메뉴 건너뛰기




Volumn 28, Issue 9, 2010, Pages 1674-1685

Notch activation differentially regulates renal progenitors proliferation and differentiation toward the podocyte lineage in glomerular disorders

Author keywords

Glomerulonephritis; Glomerulosclerosis; Kidney; Renal progenitors; Renal stem cells

Indexed keywords

NOTCH RECEPTOR; DIPEPTIDE; DOXORUBICIN; N (N (3,5 DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT BUTYL ESTER; N-(N-(3,5-DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT-BUTYL ESTER;

EID: 77957857754     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.492     Document Type: Article
Times cited : (148)

References (53)
  • 1
    • 4344652866 scopus 로고    scopus 로고
    • Projecting the United States ESRD population: Issues regarding treatment of patients with ESRD
    • Szczech LA, Lazar IL. Projecting the United States ESRD population: Issues regarding treatment of patients with ESRD. Kidney Int Suppl 2004;90:S3-S7.
    • (2004) Kidney Int Suppl , vol.90
    • Szczech, L.A.1    Lazar, I.L.2
  • 2
    • 33645733358 scopus 로고    scopus 로고
    • Pathogenesis of nonimmune glomerulopathies
    • Kwoh C, Shannon MB, Miner JH et al. Pathogenesis of nonimmune glomerulopathies. Annu Rev Pathol 2006;1:349-374.
    • (2006) Annu Rev Pathol , vol.1 , pp. 349-374
    • Kwoh, C.1    Shannon, M.B.2    Miner, J.H.3
  • 3
    • 34250006557 scopus 로고    scopus 로고
    • The spectrum of podocytopathies: A unifying view of glomerular diseases
    • Wiggins RC. The spectrum of podocytopathies: A unifying view of glomerular diseases. Kidney Int 2007;71:1205-1214.
    • (2007) Kidney Int , vol.71 , pp. 1205-1214
    • Wiggins, R.C.1
  • 4
    • 0033452520 scopus 로고    scopus 로고
    • The role of the podocyte in glomerulosclerosis
    • Kriz W, Lemley KV. The role of the podocyte in glomerulosclerosis. Curr Opin Nephrol Hypertens 1999;8:489-497.
    • (1999) Curr Opin Nephrol Hypertens , vol.8 , pp. 489-497
    • Kriz, W.1    Lemley, K.V.2
  • 5
    • 0036891810 scopus 로고    scopus 로고
    • Podocyte biology and response to injury
    • Mundel P, Shankland SJ. Podocyte biology and response to injury. J Am Soc Nephrol 2002;13:3005-3015.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 3005-3015
    • Mundel, P.1    Shankland, S.J.2
  • 6
    • 33748051419 scopus 로고    scopus 로고
    • Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys
    • Sagrinati C, Netti GS, Mazzinghi B et al. Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. J Am Soc Nephrol 2006;17:2443-2456.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2443-2456
    • Sagrinati, C.1    Netti, G.S.2    Mazzinghi, B.3
  • 7
    • 36849090211 scopus 로고    scopus 로고
    • Regenerative potential of embryonic renal multipotent progenitors in acute renal failure
    • Lazzeri E, Crescioli C, Ronconi E et al. Regenerative potential of embryonic renal multipotent progenitors in acute renal failure. J Am Soc Nephrol 2007;18:3128-3138.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 3128-3138
    • Lazzeri, E.1    Crescioli, C.2    Ronconi, E.3
  • 8
    • 39549122204 scopus 로고    scopus 로고
    • Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells
    • Mazzinghi B, Ronconi E, Lazzeri E et al. Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells. J Exp Med 2008;205:479-490.
    • (2008) J Exp Med , vol.205 , pp. 479-490
    • Mazzinghi, B.1    Ronconi, E.2    Lazzeri, E.3
  • 9
    • 46049113052 scopus 로고    scopus 로고
    • Stem-cell approaches for kidney repair: Choosing the right cells
    • Sagrinati C, Ronconi E, Lazzeri E et al. Stem-cell approaches for kidney repair: Choosing the right cells. Trends Mol Med 2008;14:277-285.
