Restraint of Fgf8 signaling by retinoic acid signaling is required for proper heart and forelimb formation

Developmental Biology

Volumn 358, Issue 1, 2011, Pages 44-55

  Sorrell, Mollie R Johnson ^a   Waxman, Joshua S ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Fgf signaling; Forelimb; Heart; Retinoic acid; Zebrafish

Indexed keywords

FIBROBLAST GROWTH FACTOR 8; RETINOIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL COUNT; EMBRYO; FORELIMB; GASTRULATION; HEART DEVELOPMENT; HEART MUSCLE CELL; LIMB DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STEM CELL; ZEBRA FISH;

DANIO RERIO;

EID: 81155159733     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2011.07.022     Document Type: Article

References (45)

1. Ahn D.G., Kourakis M.J., Rohde L.A., Silver L.M., Ho R.K. T-box gene tbx5 is essential for formation of the pectoral limb bud. Nature 2002, 417:754-758.
2. Alsan B.H., Schultheiss T.M. Regulation of avian cardiogenesis by Fgf8 signaling. Development 2002, 129:1935-1943.
3. Barron M., Gao M., Lough J. Requirement for BMP and FGF signaling during cardiogenic induction in non-precardiac mesoderm is specific, transient, and cooperative. Dev. Dyn. 2000, 218:383-393.
4. Bruneau B.G., Nemer G., Schmitt J.P., Charron F., Robitaille L., Caron S., Conner D.A., Gessler M., Nemer M., Seidman C.E., Seidman J.G. A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell 2001, 106:709-721.
5. Connors S.A., Tucker J.A., Mullins M.C. Temporal and spatial action of tolloid (mini fin) and chordin to pattern tail tissues. Dev. Biol. 2006, 293:191-202.
6. Draper B.W., Morcos P.A., Kimmel C.B. Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Genesis 2001, 30:154-156.
7. Feng L., Hernandez R.E., Waxman J.S., Yelon D., Moens C.B. Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism. Dev. Biol. 2010, 338:1-14.
8. Garrity D.M., Childs S., Fishman M.C. The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome. Development 2002, 129:4635-4645.
9. Grandel H., Brand M. Zebrafish limb development is triggered by a retinoic acid signal during gastrulation. Dev. Dyn. 2010.
10. Grandel H., Lun K., Rauch G.J., Rhinn M., Piotrowski T., Houart C., Sordino P., Kuchler A.M., Schulte-Merker S., Geisler R., Holder N., Wilson S.W., Brand M. Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development 2002, 129:2851-2865.
11. Hall C., Flores M.V., Murison G., Crosier K., Crosier P. An essential role for zebrafish Fgfrl1 during gill cartilage development. Mech. Dev. 2006, 123:925-940.
12. Heine U.I., Roberts A.B., Munoz E.F., Roche N.S., Sporn M.B. Effects of retinoid deficiency on the development of the heart and vascular system of the quail embryo. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 1985, 50:135-152.
13. Hernandez R.E., Rikhof H.A., Bachmann R., Moens C.B. vhnf1 integrates global RA patterning and local FGF signals to direct posterior hindbrain development in zebrafish. Development 2004, 131:4511-4520.
14. Keegan B.R., Feldman J.L., Begemann G., Ingham P.W., Yelon D. Retinoic acid signaling restricts the cardiac progenitor pool. Science 2005, 307:247-249.
15. Lohnes D., Mark M., Mendelsohn C., Dolle P., Dierich A., Gorry P., Gansmuller A., Chambon P. Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants. Development 1994, 120:2723-2748.
16. Londin E.R., Mentzer L., Gates K.P., Sirotkin H.I. Expression and regulation of the zinc finger transcription factor Churchill during zebrafish development. Gene Expr. Patterns 2007, 7:645-650.
17. Mably J.D., Mohideen M.A., Burns C.G., Chen J.N., Fishman M.C. heart of glass regulates the concentric growth of the heart in zebrafish. Curr. Biol. 2003, 13:2138-2147.
18. Marques S.R., Lee Y., Poss K.D., Yelon D. Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart. Dev. Biol. 2008, 321:397-406.
19. Maves L., Kimmel C.B. Dynamic and sequential patterning of the zebrafish posterior hindbrain by retinoic acid. Dev. Biol. 2005, 285:593-605.
20. Mendelsohn C., Lohnes D., Decimo D., Lufkin T., LeMeur M., Chambon P., Mark M. Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 1994, 120:2749-2771.
