Changes in mRNA levels for brain-derived neurotrophic factor after wheel running in rats selectively bred for high- and low-aerobic capacity

Brain Research

Volumn 1425, Issue , 2011, Pages 90-97

  Groves Chapman, Jessica L ^a   Murray, Patrick S ^a   Stevens, Kristin L ^a,c   Monroe, Derek C ^a   Koch, Lauren G ^b   Britton, Steven L ^b   Holmes, Philip V ^a,c   Dishman, Rod K ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c University of Georgia   (United States)

Author keywords

Dose response; Hippocampus; Intrinsic fitness; Physical activity; Trophic factor

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA;

AEROBIC CAPACITY; AEROBIC EXERCISE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RNA ANALYSIS; RUNNING; SEDENTARY LIFESTYLE; STRAIN DIFFERENCE;

AGE FACTORS; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; BREEDING; CA1 REGION, HIPPOCAMPAL; EXERCISE TOLERANCE; MALE; MOTOR ACTIVITY; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; RUNNING;

ANIMALIA; ELAGATIS; RATTUS;

EID: 81155128618     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.09.059     Document Type: Article

References (52)

1. P.A. Adlard, and C.W. Cotman Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression Neuroscience 124 2004 985
2. P.A. Adlard, V.M. Perreau, and C.W. Cotman The exercise-induced expression of BDNF within the hippocampus varies across life-span Neurobiol. Aging 26 2005 511 520 (Pubitemid 40093934)
3. N.C. Berchtold, J.P. Kesslak, C.J. Pike, P.A. Adlard, and C.W. Cotman Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus Eur. J. Neurosci. 14 2001 1992 2002 (Pubitemid 35463686)
4. N.C. Berchtold, G. Chinn, M. Chou, J.P. Kesslak, and C.W. Cotman Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus Neuroscience 133 2005 853 861 (Pubitemid 40798336)
5. D.K. Binder, and H.E. Scharfman Brain-derived neurotrophic factor Growth Factors 22 2004 123 131 (Pubitemid 39377904)
6. A. Bjornebekk, A.A. Mathe, and S. Brene The antidepressant effect of running is associated with increased hippocampal cell proliferation Int. J. Neuropsychopharmacol. 8 2005 357 368 (Pubitemid 41002490)
7. M.J. Chen, and A.A. Russo-Neustadt Exercise activates the phosphatidylinositol 3-kinase pathway Brain Res. Mol. Brain Res. 135 2005 181 193 (Pubitemid 40602410)
8. R.K. Dishman, H.R. Berthoud, F.W. Booth, C.W. Cotman, V.R. Edgerton, M.R. Fleshner, S.C. Gandevia, F. Gomez-Pinilla, B.N. Greenwood, C.H. Hillman, A.F. Kramer, B.E. Levin, T.H. Moran, A.A. Russo-Neustadt, J.D. Salamone, J.D. Van Hoomissen, C.E. Wade, D.A. York, and M.J. Zigmond Neurobiology of exercise Obesity (Silver Spring) 14 2006 345 356 (Pubitemid 46219751)
9. C.H. Duman, L. Schlesinger, D.S. Russell, and R.S. Duman Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice Brain Res. 1199 2008 148 158
10. E. Erdfelder, F. Faul, and A. Buchner GPOWER: a general power analysis program Behav. Res. Methods 28 1996 1 11 (Pubitemid 126416697)
11. J. Farmer, X. Zhao, H. van Praag, K. Wodtke, F.H. Gage, and B.R. Christie Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo Neuroscience 124 2004 71 79 (Pubitemid 38186618)
12. A. Farovik, L.M. Dupont, and H. Eichenbaum Distinct roles for dorsal CA3 and CA1 in memory for sequential nonspatial events Learn. Mem. 17 2010 12 17
13. A.A. Garza, T.G. Ha, C. Garcia, M.J. Chen, and A.A. Russo-Neustadt Exercise, antidepressant treatment, and BDNF mRNA expression in the aging brain Pharmacol. Biochem. Behav. 77 2004 209 220 (Pubitemid 38125152)
14. O.L. Gobbo, and S.M. O'Mara Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor Behav. Brain Res. 159 2005 21 26 (Pubitemid 40410581)
