메뉴 건너뛰기




Volumn 13, Issue 9, 2011, Pages 4311-4323

Multifunctional antitumor magnetite/chitosan-L-glutamic acid (core/shell) nanocomposites

Author keywords

Biodegradable nanoparticle; Cancer; Doxorubicin; Hyperthermia; Magnetically responsive drug nanocarrier; Multifunctional nanoformulation; Nanomedicine

Indexed keywords

BIODEGRADABLE NANOPARTICLE; CANCER; DOXORUBICIN; HYPERTHERMIA; MULTIFUNCTIONAL NANOFORMULATION; NANOCARRIERS; NANOMEDICINES;

EID: 81055156324     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-011-0378-z     Document Type: Article
Times cited : (29)

References (50)
  • 1
    • 33847109294 scopus 로고    scopus 로고
    • Magnetic PNIPA hydrogels for hyperthermia applications in cancer therapy
    • doi:10.1016/j. msec.2006.05.027
    • Ang KL, Venkatraman S, Ramanujan RV (2007) Magnetic PNIPA hydrogels for hyperthermia applications in cancer therapy. Mater Sci Eng C 27:347-351. doi:10.1016/j. msec.2006.05.027
    • (2007) Mater Sci Eng C , vol.27 , pp. 347-351
    • Ang, K.L.1    Venkatraman, S.2    Ramanujan, R.V.3
  • 2
    • 55249095515 scopus 로고    scopus 로고
    • Novel strategies to improve the anticancer action of 5-fluorouracil by using drug delivery systems
    • doi:10.3390/molecules13102340
    • Arias JL (2008) Novel strategies to improve the anticancer action of 5-fluorouracil by using drug delivery systems. Molecules 13:2340-2369. doi:10.3390/molecules13102340
    • (2008) Molecules , vol.13 , pp. 2340-2369
    • Arias, J.L.1
  • 3
    • 78650910950 scopus 로고    scopus 로고
    • Drug targeting strategies in cancer treatment: An overview
    • doi:10.2174/138955711793564024
    • Arias JL (2011) Drug targeting strategies in cancer treatment: an overview. Mini Rev Med Chem 11:1-17. doi:10.2174/ 138955711793564024
    • (2011) Mini Rev Med Chem , vol.11 , pp. 1-17
    • Arias, J.L.1
  • 4
    • 0035856766 scopus 로고    scopus 로고
    • Synthesis and characterization of poly(ethyl-2-cyanoacrylate) nanoparticles with a magnetic core
    • doi:10.1016/S0168-3659(01)00519-3
    • Arias JL, Gallardo V, Gómez-Lopera SA, Plaza RC, Delgado AV (2001) Synthesis and characterization of poly(ethyl-2-cyanoacrylate) nanoparticles with a magnetic core. J Control Release 77:309-321. doi:10.1016/S0168-3659(01) 00519-3
    • (2001) J Control Release , vol.77 , pp. 309-321
    • Arias, J.L.1    Gallardo, V.2    Gómez-Lopera, S.A.3    Plaza, R.C.4    Delgado, A.V.5
  • 5
    • 33646943869 scopus 로고    scopus 로고
    • Preparation and characterization of carbonyl iron/poly (butylcyanoacrylate) core/shell nanoparticles
    • doi:10.1016/j.jcis.2006.03.005
    • Arias JL, Gallardo V, Linares-Molinero F, Delgado AV (2006) Preparation and characterization of carbonyl iron/poly (butylcyanoacrylate) core/shell nanoparticles. J Colloid Interface Sci 299:599-607. doi:10.1016/j.jcis.2006.03. 005
    • (2006) J Colloid Interface Sci , vol.299 , pp. 599-607
    • Arias, J.L.1    Gallardo, V.2    Linares-Molinero, F.3    Delgado, A.V.4
  • 6
    • 34248579025 scopus 로고    scopus 로고
    • Ftorafur loading and controlled release from poly(ethyl-2-cyanoacrylate) and poly(butylcyanoacrylate) nanospheres
    • doi:10.1016/j.ijpharm.2006.12.023
    • Arias JL, Gallardo V, Ruiz MA, Delgado AV (2007) Ftorafur loading and controlled release from poly(ethyl-2-cyanoacrylate) and poly(butylcyanoacrylate) nanospheres. Int J Pharm 337:282-290. doi:10.1016/j.ijpharm.2006.12.023
    • (2007) Int J Pharm , vol.337 , pp. 282-290
