Influence of cellular location of expressed antigen on the efficacy of DNA vaccination: Cytotoxic T lymphocyte and antibody responses are suboptimal when antigen is cytoplasmic after intramuscular DNA immunization

International Immunology

Volumn 9, Issue 12, 1997, Pages 1897-1906

  Boyle, Jefferey S ^a   Koniaras, Christina ^a   Lew, Andrew M ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Cellular localization; Cytoplasmic; Genetic vaccine; IgG subclass; Membrane bound; Ovalbumin

Indexed keywords

CD4 ANTIGEN; DNA VACCINE; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELLULAR DISTRIBUTION; CYTOTOXIC T LYMPHOCYTE; FEMALE; INTRADERMAL DRUG ADMINISTRATION; INTRAMUSCULAR DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; VACCINATION;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; ANTIGENS, CD8; CELL MEMBRANE; CYTOPLASM; DNA; FEMALE; IMMUNOGLOBULIN G; INJECTIONS, INTRAMUSCULAR; MICE; MICE, INBRED C57BL; OVALBUMIN; T-LYMPHOCYTES, CYTOTOXIC; VACCINATION; VACCINES, DNA;

EID: 0031468120     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/9.12.1897     Document Type: Article

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