21. Mohammadi M., McMahon G., Sun L., Tang C., Hirth P., Yeh B.K., Hubbard S.R., Schlessinger J. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 1997, 276:955-960.
22. Nechiporuk A., Linbo T., Poss K.D., Raible D.W. Specification of epibranchial placodes in zebrafish. Development 2007, 134:611-623.
23. Niederreither K., Subbarayan V., Dolle P., Chambon P. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat. Genet. 1999, 21:444-448.
24. Niederreither K., Vermot J., Messaddeq N., Schuhbaur B., Chambon P., Dolle P. Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse. Development 2001, 128:1019-1031.
25. Niederreither K., Vermot J., Schuhbaur B., Chambon P., Dolle P. Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse. Development 2002, 129:3563-3574.
26. Peterkin T., Gibson A., Patient R. Common genetic control of haemangioblast and cardiac development in zebrafish. Development 2009, 136:1465-1474.
27. Pownall M.E., Welm B.E., Freeman K.W., Spencer D.M., Rosen J.M., Isaacs H.V. An inducible system for the study of FGF signalling in early amphibian development. Dev. Biol. (NY 1985) 2003, 256:89-99.
28. Reifers F., Bohli H., Walsh E.C., Crossley P.H., Stainier D.Y., Brand M. Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 1998, 125:2381-2395.
29. Reifers F., Walsh E.C., Leger S., Stainier D.Y., Brand M. Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar). Development 2000, 127:225-235.
30. Russo J.E., Hauguitz D., Hilton J. Inhibition of mouse cytosolic aldehyde dehydrogenase by 4-(diethylamino)benzaldehyde. Biochem. Pharmacol. 1988, 37:1639-1642.
31. Ryckebusch L., Wang Z., Bertrand N., Lin S.C., Chi X., Schwartz R., Zaffran S., Niederreither K. Retinoic acid deficiency alters second heart field formation. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:2913-2918.
32. Schoenebeck J.J., Keegan B.R., Yelon D. Vessel and blood specification override cardiac potential in anterior mesoderm. Dev. Cell 2007, 13:254-267.
33. Sirbu I.O., Zhao X., Duester G. Retinoic acid controls heart anteroposterior patterning by down-regulating Isl1 through the Fgf8 pathway. Dev. Dyn. 2008, 237:1627-1635.
34. Sumanas S., Gomez G., Zhao Y., Park C., Choi K., Lin S. Interplay among Etsrp/ER71, Scl, and Alk8 signaling controls endothelial and myeloid cell formation. Blood 2008, 111:4500-4510.
35. Sumanas S., Lin S. Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol. 2006, 4:e10.
36. Trueb B., Neuhauss S.C., Baertschi S., Rieckmann T., Schild C., Taeschler S. Fish possess multiple copies of fgfrl1, the gene for a novel FGF receptor. Biochim. Biophys. Acta 2005, 1727:65-74.
37. Warga R.M., Kane D.A., Ho R.K. Fate mapping embryonic blood in zebrafish: multi- and unipotential lineages are segregated at gastrulation. Dev. Cell 2009, 16:744-755.
38. Waxman J.S., Keegan B.R., Roberts R.W., Poss K.D., Yelon D. Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish. Dev. Cell 2008, 15:923-934.
39. Waxman J.S., Yelon D. Increased Hox activity mimics the teratogenic effects of excess retinoic acid signaling. Dev. Dyn. 2009, 238:1207-1213.
40. Westerfield M. The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (Danio rerio) 1995, University of Oregon Press. 3 ed.
41. Wilson G.N. Correlated heart/limb anomalies in Mendelian syndromes provide evidence for a cardiomelic developmental field. Am. J. Med. Genet. 1998, 76:297-305.
42. Yelon D., Horne S.A., Stainier D.Y. Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish. Dev. Biol. 1999, 214:23-37.
43. Yelon D., Ticho B., Halpern M.E., Ruvinsky I., Ho R.K., Silver L.M., Stainier D.Y. The bHLH transcription factor hand2 plays parallel roles in zebrafish heart and pectoral fin development. Development 2000, 127:2573-2582.
44. Zhao X., Sirbu I.O., Mic F.A., Molotkova N., Molotkov A., Kumar S., Duester G. Retinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterning. Curr. Biol. 2009, 19:1050-1057.
45. Znosko W.A., Yu S., Thomas K., Molina G.A., Li C., Tsang W., Dawid I.B., Moon A.M., Tsang M. Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development. Dev. Biol. 2010, 342:11-25.