A novel comparative genomics analysis for common drug and vaccine targets in Corynebacterium pseudotuberculosis and other CMN group of human pathogens

Chemical Biology and Drug Design

Volumn 78, Issue 1, 2011, Pages 73-84

  Barh, Debmalya ^a,b   Jain, Neha ^a,c   Tiwari, Sandeep ^a,c   Parida, Bibhu Prasad ^a,b   D'Afonseca, Vivian ^d   Li, Liwei ^e   Ali, Amjad ^d   Santos, Anderson Rodrigues ^d   Guimarães, Luís Carlos ^d   de Castro Soares, Siomar ^d   Miyoshi, Anderson ^d   Bhattacharjee, Atanu ^f   Misra, Amarendra Narayan ^b   Silva, Artur ^g   Kumar, Anil ^c   Azevedo, Vasco ^d  

^a Institute of Integrative Omics and Applied Biotechnology   (India)

^b FAKIR MOHAN UNIVERSITY   (India)

^c DEVI AHILYA UNIVERSITY   (India)

^d FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f NORTH EASTERN HILL UNIVERSITY   (India)

^g FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

Corynebacterium pseudotuberculosis; Drug and vaccine targets; Minimal genome; Subtractive genomics

Indexed keywords

ABC TRANSPORTER; DIMETHYLALLYLTRANSFERASE; HYDROXYBENZOATE POLYPRENYLTRANSFERASE LIKE PRENYLTRANSFERASE; PHOSPHORIBOSE DIPHOSPHATE; RIBOSE PHOSPHATE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CORYNEBACTERIUM; CORYNEBACTERIUM DIPHTHERIAE; CORYNEBACTERIUM PSEUDOTUBERCULOSIS; DRUG TARGETING; GENE SEQUENCE; GENOME; GENOME ANALYSIS; HOST PATHOGEN INTERACTION; MOLECULAR DOCKING; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NOCARDIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL VACCINES; COMPARATIVE GENOMIC HYBRIDIZATION; CORYNEBACTERIUM PSEUDOTUBERCULOSIS; DRUG DESIGN; GENOME, BACTERIAL; HUMANS; MYCOBACTERIUM; NOCARDIA;

BOVINAE; CAPRA HIRCUS; CORYNEBACTERIUM; CORYNEBACTERIUM DIPHTHERIAE; CORYNEBACTERIUM PSEUDOTUBERCULOSIS; EQUIDAE; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NOCARDIA; OVIS ARIES;

EID: 80955179975     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2011.01118.x     Document Type: Article

References (58)

