Molecular identification of NAT8 as the enzyme that acetylates cysteine S-conjugates to mercapturic acids

Journal of Biological Chemistry

Volumn 285, Issue 24, 2010, Pages 18888-18898

  Veiga da Cunha, Maria ^a   Tyteca, Donatienne ^a   Stroobant, Vincent ^a   Courtoy, Pierre J ^a   Opperdoes, Fred R ^a   Van Schaftingen, Emile ^a  

^a DE DUVE INSTITUTE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOPLASMIC RETICULUM; ENZYMATIC ACTIVITIES; GENES ENCODING; GENOMIC DNA; L-CYSTEINE; MERCAPTURIC ACIDS; MICROSOMAL ENZYMES; MOLECULAR IDENTIFICATION; N-ACETYLASPARTATE; N-ACETYLATION; N-ACETYLTRANSFERASES; REACTION CATALYZED; SINGLE NUCLEOTIDE POLYMORPHISMS; VERTEBRATE GENOMES; XENOBIOTIC METABOLISM;

ACETYLATION; AMINATION; AMINO ACIDS; CONFOCAL MICROSCOPY; GENE ENCODING; ORGANIC ACIDS;

ENZYMES;

ACETYLCYSTEINE; ACYLTRANSFERASE; ARGININE; GENOMIC DNA; GLUTAMIC ACID; LEUKOTRIENE E4; LYSINE; METHIONINE; N ACETYLTRANSFERASE 8; PHENYLALANINE; SERINE; UNCLASSIFIED DRUG;

ACETYLATION; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CATALYSIS; CELL STRAIN HEK293; CONTROLLED STUDY; DNA SEQUENCE; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME ANALYSIS; EXPRESSED SEQUENCE TAG; GENE DUPLICATION; GENE MUTATION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; STOP CODON;

ACETYL COENZYME A; ACETYLATION; ACETYLCYSTEINE; ACETYLTRANSFERASES; CELL LINE; CODON, TERMINATOR; CYSTEINE; CYTOSOL; ENDOPLASMIC RETICULUM; HUMANS; MICROSCOPY, CONFOCAL; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; XENOBIOTICS;

PRIMATES; VERTEBRATA;

EID: 77953300281     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.110924     Document Type: Article

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