    • Arias, J.L.1    Gallardo, V.2    Ruiz, M.A.3    Delgado, A.V.4
  • 7
    • 47949094392 scopus 로고    scopus 로고
    • Magnetoresponsive squalenoyl gemcitabine composite nanoparticles for cancer active targeting
    • doi:10.1021/ la800547s
    • Arias JL, Reddy LH, Couvreur P (2008) Magnetoresponsive squalenoyl gemcitabine composite nanoparticles for cancer active targeting. Langmuir 24:7512-7519. doi:10.1021/ la800547s
    • (2008) Langmuir , vol.24 , pp. 7512-7519
    • Arias, J.L.1    Reddy, L.H.2    Couvreur, P.3
  • 8
    • 70350443227 scopus 로고    scopus 로고
    • Polymeric nanoparticulate system augmented the anticancer therapeutic efficacy of gemcitabine
    • doi:10.1080/10611860903105739
    • Arias JL, Reddy LH, Couvreur P (2009) Polymeric nanoparticulate system augmented the anticancer therapeutic efficacy of gemcitabine. J Drug Target 17:586-598. doi:10.1080/10611860903105739
    • (2009) J Drug Target , vol.17 , pp. 586-598
    • Arias, J.L.1    Reddy, L.H.2    Couvreur, P.3
  • 9
    • 77949675463 scopus 로고    scopus 로고
    • Formulation of chitosan nanoparticles loaded with metronidazole for the treatment of infectious diseases
    • doi:10.2174/157018010790225831
    • Arias JL, Martínez-Soler GI, López-Viota M, Ruiz MA (2010a) Formulation of chitosan nanoparticles loaded with metronidazole for the treatment of infectious diseases. Lett Drug Des Discov 7:70-78. doi:10.2174/ 157018010790225831
    • (2010) Lett Drug des Discov , vol.7 , pp. 70-78
    • Arias, J.L.1    Martínez-Soler, G.I.2    López-Viota, M.3    Ruiz, M.A.4
  • 10
    • 77952524536 scopus 로고    scopus 로고
    • Chitosan nanoparticles as a new delivery system for the chemotherapy agent tegafur
    • doi:10.3109/03639040903517914
    • Arias JL, López-Viota M, Gallardo V, Ruiz MA (2010b) Chitosan nanoparticles as a new delivery system for the chemotherapy agent tegafur. Drug Dev Ind Pharm 36:744-750. doi:10.3109/03639040903517914
    • (2010) Drug Dev Ind Pharm , vol.36 , pp. 744-750
    • Arias, J.L.1    López-Viota, M.2    Gallardo, V.3    Ruiz, M.A.4
  • 11
    • 25844492985 scopus 로고    scopus 로고
    • Preparation and characterization of chitosan-based nanoparticles
    • doi:10.1021/bm0502258
    • Bodnar M, Hartmann JF, Borbely J (2005) Preparation and characterization of chitosan-based nanoparticles. Biomacromolecules 6:2521-2527. doi:10.1021/bm0502258
    • (2005) Biomacromolecules , vol.6 , pp. 2521-2527
    • Bodnar, M.1    Hartmann, J.F.2    Borbely, J.3
  • 12
    • 37249016424 scopus 로고    scopus 로고
    • Battling tumors with magnetic nanotherapeutics and hyperthermia: Turning up the heat
    • doi:10.2217/17435889. 2.5.649
    • Campbell RB (2007) Battling tumors with magnetic nanotherapeutics and hyperthermia: turning up the heat. Nanomedicine 2:649-652. doi:10.2217/17435889. 2.5.649
    • (2007) Nanomedicine , vol.2 , pp. 649-652
    • Campbell, R.B.1
  • 13
    • 57049187105 scopus 로고    scopus 로고
    • Gelatin-coated magnetic iron oxide nanoparticles as carrier system: Drug loading and in vitro drug release study
    • doi:10.1016/j.ijpharm.2008.08.020
    • Gaihre B, Khil MS, Lee DR, Kim HY (2009) Gelatin-coated magnetic iron oxide nanoparticles as carrier system: drug loading and in vitro drug release study. Int J Pharm 365:180-189. doi:10.1016/j.ijpharm.2008.08.020
    • (2009) Int J Pharm , vol.365 , pp. 180-189
    • Gaihre, B.1    Khil, M.S.2    Lee, D.R.3    Kim, H.Y.4
  • 14
    • 27444446307 scopus 로고    scopus 로고