    • (2008) Trends Mol Med , vol.14 , pp. 277-285
    • Sagrinati, C.1    Ronconi, E.2    Lazzeri, E.3
  • 10
    • 59949101434 scopus 로고    scopus 로고
    • Regeneration of glomerular podocytes by human renal progenitors
    • Ronconi E, Sagrinati C, Angelotti ML et al. Regeneration of glomerular podocytes by human renal progenitors. J Am Soc Nephrol 2009;20:322-332.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 322-332
    • Ronconi, E.1    Sagrinati, C.2    Angelotti, M.L.3
  • 11
    • 59949092665 scopus 로고    scopus 로고
    • Recruitment of podocytes from glomerular parietal epithelial cells
    • Appel D, Kershaw D, Smeets B et al. Recruitment of podocytes from glomerular parietal epithelial cells. J Am Soc Nephrol 2009;20:333-343.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 333-343
    • Appel, D.1    Kershaw, D.2    Smeets, B.3
  • 12
    • 70349868343 scopus 로고    scopus 로고
    • Toward the identification of a "renopoietic system"?
    • Romagnani P. Toward the identification of a "renopoietic system"? Stem Cells 2009;27:2247-2253.
    • (2009) Stem Cells , vol.27 , pp. 2247-2253
    • Romagnani, P.1
  • 13
    • 72049121911 scopus 로고    scopus 로고
    • Renal progenitor cells contribute to hyperplastic glomerular lesions of different types of podocytopathies and in crescentic glomerulonephritis
    • Smeets B, Angelotti ML, Rizzo P et al. Renal progenitor cells contribute to hyperplastic glomerular lesions of different types of podocytopathies and in crescentic glomerulonephritis. J Am Soc Nephrol 2009;20:2593-603.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 2593-2603
    • Smeets, B.1    Angelotti, M.L.2    Rizzo, P.3
  • 14
    • 72049129967 scopus 로고    scopus 로고
    • Parietal epithelial cells are the main component of glomerular extracapillary cellular lesions
    • Smeets B, Uhlig S, Fuss A et al. Parietal epithelial cells are the main component of glomerular extracapillary cellular lesions. J Am Soc Nephrol 2009;20:2604-2615.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 2604-2615
    • Smeets, B.1    Uhlig, S.2    Fuss, A.3
  • 16
    • 77952561383 scopus 로고    scopus 로고
    • Glomerular epithelial stem cells: The good, the bad and the ugly
    • (in press)
    • Lasagni L, Romagnani P. Glomerular epithelial stem cells: The good, the bad and the ugly. J Am Soc Nephrol 2010 (in press).
    • (2010) J Am Soc Nephrol
    • Lasagni, L.1    Romagnani, P.2
  • 17
    • 77952563922 scopus 로고    scopus 로고
    • From Proteus to Prometheus: Learning from fish to modulate regeneration
    • Romagnani P. From Proteus to Prometheus: Learning from fish to modulate regeneration. J Am Soc Nephrol 2010;21:726-728.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 726-728
    • Romagnani, P.1
  • 18
    • 33846705750 scopus 로고    scopus 로고
    • Epithelial Stem Cells: Turning over New Leaves
    • DOI 10.1016/j.cell.2007.01.014, PII S0092867407000700
    • Blanpain C, Horsley V, Fuchs E. Epithelial stem cells: Turning over new leaves. Cell 2007;128:445-458. (Pubitemid 46198895)
    • (2007) Cell , vol.128 , Issue.3 , pp. 445-458
    • Blanpain, C.1    Horsley, V.2    Fuchs, E.3
  • 19
    • 65549121943 scopus 로고    scopus 로고
    • Notch signalling: The core pathway and its posttranslational regulation
    • Fortini ME. Notch signalling: The core pathway and its posttranslational regulation. Dev Cell 2009;16:633-647.
    • (2009) Dev Cell , vol.16 , pp. 633-647
    • Fortini, M.E.1
  • 20
    • 34548825987 scopus 로고    scopus 로고
    • Differential Notch signalling distinguishes neural stem cells from intermediate progenitors
    • Mizutani K, Yoon K, Dang L et al. Differential Notch signalling distinguishes neural stem cells from intermediate progenitors. Nature 2007;449:351-355.
