Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes

Human Reproduction

Volumn 26, Issue 12, 2011, Pages 3372-3387

  Kashir, Junaid ^a   Jones, Celine ^a   Lee, Hoi Chang ^b   Rietdorf, Katja ^c   Nikiforaki, Dimitra ^a   Durrans, Claire ^a   Ruas, Margarida ^c   Tee, Sze Tian ^a   Heindryckx, Bjorn ^d   Galione, Antony ^c   De Sutter, Petra ^d   Fissore, Rafael A ^b   Parrington, John ^c   Coward, Kevin ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

assisted oocyte activation; male infertility; oocyte activation; phophospholipase C zeta (PLCzeta); sperm

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; PHOSPHOLIPASE C; PHOSPHOLIPASE C ZETA; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CONFOCAL MICROSCOPY; FLUORESCENCE; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; OOCYTE; POINT MUTATION; PROTEIN LOCALIZATION; SPERM;

MAMMALIA;

EID: 81055146957     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/der336     Document Type: Article

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