    • Synthesis, properties, and applications of iron nanoparticles
    • doi:10.1002/smll. 200500006
    • Huber DL (2005) Synthesis, properties, and applications of iron nanoparticles. Small 1:482-501. doi:10.1002/smll. 200500006
    • (2005) Small , vol.1 , pp. 482-501
    • Huber, D.L.1
  • 15
    • 0026315865 scopus 로고
    • Blood clearance of dextran magnetite particles determined by a noninvasive in vivo ESR method
    • doi:10.1002/ mrm.1910220251
    • Iannone A, Magin RL, Walczack T, Federico M, Swartz HM, Tomasi A, Vannini V (1991) Blood clearance of dextran magnetite particles determined by a noninvasive in vivo ESR method. Magn Reson Med 22:435-442. doi:10.1002/ mrm.1910220251
    • (1991) Magn Reson Med , vol.22 , pp. 435-442
    • Iannone, A.1    Magin, R.L.2    Walczack, T.3    Federico, M.4    Swartz, H.M.5    Tomasi, A.6    Vannini, V.7
  • 16
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmaceutical excipient
    • doi:10.1023/A: 1011929016601
    • Illum L (1998) Chitosan and its use as a pharmaceutical excipient. Pharm Res 15:1326-1331. doi:10.1023/A: 1011929016601
    • (1998) Pharm Res , vol.15 , pp. 1326-1331
    • Illum, L.1
  • 17
    • 27644542061 scopus 로고    scopus 로고
    • Medical application of functionalized magnetic nanoparticles
    • doi:10.1263/jbb.100.1
    • Ito A, Shinkai M, Honda H, Kobayashi T (2005) Medical application of functionalized magnetic nanoparticles. J Biosci Bioeng 100:1-11. doi:10.1263/jbb.100.1
    • (2005) J Biosci Bioeng , vol.100 , pp. 1-11
    • Ito, A.1    Shinkai, M.2    Honda, H.3    Kobayashi, T.4
  • 19
    • 64249104383 scopus 로고    scopus 로고
    • Probing temperaturesensitive behavior of pNIPAAm-coated iron oxide nanoparticles using frequency-dependent magnetic measurements
    • doi:10. 1016/j.jmmm.2009.02.134
    • Kalele S, Narain R, Krishnan KM (2009) Probing temperaturesensitive behavior of pNIPAAm-coated iron oxide nanoparticles using frequency-dependent magnetic measurements. J Magn Magn Mater 321:1377-1380. doi:10. 1016/j.jmmm.2009.02.134
    • (2009) J Magn Magn Mater , vol.321 , pp. 1377-1380
    • Kalele, S.1    Narain, R.2    Krishnan, K.M.3
  • 20
    • 0001366447 scopus 로고
    • Determination of the isoelectric points of severalmetals by an adhesionmethod
    • doi:10.1021/j100171a056
    • Kallay N, Torbić Ž, Golić M, Matijević E (1991) Determination of the isoelectric points of severalmetals by an adhesionmethod. J Phys Chem 95:7028-7032. doi:10.1021/j100171a056
    • (1991) J Phys Chem , vol.95 , pp. 7028-7032
    • Kallay, N.1    Torbić, Ž.2    Golić, M.3    Matijević, E.4
  • 21
    • 8544262966 scopus 로고    scopus 로고
    • Magnetic and hydrogel composite materials for hyperthermia applications
    • doi:10.1023/B:JMSM. 0000046386.78633.e5
    • Lao LL, Ramanujan RV (2004) Magnetic and hydrogel composite materials for hyperthermia applications. J Mater Sci Mater Med 15:1061-1064. doi:10.1023/B:JMSM. 0000046386.78633.e5
    • (2004) J Mater Sci Mater Med , vol.15 , pp. 1061-1064
    • Lao, L.L.1    Ramanujan, R.V.2
  • 22
    • 47249140441 scopus 로고    scopus 로고
    • Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications
    • doi:10.1021/cr068445e
    • Laurent S, Forge D, Port M, Roch A, Robic C, Elst LV, Muller RN (2008) Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem Rev 108: 2064-2110. doi:10.1021/cr068445e
    • (2008) Chem Rev , vol.108 , pp. 2064-2110
    • Laurent, S.1    Forge, D.2    Port, M.3    Roch, A.4    Robic, C.5    Elst, L.V.6    Muller, R.N.7