    • (2007) Nature , vol.449 , pp. 351-355
    • Mizutani, K.1    Yoon, K.2    Dang, L.3
  • 21
    • 47949097215 scopus 로고    scopus 로고
    • Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
    • Carlson ME, Hsu M, Conboy IM. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature 2008;454:528-532.
    • (2008) Nature , vol.454 , pp. 528-532
    • Carlson, M.E.1    Hsu, M.2    Conboy, I.M.3
  • 22
    • 53749089803 scopus 로고    scopus 로고
    • Notch activates cell cycle reentry and progression in quiescent cardiomyocytes
    • Campa VM, Gutiérrez-Lanza R, Cerignoli F et al. Notch activates cell cycle reentry and progression in quiescent cardiomyocytes. J Cell Biol 2008;183:129-141.
    • (2008) J Cell Biol , vol.183 , pp. 129-141
    • Campa, V.M.1    Gutiérrez-Lanza, R.2    Cerignoli, F.3
  • 23
    • 0035173672 scopus 로고    scopus 로고
    • Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity
    • Romagnani P, Annunziato F, Lasagni L et al. Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity. J Clin Invest 2001;107:53-63.
    • (2001) J Clin Invest , vol.107 , pp. 53-63
    • Romagnani, P.1    Annunziato, F.2    Lasagni, L.3
  • 24
    • 12444260282 scopus 로고    scopus 로고
    • An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4
    • Lasagni L, Francalanci M, Annunziato F et al. An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. J Exp Med 2003;197:1537-1549.
    • (2003) J Exp Med , vol.197 , pp. 1537-1549
    • Lasagni, L.1    Francalanci, M.2    Annunziato, F.3
  • 26
    • 70349569241 scopus 로고    scopus 로고
    • Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells
    • Woo SM, Kim J, Han HW et al. Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells. BMC Neurosci 2009;10:97-108.
    • (2009) BMC Neurosci , vol.10 , pp. 97-108
    • Woo, S.M.1    Kim, J.2    Han, H.W.3
  • 27
    • 41949087056 scopus 로고    scopus 로고
    • Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus
    • Varnum-Finney B, Dallas MH, Kato K et al. Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus. Blood 2008;111:2615-2620.
    • (2008) Blood , vol.111 , pp. 2615-2620
    • Varnum-Finney, B.1    Dallas, M.H.2    Kato, K.3
  • 29
    • 12344256754 scopus 로고    scopus 로고
    • Pathways to nephron loss starting from glomerular diseases-insights from animal models
    • Kriz W, LeHir M. Pathways to nephron loss starting from glomerular diseases-insights from animal models. Kidney Int 2005;67:404-419.
    • (2005) Kidney Int , vol.67 , pp. 404-419
    • Kriz, W.1    LeHir, M.2
  • 30
    • 33750003969 scopus 로고    scopus 로고
    • Adriamycin nephropathy in severe combined immunodeficient (SCID) mice
    • Lee VW, Wang Y, Qin X et al. Adriamycin nephropathy in severe combined immunodeficient (SCID) mice. Nephrol Dial Transplant 2006;21:3293-3298.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 3293-3298
    • Lee, V.W.1    Wang, Y.2    Qin, X.3
  • 31
    • 8544282400 scopus 로고    scopus 로고
    • Cyclin kinase inhibitors are increased during experimental membranous nephropathy: Potential role in limiting glomerular epithelial cell proliferation in vivo
    • Shankland SJ, Floege J, Thomas SE et al. Cyclin kinase inhibitors are increased during experimental membranous nephropathy: Potential role in limiting glomerular epithelial cell proliferation in vivo. Kidney Int 1997;52:404-413.
    • (1997) Kidney Int , vol.52 , pp. 404-413
    • Shankland, S.J.1    Floege, J.2    Thomas, S.E.3
  • 33
    • 0036841123 scopus 로고    scopus 로고
    • Inhibitory Smads and TGF-β signalling in glomerular cells
    • Schiffer M, Schiffer LE, Gupta A et al. Inhibitory Smads and TGF-β signalling in glomerular cells. J Am Soc Nephrol 2002;13:2657-2666.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2657-2666
    • Schiffer, M.1    Schiffer, L.E.2    Gupta, A.3
  • 34
    • 57649149333 scopus 로고    scopus 로고
    • Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009
    • Kroemer G, Galluzzi L, Vandenabeele P et al. Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 2009;16:3-11.