15. F. Gomez-Pinilla, S. Vaynman, and Z. Ying Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition Eur. J. Neurosci. 28 2008 2278 2287
16. B.N. Greenwood, P.V. Strong, T.E. Foley, and M. Fleshner A behavioral analysis of the impact of voluntary physical activity on hippocampus-dependent contextual conditioning Hippocampus 19 2009 988 1001
17. G.S. Griesbach, D.A. Hovda, R. Molteni, A. Wu, and F. Gomez-Pinilla Voluntary exercise following traumatic brain injury: brain-derived neurotrophic factor upregulation and recovery of function Neuroscience 125 2004 129 139 (Pubitemid 38402166)
18. G.S. Griesbach, D.A. Hovda, F. Gomez-Pinilla, and R.L. Sutton Voluntary exercise or amphetamine treatment, but not the combination, increases hippocampal brain-derived neurotrophic factor and synapsin I following cortical contusion injury in rats Neuroscience 154 2008 530 540
19. J. Hoge, and R.P. Kesner Role of CA3 and CA1 subregions of the dorsal hippocampus on temporal processing of objects Neurobiol. Learn. Mem. 88 2007 225 231 (Pubitemid 47241225)
20. P.V. Holmes, H.S. Yoo, and R.K. Dishman Voluntary exercise and clomipramine treatment elevate prepro-galanin mRNA levels in the locus coeruleus in rats Neurosci. Lett. 408 2006 1 4 (Pubitemid 44466193)
21. R.A. Howlett, S.D. Kirkton, N.C. Gonzalez, H.E. Wagner, S.L. Britton, L.G. Koch, and P.D. Wagner Peripheral oxygen transport and utilization in rats following continued selective breeding for endurance running capacity J. Appl. Physiol. 106 2009 1819 1825
22. M.A. Høydal, U. Wisloff, O.J. Kemi, and O. Ellingsen Running speed and maximal oxygen uptake in rats and mice: practical implications for exercise training Eur. J. Cardiovasc. Prev. Rehabil. 14 2007 753 760 (Pubitemid 350197002)
23. R.A. Johnson, and G.S. Mitchell Exercise-induced changes in hippocampal brain-derived neurotrophic factor and neurotrophin-3: effects of rat strain Brain Res. 983 2003 108 114 (Pubitemid 36952572)
24. R.A. Johnson, J.S. Rhodes, S.L. Jeffrey, T. Garland Jr., and G.S. Mitchell Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running Neuroscience 121 2003 1 7 (Pubitemid 37297608)
25. M.W. Kim, M.S. Bang, T.R. Han, Y.J. Ko, B.W. Yoon, J.H. Kim, L.M. Kang, K.M. Lee, and M.H. Kim Exercise increased BDNF and trkB in the contralateral hemisphere of the ischemic rat brain Brain Res. 1052 2005 16 21
26. T. Kitamura, M. Mishina, and H. Sugiyama Enhancement of neurogenesis by running wheel exercises is suppressed in mice lacking NMDA receptor epsilon 1 subunit Neurosci. Res. 47 2003 55 63 (Pubitemid 36993875)
27. A.Y. Klintsova, E. Dickson, R. Yoshida, and W.T. Greenough Altered expression of BDNF and its high-affinity receptor TrkB in response to complex motor learning and moderate exercise Brain Res. 1028 2004 92 104 (Pubitemid 39429465)
28. L.G. Koch, and S.L. Britton Artificial selection for intrinsic aerobic endurance running capacity in rats Physiol. Genomics 5 2001 45 52 (Pubitemid 33675201)
29. L.G. Koch, and S.L. Britton Divergent selection for aerobic capacity in rats as a model for complex disease Integr. Comp. Biol. 45 2005 405
30. L.G. Koch, and S.L. Britton Development of animal models to test the fundamental basis of gene-environment interactions Obesity (Silver Spring) 16 Suppl. 3 2008 S28 S32
31. S.A. Neeper, F. Gomez-Pinilla, J. Choi, and C.W. Cotman Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain Brain Res. 726 1996 49 56 (Pubitemid 26292229)
32. C.M. Novak, C. Escande, P.R. Burghardt, M. Zhang, M.T. Barbosa, E.N. Chini, S.L. Britton, L.G. Koch, H. Akil, and J.A. Levine Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity Horm. Behav. 58 3 2010 355 367