  • 23
    • 0029145701 scopus 로고
    • Methotrexate-loaded nanoparticles: Analysis of drug content and study of the matrix structure
    • doi:10.3109/03639049509069263
    • Llovet MI, Egea MA, Valero J, Alsina MA, García ML, Chauvet A (1995) Methotrexate-loaded nanoparticles: analysis of drug content and study of the matrix structure. Drug Dev Ind Pharm 21:1761-1771. doi:10.3109/ 03639049509069263
    • (1995) Drug Dev Ind Pharm , vol.21 , pp. 1761-1771
    • Llovet, M.I.1    Egea, M.A.2    Valero, J.3    Alsina, M.A.4    García, M.L.5    Chauvet, A.6
  • 24
    • 0012849191 scopus 로고    scopus 로고
    • The role of surface conduction in the development of electrokinetics
    • Delgado AV (ed) Marcel Dekker, New York
    • Lyklema J (2002) The role of surface conduction in the development of electrokinetics. In: Delgado AV (ed) Interfacial electrokinetics and electrophoresis. Marcel Dekker, New York, pp 87-98
    • (2002) Interfacial Electrokinetics and Electrophoresis , pp. 87-98
    • Lyklema, J.1
  • 25
    • 0006952662 scopus 로고
    • Infrared absorption spectroscopy
    • Zussman J (ed) Academic Press, London/New York
    • Lyon RJP (1967) Infrared absorption spectroscopy. In: Zussman J (ed) Physical methods in determinative mineralogy. Academic Press, London/New York, pp 371-399
    • (1967) Physical Methods in Determinative Mineralogy , pp. 371-399
    • Lyon, R.J.P.1
  • 26
    • 0019541337 scopus 로고
    • Preparation of aqueous magnetic liquids in alkaline and acidicmedia
    • doi:10.1109/TMAG.1981.1061188
    • Massart R (1981) Preparation of aqueous magnetic liquids in alkaline and acidicmedia. IEEE Trans Magn 17:1247-1248. doi:10.1109/TMAG.1981.1061188
    • (1981) IEEE Trans Magn , vol.17 , pp. 1247-1248
    • Massart, R.1
  • 27
    • 0035980981 scopus 로고    scopus 로고
    • Enzyme-activated targeting of liposomes
    • doi:10.1016/S0169-409X01)00205-8
    • Meers P (2001) Enzyme-activated targeting of liposomes. Adv Drug Deliv Rev 53:265-272. doi:10.1016/S0169-409X (01)00205-8
    • (2001) Adv Drug Deliv Rev , vol.53 , pp. 265-272
    • Meers, P.1
  • 28
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • doi:10.1124/pr.56.2.6
    • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L (2004) Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 56:185-229. doi:10.1124/pr.56.2.6
    • (2004) Pharmacol Rev , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 29
    • 0030581141 scopus 로고    scopus 로고
    • Cytotoxicity of magnetite-loaded polylactide, polylactide/ glycolide particles and solid lipid nanoparticles
    • doi:10.1016/0378-5173(96)04539-5
    • Müller RH, Maaßen S, Weyhers H, Specht F, Lucks JS (1996) Cytotoxicity of magnetite-loaded polylactide, polylactide/ glycolide particles and solid lipid nanoparticles. Int J Pharm 138:85-94. doi:10.1016/0378-5173(96) 04539-5
    • (1996) Int J Pharm , vol.138 , pp. 85-94
    • Müller, R.H.1    Maaßen, S.2    Weyhers, H.3    Specht, F.4    Lucks, J.S.5
  • 30
    • 0035981024 scopus 로고    scopus 로고
    • The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors
    • doi:10.1016/S0169-409X(01)00233-2
    • Needham D, Dewhirst MW (2001) The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors. Adv Drug Deliv Rev 53:285-305. doi:10.1016/S0169-409X(01)00233-2
    • (2001) Adv Drug Deliv Rev , vol.53 , pp. 285-305
    • Needham, D.1    Dewhirst, M.W.2
  • 31
    • 0034161921 scopus 로고    scopus 로고