    • (2009) Cell Death Differ , vol.16 , pp. 3-11
    • Kroemer, G.1    Galluzzi, L.2    Vandenabeele, P.3
  • 36
    • 0028875577 scopus 로고
    • Long-term treatment of rats with FGF-2 results in focal segmental glomerulosclerosis
    • Kriz W, Hähnel B, Rösener S et al. Long-term treatment of rats with FGF-2 results in focal segmental glomerulosclerosis. Kidney Int 1995;48:1435-1450.
    • (1995) Kidney Int , vol.48 , pp. 1435-1450
    • Kriz, W.1    Hähnel, B.2    Rösener, S.3
  • 37
    • 0026663366 scopus 로고
    • Glomerular damage after uninephrectomy in young rats. II. Mechanical stress on podocytes as a pathway to sclerosis
    • Nagata M, Kriz W. Glomerular damage after uninephrectomy in young rats. II. Mechanical stress on podocytes as a pathway to sclerosis. Kidney Int 1992;42:148-160.
    • (1992) Kidney Int , vol.42 , pp. 148-160
    • Nagata, M.1    Kriz, W.2
  • 38
    • 0028322355 scopus 로고
    • Evidence for delayed-type hypersensitivity mechanisms in glomerular crescent formation
    • Huang XR, Holdsworth SR, Tipping PG. Evidence for delayed-type hypersensitivity mechanisms in glomerular crescent formation. Kidney Int 1994;46:69-78.
    • (1994) Kidney Int , vol.46 , pp. 69-78
    • Huang, X.R.1    Holdsworth, S.R.2    Tipping, P.G.3
  • 39
    • 0029081197 scopus 로고
    • Glomerular hypertrophy after subtotal nephrectomy: Relationship to early glomerular injury
    • Tenschert S, Elger M, Lemley KV. Glomerular hypertrophy after subtotal nephrectomy: Relationship to early glomerular injury. Virchows Arch 1995;426:509-517.
    • (1995) Virchows Arch , vol.426 , pp. 509-517
    • Tenschert, S.1    Elger, M.2    Lemley, K.V.3
  • 40
    • 0028914026 scopus 로고
    • Mitosis and presence of binucleate cells among glomerular podocytes in diseased human kidneys
    • Nagata M, Yamaguchi Y, Komatsu Y et al. Mitosis and presence of binucleate cells among glomerular podocytes in diseased human kidneys. Nephron 1995;70:68-71.
    • (1995) Nephron , vol.70 , pp. 68-71
    • Nagata, M.1    Yamaguchi, Y.2    Komatsu, Y.3
  • 41
    • 0016185860 scopus 로고
    • Extracapillary glomerulonephritis: A semiquantitative light-microscopical study of 59 patients
    • Olsen S. Extracapillary glomerulonephritis: A semiquantitative light-microscopical study of 59 patients. Acta Pathol Microbiol Scand Suppl 1974;249:7-19.
    • (1974) Acta Pathol Microbiol Scand Suppl , vol.249 , pp. 7-19
    • Olsen, S.1
  • 42
    • 0015080226 scopus 로고
    • An immuno-pathologic study of rapidly progressive glomerulonephritis in the adult
    • Lewis EJ, Cavallo T, Harrington JT et al. An immuno-pathologic study of rapidly progressive glomerulonephritis in the adult. Hum Pathol 1971;2:185-208.
    • (1971) Hum Pathol , vol.2 , pp. 185-208
    • Lewis, E.J.1    Cavallo, T.2    Harrington, J.T.3
  • 43
    • 0015547463 scopus 로고
    • The proximal tubule and the podocyte in cystinosis
    • Spear G. The proximal tubule and the podocyte in cystinosis. Nephron 1973;10:57-60.
    • (1973) Nephron , vol.10 , pp. 57-60
    • Spear, G.1
  • 44
    • 15244356577 scopus 로고    scopus 로고
    • The molecular requirements for cytokinesis
    • Glotzer M. The molecular requirements for cytokinesis. Science 2005;307:1735-1739.