1. Bayan N., Houssin C., Chami M., Leblon G. (2003) Mycomembrane and S-layer: two important structures of Corynebacterium glutamicum cell envelope with promising biotechnology applications. J Biotechnol;104:55-67.
2. Hard G.C. (1969) Electron microscopic examination of Corynebacterium ovis. J Bacteriol;97:1480-1485.
3. Songer J.G., Beckenbach K., Marshall M.M., Olson G.B., Kelley L. (1988) Biochemical and genetic characterization of Corynebacterium pseudotuberculosis. Am J Vet Res;49:223-226.
4. Hall V., Collins M.D., Hutson R.A., Lawson P.A., Falsen E., Duerden B.I. (2003) Corynebacterium atypicum sp. nov., from a human clinical source, does not contain corynomycolic acids. Int J Syst Evol Microbiol;53:1065-1068.
5. Hard G.C. (1975) Comparative toxic effect of the surface lipid of Corynebacterium ovis on peritoneal macrophages. Infect Immun;12:1439-1449.
6. Dorella F.A., Pacheco L.G.C., Oliveira S.C., Miyoshi A., Azevedo V. (2006) Corynebacterium pseudotuberculosis: microbiology, biochemical properties, pathogenesis and molecular studies of virulence. Vet Res;37:201-218.
7. Williamson L.H. (2001) Caseous lymphadenitis in small ruminants. Vet Clin North Am Food Anim Pract;17:359-371.
8. Merchant I.A., Packer R.A. (1967) The genus corynebacterium. In: Merchant I.A., Packer R.A., editors. Veterinary Bacteriology and Virology. Iowa: The Iowa State University Press; p. 425-440.
9. Brown C.C., Olander H.J., Alves S.F. (1987) Synergistic hemolysis-inhibition titers associated with caseous lymphadenitis in a slaughterhouse survey of goats and sheep in Northeastern Brazil. Can J Vet Res;51:46-49.
10. Collett M.G., Bath G.F., Cameron C.M. (1994) Corynebacterium pseudotuberculosis infections. In: Coetzer J.A.W., Thomson G.R., Tustin R.C., Kriek N.P.J., editors. Infectious Diseases of Livestock with Special Reference to Southern Africa. Cape Town: Oxford University Press; p. 1387-1395.
11. Paton M., Walker S., Rose I., Watt G. (2003) Prevalence of caseous lymphadenitis and usage of caseous lymphadenitis vaccines in sheep flocks. Aust Vet J;81:91-95.
12. Unanian M., Silva A.F., Pant K. (1985) Abscesses and caseous lymphadenitis in goats in tropical semi-arid north-east Brazil. Tropic Anim Health Prod, 17:57-62.
13. Yeruham I., Elad D., Van-Ham M., Shpigel N.Y., Perl S. (1997) Corynebacterium pseudotuberculosis infection in Israeli cattle: clinical and epidemiological studies. Vet Rec;140:423-427.
14. Ben Saïd M.S., Ben Maitigue H., Benzarti M. et al. (2002) Epidemiological and clinical studies of ovine caseous lymphadenitis. Arch Inst Pasteur Tunis;79:51-57.
15. Binns S.H., Bailey M., Green L.E. (2002) Postal survey of ovine caseous lymphadenitis in the United Kingdom between 1990 and 1999. Vet Rec;150:263-268.
16. Connor K.M., Quirie M.M., Baird G., Donachie W. (2000) Characterization of United Kingdom isolates of Corynebacterium pseudotuberculosis using pulsed-field gel electrophoresis. J Clin Microbiol;38:2633-2637.
17. Paton M., Rose I., Hart R. et al. (1994) New infection with Corynebacterium pseudotuberculosis reduces wool production. Aust Vet J;71:47-49.
18. Arsenault J., Girard C., Dubreuil P. et al. (2003) Prevalence of and carcass condemnation from maedi-visna, paratuberculosis and caseous lymphadenitis in culled sheep from Quebec, Canada. Prev Vet Med;59:67-81.
19. Ayers J.L. (1977) Caseous lymphadenitis in goats and sheep: a review of diagnosis, pathogenesis, and immunity. J Am Vet Med Assoc;171:1251-1254.
20. Peel M.M., Palmer G.G., Stacpoole A.M., Kerr T.G. (1997) Human lymphadenitis due to Corynebacterium pseudotuberculosis: report of ten cases from Australia and review. Clin Infect Dis;24:185-191.
21. Paton M. (1993) Control of cheesy gland in sheep. West Aust J Agric;34:31-37.
22. Menzies P.I., Hwang Y.T., Prescott J.F. (2004) Comparison of an interferon-gamma to a phospholipase D enzyme-linked immunosorbent assay for diagnosis of Corynebacterium pseudotuberculosis infection in experimentally infected goats. Vet Microbiol;100:129-137.
23. Fontaine M.C., Baird G., Connor K.M., Rudge K., Sales J., Donachie W. (2006) Vaccination confers significant protection of sheep against infection with a virulent United Kingdom strain of Corynebacterium pseudotuberculosis. Vaccine;24:5986-5996.
24. Piontkowski M.D., Shivvers D.W. (1998) Evaluation of a commercially available vaccine against Corynebacterium pseudotuberculosis for use in sheep. J Am Vet Med Assoc;212:1765-1768.
25. Garg D.N., Nain S.P.S., Chandiramani N.K. (1985) Isolation and characterization of Corynebacterium ovis from sheep and goats. Indian Vet J;62:805-808.
26. Stanford K., Brogden K.A., McClelland L.A., Kozub G.C., Audibert F. (1998) The incidence of caseous lymphadenitis in Alberta sheep and assessment of impact by vaccination with commercial and experimental vaccines. Can J Vet Res;62:38-43.
27. D'Afonseca V., Prosdocimi F., Dorella F.A. et al. (2010) Survey of genome organization and gene content of Corynebacterium pseudotuberculosis. Microbiol Res;165:312-320.