    • A new temperature-sensitive liposome for use with mild hyperthermia: Characterization and testing in a human tumor xenograft model
    • Needham D, Anyarambhatla G, Kong G, Dewhirst MW (2000) A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model. Cancer Res 60:1197-1201
    • (2000) Cancer Res , vol.60 , pp. 1197-1201
    • Needham, D.1    Anyarambhatla, G.2    Kong, G.3    Dewhirst, M.W.4
  • 32
    • 0027962204 scopus 로고
    • Degradation of fully water-soluble, partially N-acetylated chitosans with lysozyme
    • doi:10.1016/0144-8617(94)90187-2
    • Nordtveit RJ, Vårum KM, Smidsrød O (1994) Degradation of fully water-soluble, partially N-acetylated chitosans with lysozyme. Carbohydr Polym 23:253-260. doi:10.1016/ 0144-8617(94)90187-2
    • (1994) Carbohydr Polym , vol.23 , pp. 253-260
    • Nordtveit, R.J.1    Vårum, K.M.2    Smidsrød, O.3
  • 33
    • 6744227162 scopus 로고
    • Electrophoretic mobility of a spherical colloidal particle
    • doi:10.1039/F29787401607
    • O'Brien RW, White LR (1978) Electrophoretic mobility of a spherical colloidal particle. J Chem Soc Faraday Trans 2:1607-1626. doi:10.1039/ F29787401607
    • (1978) J Chem Soc Faraday Trans , vol.2 , pp. 1607-1626
    • O'Brien, R.W.1    White, L.R.2
  • 35
    • 40849098801 scopus 로고    scopus 로고
    • Chitosan nanoparticles loaded with dorzolamide and pramipexole
    • doi:10.1016/j.carbpol.2007.11.007
    • Papadimitriou S, Bikiaris D, Avgoustakis K, Karavas E, Georgarakis M (2008) Chitosan nanoparticles loaded with dorzolamide and pramipexole. Carbohydr Polym 73:44-54. doi:10.1016/j.carbpol.2007.11.007
    • (2008) Carbohydr Polym , vol.73 , pp. 44-54
    • Papadimitriou, S.1    Bikiaris, D.2    Avgoustakis, K.3    Karavas, E.4    Georgarakis, M.5
  • 36
    • 0025213160 scopus 로고
    • The controlled parenteral delivery of polypeptides and proteins
    • doi:10. 1016/0378-517390)90108-G
    • Pitt CG (1990) The controlled parenteral delivery of polypeptides and proteins. Int J Pharm 59:173-196. doi:10. 1016/0378-5173(90)90108-G
    • (1990) Int J Pharm , vol.59 , pp. 173-196
    • Pitt, C.G.1
  • 38
    • 72149123663 scopus 로고    scopus 로고
    • Thermoresponsive magnetic composite nanomaterials for multimodal cancer therapy
    • doi:10.1016/j.actbio. 2009.07.004
    • Purushotham S, Ramanujan RV (2010) Thermoresponsive magnetic composite nanomaterials for multimodal cancer therapy. Acta Biomater 6:502-510. doi:10.1016/j.actbio. 2009.07.004
    • (2010) Acta Biomater , vol.6 , pp. 502-510
    • Purushotham, S.1    Ramanujan, R.V.2
  • 39
    • 2442656249 scopus 로고    scopus 로고
    • Combined cancer therapy by micellarencapsulated drug and ultrasound
    • doi:10.1016/j.ijpharm.2003.09.048
    • Rapoport N (2004) Combined cancer therapy by micellarencapsulated drug and ultrasound. Int J Pharm 277: 155-162. doi:10.1016/j.ijpharm.2003.09.048
    • (2004) Int J Pharm , vol.277 , pp. 155-162
    • Rapoport, N.1
  • 40
    • 0000509846 scopus 로고
    • Interfacial properties of zirconium dioxide and magnetite in water
    • doi:10.1016/ 0021-9797(83) 90370-3
    • Regazzoni AE, Blesa MA, Maroto AJG (1983) Interfacial properties of zirconium dioxide and magnetite in water. J Colloid Interface Sci 91(2):560-570. doi:10.1016/ 0021-9797(83)90370-3
    • (1983) J Colloid Interface Sci , vol.91 , Issue.2 , pp. 560-570
    • Regazzoni, A.E.1    Blesa, M.A.2    Maroto, A.J.G.3
  • 41
    • 0037778593 scopus 로고    scopus 로고