    • (2005) Science , vol.307 , pp. 1735-1739
    • Glotzer, M.1
  • 45
    • 34848907421 scopus 로고    scopus 로고
    • Actin up: Regulation of podocyte structure and function by components of the actin cytoskeleton
    • DOI 10.1016/j.tcb.2007.06.006, PII S0962892407001675
    • Faul C, Asanuma K, Yanagida-Asanuma E et al. Actin up: Regulation of podocyte structure and function by components of the actin cytoskeleton. Trends Cell Biol 2007;17:428-437. (Pubitemid 47499042)
    • (2007) Trends in Cell Biology , vol.17 , Issue.9 , pp. 428-437
    • Faul, C.1    Asanuma, K.2    Yanagida-Asanuma, E.3    Kim, K.4    Mundel, P.5
  • 46
    • 33646401549 scopus 로고    scopus 로고
    • Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization
    • Verma R, Kovari I, Soofi A et al. Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J Clin Invest 2006;116:1346-1359.
    • (2006) J Clin Invest , vol.116 , pp. 1346-1359
    • Verma, R.1    Kovari, I.2    Soofi, A.3
  • 47
    • 32444451549 scopus 로고    scopus 로고
    • Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes
    • Remuzzi G, Benigni A, Remuzzi A. Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes. J Clin Invest 2006;116:288-296.
    • (2006) J Clin Invest , vol.116 , pp. 288-296
    • Remuzzi, G.1    Benigni, A.2    Remuzzi, A.3
  • 48
    • 24344458583 scopus 로고    scopus 로고
    • Is regression of chronic nephropathies a therapeutic target?
    • Remuzzi G, Remuzzi A. Is regression of chronic nephropathies a therapeutic target? J Am Soc Nephrol 2005;16:840-842.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 840-842
    • Remuzzi, G.1    Remuzzi, A.2
  • 49
    • 0036014932 scopus 로고    scopus 로고
    • Transforming growth factorbeta induces renal epithelial jagged-1 expression in fibrotic disease
    • Morrissey J, Guo G, Moridaira K et al. Transforming growth factorbeta induces renal epithelial jagged-1 expression in fibrotic disease. J Am Soc Nephrol 2002;13:1499-508.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1499-1508
    • Morrissey, J.1    Guo, G.2    Moridaira, K.3
  • 50
    • 40449112321 scopus 로고    scopus 로고
    • The Notch pathway in podocytes plays a role in the development of glomerular disease
    • Niranjan T, Bielesz B, Gruenwald A et al. The Notch pathway in podocytes plays a role in the development of glomerular disease. Nat Med 2008;14:290-298.
    • (2008) Nat Med , vol.14 , pp. 290-298
    • Niranjan, T.1    Bielesz, B.2    Gruenwald, A.3
  • 51
    • 17644444238 scopus 로고    scopus 로고
    • Transforming growth factor beta is upregulated by podocytes in response to excess intraglomerular passage of proteins: A central pathway in progressive glomerulosclerosis
    • Abbate M, Zoja C, Morigi M et al. Transforming growth factor beta is upregulated by podocytes in response to excess intraglomerular passage of proteins: A central pathway in progressive glomerulosclerosis. Am J Pathol 2002;161:2179-2193.
    • (2002) Am J Pathol , vol.161 , pp. 2179-2193
    • Abbate, M.1    Zoja, C.2    Morigi, M.3
  • 52
    • 48049124597 scopus 로고    scopus 로고
    • Ectopic notch activation in developing podocytes causes glomerulosclerosis
    • Waters AM, Wu MY, Onay T et al. Ectopic notch activation in developing podocytes causes glomerulosclerosis. J Am Soc Nephrol 2008;19:1139-1157.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1139-1157
    • Waters, A.M.1    Wu, M.Y.2    Onay, T.3
  • 53
    • 67649099271 scopus 로고    scopus 로고
    • The pathogenic role of notch activation in podocytes
    • Niranjan T, Murea M, Susztak K. The pathogenic role of notch activation in podocytes. Nephron Exp Nephrol 2009;111:e73-e79.
    • (2009) Nephron Exp Nephrol , vol.111
    • Niranjan, T.1    Murea, M.2    Susztak, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.