28. Silva A., Schneider M.P., Cerdeira L. et al. (2010) Complete genome sequence of Corynebacterium pseudotuberculosis I-19, strain isolated from Israel Bovine mastitis. J Bacteriol; ;193:323-4.
29. Sakharkar K.R., Sakharkar M.K., Chow V.T.K. (2004) A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas Aeruginosa. In silico Biol;4:355-360.
30. Dutta A., Singh S.K., Ghosh P. et al. (2006) In silico identification of potential therapeutic targets in the human pathogen Helicobacter pylori. In silico Biol;6:43-47.
31. Chong C.E., Lim B.S., Nathan S., Mohamed R. (2006) In silico analysis of Burkholderia pseudomallei genome sequence for potential drug targets. In silico Biol;6:341-346.
32. Asif S.M., Asad A., Faizan A. et al. (2009) Dataset of potential targets for Mycobacterium tuberculosis H37Rv through comparative genome analysis. Bioinformation;4:245-248.
33. Barh D., Kumar A. (2009) In silico identification of candidate drug and vaccine targets from various pathways in Neisseria gonorrhoeae. In silico Biol;9:225-231.
34. Rathi B., Sarangi A.N., Trivedi N. (2009) Genome subtraction for novel target definition in Salmonella typhi. Bioinformation;4:143-150.
35. Gish W., States D.J. (1993) Identification of protein coding regions by database similarity search. Nat Genet;3:266-272.
36. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. (1990) Basic local alignment search tool. J Mol Biol;215:403-410.
37. Zhang R., Lin Y. (2009) DEG 5.0, a database of essential genes in both prokaryotes and eukaryotes. Nucleic Acids Res;37:D455-D458.
38. Kanehisa M., Goto S. (2000) KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res;28:27-30.
39. Jones D.T. (1999) Protein secondary structure prediction based on position-specific scoring matrices. J Mol Biol;292:195-202.
40. Irwin J.J., Shoichet B.K. (2005) ZINC - a free database of commercially available compounds for virtual screening. J Chem Inf Model;45:177-182.
41. Sharma V., Gupta P., Dixit A. (2008) In silico identification of putative drug targets from different metabolic pathways of Aeromonas hydrophila. In silico Biol;8:331-338.
42. Anishetty S., Pulimi M., Pennathur G. (2005) Potential drug targets in Mycobacterium tuberculosis through metabolic pathway analysis. Comput Biol Chem;29:368-378.
43. Leiting W.U., Jianping X.I.E. (2010) Comparative genomics analysis of Mycobacterium NrdH-redoxins. Microb Pathog;48:97-102.
44. Shanmugam A., Natarajan J. (2010) Computational genome analyses of metabolic enzymes in Mycobacterium leprae for drug target identification. Bioinformation;4:392-395.
45. Chhabra G., Sharma P., Anant A. et al. (2010) Identification and modeling of a drug target for Clostridium perfringens SM101. Bioinformation;4:278-289.
46. Barh D., Misra A.N. (2009) Scientific commons: epitope design from transporter targets in N. gonorrhoeae.
47. Driessen A.J.M., Haril U.F., Wickner W. (2003) The enzymology of protein translocation across the Escherichia coli plasma membrane.
48. Hasan S., Daugelat S., Rao P.S.S., Schreiber M. (2006) Prioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosis. PLoS Comp Biol;2:e61.
49. Perumal D., Lim C.S., Sakharkar K.R., Sakharkar M.K. (2007) Differential genome analyses of metabolic enzymes in Pseudomonas aeruginosa for drug target identification. In silico Biol;7:453-465.
50. Cho Y., Ioerger T.R., Sacchettini J.C. (2008) Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening. J Med Chem;51:5984-5992.
51. Huang H., Berg S., Spencer J.S. et al. (2008) Identification of amino acids and domains required for catalytic activity of DPPR synthase, a cell wall biosynthetic enzyme of Mycobacterium tuberculosis. Microbiology (Reading, England);154:736-743.
52. Alderwick L.J., Radmacher E., Seidel M. et al. (2005) Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core. J Biol Chem;280:32362-32371.
53. Ershov I.V. (2007) 2-C-methylerythritol phosphate pathway of isoprenoid biosynthesis as a target in identifying of new antibiotics, herbicides, and immunomodulators (Review). Prikl Biokhim Mikrobiol;43:133-157.
54. Eoh H., Brennan P.J., Crick D.C. (2009) The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target. Tuberculosis (Edinburgh, Scotland);89:1-11.
55. Brown A.C., Parish T. (2008) Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake. BMC Microbiol;8:78.
56. Shigi Y. (1989) Inhibition of bacterial isoprenoid synthesis by fosmidomycin, a phosphonic acid-containing antibiotic. J Antimicrobial Chemother;24:131-145.
57. Watson R.J., Heys R., Martin T., Savard M. (2001) Sinorhizobium meliloti cells require biotin and either cobalt or methionine for growth. Appl Environ Microbiol;67:3767-3770.
58. Jordan A., Aslund F., Pontis E., Reichard P., Holmgren A. (1997) Characterization of Escherichia coli NrdH. A glutaredoxin-like protein with a thioredoxin-like activity profile. J Biol Chem;272:18044-18050.