    • Effect of latex and plasticizer concentration on glucocorticoid release from ointments
    • Ruiz MA, Gallardo V, Arias JL, Delgado A (2003) Effect of latex and plasticizer concentration on glucocorticoid release from ointments. Pharm Ind 65:454-457
    • (2003) Pharm Ind , vol.65 , pp. 454-457
    • Ruiz, M.A.1    Gallardo, V.2    Arias, J.L.3    Delgado, A.4
  • 42
    • 59249088995 scopus 로고    scopus 로고
    • Preparation and properties of highly soluble chitosan-L-glutamic acid aerogel derivative
    • doi:10.1016/j.carbpol.2008.10.011
    • Singh J, Dutta PK, Dutta J, Hunt AJ, Macquarrie DJ, Clark JH (2009) Preparation and properties of highly soluble chitosan-L-glutamic acid aerogel derivative. Carbohydr Polym 76:188-195. doi:10.1016/j.carbpol.2008.10.011
    • (2009) Carbohydr Polym , vol.76 , pp. 188-195
    • Singh, J.1    Dutta, P.K.2    Dutta, J.3    Hunt, A.J.4    MacQuarrie, D.J.5    Clark, J.H.6
  • 44
    • 0035966497 scopus 로고    scopus 로고
    • Biodegradable polymeric nanoparticles as drug delivery devices
    • doi:10.1016/ S0168-365900)00339-4
    • Soppimath KS, Aminabhavi TM, Kulkarni AR, Rudzinski WE (2001) Biodegradable polymeric nanoparticles as drug delivery devices. J Control Release 70:1-20. doi:10.1016/ S0168-3659(00)00339-4
    • (2001) J Control Release , vol.70 , pp. 1-20
    • Soppimath, K.S.1    Aminabhavi, T.M.2    Kulkarni, A.R.3    Rudzinski, W.E.4
  • 45
    • 35349026762 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor effects of doxorubicin loaded with bacterial magnetosomes (DBMs) on H22 cells: The magnetic bio-nanoparticles as drug carriers
    • doi:10.1016/j.canlet.2007.08.018
    • Sun JB, Duan JH, Dai SL, Ren J, Zhang YD, Tian JS, Li Y (2007) In vitro and in vivo antitumor effects of doxorubicin loaded with bacterial magnetosomes (DBMs) on H22 cells: the magnetic bio-nanoparticles as drug carriers. Cancer Lett 258:109-117. doi:10.1016/j.canlet.2007.08.018
    • (2007) Cancer Lett , vol.258 , pp. 109-117
    • Sun, J.B.1    Duan, J.H.2    Dai, S.L.3    Ren, J.4    Zhang, Y.D.5    Tian, J.S.6    Li, Y.7
  • 47
    • 38649126187 scopus 로고    scopus 로고
    • Rationale for and measurement of liposomal drug delivery with hyperthermia using non-invasive imaging techniques
    • doi:10.1080/02656730701840147
    • Tashjian JA, Dewhirst MW, Needham D, Viglianti BL (2008) Rationale for and measurement of liposomal drug delivery with hyperthermia using non-invasive imaging techniques. Int J Hyperth 24:79-90. doi:10.1080/02656730701840147
    • (2008) Int J Hyperth , vol.24 , pp. 79-90
    • Tashjian, J.A.1    Dewhirst, M.W.2    Needham, D.3    Viglianti, B.L.4
  • 48
    • 0026530398 scopus 로고
    • Cross-linked chitosan microspheres: Preparation and evaluation as a matrix for the controlled release of pharmaceuticals
    • Thanoo BC, Sunny MC, Jayakrishnan A (1992) Cross-linked chitosan microspheres: preparation and evaluation as a matrix for the controlled release of pharmaceuticals. J Pharm Pharmacol 44:283-286
    • (1992) J Pharm Pharmacol , vol.44 , pp. 283-286
    • Thanoo, B.C.1    Sunny, M.C.2    Jayakrishnan, A.3
  • 49
    • 34249820576 scopus 로고    scopus 로고
    • Multifunctional nanocarriers
    • doi:10.1016/j.addr.2006.09.009
    • Torchilin VP (2006) Multifunctional nanocarriers. Adv Drug Deliv Rev 58:1532-1555. doi:10.1016/j.addr.2006.09.009
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1532-1555
    • Torchilin, V.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.