33. H.S. Oliff, N.C. Berchtold, P. Isackson, and C.W. Cotman Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus Brain Res. Mol. Brain Res. 61 1998 147 153 (Pubitemid 28511357)
34. A.K. Olson, B.D. Eadie, C. Ernst, and B.R. Christie Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways Hippocampus 16 2006 250 260
35. Rasband, W.S., 1997-2011. Image J. Vol., eds. National Institutes of Health, Bethesda, MA, USA.
36. P. Rasmussen, P. Brassard, H. Adser, M.V. Pedersen, L. Leick, E. Hart, N.H. Secher, B.K. Pedersen, and H. Pilegaard Evidence for a release of brain-derived neurotrophic factor from the brain during exercise Exp. Physiol. 94 2009 1062 1069
37. J.I. Reiss, R.K. Dishman, H.E. Boyd, J.K. Robinson, and P.V. Holmes Chronic activity wheel running reduces the severity of kainic acid-induced seizures in the rat: possible role of galanin Brain Res. 1266 2009 54 63
38. M. Remondes, and E.M. Schuman Role for a cortical input to hippocampal area CA1 in the consolidation of a long-term memory Nature 431 2004 699 703 (Pubitemid 39382617)
39. J.S. Rhodes, H. van Praag, S. Jeffrey, I. Girard, G.S. Mitchell, T. Garland Jr., and F.H. Gage Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running Behav. Neurosci. 117 2003 1006 1016 (Pubitemid 37243783)
40. M.S. Rosenberg The file-drawer problem revisited: a general weighted method for calculating fail-safe numbers in meta-analysis Evolution 59 2005 464 468 (Pubitemid 40356057)
41. A. Russo-Neustadt, R.C. Beard, and C.W. Cotman Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression Neuropsychopharmacology 21 1999 679 682 (Pubitemid 29486636)
42. A.A. Russo-Neustadt, R.C. Beard, Y.M. Huang, and C.W. Cotman Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus Neuroscience 101 2000 305 312
43. A. Russo-Neustadt, T. Ha, R. Ramirez, and J.P. Kesslak Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model Behav. Brain Res. 120 2001 87 95 (Pubitemid 32118151)
44. A.A. Russo-Neustadt, H. Alejandre, C. Garcia, A.S. Ivy, and M.J. Chen Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise Neuropsychopharmacology 29 2004 2189 2199 (Pubitemid 39578909)
45. H. Scharfman, J. Goodman, A. Macleod, S. Phani, C. Antonelli, and S. Croll Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats Exp. Neurol. 192 2005 348 356 (Pubitemid 40347259)
46. H. Soya, T. Nakamura, C.C. Deocaris, A. Kimpara, M. Iimura, T. Fujikawa, H. Chang, B.S. McEwen, and T. Nishijima BDNF induction with mild exercise in the rat hippocampus Biochem. Biophys. Res. Commun. 358 2007 961 967 (Pubitemid 46828982)
47. L. Tong, H. Shen, V.M. Perreau, R. Balazs, and C.W. Cotman Effects of exercise on gene-expression profile in the rat hippocampus Neurobiol. Dis. 8 2001 1046 1056 (Pubitemid 34017098)
48. J.D. Van Hoomissen, H.O. Chambliss, P.V. Holmes, and R.K. Dishman Effects of chronic exercise and imipramine on mRNA for BDNF after olfactory bulbectomy in rat Brain Res. 974 2003 228 235 (Pubitemid 36549237)
49. S. Vaynman, Z. Ying, and F. Gomez-Pinilla Exercise induces BDNF and synapsin I to specific hippocampal subfields J. Neurosci. Res. 76 2004 356 362 (Pubitemid 38580130)
50. J. Widenfalk, L. Olson, and P. Thoren Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain Neurosci. Res. 34 1999 125 132
51. H.N. Zhang, and M.C. Ko Seizure activity involved in the up-regulation of BDNF mRNA expression by activation of central mu opioid receptors Neuroscience 161 2009 301 310
52. H. Zheng, Y. Liu, W. Li, B. Yang, D. Chen, X. Wang, Z. Jiang, H. Wang, Z. Wang, G. Cornelisson, and F. Halberg Beneficial effects of exercise and its molecular mechanisms on depression in rats Behav. Brain Res. 168 2006 47 55 (Pubitemid 43152052)