,c   Coinçon, Mathieu ^d   Pham, Ha ^a   Ryan, Gavin ^a   Puckett, Susan E ^e   Spencer, John S ^a   Gonzalez Juarrero, Mercedes ^a   Daher, Racha ^f   Lenaerts, Anne J ^a   Schnappinger, Dirk ^e   Therisod, Michel ^f   Ehrt, Sabine ^e   Sygusch, Jurgen ^d   Jackson, Mary ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^c BASQUE FOUNDATION FOR SCIENCE   (Spain)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f UNIVERSITÉ PARIS SUD   (France)

^g INSTITUTO NACIONAL DE TECNOLOGÍA AGROPECUARIA   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ALDOLASES; ANTI-PLASMIN; BINDING ACTIVITIES; CELL SURFACES; CLASS II; ENZYMATIC ACTIVITIES; FRUCTOSE 1 ,6-BISPHOSPHATE; GLUCONEOGENESIS; GLUCOSE-CONTAINING MEDIUM; GROWTH CONDITIONS; GUINEA PIGS; HYDROXAMATE; IN-VIVO; KEY ENZYMES; KNOCK OUTS; M. TUBERCULOSIS; MAMMALIAN CELLS; MYCOBACTERIUM TUBERCULOSIS; NATIVE FORMS; NATURAL SUBSTRATES; OXYGEN DEPLETION; REACTION MECHANISM; SURFACE LABELING; THERAPEUTIC TARGETS; ZINC IONS;

BACILLI; CELL MEMBRANES; ENZYMES; FRUCTOSE; GENES; GLUCOSE; MAMMALS;

SUBSTRATES;

ALPHA 2 ANTIPLASMIN; FRUCTOSE 1,6 BISPHOSPHATE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE; HYDROXAMIC ACID; OXYGEN; PLASMIN; PLASMINOGEN; ZINC ION;

ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL GROWTH; CELL SURFACE; CELL TRANSPORT; CRYSTAL STRUCTURE; CULTURE MEDIUM; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE; ENZYME SYNTHESIS; FBA TB GENE; GENE LOCUS; GLUCONEOGENESIS; GLYCOLYSIS; GUINEA PIG; HOST PATHOGEN INTERACTION; IN VIVO STUDY; MAMMAL CELL; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

ALPHA-2-ANTIPLASMIN; ANIMALS; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; FIBRINOLYSIN; FRUCTOSE-BISPHOSPHATE ALDOLASE; FRUCTOSEDIPHOSPHATES; GENE KNOCKDOWN TECHNIQUES; GLUCONEOGENESIS; GUINEA PIGS; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; TUBERCULOSIS, PULMONARY;

BACILLI (CLASS); CAVIA; MAMMALIA; MUS; MYCOBACTERIUM TUBERCULOSIS;

EID: 81255124096     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.259440     Document Type: Article

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