Old friends form alliance against podocytes

Kidney International

Volumn 80, Issue 11, 2011, Pages 1117-1119

  Simons, Matias ^a,b   Huber, Tobias B ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; DICKKOPF 1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; NEPHRIN; NOTCH RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN; WNT1 PROTEIN;

ALBUMINURIA; APOPTOSIS; CELL ADHESION; CELL DAMAGE; CELL DEATH; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CELL SEPARATION; CELL STRESS; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; DISEASE COURSE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; FOCAL GLOMERULOSCLEROSIS; GLOMERULOPATHY; GLOMERULOSCLEROSIS; GLOMERULUS BASEMENT MEMBRANE; IN VIVO STUDY; KIDNEY FAILURE; KIDNEY POLYCYSTIC DISEASE; KIDNEY STRUCTURE; KIDNEY TUBULE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; TREATMENT PLANNING; UPREGULATION;

EID: 81155132148     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.298     Document Type: Note

References (11)

1. Nishita M, Hashimoto MK, Ogata S et al. Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer. Nature 2000; 403: 781-785. (Pubitemid 30111840)
2. Wang D, Dai C, Li Y et al. Canonical Wnt/β-catenin signaling mediates transforming growth factor-β1-driven podocyte injury and proteinuria. Kidney Int 2011; 80: 1159-1169.
3. Schiffer M, Bitzer M, Roberts ISD et al. Apoptosis in podocytes induced by TGF-beta and Smad7. J Clin Invest 2001; 108: 807-816. (Pubitemid 32880291)
4. Niranjan T, Bielesz B, Gruenwald A et al. The Notch pathway in podocytes plays a role in the development of glomerular disease. Nat Med 2008; 14: 290-298. (Pubitemid 351347919)
5. Dai C, Stolz DB, Kiss LP et al. Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria. J Am Soc Nephrol 2009; 20: 1997-2008.
6. Kato H, Gruenwald A, Suh JH et al. Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival. J Biol Chem 2011; 286: 26003-26015.
7. He W, Kang YS, Dai C, Liu Y. Blockade of Wnt/beta-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury. J Am Soc Nephrol 2011; 22: 90-103.
8. G ö del M, Hartleben B, Herbach N et al. Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest 2011; 121: 2197-2209.
9. Inoki K, Mori H, Wang J et al. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J Clin Invest 2011; 121: 2181-2196.
10. Simons M, Walz G. Polycystic kidney disease: cell division without a c(l)ue? Kidney Int 2006; 70: 854-864. (Pubitemid 44285962)
11. Lasagni L, Ballerini L, Angelotti ML et al. Notch activation differentially regulates renal progenitors proliferation and differentiation toward the podocyte lineage in glomerular disorders. Stem Cells 2010; 28: 1674-1685.